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Esophageal Leiomyoma

Esophagus Leiomyoma


Presentation

  • Data analyzed included demographic information, presenting symptoms, tumor location, tumor characteristics and histology, diagnostic procedures, and treatment modalities/outcomes.[ncbi.nlm.nih.gov]
  • We present the first reported robotic-assisted thoracoscopic resection of two patients with esophageal leiomyoma using the daVinci Surgical System. Operative technique and technical considerations are presented.[ncbi.nlm.nih.gov]
  • We present our experiences of enucleation of these tumors using thoracoscopic approach. A retrospective review of 40 patients who underwent enucleation of esophageal leiomyoma from 1997 to 2007 in our institute was conducted.[ncbi.nlm.nih.gov]
  • Abstract A 25-year-old woman presented with a giant leiomyoma in the lower third of the esophagus. She had no digestive symptoms, although there was a severe esophageal dilation.[ncbi.nlm.nih.gov]
  • A case simulating esophageal leiomyoma is presented. As in most earlier cases, the diagnosis was established only at thoracotomy. As splenosis is asymptomatic and may have some beneficial immunologic effects, surgical removal is inadvisable.[ncbi.nlm.nih.gov]
Clubbed Finger
  • Abstract The authors report the case study of a 13-year-old girl, suffering from epigastric pain related to an important infectious syndrome and from marked hypertrophic pneumosteopathy (clubbed fingers, diffuse cortical hyperostosis).[ncbi.nlm.nih.gov]
Painful Cough
  • The clinical presentation would often depend on the size of a tumor: small tumors ( large tumors: may cause dysphagia, regurgitation, esophageal obstruction, chest pain, cough, or bleeding (rare) Like other leiomyomas, they comprise of smooth muscle overgrowth[radiopaedia.org]
Flushing
  • Japan), and ERBE VIO Model 300D electrosurgical equipment (Tübingen, Germany) used in the coagulation spray mode (2 to 50 W endocut effect) for the incision and tunnel creation; the tumor was resected with a 3 to 40 W endocut effect, using a BT 2.0 flush[revistagastroenterologiamexico.org]
Neuralgia
  • Paradoxically, incision pain after surgery (thoracic neuralgia) was found to be higher in the minimally invasive approach group.[ncbi.nlm.nih.gov]
  • Clinical case We present the case of a 58-year-old man, without toxic habits and a medical history of malaria, trigeminal neuralgia, total thyroidectomy, and parathyroid resection for papillary cancer, hypothyroidism, and postoperative hypoparathyroidism[oatext.com]

Workup

  • Because malignant transformation in leiomyomas is rare, some authors recommend regular follow-up with barium swallow and endoscopy for asymptomatic patients with lesions smaller than 5 cm and when the preoperative workup has excluded malignancy ( 7, 13[jtd.amegroups.com]
Atelectasis
  • The superiority of the thoracoscopic approach compared to thoracotomy is that it is associated with less postoperative pain, atelectasis, and pleural effusion, and its minimal surgical invasion seems to be suitable for surgery of benign esophageal submucosal[karger.com]

Treatment

  • BACKGROUND AND AIM: To investigate the clinical value of endoscopic ultrasonography (EUS) with miniature ultrasonic probes (MUP) for the diagnosis and treatment of esophageal leiomyoma.[ncbi.nlm.nih.gov]
  • Furthermore, they are related to rupture of the esophageal mucosa during surgical treatment.[ncbi.nlm.nih.gov]
  • The main outcomes included the demographic and morphological characteristics, symptoms, comparisons of diagnosis and treatment methods, adverse events, and prognosis.[ncbi.nlm.nih.gov]
  • Although enucleation via thoracotomy has been considered standard treatment, minimally invasive surgery is increasingly used for the treatment of this disease.[ncbi.nlm.nih.gov]
  • OBJECTIVE: To study the characteristics of diagnosis and surgical treatment of esophageal leiomyoma.[ncbi.nlm.nih.gov]

