Edit concept Question Editor Create issue ticket

Ergotamine Withdrawal


Presentation

  • In addition, many patients presenting with neurological disorders are found to be suffering not from primary diseases of the nervous system but rather from neurological compli cations of systemic disease.[books.google.com]
  • The latest and the best classes on TabletWise.com 5683 Views • 25 Saves • Beginner • 14 Lessons • 41:39 • Presentation Skills to Expand Your Career 673 Views • 4 Saves • All-Levels • 9 Lessons • 1:42:48 • Learn to paint with confidence & greatly improve[tabletwise.com]
  • Michael Clinical Neuropharmacology: June 1986 Review: PDF Only Abstract Summary: Based on our clinical experience and the data reviewed and presented in this report, we propose that a state of physical dependency to ergotamine tartrate exists.[journals.lww.com]
  • […] require withdrawal of such food from the market, where the food is found unsafe because of the level of ergot alkaloids, despite its compliance with the maximum level on ergot sclerotia. en This relationship is not absolute, as ergot alkaloids can also be present[hr.glosbe.com]
  • Ergotamine should be used with care when anaemia is present. There have been a few reports of patients on ergotamine developing retroperitoneal and/or pleuropulmonary fibrosis.[medicines.org.uk]
Epilepsy
  • Examples of these new treatments include the control of cerebral edema, new antibiotics for infections of the nervous system, drug level measurements for the evaluation of the adequacy of treatment of epilepsy and advances in neurosurgical technique.[books.google.com]
  • Side effects are mostly dose-related, and are less troublesome when topiramate is used for migraine than for epilepsy, as the doses are typically lower (100 mg per day compared with 200–400 mg per day).[mja.com.au]
Malaise
  • It is known to produce malaise, nausea and, above all, increased frequency of headache (Lippman 1955; Saper 1967; Rose and Wilkinson 1976), and subsequently a predictable daily or near daily headache syndrome (Mathew et al. 1982).[link.springer.com]
  • […] phonophobia) 30-60 min; complete relief w/in 4 hours Sumatriptan intranasal onset 15-20 min; complete relief w/in 2 hours adverse effects of sumatriptan chest symptoms (heavy arms, pressure in chest) angina (coronary vasospasm) teratogenesis vertigo, malaise[quizlet.com]
Alopecia
  • Divalproex 600 to 2,000 mg daily Nausea, somnolence, dizziness, insomnia, anorexia, weakness, thrombocytopenia, alopecia, weight gain In an open-label study, 28 nine of 15 patients experienced complete disappearance of pain, and two others markedly improved[aafp.org]
  • Side effects of estrogens are many, and include: breakthrough bleeding, dysmenorrhea, amenorrhea, menstrual flow changes, endometrial hyperplasia, vaginal candidiasis, nausea, abdominal cramps, colitis or cholestatic jaundice, alopecia or hives, hirsutism[chicagoheadacheclinic.com]
Back Pain
  • الصفحة 18 - There are other situations such as addiction, stroke rehabilitation, headache, menstrual cramps, tennis elbow, fibromyalgia, myofascial pain, osteoarthritis, low back pain, carpal tunnel syndrome, and asthma, in which acupuncture may be useful[books.google.com]
  • People with migraine or tension-type headaches who use painkillers frequently for other problems such as back pain may also develop MOH.[headacheaustralia.org.au]
  • It is generally not seen in people taking painkillers for reasons other than headaches, such as arthritis or back pain.[migrainetrust.org]
  • pain, little or no urine.Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, vision changes, confusion, slurred speech.A very serious allergic reaction to this drug is unlikely, but seek immediate medical[medicinenet.com]
Low Back Pain
  • الصفحة 18 - There are other situations such as addiction, stroke rehabilitation, headache, menstrual cramps, tennis elbow, fibromyalgia, myofascial pain, osteoarthritis, low back pain, carpal tunnel syndrome, and asthma, in which acupuncture may be useful[books.google.com]
