Presentation
It is the second most common malignant tumour of the lacrimal gland and presents as a painless mass with or without new increase in size. [eyeplastics.com]
Age and Sex edits from the Medicare Code Editor alert you to codes that are used only with patients of a specific age or sex, helping to ensure accurate reporting Present on Admission symbol highlights the diseases that will always be coded as present [books.google.com]
Clinics It most commonly presents as a gray-white lesion of the anterior chamber angle, but can present as a diffuse mass causing leukocoria (Broughton and Zimmerman, 1978). [atlasgeneticsoncology.org]
radiotherapy • Prognosis is poor as presentation is usually late 6. [slideshare.net]
Entire Body System
- Pain
Pain in or around the eye. This occurs mainly due to the pressure exerted by the tumor on the eye. Pain is rare in most eye cancers. It occurs when the cancer affects adnexal structures, nerves or spreads to other parts. Bulging of the eye. [news-medical.net]
Orbital pain, particularly in rapidly growing tumours. Increased retropulsion, which means increased resistance to digital pressure applied on the side of the tumour. [eyeplastics.com]
Although not cancerous, uterine fibroids can lead to heavy vaginal bleeding, bladder problems, or pelvic pain or pressure. Continued Another type of fibrous tissue tumor is a desmoid tumor. [webmd.com]
Key Symptoms Pain in the eyes Eye redness Change of color of the pupil or iris Obstructed vision Vision loss Pain in the eyes Secretion of mucus Headache Who to See and Treatments Available Usually, a person with pain, bulging, or redness in the eyes [docdoc.com]
- Hodgkin Lymphoma
Lymphomas in general may be Hodgkin’s or Non-Hodgkin’s in type. While Hodgkin’s lymphoma affects the blood, Non-Hodgkin’s lymphoma may affect other sites such as the brain, lungs or eyes. [news-medical.net]
Lymphomas that start in the eye are discussed in Non-Hodgkin Lymphoma. [cancer.org]
Lymphomas can also start in organs such as the lungs, stomach, and rarely, the eyes. The two main types of lymphoma are Hodgkin’s disease and non-Hodgkin’s lymphoma. Primary intraocular lymphoma is always a non-Hodgkin’s B cell lymphoma. [aao.org]
Many doctors consider intraocular lymphoma to be a type of central nervous system lymphoma. Most intraocular lymphomas are non-Hodgkin lymphoma. Retinoblastoma is a rare form of childhood eye cancer. [cancer.net]
Lymphoma/Leukemia Lymphoma tumors can appear in the eyelid tissue, tear ducts and the eye itself. In most patients with large cell non-Hodgkin's lymphoma, the disease is confined to the eye and central nervous system. [eyecancermd.org]
- Pathologist
Evaluation of the biopsy specimen should be performed by an experienced ophthalmic pathologist. If there isn’t an ophthalmic pathologist in your area, you can request that the histopathology slides be sent for second opinion. [eyecancer.com]
The lesion is then sent to an expert eye pathologist for a definitive reading. [premiermedicalbaldwin.com]
A formal review of the pathologic material was performed by at least one pathologist in each institution. Confirmation of cervical invasion and staging was made by the review of these pathologic reports. [nature.com]
- Weakness
Symptoms may include headache and weakness on one side, seizures, personality changes, and visual problems. Sometimes the doctor will choose to watch the tumor for a time. [webmd.com]
Chemotherapy can leave kids feeling nauseated, weak, dizzy, or feverish. Radiation therapy might make kids feel more tired. Their skin can get red or dry in the area being treated. [kidshealth.org]
She denied any difficulty swallowing, weakness, shortness of breath, or trauma. Past Ocular History: Wears spectacles. No ocular surgery or trauma. Medical History: Negative Medications: None Family History: Father died of esophageal cancer. [webeye.ophth.uiowa.edu]
To date, these studies have found only weak associations or yielded contradictory results.[ 3 ] Similarly, there is no consistent evidence that occupational exposure to UV light or other agents is a risk factor for uveal melanoma.[ 3, 5 ] Anatomic Location [cancer.gov]
- Malaise
Management and Prognosis When a suspicious ocular mass is found, it is important to ask the patient whether they have had any ocular surgery or trauma; a history of cancer; or any systemic symptoms of cancer, such as anorexia, weight loss, general fatigue, malaise [reviewofoptometry.com]
Gastrointestinal
- Diarrhea
AEs depend on the type and dosage of drugs, how they are administered, and the length of therapy. 2 Common AEs of systemic ChT include hair loss, mouth sores, loss of appetite, nausea and vomiting, diarrhea or constipation, increased risk of infections [uspharmacist.com]
Skin
- Keratosis
Some types of benign lesions include squamous papilloma, keratoacanthoma, hereditary benign intraepithelial dyskeratosis, keratotic plaque, actinic keratosis, pterygium and pingueculum. [eyeworld.org]
Alternative uses IFNα-2b has been used to treat other types of tumors including cervical intraepithelial neoplasia, actinic keratosis and metastatic malignant melanoma [59, 60]. [eandv.biomedcentral.com]
- Hyperkeratosis
Pathologically, they are brought on by hyperkeratosis and acanthosis with neutrophilic infiltrate and microabscesses. They should be treated with excision. [eyeworld.org]
Eyes
- Photopsia
