Presentation
Summary These tables present data on deaths that occurred before one completed year of life, and which were registered with Births, Deaths and Marriages in 2010. [health.govt.nz]
The diagnosis of PROM is assumed if one of the following is present: Amniotic fluid appears to be escaping from the cervix. Vernix or meconium is visible. [merckmanuals.com]
In some cases, the umbilical cord may also slip out of the birth canal in front of the baby, becoming compressed between the presenting part of the baby (usually the head) and the mother’s vaginal canal. This is known as cord prolapse. [abclawcenters.com]
Infants with TTN and pneumonia or meconium aspiration may have similar clinical presentations. [anestesiarianimazione.com]
All infants presenting with symptoms and signs of ABE should receive immediate exchange transfusion. [pathophys.org]
Entire Body System
- Anemia
If the anemia is severe, treatment can involve a transfusion of red blood cells to the newborn. [americanpregnancy.org]
In addition, premature infants are at higher risk for protracted anemia, because they are born with lower body iron stores. [hawaii.edu]
Premature babies are at risk of blood problems such as anemia and newborn jaundice. Anemia is a common condition in which the body doesn't have enough red blood cells. [mayoclinic.org]
Pallor Anemia Hepatosplenomegaly Extravascular hemolysis occurs in the spleen and liver, which sequesters damaged RBCs. Extramedullary hematopoiesis also occurs in these organs in response to anemia. [pathophys.org]
[…] hemorrhage, or bleeding in the lungs hypoglycemia, or low blood sugar neonatal sepsis, a bacterial blood infection pneumonia, an infection and inflammation of the lungs patent ductus arteriosus, an unclosed hole in the main blood vessel of the heart anemia [healthline.com]
- Weakness
These drugs, though not without some risk, help prevent breathing problems and vein hemorrhages, especially in very small infants with weak systems. [cbsnews.com]
Babies with Intrauterine growth restriction (IUGR) may be born early or full-term; premature babies with IUGR may be very small and physically immature, and full-term babies with IUGR may be physically mature but weak. [childrenshospital.org]
Other symptoms may include: Blue skin color, rapid heart rate, rapid breathing (signs of immature lungs or heart failure) Poor sucking, lethargy, weak cry, seizures (signs of severe low blood sugar) Poor feeding Puffy face Tremors or shaking shortly after [medlineplus.gov]
Both lack mineralocorticoid activity and have relatively weak immunosuppressive activity with short-term use. [acog.org]
- Pallor
Diagnostic findings include jaundice (yellow amniotic fluid, yellow vermix, yellow skin), pallor and hepatosplenomegaly. Kernicterus (bilirubin encephalopathy) is a serious risk and hypoglycaemia is common. [patient.info]
Pallor Anemia Hepatosplenomegaly Extravascular hemolysis occurs in the spleen and liver, which sequesters damaged RBCs. Extramedullary hematopoiesis also occurs in these organs in response to anemia. [pathophys.org]
- Fatigue
When managing an infant with TTN, it is important to observe for signs of clinical deterioration that may suggest other diagnoses and to observe closely for the development of fatigue. [anestesiarianimazione.com]
This may lead to fatigue and respiratory failure in the smallest of infants. [hawaii.edu]
- Developmental Disorder
For live births, information was missing as follows (unweighted n): velamentous insertion, 2; furcate insertion, 2; circummarginate insertion, 6; circumvallate insertion, 6; terminal villous hypoplasia, 2; any developmental disorder, 8; acute chorioamnionitis—placental [journals.plos.org]
Gastrointestinal
- Vomiting
Yet, excessive vomiting should not be brushed off. Lack of food hinders normal fetal growth and has devastating effects on the mother’s health. [babygaga.com]
[…] of newborn P9209Other vomiting of newborn P921Regurgitation and rumination of newborn P922Slow feeding of newborn P923Underfeeding of newborn P924Overfeeding of newborn P925Neonatal difficulty in feeding at breast P928Other feeding problems of newborn [cms.gov]
Continuous gastric feedings via infusion pump have the advantage of preventing vomiting and aspiration and abdominal distention associated with intermittent feedings of larger amounts. [medical-dictionary.thefreedictionary.com]
- Nausea
