Edit concept Question Editor Create issue ticket

Erythroderma Desquamativum

Leiner Disease


  • It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person. Disclaimer: Whonamedit? does not give medical advice.[whonamedit.com]
  • This is especially present on the scalp and other oily parts of the body, such as the face and back. On the scalp, seborrheic dermatitis includes red skin, scaly patches, and recurring dandruff. It is also known as “cradle cap.”[diseaseinfosearch.org]
  • Obtain thorough guidance on clinical presentation and therapy for a full range of common and rare skin diseases.[books.google.com]
  • Synonym: ichthyosiform erythroderma, ichthyosis spinosa, keratoma malignum. (05 Mar 2000) ichthyosiform erythroderma, congenital Designation for several severe forms of ichthyosis, present at birth, that are characterised by hyperkeratotic scaling.[kmle.co.kr]
Severe Pain
  • A condition caused by continuous infusion therapy and resulting in a tingling sensation of the palms and soles, progressing to severe pain and tenderness with erythema and edema.[definithing.com]
Failure to Thrive
  • […] of Infancy 53 Classifications: MalaCards based summary : Erythroderma Desquamativa of Leiner, is also known as generalized erythroderma, diarrhea, and failure to thrive .[malacards.org]
  • From Wikidata Jump to navigation Jump to search disease Erythroderma desquamativum Generalized erythroderma, diarrhea, and failure to thrive Erythroderma desquamativa of Leiner Erythroderma Desquamativum of Infancy Leiner disease Leiner-Moussous Desquamative[wikidata.org]
  • Symptoms include severe seborrheic dermatitis of the scalp, severe diarrhea, recurrent local and systemic infection, central nervous system problems, and failure to thrive.[en.wikipedia.org]
  • Synonyms Generalized erythroderma, diarrhea, and failure to thrive Erythroderma Desquamativum of Infancy Leiner-Moussous Desquamative Erythroderma Overview No overview is available at this time. Please check back for future updates.[rarediseases.org]
Scaly Rash
  • The condition usually starts off as a scaly rash on the scalp, face or napkin area. Very rapidly it spreads to other parts of the body. The affected area is bright red and may look swollen. Infants appear uncomfortable but do not itch.[dermnetnz.org]
  • . — Gonorrhoea with chancres and warts ; small blisters on orifice of urethra and inner surface of prepuce, forming chancre-like ulcers... ‏ الصفحة 450 - A young man came to me with a bubo in the left groin.[books.google.com]
  • A sedative antihistamine may be a useful adjunct for pruritic patients, since it helps patients to sleep at night, thus limiting nocturnal scratching and excoriations.[dict.eudic.net]
  • A condition caused by continuous infusion therapy and resulting in a tingling sensation of the palms and soles, progressing to severe pain and tenderness with erythema and edema.[definithing.com]
Onset in Infancy
  • Severe, diffuse seborrheic dermatitis, recurrent infections (usually gram-negative), severe diarrhea, and muscle wasting; onset in infancy. Familial form exists.[insidesurgery.com]


  • Diagnosis - Erythroderma desquamativa of Leiner The routine diagnostic workup should include a CBC, sedimentation rate, urinalysis, urine culture, chemistry panel, thyroid profile, sweat test, stool for quantitative fat, chest x-ray, and an EKG.[checkorphan.org]
  • Initial diagnostic workup is included in Table 2 . Figure 5 Algorithm for diagnosis of the erythrodermic infant.[dovepress.com]
Neisseria Gonorrhoeae
  • These patients are at high risk for recurrent infection with Neisseria gonorrhoeae or Neisseria meningitidis. Severe pyogenic infections and sepsis occur in children and neonates who have a deficiency of a MAC component.[emedicine.medscape.com]


  • An easy method of treatment of erythroderma desquamativum Archives Francaises de Pediatrie 17: 516-518 1960 (PDF emailed within 1 workday: 29.90) Accession: 048229865 Download citation: RIS BibTeX Text PMID: 13743967 Treatment of Moussous' erythroderma[eurekamag.com]
  • He had been disappointed in that he had not obtained relief from the treatment used. His bones ached, his tongue was loaded, and his breath smelled badly.[books.google.com]
  • Broaden your knowledge with updated information on serological diagnosis of pemphigus, TNF-I for hidradenitis suppurativa, the use of immunosuppressives for atopic dermatitis, excimer laser for the treatment of vitiligo and much more.[books.google.com]
  • What treatment is available? Initially affected babies may need to be hospitalised to manage fluid and heat loss. Bland emollients may be used to treat the rash . Providing adequate nutrition is also an essential part of treatment.[dermnetnz.org]
  • Treatment The treatment is dependent on the cause. Topical steroids are the primary category of medications used to treat exfoliative dermatitis (ED).[dict.eudic.net]


