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Estrogenic Agents

Estrogenic Compounds


Presentation

  • Collection includes both citations and many full-text, downloadable documents from mid-1900s to present. AULIMP - Air University Library Index to Military Periodicals.[dtic.mil]
  • "THE MATERIAL PRESENTED HERE ONLY ENHANCES CLASSROOM TEACHING AND IN NO WAY SHOULD BE CONSTRUED AS REPLACING IT.[people.vcu.edu]
  • All key ERs present throughout the body are also present in synapses of the hippocampus and prefrontal cortex.[ncbi.nlm.nih.gov]
  • In an attempt to present a conceptual model, the literature of the past 30 years on mood and well-being throughout reproductive life is reviewed as it relates to activity of endogenous, bio-identical, and synthetic estrogen in women.[doi.org]
Arm Pain
  • Get medical help right away if you experience: sudden shortness of breath, chest/jaw/left arm pain, unusual sweating, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms[webmd.com]
Suggestibility
  • Our results suggested that up-regulation of BLM expression by E2 and BPA is ER-dependent and may be responsible for repair of DNA damage caused by the genotoxicity of these estrogenic agents.[ncbi.nlm.nih.gov]
  • Additionally, both preclinical and clinical findings suggest that activation of estrogen receptors have an important role in neuroprotective and neurodegenerative processes in the mammalian central nervous system (CNS).[ncbi.nlm.nih.gov]
  • […] further validated by Estrogen Receptor-α (ER-α) and Estrogen Receptor-β (ER-β) competitive binding assays to reveal the high selective affinity of LA-7 towards ER-α at 5.49μM, while LA-10 did not show any binding affinity towards neither ER-α nor ER-β; suggesting[ncbi.nlm.nih.gov]
  • However, further research suggests that the actual pharmacologically active agents are polymers of anethole, such as dianethole and photoanethole.[ncbi.nlm.nih.gov]
  • However, further research suggests that the actual pharmacologically active agents are polymers of anethole, such as dianethole and photoanethole. CITATION: Albert-Puleo M. Fennel and anise as estrogenic agents. J Ethnopharmacol. 1980;2(4):337-344.[aromaticscience.com]
Slurred Speech
  • speech, weakness on one side of the body, sudden vision changes (such as partial/complete blindness).Your healthcare professionals may already be aware of this interaction and may be monitoring you for it.[webmd.com]

Treatment

  • Tamoxifen is also a common chemotherapeutic treatment for ER-positive breast cancer.[cebp.aacrjournals.org]
  • The current Canadian product information for HRT products warns about the risk of ovarian cancer during treatment, especially after 5 years of treatment or more.[canada.ca]
  • The expression of cell-cycle associated genes, cdc6, MCM5, MCM2, Myt1, PCNA and AuroraA were up-regulated by E2 and BPA treatment in MCF-7 cells accompanied by up-regulation of BLM.[ncbi.nlm.nih.gov]
  • Several studies show beneficial effects of estrogen treatment in women with anxiety and depressive symptoms. Recent data indicate that the estrogen receptor (ER) beta appears to be a major mediator of estrogenic effects in depression and anxiety.[ncbi.nlm.nih.gov]
  • A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.[webmd.com]

Prognosis

  • Consequently, estrogen mediated ER signaling plays a critical role in breast cancer diagnosis, prognosis, and treatment. Estrogen Receptors are ligand-triggered transcription factors.[ubir.buffalo.edu]
  • View Article Google Scholar Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL, Liu ET: Breast cancer classification and prognosis based on gene expression profiles from a population-based study.[doi.org]

