Clinical manifestations (present in some, but not all) were usually relatively mild (predominantly chronic headache and plethora) and relieved by phlebotomy (see Management ). [ncbi.nlm.nih.gov]

],[14],[15],[16] Of note, this clinical variability has been observed within the members of the same affected family.[6] The vast majority of PFCP patients manifested clinically with mild hyperviscosity features such as fatigue, dizziness, headache, plethora [jahjournal.org]

He had headaches and marked plethora. Erythropoietin levels were not elevated. The disorder was characterized in middle age in other members of the family by hypertension, cardiovascular and thromboembolic phenomena, and abnormal bleeding. [datapunk.net]

Typical findings for polycythemia: In many children the only manifestation will be plethora. Alternatively, polycythemia may be discovered inadvertently on a routine CBC. Other symptoms may include headache, pruritus, dizziness and sweating. [clinicaladvisor.com]

McMullin MF, Bareford D, Campbell P, Green AR, Harrison C, Hunt B, et al. Guidelines for the diagnosis, investigation and management of polycythaemia/erythrocytosis. Br J Haematol 2005;130:174-95. [PUBMED] 46. Winslow RM. [jahjournal.org]

Cold Spring Harb Symp Quant Biol. 1992; 57 :95–106. [ PubMed : 1339709 ] McMullin MF, Bareford D, Campbell P, Green AR, Harrison C, Hunt B, Oscier D, Polkey MI, Reilly JT, Rosenthal E, Ryan K, Pearson TC, Wilkins B., General Haematology Task Force of [ncbi.nlm.nih.gov]

Block AJ, Boysen PG, Wynne JW, Hunt LA: Sleep apnea, hypopnea and oxygen desaturation in normal subjects. A strong male predominance. N Engl J Med 300:513, 1979. 40. [medtextfree.wordpress.com]

No digital infarcts, ulcers or gangrene was seen. Chest, cardiovascular system and central nervous system examinations including fundus examination were normal. [sjmms.net]

289.52 Splenic sequestration 289.53 Neutropenic splenomegaly 289.59 Other diseases of spleen 289.7 Methemoglobinemia 289.81 Primary hypercoagulable state 289.82 Secondary hypercoagulable state 289.83 Myelofibrosis 289.84 Heparin-induced thrombocytopenia [healthprovidersdata.com]

The hematological features include the presence of isolated erythrocytosis without evolution into leukemia or other myeloproliferative disorders, absence of splenomegaly, normal white blood cell and platelet counts, and low plasma EPO levels. [orpha.net]

The mean RBC volume at diagnosis and the incidence of splenomegaly appear to be higher in familial than nonfamilial cases. [mdedge.com]

Examination revealed a conscious, cooperative, well-built man with a plethoric look, ruddy complexion, mild icterus, mild conjunctival injection, macroglossia with a deep median fissure, tongue tie, an accessory thumb on the left hand, a pulse rate of [sjmms.net]

Physical examination is only significant for BMI of 32.46 otherwise no skin discoloration or cyanosis. [dc.etsu.edu]

Examination revealed a conscious, cooperative, well-built man with a plethoric look, ruddy complexion, mild icterus, mild conjunctival injection, macroglossia with a deep median fissure, tongue tie, an accessory thumb on the left hand, a pulse rate of [sjmms.net]

Typical symptoms include red skin cyanosis, expressed headaches, exertional dyspnea, tachycardia and disruption of the heart. [medicalformat.com]

Complication Familial erythrocytosis complications Complications of polycystic kidney kidney tuberculosis kidney cancer Erythrocytosis common symptoms are dizziness, headache, headache, fatigue, palpitations, insomnia, eyes afraid of hot sweating; sometimes [healthfrom.com]

Lethargy, confusion, headache, dizziness These symptoms are due to central nervous system disturbances with hyperviscosity causing poor perfusion[3]. [explainmedicine.com]

Here we discuss a case of Familial Polycythemia likely due to novel hemoglobin variant. 42-year Caucasian male presents to the clinic with high hemoglobin for several years but otherwise denies any symptoms of headache, vision changes, chest pain. [dc.etsu.edu]

This may cause sluggishness, irritability, headache, dizziness, fainting, disturbances of sensation in the hands and feet, and a feeling of fullness in the head. There may be episodes of acute pain as spontaneous clots occur in the blood vessels. [medical-dictionary.thefreedictionary.com]

Arcasoy MO, Degar BA, Harris KW, Forget BG. Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene. Blood 1997;89:4628-35. [PUBMED] 14. Sokol L, Luhovy M, Guan Y, Prchal JF, Semenza GL, Prchal JT, et al. [jahjournal.org]

Haematologica. 2008; 93 :1072–5. [ PubMed : 18492694 ] Arcasoy MO, Degar BA, Harris KW, Forget BG. Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene. [ncbi.nlm.nih.gov]

Arcasoy MO, Degar BA, Harris KW, Forget BG: Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene. Blood 89:4628, 1997. 58. [medtextfree.wordpress.com]

The hyperviscosity syndrome is characterized by symptoms including headache, dizziness, fatigue, lassitude, visual and auditory disturbances, paresthesia, and myalgia, and may be associated with altered mental status. [ncbi.nlm.nih.gov]

increased to the organization to reduce oxygen, Tissue hypoxia to stimulate erythropoietin increased, resulting in increased red blood cells. [healthfrom.com]

increase of 4% for each 1000-m increase in altitude), congenital methemoglobinemia, and other high–oxygen affinity hemoglobinopathies stimulating increased Epo production. [findmeacure.com]

NEUROLOGIC Central nervous system Headaches,Dizziness,Intracerebral hemorrhage LABORATORY ABNORMALITIES Low or normal serum erythropoietin INHERITANCE Autosomal dominant HEMATOLOGY Erythrocytosis,Increased red blood cell mass,Increased hematocrit,Increased [datapunk.net]

Increased hemoglobin; Normal oxygen affinity of hemoglobin; Hypersensitivity of erythroid colony-forming units to erythropoietin (EPO, 133170 ) LABORATORY ABNORMALITIES: Low or normal serum erythropoietin MISCELLANEOUS: Fatigue; Variable phenotype, [genome.jp]