Presentation
The book provides presentations of participants relating to selected aspects of immune regulation and its role in autoimmune thyroid diseases. [books.google.com]
Some eye muscle disorders are due to genetic problems that are present at birth. Other times, an eye injury or another medical condition can result in the development of eye muscle disorders later in life. [nicklauschildrens.org]
Broken pursuit is a non-specific sign if present in both directions and may occur with fatigue and anticonvulsant drugs. [jnnp.bmj.com]
The tremor cannot be due to a non-medication condition that was present prior to starting the medication and cannot continue to be present following discontinuation of the medication. [minddisorders.com]
Thurtell, MBBS, MSc February 9, 2015 Chief complaint " Double vision" History of Present Illness A 77-year-old female presented with a complaint of intermittent, binocular, horizontal diplopia that had been present for the last six months. [webeye.ophth.uiowa.edu]
Entire Body System
- Falling
In this condition, the border of the upper eyelid falls to a lower position than normal. In severe cases, the drooping eyelid can cover all or part of the pupil and interfere with vision. Ptosis can affect one or both eyes. [health.harvard.edu]
Some of the symptoms a person with a balance disorder may experience are: A sensation of dizziness or vertigo (spinning) Falling or a feeling of falling Lightheadedness or feeling woozy Visual blurring Disorientation Some individuals may also experience [masseyeandear.org]
People with RBD typically remember little nothing of this activity, unless they fall out of bed, bump into the furniture, or injure themselves and wake up. But they can usually remember and tell the dreams they were having during an episode. [healthcommunities.com]
When questioned, people will say, “I seem to catch my foot when I walk” or “I seem to fall over my own feet.” Trouble with stairs and with uneven surfaces is common. Not everyone with FSHD develops this lower leg problem. [mda.org]
Since the weak muscle is unable to bring the eye to a position in which the object is focused on the macula, the image falls on a more peripheral part of the retina. [dartmouth.edu]
- Weight Loss
The hypermetabolic state is characterized by fast pulse/heartbeat, palpitations, profuse sweating, high blood pressure, irritability, fatigue, weight loss, heat intolerance, and loss of hair and alterations in hair quality. [umkelloggeye.org]
This form of the disease is often associated with the systemic symptoms of temporal arteritis, which include severe headache, scalp tenderness, jaw pain, joint and muscle pain and weakness, fever, and unexplained weight loss, he said. [healio.com]
Exercise autonomous motivation predicts 3-year weight loss in women. Medicine & Science in Sports & Exercise. 2011;43:728–737. [PubMed] [Google Scholar] Steer RA, Ball R, Ranieri WF, Beck AT. [ncbi.nlm.nih.gov]
Gastrointestinal
- Muscle Rigidity
Other characteristics of neuroleptic-induced Parkinsonism are tremor and rigidity in muscles. [minddisorders.com]
Cardiovascular
- Hypertension
Retinopathy related to Pregnancy Induced Hypertension (preeclampsia, PIH) - Hypertensive retinopathy from PIH can cause numerous retinal hemorrhages and in some cases floaters or blind spots in the vision. [richmondeye.com]
People with nystagmus may hold their head in unusual positions or nod their head in an attempt to compensate for the condition. more information >> [back to top] Ocular Hypertension Ocular hypertension is an above-normal increase in the pressure in your [aoa.org]
Myasthenia Gravis Paralysis due to diabetes or hypertension Diabetes or high blood pressure may cause a relative ischemia (deprivation of blood supply). [strabismus.org]
Patients with nonarteritic ischemic optic neuropathy are typically 60 years old or more and may have vasculopathic risk factors including hypertension, diabetes, hyperlipidemia and smoking, Dr. Arnold said. [healio.com]
Past Ocular History Pseudophakia, both eyes (OU) No history of childhood strabismus Past Medical History Osteoporosis No history of diabetes, hypertension, or thyroid disease Medications Calcium Vitamin C Allergies None Family History Diabetes and cardiovascular [webeye.ophth.uiowa.edu]
Musculoskeletal
- Fracture
Orbital Fracture -- Blow-Out Fracture Traumatic contusion to the orbit (the bone surrounding the eyeball) may result in a fracture of the floor of the orbit known as a blow-out fracture. Diagnosis is best made with a CAT scan not a MRI. [strabismus.org]
Examples include entrapment of an eye muscle in a fracture of the eye socket and deposition of abnormal tissue in the eye socket as can occur with the form of hyperthyroidism called Graves disease. [msdmanuals.com]