The same can be said for extreme nausea that affects normal appetite and prevents women from eating anything in the first place. 14 Too Much Weight Gain Or Weight Loss via: http://www.shutterstock.com/video/clip-6616637-stock-footage-angry-girl-upset-with-weight-gain.html [babygaga.com]
Liver, Gall & Pancreas
- Jaundice
Breast milk jaundice : Distinct from breastfeeding jaundice, breast milk jaundice develops in the second week of life, lasts longer than physiologic jaundice, and has no other identifiable cause. [pathophys.org]
[…] due to bruising P581Neonatal jaundice due to bleeding P582Neonatal jaundice due to infection P583Neonatal jaundice due to polycythemia P5841Neonatal jaundice due to drugs or toxins transmitted from mother P5842Neonatal jaundice due to drugs or toxins [cms.gov]
After birth, however, the immature neonatal liver is not capable of handling a high bilirubin load and this can result in severe neonatal jaundice. [patient.info]
If the baby develops significant jaundice, phototherapy may be required for a short period (usually from two to five days) to break down the bilirubin in the skin. [pediatricweb.com]
IDMs are more likely to have: Breathing difficulty due to less mature lungs High red blood cell count (polycythemia) High bilirubin level (newborn jaundice) Chances of miscarriage or stillborn child are higher in women with poorly controlled diabetes. [medlineplus.gov]
- Hepatomegaly
Dark urine Hemolysis resulting in hemoglobin entering urine + increased urobilin from increased amount of bilirubin Nonhemolytic State Jaundice Accumulation of unconjugated bilirubin Ecchymosis/hemorrhage Birthing trauma Ruddy complexion, hepatomegaly [pathophys.org]
Cardiovascular
- Hypotension
The most common heart problems premature babies experience are patent ductus arteriosus (PDA) and low blood pressure (hypotension). PDA is a persistent opening between the aorta and pulmonary artery. [mayoclinic.org]
Skin
- Skin Rash
Phototherapy is generally quite safe and complications are very rare, but include burns, retinal damage, thermoregulatory instability, loose stools, dehydration, skin rash and tanning of the skin. [pathophys.org]
Neurologic
- Stroke
Diabetes can contribute to eye disorders and blindness, heart disease, stroke, kidney failure, amputation, and nerve damage. What happens with diabetes and pregnancy? During pregnancy, the placenta supplies a growing fetus with nutrients and water. [stanfordchildrens.org]
Diabetes can contribute to eye disorders and blindness, heart disease, stroke, kidney failure, amputation, and nerve damage. During pregnancy, the placenta supplies a growing fetus with nutrients and water. [chop.edu]
The number of stillbirths occurring globally would place it as the fifth leading cause of death following ischemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections (WHO www.who.int/mediacentre/factsheets/fs310 [journals.plos.org]
Workup
An additional workup for hyperbilirubinemia may include: Blood group and direct Coombs testing in babies who are at risk of Rh or ABO isoimmunization. [pathophys.org]
[…] genetic physician or genetic counselor who will be evaluating your family health history for possible inheritable conditions that would cause hydrops Any other specialists as necessary to address underlying issues or abnormalities uncovered by the overall workup [chw.org]
From a practical viewpoint, when one is confronted with a fetus with IUGR, an etiologic workup is in order, and close fetal surveillance with ultrasonography is necessary. [glowm.com]
Treatment
The only treatment for mirror syndrome is immediate delivery of the baby How do you treat hydrops fetalis? Treatment for hydrops depends on the determined cause, if any. [chw.org]
[…] a complication of the treatment is Figure C 5 The chest x-ray would reveal ground glass opacities and the fundoscopic image depicting a complication of the treatment is Figure B M1 Select Answer to see Preferred Response PREFERRED RESPONSE 5 (M1.PL.75 [medbullets.com]
Treatment For Premature Rupture Of The Membranes (PROM) Treatment for PROM at Term In a term pregnancy where PROM has occurred, allowing labor to occur spontaneously is often the standard of care. [abclawcenters.com]
Treatment should be stopped once total bilirubin is below the treatment threshold. Phototherapy is usually able to decrease bilirubin by 17-34 umol/L within 4-6 hours. [pathophys.org]
Prognosis
It is important to remember the complication of hydrops has a poor prognosis of survival except for those cases that have a definite cause with established fetal treatment. What is my baby's long-term prognosis? Long-term prognosis is guarded. [chw.org]