Prognosis

  • The main outcomes included the demographic and morphological characteristics, symptoms, comparisons of diagnosis and treatment methods, adverse events, and prognosis.[ncbi.nlm.nih.gov]
  • The overall prognosis of these benign tumors is excellent.[radiopaedia.org]
  • Consultations Thoracic surgeon Prognosis Following complete surgical resection, no recurrence has ever been reported.[drminkim.com]
  • Seite 79 - T et al (1995) Mortality and morbidity rates, postoperative course, quality of life, and prognosis after extended radical lymphadenectomy for esophageal cancer, Comparison of threefield lymphadenectomy with two-field lymphadenectomy.[books.google.de]
  • Prognosis Following complete surgical resection, no recurrence has ever been reported. Jiang W, Rice TW, Goldblum JR. Esophageal leiomyoma: experience from a single institution. Dis Esophagus. 2013 Feb-Mar. 26(2):167-74. [Medline].[emedicine.medscape.com]

Etiology

  • Etiology Diffuse leiomyomatosis with Alport syndrome is due to a deletion involving the 5' terminal region of both COL4A5 and COL4A6 (as such, it forms a contiguous gene syndrome).[orpha.net]

Epidemiology

  • Epidemiological data (gender, age), tumor location, tumor size, procedure-related parameters, complications, length of stay and cost were compared between STER and VATS.[ncbi.nlm.nih.gov]
  • Epidemiological data, presenting symptoms, diagnostic investigations, tumor location, histopathological findings, and safety and efficacy of surgical resection were analyzed.[ncbi.nlm.nih.gov]
  • Epidemiology Frequency International Esophageal leiomyomas comprise less than 0.6% of all esophageal neoplasms, both in the United States and worldwide.[drminkim.com]
  • Summary Epidemiology Prevalence is estimated at 1 per million. Clinical description Alport syndrome (AS) is defined by glomerular nephropathy with hematuria, progressing to end-stage renal disease, associated with sensorineural deafness.[orpha.net]
  • Among the 22 patients (78.6%) for whom follow-up information was available, no leiomyoma-related adverse events were found. [1] Epidemiology United States and international data Esophageal leiomyomas comprise less than 0.6% of all esophageal neoplasms[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Specific sections deal with Physiology and Pathophysiology, Clinical Presentation of Disease, Clinical Manifestations and Management (discussing the Mouth and Esophagus, The Stomach and Duodenum, The Intestine, and The Pancreas), Diagnosis of Gastrointestinal[books.google.de]
  • Unlike others on this topic, this text demonstrates how the endoscope incorporates pathophysiology, diagnostic, and treatment modalities into endoscopic practice.[books.google.de]
  • Thus, leiomyomas are the most common benign tumors of the esophagus. [1] Pathophysiology Leiomyomas represent a hyperproliferation of interlacing bundles of smooth muscle cells that are well-demarcated by adjacent tissue or by a smooth connective tissue[drminkim.com]

Prevention

  • The use of the balloon dilator facilitates separation of the tumor from both the mucosal and muscular layers of the esophagus, and may help to prevent perforation.[ncbi.nlm.nih.gov]
  • The advantages of thoracoscopic surgery for esophageal leiomyoma include its safety and long-term prevention of recurrence.[ncbi.nlm.nih.gov]
  • After enucleation in selected patients, anti-reflux procedure should be carried out in order to protect the area of surgical resection and prevent complications from weakening the lower esophageal sphincter, as well as to resolve reflux symptoms.[ncbi.nlm.nih.gov]
  • Reapproximation of the muscle layers was performed after tumor enucleation to prevent the development of a pseudodiverticulum. A Nissen or Toupet fundoplication was added for patients undergoing laparoscopic enucleation of the leiomyoma.[ncbi.nlm.nih.gov]
  • Special chapters, such as the Designing Clinical Research in Gastrointestinal Endoscopy, The Prevention of Infection Following Gastrointestinal Endoscopy, Complications of Peptic Ulcer Disease, and Credentialing for Gastrointestinal Endoscopy, help make[books.google.de]

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