Severe, diffuse seborrheic dermatitis, recurrent infections (usually gram-negative), severe diarrhea, and muscle wasting; onset in infancy. Familial form exists. [insidesurgery.com]

[erythro G. derma, skin] bullous congenital… … Medical dictionary Leiner disease — a disorder of infancy characterized principally by generalized seborrhealike dermatitis and erythroderma, intractable, severe diarrhea, recurrent infections, and failure [medicine.academic.ru]

The individual will feel as if they are getting sick all the time or may have recurrent infections. The protein that is lacking usually helps fight inflammation (swelling) and infection of the body. [diseaseinfosearch.org]

Complement factor I deficiency in a family with recurrent infections. Immunopharmacology. 1997 Dec. 38(1-2):207-13. [Medline]. Lutz HU. [emedicine.medscape.com]

A condition caused by continuous infusion therapy and resulting in a tingling sensation of the palms and soles, progressing to severe pain and tenderness with erythema and edema. [definithing.com]

[…] of Infancy 53 Classifications: MalaCards based summary : Erythroderma Desquamativa of Leiner, is also known as generalized erythroderma, diarrhea, and failure to thrive. [malacards.org]

From Wikidata Jump to navigation Jump to search disease Erythroderma desquamativum Generalized erythroderma, diarrhea, and failure to thrive Erythroderma desquamativa of Leiner Erythroderma Desquamativum of Infancy Leiner disease Leiner-Moussous Desquamative [wikidata.org]

Synonyms Generalized erythroderma, diarrhea, and failure to thrive Erythroderma Desquamativum of Infancy Leiner-Moussous Desquamative Erythroderma Overview No overview is available at this time. Please check back for future updates. [rarediseases.org]

Additional symptoms include chronic diarrhea and the failure to gain weight at the expected rate (failure to thrive). The exact cause of erythroderma desquamativa of Leiner is unknown. [hekimce.com]

Other symptoms also include scaling on the trunk and limbs, red patches of skin on parts of the body that bend, fevers, reduced blood protein levels, thick red skin patches, peeling of the skin, itching, corneal ulcers. wasting of the lymph nodes, underdeveloped [en.wikipedia.org]

Longstanding erythroderma may result in pigmentary changes (brown and/or white skin patches). How is erythroderma diagnosed? Blood count may show anaemia, white cell count abnormalities, and eosinophilia. [dermnetnz.org]

— Gonorrhoea with chancres and warts ; small blisters on orifice of urethra and inner surface of prepuce, forming chancre-like ulcers... ‏ الصفحة 450 - A young man came to me with a bubo in the left groin. [books.google.com]

These patients are at high risk for recurrent infection with Neisseria gonorrhoeae or Neisseria meningitidis. Severe pyogenic infections and sepsis occur in children and neonates who have a deficiency of a MAC component. [emedicine.medscape.com]