Prognosis: Prognosis is excellent. Asthma: Schaubel et al looked at neonatal characteristics as risk factors for preschool asthma. [anestesiarianimazione.com]
Conclusion Prenatal diagnosis and ultrasonographic follow-up are needed for the good prognosis of sacrococcygeal teratomas. [oapublishinglondon.com]
The cardiologist must present both the pre and postnatal prognosis of the disease. This information should be objective, based on local as well as other centers’ experience. [revespcardiol.org]
Portal vein thrombosis and portal hypertension may occur in children undergoing exchange transfusion. [ 12 ] One meta-analysis showed a significant link between feto-maternal rhesus incompatibility and schizophrenia. [ 13 ] Prognosis Overall survival [patient.info]
Etiology
(Phototherapy) Treatment depends on the severity of hyperbilirubinemia, its etiology, and the risk of developing serious neurological complications. Phototherapy The mainstay of treatment for hyperbilirubinemia is phototherapy. [pathophys.org]
Obstet Gynecol 105:12–17 PubMed Google Scholar Polzin WJ, Brady K (1998) The etiology of premature rupture of the membranes. [link.springer.com]
The reported racial and ethnic differences in risk factors for and presentations of preterm birth suggest that the etiologies of preterm birth may play a role ( Ananth et al., 2005 ; Reagan and Salsberry, 2005 ). [ncbi.nlm.nih.gov]
The etiology of BPD is problematic and may be due to oxygen, overventilation or underventilation. [en.wikipedia.org]
The etiology is multifactorial. Risk factors include systemic infection, rapid advance of enteral nutrition, decreased intestinal blood flow (relative ischemia), the presence of catheters in umbilical vessels, and poor gut motility. [hawaii.edu]
Epidemiology
Late Preterm and Early Term Births: Epidemiology and Trends; Stillbirth Reduction Efforts and Impact on Early Births; Management of Indicated Early Term and Late Preterm Births; Physiological Underpinnings for Clinical Problems in Moderately Preterm, [books.google.com]
Epidemiology The incidence of haemolytic disease of the newborn (HDN) depends on the proportion of the population who are RhD negative. [patient.info]
Obstet Gynecol Surv 57:299–305 CrossRef PubMed Google Scholar Iyasu S, Saftlas AK, Rowley DL et al (1993) The epidemiology of placenta previa in the United States, 1979 through 1987. [link.springer.com]
Paediatric and perinatal epidemiology. 2013;27(2):145–57. pmid:23374059; PubMed Central PMCID: PMC3564237. View Article PubMed/NCBI Google Scholar 12. Hadlock FP, Harrist RB, Martinez-Poyer J. [journals.plos.org]
Epidemiologically, when a disease has a low prevalence (i.e., perinatal mortality in the USA), the false-negative rate of monitoring tests will be low regardless of the test's sensitivity or specificity. [glowm.com]
Pathophysiology
[…] of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. [books.google.com]
The acquired form is more common, and pathophysiology has not been fully elucidated. [pathophys.org]
Pathophysiology: Noninfectious acute respiratory disease develops in approximately 1% of all newborn infants and results in admission to a critical care unit. TTN is the result of a delay in clearance of fetal lung liquid. [anestesiarianimazione.com]
Pathophysiology [ edit ] The lungs of infants with respiratory distress syndrome are developmentally deficient in a material called surfactant, which helps prevent collapse of the terminal air-spaces (the future site of alveolar development) throughout [en.wikipedia.org]
Neonatology: Pathophysiology and Management of the Newborn, 5th Edition. 1999, Philadelphia: Lippincott Williams & Wilkins Publishers. 2. Behrman RE, Kliegman RM, Jenson HB (eds). [hawaii.edu]
Prevention
Can low birthweight be prevented? Prevention of preterm births is one of the best ways to prevent babies born with low birthweight. Prenatal care is a key factor in preventing preterm births and low birthweight babies. [childrenshospital.org]
Women with diabetes need special care during pregnancy to prevent problems. Controlling blood sugar can prevent many problems. [medlineplus.gov]
Your doctor may be able to suggest additional preventive measures that can help lower your risk of giving birth prematurely. [healthline.com]
These drugs, though not without some risk, help prevent breathing problems and vein hemorrhages, especially in very small infants with weak systems. [cbsnews.com]