Etiology

  • Premenstrual disorders: prevalence, etiology and impact. Journal of Reproductive Medicine ; 51(4 Suppl):339-347 Yonkers, K. A., & Casper, R. F. (2018, January 15).[womensmentalhealth.org]
  • Severe maternal virilisation of benign etiology in two successive pregnancies. BJOG 112, 1443–1445 (2005). 26. Scott, R. R. & Miller, W. L. Genetic and clinical features of p450 oxidoreductase deficiency. Horm. Res. 69, 266–275 (2008). 27.[doi.org]
  • Exploring the relationship between negative urgency and dysregulated eating: Etiologic associations and the role of negative affect. Journal of Abnormal Psychology, 122, 433 – 444. doi: 10.1037/a0031250 Google Scholar Crossref Medline Racine, S.[doi.org]
  • Etiology and treatment of hypogonadism in adolescents. Endocrinol Metab Clin North Am. 2009 Dec. 38(4):719-38. [Medline]. Murphy KG. Kisspeptins: regulators of metastasis and the hypothalamic-pituitary-gonadal axis.[emedicine.medscape.com]
  • Because of the diverse etiology of these diseases, the comprehension of the mechanism underlying estrogen beneficial action is puzzling.[nature.com]

Epidemiology

  • […] increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology[books.google.com]
  • Large-scale epidemiological studies have demonstrated that oestrogen replacement therapy leads to approximately 50 per cent reduction of cardiovascular disease in women taking hormones, compared with untreated women.[ncbi.nlm.nih.gov]
  • In addition, the question of the risks from environmental estrogen mimics is a very difficult one, because the biological, epidemiological and exposure issues involved are all extremely complex.[scientificamerican.com]
  • Past epidemiological evidence, however, does worry Dr. Cooper, because some chemical exposures have been associated with early puberty.[nytimes.com]
  • A large body of studies points to a potential beneficial role of estrogens in different brain pathologies, as proved by epidemiological, experimental and animal model data after the natural or surgical ablation of estrogen synthesis.[nature.com]
Sex distribution
Age distribution

Pathophysiology

  • Coverage of pathophysiology and interventions for the pregnant woman, fetus, and newborn for selected abnormal events provides a solid understanding of physiologic adaptations and developmental physiology relating to major body systems and metabolic processes[books.google.com]
  • It is a truly integrated text using large numbers of real clinical cases to introduce the basic biochemistry, physiology and pathophysiology underlying endocrine disorders and also the principles of clinical diagnosis and treatment.[ncbi.nlm.nih.gov]
  • There is increasing evidence that in both men and women extraglandular production of C(18) steroids from C(19) precursors is important in normal physiology as well as in pathophysiologic states.[ncbi.nlm.nih.gov]
  • Jean-François Arnal, Marie-Cécile Valéra, Bernard Payrastre, Francoise Lenfant and Pierre Gourdy, Structure-function relationship of estrogen receptors in cardiovascular pathophysiological models, Thrombosis Research, 130, (S7), (2012). I.J.[doi.org]
  • This issue is even more complex if we consider that hormone positively affects other pathophysiologic processes, such as osteoporosis, atherosclerosis and stroke.[nature.com]

Prevention

  • Some HRT products are also used to prevent weakening of bones (osteoporosis). Selective estrogen receptor modulators (SERMs) (raloxifene, bazedoxifene) are also used for preventing and treating osteoporosis and some symptoms of menopause.[canada.ca]
  • Estrogen therapy (ET) prevents the decrease in verbal memory when administered immediately following the surgical removal of both ovaries in premenopausal women.[ncbi.nlm.nih.gov]
  • Besides being natural body products, estrogens may be administered to i) treat or prevent osteoporosis and ii) in birth control in combination with progesterones We will have more chance to study the birth control aspect when we move to progestins.[people.vcu.edu]
  • Efficacy of estrogens in the prevention of osteoporosis as assessed by densitometry has been demonstrated for conjugated oral estrogens.(ABSTRACT TRUNCATED AT 400 WORDS)[ncbi.nlm.nih.gov]
  • The labeling bears any direct or implied statement that the product screens out ultraviolet sunlight, prevents or treats sunburn, helps prevent wrinkles, or prevents premature aging of the skin, 2.[web.archive.org]

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