  • Analgesic overuse among subjects with headache, neck, and low-back pain. Neurology. 2004;62(9):1540–1544. 14. Zwart JA, Dyb G, Hagen K, et al. Analgesic use: a predictor of chronic pain and medication overuse headache.[dovepress.com]
Muscle Cramp
  • Musculoskeletal: muscle cramps, joint pains. Neurological disorders: Dysaesthesia, paraesthesiae, formication, tremor, convulsions, headache, extrapyramidal effects.[medicines.org.uk]
  • Symptoms of ergotism include angina, asthenia, chest pain (unspecified), coronary vasospasm, muscle cramps (claudication), myalgia, paresthesias, and palpitations or changes in heart rate (e.g., sinus bradycardia or sinus tachycardia).[pdr.net]
Dysmenorrhea
  • Side effects of estrogens are many, and include: breakthrough bleeding, dysmenorrhea, amenorrhea, menstrual flow changes, endometrial hyperplasia, vaginal candidiasis, nausea, abdominal cramps, colitis or cholestatic jaundice, alopecia or hives, hirsutism[chicagoheadacheclinic.com]
Stroke
  • الصفحة 18 - There are other situations such as addiction, stroke rehabilitation, headache, menstrual cramps, tennis elbow, fibromyalgia, myofascial pain, osteoarthritis, low back pain, carpal tunnel syndrome, and asthma, in which acupuncture may be useful[books.google.com]
  • Uses How To Use Side Effects Precautions Drug Interactions Overdose Notes Missed Dose Storage WARNING: This medication has rarely caused a very serious lack of blood flow to the hands and feet (peripheral ischemia ) or to the brain, which could cause a stroke[medicinenet.com]
  • Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council[richtlijnendatabase.nl]
  • National Institute of Neurological Disorders and Stroke. . Accessed Oct. 29, 2018. Daroff RB, et al. Headache and other craniofacial pain. In: Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. .[mayoclinic.org]
  • Lindboe CF, Dahl T, Rostad B "Fatal stroke in migraine: a case report with autopsy findings." Cephalalgia 9 (1989): 277-80 11. Stillman AE, Weinberg M, Mast WC, Palpant S "Ischemic bowel disease attributable to ergot."[drugs.com]
Recurrent Headache
  • Nonpharmacological approaches in the management of recurrent headache disorders and their comparison and combination with pharmacotherapy. Clinical Psychology Review, 6, 543-57 1. Gawel, M., Burkitt, M., & Rose, FC (1979). ‏[books.google.com]
  • In 1955, Lippmann first characterized recurrent headaches resulting from prolonged ergotamine use ( Lippmann 1955 ).[medlink.com]
  • Concurrently, prophylaxis is initiated to suppress the recurrent headaches expected throughout the remaining cluster period; prophylaxis is continued for the expected duration of the cluster period and then tapered off.[aafp.org]
  • Behavioral management of the trig-gers of recurrent headache: a randomized controlled trial. Behav Res Ther. 2014;61:1-11. 14 - GRADE_NL. Toepassen GRADE in Nederland. 2012. 15 - Rabbie R, Derry S, Moore RA.[richtlijnendatabase.nl]
Somnolence
  • Side effects include drowsiness, dizziness, somnolence and an unusual problem with word-finding, paraesthesiae in hands and feet, and reduced appetite and weight loss.[mja.com.au]
  • Diarrhea Frequency not reported : Retroperitoneal fibrosis [ Ref ] Nervous system Common (1% to 10%): Dizziness Uncommon (0.1% to 1%): Paraesthesia, hypoaesthesia Rare (less than 0.1%): Cerebral ischemia, drowsiness Frequency not reported : Weakness, somnolence[drugs.com]
  • Cependant, mirnite 7.5 price les conducteurs de véhicules ou utilisateurs de machines doivent être avertis que les traitements antihypertenseurs peuvent parfois provoquer des étourdissements ou une somnolence, en particulier en début de traitement ou[steadfastep.com]
  • Divalproex 600 to 2,000 mg daily Nausea, somnolence, dizziness, insomnia, anorexia, weakness, thrombocytopenia, alopecia, weight gain In an open-label study, 28 nine of 15 patients experienced complete disappearance of pain, and two others markedly improved[aafp.org]
Neurologic Manifestation
  • manifestations such as confusion, psychosis, convulsions, drowsiness, hemiplegia and peripheral neuropathy (Hokkanen et al. 1978; Horton and Peters 1982).[link.springer.com]
Peripheral Neuropathy

