Depending on which genes are affected, other symptoms may include: Abnormal nails Abnormal or missing teeth, or fewer than normal number of teeth Cleft lip Decreased skin color (pigment) Large forehead Low nasal bridge Thin, sparse hair Learning disabilities [medlineplus.gov]

Nails Abnormalities in the shape of the nails and it affects both the fingernails and toenails. Different color of the nail, slow growing and brittleness are also present. [healthfoxx.com]

These carrier females are usually asymptomatic or may express a variable phenotype of this condition in view of random inactivation of one of the X-chromosome during early embryogenesis [ 4 ]. [edoj.org.eg]

Ectodermal dysplasia with alopecia, onychodysplasia, hypohidrosis, keratoderma, abnormal teeth and deafness. Indian J Dermatol Venereol Leprol 2007 Nov-Dec;73(6):409–11. [ CrossRef ] [ Pubmed ] Vieira KA, Teixeira MS, Guirado CG, Gavião MB. [ijcasereportsandimages.com]

The lack of teeth or abnormal teeth and the special appearance were reported to be of major concerns. Oral traits of ectodermal dysplasia may be expressed as anodontia or hypodontia, with or without a cleft lip and palate. [pubs.sciepub.com]

Assigned diseases: Back to detailed view In the following you will find the diseases that this support group organisation focuses on: ADULT syndrome AREDYLD syndrome Acrofacial dysostosis, Weyers type Alopecia-contractures-dwarfism-intellectual disability [se-atlas.de]

Fig 1: Diffuse alopecia on the vertex with dry lusterless hair at the margins of the scalp. Fig 2: Sparse eyebrows and eyelashes with ectropion of both eyes. Fig 3: Hypodontia with conical lower incisors. [edoj.org.eg]

Ectodermal dysplasia alopecia preaxial polydactyly 0 *Alopecia *Ectodermal Dysplasia *Polydactyly *Facies. Ectodermal dysplasia adrenal cyst 0 *Adrenal Gland Diseases *Cysts *Ectodermal Dysplasia. [reference.md]

The main findings include: alopecia, onychodysplasia, hypohidrosis, sensorineural deafness, skin with a tan color and hyperkeratosis (involving also plams and soles), unusual facies (with slight auricle and nose abnormalities), pectus excavatum, severe [karger.com]

Clinical differential considerations include: alopecia areata aplasia cutis congenita focal dermal hypoplasia syndrome incontinentia pigmenti Naegeli-Franceschetti-Jadassohn syndrome pachyonychia congenita Promoted articles (advertising) [radiopaedia.org]

The main findings in both children are: hypodontia, abnormally shaped teeth, scalp hypotrichosis, pili annulati, follicular hyperkeratosis on the trunk and limbs, intensified delineation and reticular hyperpigmentation of the nape, and hyperopia; one [ncbi.nlm.nih.gov]

[…] definitionPilodental dysplasia-refractive errors syndrome is a rare ectodermal dysplasia syndrome characterized by dysplastic abnormalities of the hair and teeth (including hypodontia, abnormally shaped teeth, scalp hypotrichosis and pili annulati), follicular hyperkeratosis [malacards.org]

Clinical: Hypodontia; abnormally shaped teeth; scalp hypotrichosis; disorders of pigmentation of the hair; follicular hyperkeratosis on the trunk and limbs; intensified delineation and reticular hyperpigmentation of the skin of the nape; broadening of [esanatos.com]

The main findings include: alopecia, onychodysplasia, hypohidrosis, sensorineural deafness, skin with a tan color and hyperkeratosis (involving also plams and soles), unusual facies (with slight auricle and nose abnormalities), pectus excavatum, severe [karger.com]

The palmer skin biopsy confirmed the absence of sweat and sebaceous glands and revealed orthokeratotic hyperkeratosis and acanthosis of the epidermis. The Starch Iodine test on the back demonstrated lack of sweating. [edoj.org.eg]

The main findings in both children are: hypodontia, abnormally shaped teeth, scalp hypotrichosis, pili annulati, follicular hyperkeratosis on the trunk and limbs, intensified delineation and reticular hyperpigmentation of the nape, and hyperopia; one [ncbi.nlm.nih.gov]

Intensified delineation, reticular hyperpigmentation of the nape and astigmatism have also been reported. There have been no further descriptions in the literature since 1985.Visit the Orphanet disease page for more resources. [malacards.org]

Clinical: Hypodontia; abnormally shaped teeth; scalp hypotrichosis; disorders of pigmentation of the hair; follicular hyperkeratosis on the trunk and limbs; intensified delineation and reticular hyperpigmentation of the skin of the nape; broadening of [esanatos.com]

In the other case described, 5 facial dysmorphy was absent, but skin manifestations were more severe with hemangiomata at birth, hyperpigmentation of the skin, and eczema. [pediatrics.aappublications.org]

The patient had a distinct facies with a prominent forehead, periorbital wrinkling and hyperpigmentation, depressed mid-face, and full everted lips. Only five peg-shaped upper teeth were present. Body hair were sparse. [ijdvl.com]

The main findings in both children are: hypodontia, abnormally shaped teeth, scalp hypotrichosis, pili annulati, follicular hyperkeratosis on the trunk and limbs, intensified delineation and reticular hyperpigmentation of the nape, and hyperopia; one [ncbi.nlm.nih.gov]

hyperkeratosis on the trunk and limbs, and hyperopia. [malacards.org]

Clinical: Hypodontia; abnormally shaped teeth; scalp hypotrichosis; disorders of pigmentation of the hair; follicular hyperkeratosis on the trunk and limbs; intensified delineation and reticular hyperpigmentation of the skin of the nape; broadening of [esanatos.com]

Health problems from this condition may include: Brain damage caused by increased body temperature Seizures caused by high fever ( febrile seizures ) Call for an appointment with your health care provider if your child shows symptoms of this disorder. [medlineplus.gov]

Complications Possible complications include: Febrile seizure due to high fever. Recurrent infections in the upper respiratory tract are common. Inflammation of the scalp that will result to erosion because of Alopecia. Failure in growth development. [healthfoxx.com]

Clinical diagnosis is usually made in infancy or childhood when they present with skin, dental, hair, and nail changes, if undiagnosed early, the child may present with complications like seizures (due to hyperthermia), xerophthalmia, conjunctivitis or [ijcasereportsandimages.com]

The first injection of Thymoglobulin resulted in massive cardiovascular toxicity with collapsus, generalized seizures, and necrosis of the skin of the extremities (feet and hands). [pediatrics.aappublications.org]