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Estrogen Resistance Syndrome


Presentation

  • Glucose intolerance, hyperinsulinemia and lipid abnormalities may also be present.[uniprot.org]
  • He is Executive Advisory Editor of Bone Research (2013-present).[books.google.com]
  • Milder cases of insulin resistance may present with normal fasting concentrations of insulin and glucose.[aafp.org]
  • More often, CAIS individuals present to a physician during puberty when they fail to menstruate.[britannica.com]
  • And again, the reason it presents itself in so many different ways is because PCOS is fundamentally tied to the hormones.[pcos.com]
Tall Stature
  • stature ( E34.4 ) increased secretion from endocrine pancreas of growth hormone-releasing hormone ( E16.8 ) E22.1 Hyperprolactinaemia Use additional external cause code (Chapter XX), if desired, to identify drug, if drug-induced.[apps.who.int]
  • By the age of puberty, she developed progressive signs of virilization with no signs of estrogen action such as hypergonadotropic hypogonadism, polycystic ovaries, and tall stature.[dovepress.com]

Treatment

  • Explore important issues in infertility, such as egg freezing, cancer treatment, and preimplantation genetic diagnosis.[books.google.com]
  • HRT has been investigated as a possible treatment to improve insulin action and negate the consequences of insulin resistance.[livestrong.com]
  • It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice .[uniprot.org]
  • Clinical efficacy of lower dose flutamide 125 mg/day in the treatment of hirsutism. J Endocrinol Invest 22: 165, 1999. PubMed CrossRef Google Scholar 21. Vigersky RA, Mehlman I, Glass AR, Smith CE. Treatment of hirsute women with cimetidine.[link.springer.com]

Prognosis

  • […] growth factor I /Smad signaling and associates with favorable breast cancer disease outcomes. ( 25499443 ) Guo J....Lebrun J.J. 2014 8 Expression of breast cancer anti-estrogen resistance 1 in relation to vascular endothelial growth factor, p53, and prognosis[malacards.org]
  • Prognosis With treatment, symptoms may improve or go away. Women with polycystic ovary syndrome need to pay strict attention throughout their life to ways they can reduce their risks of heart disease and diabetes.[drugs.com]
  • Surg Today Aug 2015 [Refereed] The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer.[researchmap.jp]

Etiology

  • If you were born with ambiguous genitals and testes, there are a number of possible etiologies, including partial AIS. Testing for partial AIS is more problematic than the complete form.[isna.org]
  • A summary of potential etiologies is found in Table 1 .[glowm.com]
  • The exciting news recently involves understanding the contribution of insulin resistance to the etiology and treatment of PCOS.[arcfertility.com]
  • Epidemiologic studies have suggested that estrogen deficiency plays a role in the etiology of lower urinary tract symptoms—70% of women relate the onset of urinary incontinence to their final menstrual period. 1 Additionally, urogenital symptoms resulting[uspharmacist.com]
  • Verrucous, velvety hyperpigmentation on nape of neck, vulva, axillae, groin, umbilicus, submammary regions; increased skin tags Obesity Increased waist-to-hip ratio (android appearance) Insulin resistance is categorized as type A or type B, depending on the etiology[aafp.org]

Epidemiology

  • & Molecular Epidemiology(2), Japan Epidemiological Association(387), Japan Society of Clinical Oncology(421), American Association for Cancer Research(209), The Japanese Association for Molecular Target Therapy of Cancer(124) Research Grants & Projects[researchmap.jp]
  • European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology . 2011;18(1):86-96. 36.[nebido.com]
  • Additional Contributors Arlan L Rosenbloom, MD Adjunct Distinguished Service Professor Emeritus of Pediatrics, University of Florida College of Medicine; Fellow of the American Academy of Pediatrics; Fellow of the American College of Epidemiology Arlan[emedicine.medscape.com]
  • Epidemiologic studies have suggested that estrogen deficiency plays a role in the etiology of lower urinary tract symptoms—70% of women relate the onset of urinary incontinence to their final menstrual period. 1 Additionally, urogenital symptoms resulting[uspharmacist.com]
  • J Reprod Med 39: 327, 1994 58 Flack J, Sowers J: Epidemiologic and clinical aspects of insulin resistance and hyperinsulinemia.[glowm.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Between the 8th and 10th week of gestation, male gonads begin producing testosterone, dihydrotestosterone, and Müllerian inhibiting factor, which are hormones critical to male development.[britannica.com]
  • Pathophysiology J Obstet Gynaecol Can. 2010 May;32(5):423-5, 426-8. Nat Rev Endocrinol. 2011 Apr;7(4):219-31. N Engl J Med. 2005 Mar 24;352(12):1223-36.[pathophys.org]
  • In addition, testosterone has been shown to reduce β-amyloid accumulation, an important pathophysiologic factor in Alzheimer’s disease (Zhang et al 2004, Rosario and Pike 2008).[lifeextension.com]
  • Hyperandrogenism, insulin resistance, and acanthosis nigricans syndrome: a common endocrinopathy with distinct pathophysiologic features. Am J Obstet Gynecol. 1983;147:90–101. 3. Esperanza LE, Fenske NA.[aafp.org]
  • This review focuses on the clinical features and molecular pathophysiology of AIS and explores the relationship of the molecular defects in the AR gene to their clinical expression.[hormones.gr]

Prevention

  • Understand the latest research in menopause, how to effectively prescribe treatments, and the consideration of using hormones for prevention. A new chapter dedicated to in vitro fertilization keeps you current with today's recent advances.[books.google.com]
  • Prevention There is currently no way for most people to prevent polycystic ovary syndrome.[drugs.com]
  • Hormonal contraceptives are also useful for preventing uterine problems.[courses.washington.edu]
  • Because there is no cure for PCOS, it needs to be managed to prevent further problems. There are many medications to control the symptoms of PCOS. Doctors most commonly prescribe birth control pills for this purpose.[diabetes.org]
  • Preventing long-term problems A healthy lifestyle is important to help prevent the conditions listed above in 'Possible long-term problems of polycystic ovary syndrome (PCOS)'. For example, you should: Eat a healthy diet. Exercise regularly.[patient.info]

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