INJURIES OF THE FACIAL NERVE A common cause of facial nerve injury is a skull fracture. This type of injury may occur immediately or may develop some days later due to nerve swelling. [michiganear.com]
Skin
- Skin Rash
Causes “pneumonia,” (skin) rashes, and seizures. Usually results from “exon” skipping in the gene encoding an enzyme necessary for the survIval of certain neurons that control sensation and involuntary responses. [richardsonthebrain.com]
Eyes
- Blurred Vision
Most Common Adult Vision Problems Blurred vision (called refractive errors) Age-related macular degeneration Glaucoma Cataract Diabetic retinopathy Most Common Childhood Vision Problems Blurred vision (called refractive errors) Crossed eyes (called strabismus [health.ny.gov]
Atropine eye drops: These may be used to blur vision in the unaffected eye. Atropine dilates the pupil, resulting in blurring when looking at things close up. This makes the lazy eye work more. [medicalnewstoday.com]
If you experience blurred vision, double vision, “floaters” in your vision, a sudden escalating headache, or dizziness, contact your doctor. Ophthalmoplegia is most often a symptom of another syndrome or disease. [healthline.com]
Learn how the medication known as Botox may reduce eyelid spasms, help crossed eyes, and treat other eye problems such as blurred vision (diplopia). [everydayhealth.com]
Convergence Insufficiency (CI) is the leading cause of eyestrain, blurred vision, double vision (diplopia), and/or headaches. 1 HIGHLIGHTS: Convergence insufficiency is a common near vision problem that -- due to recent scientific research -- is gaining [convergenceinsufficiency.org]
- Diplopia
Is the diplopia monocular or binocular? Whether the diplopia is monocular or binocular should be determined first. [jnnp.bmj.com]
Neuro-Ophthalmology Diplopia – Double Vision Diplopia, also known as double vision, occurs in one of two ways. The double vision is either present with one eye open (monocular diplopia) or only with both eyes open (binocular diplopia). [eye.uci.edu]
What is the significance of horizontal diplopia (where the images are side-by-side) as opposed to vertical diplopia? Answer 4-5. [dartmouth.edu]
Strabismus can cause vision loss, trouble with depth perception, or double vision (which doctors call diplopia). [everydayhealth.com]
- Eye Pain
Other symptoms, such as eye pain, bulging eye, or muscle weakness, can be present depending on the cause of double vision. [msdmanuals.com]
See an eye doctor immediately if you have any loss of eyesight, blurred vision, eye pain, double vision, redness, swelling of your eye or eyelid, or fluids coming from the eye. [my.clevelandclinic.org]
a stiff neck and severe eye pain. [eye.uci.edu]
Those with strabismus may experience: Double vision Difficulty focusing or judging distances Frequent blinking or squinting, especially in bright sunlight Tilting the head to look at things Frequent headaches Eye pain Nausea Prevention Strabismus cannot [visionweb.com]
Depending on the cause, you may also notice: Misalignment of one or both eyes (a "wandering eye" or "cross-eyed" appearance) Pain when you move your eye Pain around your eyes, like the temples or eyebrows Headache Nausea Weakness in your eyes or anywhere [webmd.com]
- Visual Impairment
Also known as cerebral visual impairment, cortical visual impairment (CVI) may be temporary or permanent. People with cortical visual impairment have difficulty using what their eye sees. [afb.org]
Cortical Visual Impairment : Cortical visual impairment (CVI) is vision loss due to any abnormality of the visual center in the brain. [dmei.org]
It is estimated that 4% of children suffer from this form of visual impairment. If not treated early enough, an amblyopic eye may never develop good vision and may even become functionally blind. Amblyopia has many causes. [wolfeeyeclinic.com]
Sources of support If eye dystonia is causing visual impairment, the following may be helpful sources of support: The Royal National Institute for Blind People (RNIB) Your local Sensory Support service. [dystonia.org.uk]
Speech disorder Speech impairment Speech impediment [ more ] 0002167 Optic atrophy 0000648 Strabismus Cross-eyed Squint Squint eyes [ more ] 0000486 Visual impairment Impaired vision Loss of eyesight Poor vision [ more ] 0000505 30%-79% of people have [rarediseases.info.nih.gov]
- Miosis
Miosis is constriction of the pupil. Mydriasis is dilation of the pupil. Myopia is an inability to see at distance ("nearsighted") with light focusing in front of the retina. [dartmouth.edu]
Horner's syndrome is a constellation of symptoms that includes miosis, pseudoptosis and enopthalmosis (sunken eyeball). It is characteristic of damage to the sympathetic innervation of the face provided by the superior cervical ganglion. [nba.uth.tmc.edu]
Neurologic
- Nystagmus
I know of no exercises or natural remedies for nystagmus. Andrew Weil, M.D. [drweil.com]
