In the present report, two of three patients were boys and all patients were male. The clinical features of ALP are variable. [ncbi.nlm.nih.gov]

At present, however, there is little evidence to suggest that the disease is genetically determined. We recently had the opportunity of observing three patients who had lichen planus, each with a positive family history. Report of Cases. [jamanetwork.com]

Nail LP presents in 10 to 25 percent of LP patients and tends to present as roughness, vertical ridges or cracks, and thinning of the nail. This can eventually lead to scarring of the nail. [rarediseases.org]

Hellier Medicine 1940 This paper presents an analysis of figures based on patients attending the Dermatological Department of the General Infirmary at Leeds, and particular attention is paid to the effect of climatic changes on the incidence of various [semanticscholar.org]

• Turkish

  Turkish. [Google Scholar] 7. Kanwar AJ, De D. Lichen planus in childhood: report of 100 cases. Clin Exp Dermatol. 2010;35:257–262. [PubMed] [Google Scholar] 8. Shahriar SA. Familial actinic lichen planus: case reports in two brothers. [ncbi.nlm.nih.gov]

• Suggestibility

  The recent demonstration of immunoglobulins in lichen planus lesions1 suggests an autoimmune pathogenesis for this disease. At present, however, there is little evidence to suggest that the disease is genetically determined. [jamanetwork.com]

  More frequent than previously suggested? J Am Acad Dermatol. 1985 Jul;13(1):50-4. [PubMed: 4031153] 14. Scully C, el-Kom M. Lichen planus: review and update on pathogenesis. J Oral Pathol. 1985 Jul;14(6):431-58. [PubMed: 3926971] 15. [ncbi.nlm.nih.gov]

[…] immunoglobulin A [IgA]) and complement Linear or shaggy deposits of fibrin and fibrinogen in the basement membrane zone In the upper dermis, a bandlike infiltrate of lymphocytic (primarily helper T) and histiocytic cells with many Langerhans cells See Workup [emedicine.medscape.com]

Treatments for Cutaneous Lichen Planus: A Systematic Review and Meta-Analysis. Am J Clin Dermatol. 2016 Feb. 17(1):11-22. [QxMD MEDLINE Link]. Fazel N. Cutaneous lichen planus: A systematic review of treatments. [emedicine.medscape.com]

Treatment-induced remission is typically followed by relapse. Thus, asymptomatic oral LP should not be treated as the side-effect burden of treatment is high. [ncbi.nlm.nih.gov]

While this patient was undergoing treatment, violaceous, flat-topped papular [jamanetwork.com]

Standard Therapies Treatment In mild cases, symptoms may be minimal or absent and no therapy may be needed. For patients requiring treatment, first line therapy is usually a topical corticosteroid medication. [rarediseases.org]

Treatment of lichen planus with a short course of oral prednisolone. Br Dermatol, 123 (1990), pp. 550-551 [Viglioglia et al., 1990] P.A. Viglioglia, C.R. Villanueva, A.D. Martorano, A.M. Cahuege, C.A. Traballi, J.M. Geiger. [elsevier.es]

The prognosis for lichen planus is good, as most cases regress within 18 months. [emedicine.medscape.com]

Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. The Scientific World Journal. Volume 2014, Article ID 742826. Manousaridis I, Manousaridis K, Peitsch WK & Schneider S W. [rarediseases.org]

The simultaneous presence of both diseases has been described in many reports, possibly related to the use of antimalarials in the treatment of LE.[27][31] Prognosis Cutaneous LP often clears spontaneously within 1 to 2 years, but residual hyperpigmentation [ncbi.nlm.nih.gov]

Onset or exacerbation of lichen planus has also been linked to stressful events. [14] Etiology The exact cause of lichen planus is not known, although it is immunologically mediated. [emedicine.medscape.com]

By contrast, oral LP is a chronic disease that may or may not remit.[2] Drug-induced LP gradually resolves after removal of the causative medication.[3] Etiology Lichen planus is an idiopathic disease. [ncbi.nlm.nih.gov]

Lichen planopilaris epidemiology: a retrospective study of 80 cases. An Bras Dermatol. 2015 Sep-Oct;90(5):666-70. [PMC free article: PMC4631232] [PubMed: 26560212] 24. Errichetti E, Figini M, Croatto M, Stinco G. [ncbi.nlm.nih.gov]

Epidemiology Frequency United States Lichen planus is reported in approximately 1% of all new patients seen at health care clinics. Some areas have reported a higher incidence in December and January. [emedicine.medscape.com]

Pathophysiology Lichen planus is a cell-mediated immune response of unknown origin. [emedicine.medscape.com]