Case presentation A 3-year-old boy presented for evaluation of multiple facial nodules that had been present for six months. After their initial appearance, the lesions sporadically fluctuated in size but never resolved completely. [escholarship.org]

[…] with a history of a red-brown well-circumscribed lesion present on the face for a long duration. [dermatologyadvisor.com]

Lesions may be present for weeks or months and tend to follow a chronic course. [accessmedicine.mhmedical.com]

Telangiectases and scaling may be present. Spontaneous healing with atrophic scarring is the sequel. Lesion may persist for years. [ijdvl.com]

• Inflammation

  Ultrasonography of IFAG nodules shows a well-demarcated hypoechoic lesion located in dermis only. 3 But chalazions—which are due to meibomian gland inflammation—are located inside eyelid tarsus. 4 IFAG nodules are thought to be related to a granulomatous [nature.com]

  including perivascular inflammation with nuclear dust, and damage in the vessel wall, are frequently observed, although it was not present in this case. [ncbi.nlm.nih.gov]

  The diagnosis rendered at that time was fibrosis and chronic inflammation. The subsequent clinical course was one of recurrence and intractable progressive growth over a 1- to 2-year period. [the-dermatologist.com]

• Nasal Congestion

  No other findings of pathological significance in the rest of the study Given these images of sinus compromise, nasal congestion and subsequent discharge reported by the patient, it was decided to complete the study with computed tomography (CT) of the [head-face-med.biomedcentral.com]

• Hepatosplenomegaly

  There was no palpable lymphadenopathy or hepatosplenomegaly, and the general examination was otherwise unremarkable. [karger.com]

• Follicular Plugging

  Abstract GRANULOMA faciale is characterized by reddish-brown elevated plaques or nodules with follicular plugging which develop mainly on the face. 1 Although the lesions are asymptomatic and have never been associated with systemic disease, they are [mdedge.com]

  Follicular plugging was not prominent. The mass was firm, rubbery, and mobile on palpation (Fig. 1 ). There was a flattened, erythematous, atrophic plaque with induration in the left posterior axilla (Fig. 2 ). [karger.com]

  The overlying epidermis is acanthotic with follicular plugs that are often parakeratotic. [ijdpdd.com]

• Facial Skin Lesion

  It is characterized by skin lesions predominantly facial whose course is chronic and slowly progressive. The diagnosis is based on clinical features, histopathology and, more recently, in dermoscopy. [ncbi.nlm.nih.gov]

• Skin Ulcer

  There was no skin ulceration. No photosensitivity, fever or joint pain was present. Past and personal history was unremarkable. Figure 1: Before treatment - single, grey-brown nodule with prominent follicular orifices over left cheek. [jcasonline.com]

• Blister

  These cystic collections of keratin just under the epidermal surface can also occur with porphyria cutanea tarda and other blistering diseases. [clevelandclinicmeded.com]

• Skin Pustule

  Skin pustules show deep neutrophilic infiltrate. Erythema nodosum-like lesions show early lymphocytic infiltration within the fat and deep dermis; later many neutrophils are present. [atlases.muni.cz]

• Facial Edema

  It shows perivascular and perifollicular lymphocytic infiltrates with giant cells and dermal edema. [55] Facial aseptic granuloma presents as an asymptomatic erythematous nodule over the cheeks in children. [ijdpdd.com]

It shows readers how to use their basic science knowledge to identify the possible causes of each symptom, and describes the procedures and laboratory tests that need to be included in the workup. [books.google.es]

Such a reaction should prompt referral to an allergist or rheumatologist for allergy and autoimmune workup. Major complications. More significant complications include migration of the filler, granuloma formation, and infection. 3 Migration. [aao.org]

• Neutrophilia

  Diagnosis [ edit ] Skin biopsy for histopathology: Focal LCV, diffuse dermal neutrophilia with leukocytoclasia, tissue eosinophilia & perivascular fibrosis. [en.wikipedia.org]

• Granulomatous Tissue

  ICD-10-CM Codes › L00-L99 Diseases of the skin and subcutaneous tissue › L80-L99 Other disorders of the skin and subcutaneous tissue › L92- Granulomatous disorders of skin and subcutaneous tissue › Granulomatous disorder of the skin and subcutaneous tissue [icd10data.com]

Treatment Options Treatment options are summarized in Table I. Table I. [dermatologyadvisor.com]

The patient returned after nine months of treatment with partial improvement (Figure 4). FIGURE 4 Post treatment. [scielo.br]

The patient returned after nine months of treatment with partial improvement (Figure 4). Post treatment. [ncbi.nlm.nih.gov]

Treatment with topical psoralen and UVA. J Am Acad Dermatol 1983;8:559. 20. Wheeland RG, Ashley JR, Smith DA. Carbon dioxide laser treatment of granuloma faciale. J Dermatol Surg Oncol 1984;10:730-3. 21. Elston DM. [content.sciendo.com]

Clinical course and prognosis of the disease depend on the age of initial manifestation as well as the location and the organs involved [ 8 ]. [head-face-med.biomedcentral.com]

The patients were reviewed according to demographics, location, treatment, and prognosis. Follow-up was obtained through a questionnaire sent to each referring physician. [mdedge.com]

Granuloma faciale (GF) is an uncommon cutaneous disease of uncertain etiology that predominantly affects the face. Extrafacial lesions are rare. [mayoclinic.pure.elsevier.com]

Etiology is unknown. Early cases of granuloma faciale were reported as “eosinophilic granuloma” of the skin. [accessmedicine.mhmedical.com]

Etiology and Pathophysiology Etiology and pathogenesis are not clearly defined, but several hypotheses exist. Some cases are idiopathic. [unboundmedicine.com]

[…] and Pathogenesis The etiology of granuloma faciale is unknown. [plasticsurgerykey.com]

OBJECTIVES: To improve our epidemiological, clinical and pathological knowledge on IFAG, to search for an infectious aetiology, and to assess therapeutic recommendations. [f1000.com]

Epidemiology Primarily a disease of middle-aged white men with rare reports of GF in Japanese, blacks, and children Incidence/Prevalence Rare; precise incidence and prevalence are unknown. [unboundmedicine.com]

Epidemiology Early cases of granuloma faciale were reported as “eosinophilic granuloma” of the skin. [plasticsurgerykey.com]

Case Overview granuloma faciale Member Rated 0 Patient case no. 1546 Date added 16 April 2003 Patient details Age --Undetermined-- Localisation Head / face / cheek Primary Lesions Plaque / erythematous Pathophysiology reactive conditions / eosinophilic [dermquest.com]

Regarding the pathophysiology, our study rules out a primary infectious disease, and allows considering IFAG either as a granulomatous process appearing around an embryological residue or as a manifestation to include in the spectrum of granulomatous [f1000.com]

Etiology and Pathophysiology Etiology and pathogenesis are not clearly defined, but several hypotheses exist. Some cases are idiopathic. [unboundmedicine.com]

Understanding their pathophysiology is essential in differential diagnosis and appropriate management. [aestheticsjournal.com]

We take the utmost care to prevent poor voice outcomes. [voicedoctorla.com]

Counselling the patient and adopting preventative measures such appropriate filler choice and prevention of infection should be part of every case of dermal filler injections. [aestheticsjournal.com]

How can Granuloma Faciale be Prevented? Currently, there are no known methods to prevent Granuloma Faciale occurrence. However, some of the risk factors may be recognized and controlled. [dovemed.com]

There is no known preventive for granuloma inguinale, although it is rare where sanitary living conditions prevail. The drainage from lesions may be infectious and handwashing and basic cleanliness are required. [medical-dictionary.thefreedictionary.com]