In a retrospective chart review of 273 eyes in 145 patients, Ranchod et al described the clinical presentation of FEVR patients.[41] The mean age at presentation was 58.6 months. [eyewiki.aao.org]

We also report our outcomes in early treatment of this inherited disorder. Methods: Retrospective interventional and descriptive case series of 11 patients (17 eyes) affected by FEVR evaluated and treated in our hospital. [semanticscholar.org]

An examination under anesthesia may be required for diagnosis, imaging acquisition, and treatment. [eyewiki.aao.org]

It was found that patients who were diagnosed before the age of 3 had a more severe clinical course with very poor visual prognosis. The most rapid progression is generally seen in children and adolescents. [eyewiki.aao.org]

[…] at least 10 genes have been implicated in association with FEVR including FZD4,[6][7] NDP,[8][9] LRP5, [7][10][11] TSPAN12,[12][13][14] ZN408, [15] KIF11,[16][17] [18][19]CTNNB1,[20][21] JAG1,[22] RCBTB1,[23] ATOH7,[24] DOCK6,[25] and ARHGAP31.[25] Epidemiology [eyewiki.aao.org]

Familial Exudative Vitreoretinopathy: Pathophysiology, Diagnosis, and Management. Asia Pac J Ophthalmol (Phila). 2018 May-Jun;7(3):176-182 ↑ 50.0 50.1 50.2 Nikopoulos K, Venselaar H, Collin RWJ, et al. [eyewiki.aao.org]

The disorder prevents blood vessels from forming at the edges of the retina, which reduces the blood supply to this tissue. The signs and symptoms of familial exudative vitreoretinopathy vary widely, even within the same family. [medlineplus.gov]

Mukai Medicine International ophthalmology clinics 1993 Early detection of familial exudative vitreoretinopathy plays an important role on preventing the progression of the diseases and improving the vision of patient and his/her family. [semanticscholar.org]