An oculographic reduction of the nystagmus is measured by the Nystagmus Acuity Function (NAF), considered a primary outcome. Phase II of the study includes binocular visual acuity as a second primary outcome. [clinicaltrials.gov]
Also known as: eye movement disorders, strabismus, nystagmus What are eye muscle disorders? The motion of the eyes as a person moves them to look around is controlled by muscles. [nicklauschildrens.org]
Nystagmus Nystagmus can be classified into two categories based on the velocity of both phases. [jnnp.bmj.com]
There is no cure for some kinds of eye movement disorders, such as most kinds of nystagmus. [icdlist.com]
- Confusion
Reversing or getting confused Children with visual processing problems commonly confuse their left with their right, or reverse letters, numbers, or words. This is why parents often suspect dyslexia. [visuallearningcenter.com]
At first, this may create double vision and confusion, but over time the brain will learn to ignore the image from the turned eye. [marioneye.com]
If we cannot do this easily, objects can appear double or move, creating a confusing uncomfortable view of the world. [drgallaway.com]
Weakness Muscles that weaken when they are used repeatedly Strength testing after a drug that relieves symptoms of myasthenia gravis is injected (edrophonium test) Wernicke syndrome History of long-term alcohol abuse Clumsiness, poor coordination, and confusion [msdmanuals.com]
Eye muscle surgery often creates confusion in the brain and makes eye teaming even more difficult unless vision therapy is done. [vision-therapy-pa.com]
- Seizure
The goal of surgery is to remove damaged or scarred tissue that serves as the focal point of a seizure. (Kolb, 112) Grand Mal Seizure : a generalized seizure disorder characterized by recurrent major motor seizures. [richardsonthebrain.com]
Can involve seizures, developmental delays, tooth or mouth problems. [apraxia-kids.org]
There are many causes, but the most common is the use of certain medications, including the anti-seizure drug Dilantin and sedatives that affect the function of the labyrinth, the part of the inner ear that senses movements of the head. [drweil.com]
[…] experts also urge you to call your doctor if you have any of the following symptoms during the first few weeks after an injection: shortness of breath or trouble swallowing; vision problems; trouble holding up your head or moving your face; fainting; seizures [everydayhealth.com]
Seizure 0001250 5%-29% of people have these symptoms Aplasia/Hypoplasia of the cerebellum Absent/small cerebellum Absent/underdeveloped cerebellum [ more ] 0007360 Hemiplegia/hemiparesis Paralysis or weakness of one side of body 0004374 Holoprosencephaly [rarediseases.info.nih.gov]
- Myoclonus
Myoclonus Myoclonus refers to involuntary movements that are sudden and brief. They can be classified as positive or negative. [med.umich.edu]
Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., opsoclonus-myoclonus syndrome). [icd9data.com]
[…] lower jaw [ more ] 0000347 Microphthalmia Abnormally small eyeball 0000568 Midface retrusion Decreased size of midface Midface deficiency Underdevelopment of midface [ more ] 0011800 Muscle weakness Muscular weakness 0001324 Muscular dystrophy 0003560 Myoclonus [rarediseases.info.nih.gov]
When it is present in association with palatal myoclonus, oculopalatal myoclonus, the lesion usually involves the red nucleus, dentate nucleus, and inferior olivary nucleus (Mollaret’s triangle). [jnnp.bmj.com]
- Papilledema
Visual disturbances are often associated with neurological disorders such as double vision, nystagmus, reduced visual field and acuity, a full or total loss of vision due to papilledema or a swollen optic disc. [eye.uci.edu]
Workup
Although a hypercoagulable workup may detect an abnormality, routine hematological workup may be unremarkable. Retinal vein occlusions are less common than arterial occlusions. [richmondeye.com]
Treatment
Treatment of Convergence Insufficiency Treatments for CI can be categorized as active or passive: Active treatment : A multi-site randomized clinical trial funded by the National Eye Insitute has proven that the best treatment for convergence insufficiency [convergenceinsufficiency.org]
There are no effective treatments for tardive dyskinesia once it develops. Tardive dyskinesia is associated and strongly correlated with the cumulative dose of the antipsychotic during years of treatment. [minddisorders.com]
"And this is true up to 29 years following radiation treatment." [news.stanford.edu]
Treatment during the active phase of the disease focuses on preserving sight and the integrity of the cornea as well as providing treatment for double vision when it interferes with daily functioning and becomes bothersome. [umkelloggeye.org]