  • Prognosis - Erythroderma desquamativa of Leiner Not supplied.[checkorphan.org]
  • The prognosis is very good unless proper intensive care and skin care are not provided. The disease is both a familial and a nonfamilial form.[dermaamin.com]
  • Prognosis of erythroderma depends on the underlying disease process. If the cause can be removed or corrected, prognosis is generally good.[dermnetnz.org]
  • Wilson HTH: Exfoliative dermatitis: Its etiology and prognosis. Arch Dermatol 1954;69:577–588.[karger.com]
  • Prognosis and treatment In the study done by Pruszkowski et al , the prognosis was poor with a mortality of 16%. [4] Patients died either due to complications arising from their erythroderma or their underlying disease at a mean age of 7 months.[e-ijd.org]


  • Other drugs specifically indicated for management of underlying etiology of exfoliative dermatitis may be necessary.[dict.eudic.net]
  • Anemia * Diarrhea * Failure to thrive * Reddish skin rash * Thickened skin rash * Spreading rash * Peeling rash * Scaling rash * Itching Causes - Erythroderma desquamativa of Leiner o Psychosocial (non-organic) –Insufficient caloric intake –Most common etiology[checkorphan.org]
  • Erythroderma (from the Greek. erythros red and derma - skin) - a collective term that refers to a group of skin diseases of different etiology and pathogenesis.[medicalency.com]
  • […] are rarer etiologies, but important to recognize early to prevent harmful sequelae.[dovepress.com]
  • The etiology of seborrheic dermatitis is not exactly known. It is considered as an inborn error of seborrheic diathesis.[drmhijazy.com]


  • […] skin diseases, skin appendage diseases, pigmentary diseases, genetic diseases, nutritional and metabolic disorders, tumors, sexually transmitted diseases, AIDS, traditional medicine, integrated Chinese and Western medicine, evidence-based medicine, epidemiology[journalseek.net]
  • EPIDEMIOLOGY Erythroderma is a rare condition. The annual incidence has been estimated to be approximately 1 per 100,000 in the adult population [ 1 ].[uptodate.com]
  • This report defines the prevalence of genital colonization in a large population of women, characterizes the women with S. aureus, and describes epidemiologic features of genital carriage. ‎ Página 50 - Lautenschlager S, Eichmann A.[books.google.es]
  • License: CC BY-SA 3.0 Definition and Epidemiology of Seborrhoeic Dermatitis Seborrhoeic dermatitis is a chronic papulosquamous dermatosis characterised by scaling and poorly defined erythematous patches.[lecturio.com]
  • EPIDEMIOLOGY • Bimodal Age Incidence 0-3 Months of life 4th – 7th Decade of life • Common in HIV/AIDS & PARKINSONISM • Men Women • 03 – 05 % Prevalence 6.[slideshare.net]
Sex distribution
Age distribution


  • History The classification of exfoliative dermatitis into Wilson-Brocq (chronic relapsing), Hebra or pityriasis rubra (progressive), and Savill (self-limited) types may have had historical value, but it currently lacks pathophysiologic or clinical utility[dict.eudic.net]
  • Erythrodermic psoriasis: pathophysiology and current treatment perspectives - Dove Medical Press 2 years ago dovepress.com Abstract: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis vulgaris, with an estimated prevalence of 1%–2.25%[wikinow.co]
  • Psoriasis pathophysiology: Current conceps of pathogenesis. Ann Rheum Dis. 2005; 64(Supple. 2)30-6. Rosenbach M, Hsu S, Korman N. Treatment of erythrodermic psoriasis: from the medical board of the National Psoriasis Foundation.[revistamedicahjca.med.ec]
  • Pathophysiology of Seborrhoeic Dermatitis The exact pathophysiology behind seborrhoeic dermatitis remains unknown with a number of theories propounded. Here, we discuss the most popular ones.[lecturio.com]
  • Pathophysiology The complement cascade consists of 3 separate pathways that converge in a final common pathway.[emedicine.medscape.com]


  • Hospitalization for the diseased person is suggested because of the controlled environment because it may prevent nutritional deficiencies and skin infections.[en.wikipedia.org]
  • […] tubular acidosis –Chronic urinary tract infections –Chronic renal insufficiency * Syndromes –Down syndrome –Turner syndrome –Russell-Silver dwarfism –Fetal alcohol syndrome * Anatomic –Cleft lip/palate –Malrotation –Pyloric stenosis * Lead poisoning Prevention[checkorphan.org]
  • Propoxyphene-containing products may be taken with food to reduce or prevent...[mottchildren.org]
  • Thus, the role of new and innovative investigations related to skin care, skin health, various cutaneous diseases and their preventive or treatment strategies and the need for inaugurating this new journal is self-evident.[wjgnet.com]
  • (PDQ ): Prevention - Health Professional Information [NCI] Endometrial Cancer Prevention (PDQ ): Prevention - Patient Information [NCI] Endometrial Cancer Screening (PDQ ): Screening - Health Professional Information [NCI] Endometrial Cancer Screening[healthmedicinet.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!