Presentation
Case presentation A 3-year-old boy presented for evaluation of multiple facial nodules that had been present for six months. After their initial appearance, the lesions sporadically fluctuated in size but never resolved completely. [escholarship.org]
Lesions may be present for weeks or months and tend to follow a chronic course. [accessmedicine.mhmedical.com]
[…] with a history of a red-brown well-circumscribed lesion present on the face for a long duration. [dermatologyadvisor.com]
Entire Body System
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Cat Scratch
Cultures for mycobacteria and cat scratch disease serologies were negative. Antibiotic therapy was ineffective; the lesion healed spontaneously with a mean duration of 11 months. [ncbi.nlm.nih.gov]
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Plethora
J Cutan Aesthet Surg 2011;4:156-7 Sir, Despite evaluation of a plethora of modalities, treatment of Granuloma Faciale (GF) remains disappointing. [jcasonline.com]
Gastrointestinal
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Loss of Appetite
Common side-effects mentioned in the summary of product characteristics (SPC) include nausea and loss of appetite. [medicaljournals.se]
Skin
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Facial Skin Lesion
skin lesions whose course is chronic and slowly progressive. 3 Diagnosis is based on clinical features, histopathology and, more recently, dermatoscopy. 1 Multiple modalities of medical and surgical treatment have been suggested, but none has proved [ncbi.nlm.nih.gov]
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Skin Ulcer
There was no skin ulceration. No photosensitivity, fever or joint pain was present. Past and personal history was unremarkable. Figure 1: Before treatment - single, grey-brown nodule with prominent follicular orifices over left cheek. [jcasonline.com]
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Night Sweats
The patient was otherwise systemically well, with no fevers, night sweats, fatigue, weight loss, or symptoms of infection. [karger.com]
Face, Head & Neck
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Facial Edema
Among these, there were 68% (27/40) cases of orofacial granulomatosis and 43% (3/7) cases of solid facial edema. [53] In an unpublished study conducted in our department, 10 (52.6%) of 19 cases of clinically diagnosed granulomatous cheilitis showed granulomas [ijdpdd.com]
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Facial Burn
A mucosal variant of the skin lesion granuloma faciale. Burns BV, Roberts PF, De Carpentier J, Zarod AP. Department of Otolaryngology, North Manchester General Hospital, Manchester. [thedoctorsdoctor.com]
Workup
Such a reaction should prompt referral to an allergist or rheumatologist for allergy and autoimmune workup. Major complications. More significant complications include migration of the filler, granuloma formation, and infection. 3 Migration. [aao.org]
Microbiology
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Afipia Felis
We recorded clinical details about the nodule and its duration, ultrasound study pattern, cultures for bacteria and mycobacteria, and Bartonella henselae and Afipia felis antibody testing. [ncbi.nlm.nih.gov]
Ultrasound studies have shown that the lesions are solid and cultures for bacteria and mycobacteria, and antibody tests for Bartonella henselae and Afipia felis are negative [ 4 ]. [escholarship.org]
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Bartonella Henselae
Bartonella henselae titers and the Coccidioidomycosis immitis immunodiffusion test were negative; a Tuberculin Skin Test was non-reactive. [escholarship.org]
We recorded clinical details about the nodule and its duration, ultrasound study pattern, cultures for bacteria and mycobacteria, and Bartonella henselae and Afipia felis antibody testing. [ncbi.nlm.nih.gov]
Other Pathologies
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Granulomatous Tissue
tissue L92.9 (abnormal) (excessive) ICD-10-CM Codes Adjacent To L92.9 L91 Hypertrophic disorders of skin L91.0 Hypertrophic scar L91.8 Other hypertrophic disorders of the skin L91.9 Hypertrophic disorder of the skin, unspecified L92 Granulomatous disorders [icd10data.com]
Treatment
Treatment Options Treatment options are summarized in Table I. Table I. Treatment options for granuloma faciale. [dermatologyadvisor.com]
Treatment Options Treatment options are summarized in Table I. Table I. [psychiatryadvisor.com]
The treatments were performed with 5 mm minimally overlapping spots at 8.0 J/cm 2 for the first treatment and 8.5 J/cm 2 for the second treatment. No anesthesia was needed and there was no significant postoperative discomfort. [jamanetwork.com]
This case supports previous reports of successful treatment of GF with topical tacrolimus. Keywords: Granuloma faciale, tacrolimus, treatment How to cite this article: Gupta L, Naik H, Kumar NM, Kar HK. [jcasonline.com]
Prognosis
The patients were reviewed according to demographics, location, treatment, and prognosis. Follow-up was obtained through a questionnaire sent to each referring physician. [mdedge.com]
Etiology
Granuloma faciale (GF) is an uncommon cutaneous disease of uncertain etiology that predominantly affects the face. Extrafacial lesions are rare. [mayoclinic.pure.elsevier.com]
Etiology and Pathophysiology Etiology and pathogenesis are not clearly defined, but several hypotheses exist. Some cases are idiopathic. [unboundmedicine.com]
[…] and Pathogenesis The etiology of granuloma faciale is unknown. [plasticsurgerykey.com]
Etiology is unknown. Early cases of granuloma faciale were reported as “eosinophilic granuloma” of the skin. [accessmedicine.mhmedical.com]
Epidemiology
Epidemiology Primarily a disease of middle-aged white men with rare reports of GF in Japanese, blacks, and children Incidence/Prevalence Rare; precise incidence and prevalence are unknown. [unboundmedicine.com]
OBJECTIVES: To improve our epidemiological, clinical and pathological knowledge on IFAG, to search for an infectious aetiology, and to assess therapeutic recommendations. [ncbi.nlm.nih.gov]
Epidemiology Early cases of granuloma faciale were reported as “eosinophilic granuloma” of the skin. [plasticsurgerykey.com]
Pathophysiology
Case Overview granuloma faciale Member Rated 0 Patient case no. 1546 Date added 16 April 2003 Patient details Age --Undetermined-- Localisation Head / face / cheek Primary Lesions Plaque / erythematous Pathophysiology reactive conditions / eosinophilic [dermquest.com]
Etiology and Pathophysiology Etiology and pathogenesis are not clearly defined, but several hypotheses exist. Some cases are idiopathic. [unboundmedicine.com]
Regarding the pathophysiology, our study rules out a primary infectious disease, and allows considering IFAG either as a granulomatous process appearing around an embryological residue or as a manifestation to include in the spectrum of granulomatous [ncbi.nlm.nih.gov]
Pathophysiology The skin is the primary organ system that is affected. [emedicine.medscape.com]
Prevention
How can Granuloma Faciale be Prevented? Currently, there are no known methods to prevent Granuloma Faciale occurrence. However, some of the risk factors may be recognized and controlled. [dovemed.com]
The characteristic appearance and location of the lesions in the absence of adenopathy and constitutional symptoms should make the clinical diagnosis straightforward and prevent unnecessary interventions. [escholarship.org]
We take the utmost care to prevent poor voice outcomes. [voicedoctorla.com]
Counselling the patient and adopting preventative measures such appropriate filler choice and prevention of infection should be part of every case of dermal filler injections. [aestheticsjournal.com]