Treatment can be effective and the sooner it begins, the better. Treatment Amblyopia is a relatively common problem. Treatment tends to be more effective the younger the child is. [medicalnewstoday.com]
Prognosis
Person’s living with ophthalmoplegia have a positive prognosis and can live a normal life, but this is largely based on the underlying cause. If ophthalmoplegia is diagnosed early on prognosis improves and there is a reduced risk of complications. [belmarrahealth.com]
The underlying cause of your ophthalmoplegia will affect your overall prognosis. Genetic and mitochondrial diseases, a history of vascular disease or stroke, or genetic syndromes can vary your outlook drastically. [healthline.com]
Prognosis The prognoses for the early- and intermediate-onset of movement disorders are very good, especially with the option of switching the patient to a newer antipsychotic such as clozapine. [minddisorders.com]
Outlook (Prognosis) Eye muscle surgery does not fix the poor vision of a lazy (amblyopic) eye. Your child may have to wear glasses or a patch. In general, the younger a child is when the operation is performed, the better the result. [ufhealth.org]
It is not intended to provide instruction and you should not rely on this information to determine diagnosis, prognosis or a course of treatment. It should not be used in place of a professional consultation with a doctor. [dystonia.org.uk]
Etiology
Involution of the intermuscular connective tissue septum between the lateral rectus and superior rectus is the etiology of the diplopia and strabismus in SES. [webeye.ophth.uiowa.edu]
Toxic effects from medications such as ethambutol are often suspected in the etiology of this disease, he said. A complete clinical evaluation is called for. [healio.com]
In my search of the literature, etiology is typically mentioned only when describing those cases excluded from a retrospective study. [vision-therapy-pa.com]
[Contribution on the etiology of the Stilling-Turk-Duane syndrome]. Acta Ophthalmol (Copenh). 1969. 47(2):415-23. [Medline]. Laughlin R. Hereditary paralysis of the abducens nerve. Am J Ophthalmol. 1937. 20:396. MacDonald AL, Crawford JS, Smith DR. [emedicine.medscape.com]
Epidemiology
Forensic Medicine (268) Medical Chemistry and Biochemistry (255) Neurology (248) Psychiatry, Psychology, Sexology (166) Genetics (165) Surgery, Traumatology and Orthopaedics (125) Infectology (98) Cardiology, Angiology (96) Endocrinology, Metabolism (91) Epidemiology [portal.mefanet.cz]
"[Epidemiological and clinical aspects of Stilling-Turk-Duane syndrome]". J. Fr. Ophtalmol. (in French). 19 (8–9): 533–42. PMID 8944136. Further reading [ edit ] Andrews, Caroline V.; Hunter, David G.; Engle, Elizabeth C. (1993). "Duane Syndrome". [en.wikipedia.org]
Epidemiology Frequency United States The frequency of Duane syndrome in the general population of individuals with eye movement disorders (strabismus) is approximately 1%-5%. [emedicine.medscape.com]
The epidemiology of depression. In: Gotlib IH, Hammen CL, editors. Handbook of depression. 2. New York: Guilford Press; 2009. pp. 5–22. [Google Scholar] Knapen J, Sommerijns E, Vancampfort D, Sienaert P, Pieters G, Haake P, Peuskens J. [ncbi.nlm.nih.gov]
Pathophysiology
Paediatrics, Neonatology (352) Internal Medicine (339) Physiology and Pathophysiology (338) Pathology and Forensic Medicine (268) Medical Chemistry and Biochemistry (255) Neurology (248) Psychiatry, Psychology, Sexology (166) Genetics (165) Surgery, Traumatology [portal.mefanet.cz]
IMAGING MRI of the orbits has been used to elucidate the pathophysiology of SES. Chaudhuri and Demer showed significant displacement of the LR-SR pulley in comparison to age-matched controls. [webeye.ophth.uiowa.edu]
Pathophysiology Neuropathologic, neuroradiologic, and neurophysiologic data Findings from neuropathologic, neuroradiologic, and neurophysiologic studies support the hypothesis that Duane syndrome results from an absence of cranial nerve VI (abducens nerve [emedicine.medscape.com]
Prevention
Can You Prevent Double Vision? Prevention of double vision relies on prevention of the underlying causes of the vision issue. [essilorusa.com]
[…] thyroid disease are reviewed; important observations with promising clinical implications in terms of immunogenetics of Graves' and Hashimoto's diseases are presented; and selection of appropriate therapy for Graves' thyrotoxicosis, and the possibility of preventive [books.google.com]
Treatments In an attempt to prevent acute dystonia from developing, physicians may prescribe a preventative medication along with the antipsychotic (see "Prevention," below). [minddisorders.com]
Preventing eye problems While eye problems and eye diseases become more prevalent with age, many can be prevented or corrected if you: See your family physician regularly to check for diseases that could cause eye problems, like diabetes. [my.clevelandclinic.org]