This had been happening for about three weeks; he denied photopsia. The patient’s systemic history was significant for hypertension, heart problems (having had two valve replacements) and type 2 diabetes that was controlled with oral medications. [reviewofoptometry.com]
When symptoms develop they can include blurred vision, double vision (diplopia), irritation, pain, a perception of flashes of light in the eye (photopsia), a reduction in the total field of vision, and loss of vision. [rarediseases.org]
Workup
The workup of suspected metastatic scirrhous breast cancer to the orbit includes a complete history and physical, imaging of the orbit (CT or MRI), mammogram, orbital mass biopsy and body imaging for metastatic disease. [webeye.ophth.uiowa.edu]
Clinical Testing and Workup An eye doctor may suspect ocular melanoma following a routine eye exam. Individuals may visit an eye doctor because of problems with vision or soreness in one eye. [rarediseases.org]
Treatment
We did not analyse the associations between patient and prescriber characteristics, and treatment selection and subsequent clinical outcomes of treatments. [bmjopen.bmj.com]
Many choroidal hemangiomas can be safely monitored by your eye doctor without the need of further treatment. Photographs can be used to document evidence of growth or leakage and the need for treatment. [eyecancermd.org]
Surgical treatment for en masse removal is advocated. [eyeplastics.com]
Causes and treatment vary by age group. Benign pediatric tumors are most commonly dermoid tumors and vascular lesions such as capillary hemangioma and lymphangioma. Treatment of dermoid tumors is excision. [merckmanuals.com]
Treatment of retinoblastoma. New York: Churchill Livingston, 1985: 3–93 Google Scholar 72. Shields CL, Shields JA, Cater J, et al. Plaque radiotherapy for retinoblastoma: long-term tumor control and treatment complications in 208 tumors. [doi.org]
Prognosis
Prognosis The prognosis for all forms of nevi tends to be good with iris nevi showing enlargement in less than 5% of cases (Territo et al., 1988). [atlasgeneticsoncology.org]
Stages and Outlook (Prognosis) After a cancer diagnosis, staging provides important information about the extent of cancer in the body and anticipated response to treatment. [cancer.org]
• Ultrasound may be necessary • Treatment – enucleation, local resection, radiotherapy • Prognosis is poor as presentation is usually late 6. [slideshare.net]
Prognosis The outlook depends on the size of the tumor when it's diagnosed. The prognosis is better if the cancer is contained within the eye and has not spread to other parts of the body. [drugs.com]
Melanoma Malignant tumor often detected when small size so prognosis is usually favorable. Nevus Benign tumor that classically remains stable. Can lead to reduced visual acuity. Can transform into melanoma. [isoo.org]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
[…] anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology [ncbi.nlm.nih.gov]
Disease Medulloepithelioma Etiology Medulloepithelioma is a tumor that arises from the epithelium of the medullary tube, most often the ciliary body. [atlasgeneticsoncology.org]
Inflammatory etiologies, while not uncommon, include dacryoadenitis, sarcoidosis, and orbital inflammatory pseudotumor. For the purposes of this discussion, the focus will be on neoplastic lesions of the lacrimal gland. [emedicine.com]
During follow-up, we evaluated mortality, readmission (caused by tumor, heart, or other etiology), incidence of tumor recurrence or appearance of new neoplasia during follow-up. [revespcardiol.org]
Epidemiology
[…] options Subheadings: analysis anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology [ncbi.nlm.nih.gov]
Epidemiology Choroidal melanomas are found most often in countries with large populations of people of northern European decent. [atlasgeneticsoncology.org]
Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/statistics/summaries.html. Accessed February 28, 2015. 18. Edge SB, Compton CC. [uspharmacist.com]
Ocular melanoma – when you have seen one, you have not seen them all: a clinical outcome study from the Surveillance, Epidemiology, and End Results (SEER) database (1973-2012). [rarediseases.org]
Content type: Research article Epidemiological and histopathological profile of malignant melanoma in Malawi Studies on malignant melanoma have largely focused on Caucasian populations due to higher incidence in lighter-skinned individuals. [bmcclinpathol.biomedcentral.com]
Pathophysiology
The pathophysiology of this uncommon... [bmcclinpathol.biomedcentral.com]
Pathophysiology of ocular surface squamous neoplasia. Exp Eye Res. 2014;129:172–82. Article CAS PubMed PubMed Central Google Scholar McClellan AJ, McClellan AL, Pezon CF, Karp CL, Feuer W, Galor A. [eandv.biomedcentral.com]
Prevention
How can they be prevented? Intraocular tumours cannot be prevented, but they can be diagnosed in their early stages. [imo.es]
The goal of treatment in ocular melanoma is to prevent it from spreading (metastasis). [healthline.com]
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Finger disagrees with this theory and its so called “no touch technique” that requires surgeons to get new instruments after each time they touch the tumor (to prevent transplantation). [eyecancer.com]
Sunglasses to prevent choroidal melanoma? There is a higher incidence of choroidal melanoma in people with blue eyes and people that work outdoors. [mastereyeassociates.com]