Treatment

  • Twenty years ago neurology was justly criticised for its preoccupation with diagnosis and classification, and for the relative paucity of treatments then available. All this has now changed, and neurology has become a treatment-oriented specialty.[books.google.com]
  • The fact is that differential diagnosis and treatment of recurrent and chron ic headaches represents a broad field that cuts across many disciplines.[books.google.de]

Prognosis

  • The prognosis is best when Lyme disease is diagnosed and treated early and worsens when diagnosis and treatment is delayed. The significance of these spontaneous reports in terms of risk to the fetus is not known.[saopf.org.za]
  • Prognosis Early intervention is important because the long-term prognosis depends on the duration of medication overuse. The headache usually starts to improve within two weeks and the improvement then continues for weeks or even months.[patient.info]
  • Medication overuse headache: Treatment and prognosis. . Accessed Oct. 30, 2018. Chiang CC, et al. Treatment of medication-overuse headache: A systematic review. Cephalgia. 2016;36:371. Cevoli S, et al.[mayoclinic.org]
  • Dependence scores predict prognosis of medication overuse headache: a prospective cohort from the Akershus study of chronic headache. Pain. 2012;153(3):682–686. 123. Fuh JL, Wang SJ, Lu SR, Juang KD.[dovepress.com]

Etiology

  • Etiology Positron emission tomographic (PET) scanning and functional magnetic resonance imaging are helping to clarify the poorly understood etiology of cluster headache.[aafp.org]
  • The role of tyramine in the etiology of migraine and related studies on the cerebral and intracerebral circulations. Headache 8:84-97. Hansen, H.J. and V.M. Drewes (1970). The nitroglycerine ointment test-a double-blind examination.[ihs-klassifikation.de]
  • Comorbidity of migraine and depression: investigating potential etiology and prognosis. Neurology. 2003;60(8):1308-12. 144 - Hung CI, Wang SJ, Yang CH, Liu CY.[richtlijnendatabase.nl]

Epidemiology

  • Epidemiology of headache. Cephalalgia. 2001;21(7):774-7. 184 - Schwartz BS, Stewart WF, Simon D, Lipton RB. Epidemiology of tension-type headache. JAMA. 1998;279(5):381-3. 185 - Rasmussen BK, Jensen R, Olesen J.[richtlijnendatabase.nl]
  • Epidemiology of chronic daily headache in the general population. Headache. 1998;39(3):190–196. 9. Headache Classification Committee of the International Headache Society.[dovepress.com]
  • Epidemiology Lifetime population prevalence is estimated at 1-2%. [ 9 ] About 20% of patients with chronic headaches and most with daily headaches have analgesic rebound headaches. [ 10 , 11 ] Low doses daily carry greater risk than larger doses taken[patient.info]
  • Clinical and epidemiological observations on drug abuse in headache patients. In Drug-Induced Headache, (H.C. Diener and M. Wilkinson, eds.) pp. 20-28. Springer-Verlag, Berlin. Nicolodi, M., P.L. DelBianco, and F. Sicuteri (1997).[ihs-klassifikation.de]
Sex distribution
Age distribution

Pathophysiology

  • Despite intensive research in numerous and very disparate medical disciplines there are still no generally accepted pathophysiologic concepts for many headache syndromes.[books.google.de]
  • Medication-overuse headache: Risk factors, pathophysiology and management. Nature Reviews — Neurology. 2016;12:575. Micieli A. Medication-overuse headache. CMAJ. 2018;190:E296. De Goffau MJ, et al.[mayoclinic.org]
  • Pathophysiology of medication overuse headache: insights and hypotheses from preclinical studies. Cephalalgia. 2011;31(7):851–860. 92. Bongsebandhu-phubhakdi S, Srikiatkhachorn A.[dovepress.com]
  • Calcitonin gene-related peptide (CGRP)-induced headache (this substance is a vasodilator produced by the body and implicated in the pathophysiology of migraine. [ 3 ] Therapeutic non-analgesic medications: headache has been reported after use of a number[patient.info]
  • Clinical features, pathophysiology, and treatment of medication-overuse headache. Lancet Neurol. 2010;9(4):391-401. 11 - Neurologie NVv.[richtlijnendatabase.nl]

Prevention

  • In low doses, I use tamoxifen for the prevention of menstrual migraine. Tamoxifen is one of the more effective menstrual migraine prevention medications.[chicagoheadacheclinic.com]
  • When helpful, it can be useful for controlling pain while starting and building up a preventative medication, particularly as preventatives may take a few months to be fully effective.[migrainetrust.org]
  • […] vasoconstriction and reduces the amplitude of pulsations dihydroergotamine side effects diarrhea but no N/V, dependence, or peripheral vasoconstriction first line for preventative migraines beta blockers (propranolol) drugs for prevention of migraines[quizlet.com]
  • Medication overuse headache Preventing medication overuse is the primary measure for preventing medication overuse headache, the most common type of daily headache.[sydneynorthneurology.com.au]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!