Presentation
Presents a more streamlined format to the printed text to help you focus on the clinically actionable information you need everyday. [books.google.com]
ORPHA:2989 Synonym(s): - Prevalence: - Inheritance: Autosomal dominant Age of onset: Adolescent, Adult ICD-10: H11.0 OMIM: 178000 UMLS: - MeSH: - GARD: - MedDRA: - The documents contained in this web site are presented for information purposes only. [orpha.net]
It is more common for the pterygium to be present on the nasal conjunctiva and then to extend onto the surface of cornea, although it can present temporally, as well as in other locations. [nhp.gov.in]
A pterygium presents as an elevated, superficial, external ocular mass on the perilimbal conjunctiva that grows into and onto the cornea. Pterygia can vary in size, height, and rate of growth. [decisionmakerplus.net]
Entire Body System
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Outdoor Worker
Results: Thirty-eight subjects (20.4%) were outdoor workers and 148 (79.6%) were indoor workers. Outdoor workers were more likely to be male smokers and alcohol drinkers with lower family income and higher sunlight exposure than indoor workers. [link.springer.com]
Pterygium is common among outdoor workers who are daily exposed to sunlight and dust due to repeated conjunctival / corneal drying and micro-trauma Ophthalmology. 2013. [raysahelian.com]
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Severe Pain
pain that completely interferes with usual activity or sleep. [clinicaltrials.gov]
Eyes
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Corneal Edema
Corneal edema is a clinical sign of corneal disease. The condition is characterized by an increase in corneal thickness secondary to an abnormal accumulation of fluid. [decisionmakerplus.net]
Skin
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Pigmented Tumor
Ophthalmic examination reveals a pigmented tumor with clear cysts and without any visible abnormal vessels (Figure 1). Figure 2. HEx250: conjunctival mucosa seat of a malignant tumor proliferation with diffuse pigmented atypical cells. [research-journal.net]
Psychiatrical
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Withdrawn
Neovascularization in Pterygia Completed NCT00768963 Phase 1 ranibizumab;ranibizumab 37 Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of External Eye Surgery Completed NCT00344201 Phase 1 38 The Application of Fibrin Glue in Ocular Surface Diseases Withdrawn [malacards.org]
Workup
"Pterygium Workup: Imaging Studies, Procedures". emedicine.medscape.com. Archived from the original on 11 September 2016. Retrieved 15 August 2016. Mackenzie F.D., Hirst L.W., Battistutta D., Green A. (1992). [en.wikipedia.org]
"Pterygium Workup: Imaging Studies, Procedures". emedicine.medscape.com. Retrieved 15 August 2016. Mackenzie, F.D.; Hirst, L.W.; Battistutta D.; Green, A.: Risk Analysis in the Development of Pterygia. Ophthalmology. 99(7): 1056-1061, 1992. [ipfs.io]
Treatment
Helps you make optimal use of the newest drug therapies, including Anti-VEGF treatment for wet ARMD and bevacizumab treatment for complications of diabetes. [books.google.com]
The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]
Treatment Aggressive lubrication treatment Topical steroids if moderate to significant inflammation exists Surgical Treatment The only effective treatment for aggressive pterygium growth or pterygia encroaching on the visual axis is surgical removal. [decisionmakerplus.net]
Treatment for a pterygium Treatment depends on the severity of the condition. [betterhealth.vic.gov.au]
Treatment depends on the size of the growth and the symptoms that it is causing. While surgery is a treatment option, it is not always necessary. [nvisioncenters.com]
Prognosis
[…] non-cancerous) and in most cases, the condition can be resolved by surgical removal Please find comprehensive information on Pterygium regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis [dovemed.com]
Melanoma Malignant tumor often detected when small size so prognosis is usually favorable. Nevus Benign tumor that classically remains stable. Can lead to reduced visual acuity. Can transform into melanoma. [isoo.org]
With surgery, it is impossible to guarantee clear margins—a feature required for the best prognosis. The greater the amount of tissue removed to ensure clear margins, the greater the potential for long-term disruption of the ocular surface. [reviewofoptometry.com]
Prognosis The visual and cosmetic prognosis following pterygium excision is good. [emedicine.medscape.com]
Etiology
The most widely recognized etiologic factor is ultraviolet radiation, which leads to degeneration of the conjunctiva. However, pterygium was recently found to have several tumor-like characteristics. [nature.com]
Cumulative genetic damage from chronic UV exposure was speculated to be a shared etiology between pterygia and preneoplastic diseases [ 10 ]. The current standard of care is wide local excision, followed by cryotherapy to the margins. [research-journal.net]
Etiology and Pathogenesis There is a host of theories attempting to explain the pathogenesis of a pterygium; however, the etiology has yet to be determined. [aao.org]
Symptoms * None to dryness and discomfort Signs * Local saucer-like depression in the peripheral cornea * May be associated scarring and vascularization * Epithelium intact Etiology * Localized dryness and desiccation * Loss of stromal hydration causes [yooying.com]
There is a certain dose-effect correlation between ultraviolet ray exposure and the etiology of pterygium. Questions Q. i have been researching online for alternatives to pterygium surgery. [raysahelian.com]
Epidemiology
Ophthalmic Epidemiology". Ophthalmic Epidemiology. 1 (2): 67–84. CS1 maint: Multiple names: authors list ( link ) Lee G., Hirst L.W., Sheehan M. "1999 Knowledge of Sunlight effects on the eyes and protective behaviors in adolescents". [en.wikipedia.org]
Ophthalmic Epidemiology 1999; 6(3): 219–228. PubMed CrossRef Google Scholar 6. Tan DTH, Chee SP, Dear KBG, Lim ASM. [link.springer.com]
Epidemiological studies correlate with the UV dose received throughout life, either by geographic cause, or professional sports; sunglasses or even hats are useful for prevention. [barraquer.com]
Ophthalmic Epidemiology. Ophthalmic Epidemiology. 1(2):67-84, 1994. Lee, G.; Hirst, L.W.; Sheehan, M.: Knowledge of Sunlight effects on the eyes and protective behaviors in adolescents. Ophthalmic Epidemiology. 6(3): 171–180, 1999. [ipfs.io]
EPIDEMIOLOGY Global Information The prevalence of pterygium was found to be 10.2% in the world, with highest prevalence in low altitude regions (Liu et al, 2013). [aao.org]
Pathophysiology
Pterygium pathophysiology. See Image Library for figure. Pterygium comes from the Greek word meaning wing, pterygos. Pterygium is a triangular fibrovascular growth that extends from the conjunctiva toward the cornea. [aao.org]
The pathophysiology of pterygium is characterized by elastotic degeneration of collagen and fibrovascular proliferation, with an overlying covering of epithelium. [emedicine.medscape.com]
Congenital Neutropenia Syndromes Pathophysiology • Mutations in the ELA-2 / elastase protein leads to cytoplasmic accumulation of non-functional protein, disturbance of cellular Pathophysiology p trafficking and activation of unfolded protein response [de.slideshare.net]
Once the diagnosis is made, proper management must address both the pathophysiology of the disease and ocular surface dysfunction. In terms of medical therapy, chronic steroid-sparing immunomodulators are the mainstay. [webeye.ophth.uiowa.edu]
Prevention
Once the pterygium has been surgically removed, medication may be used to aid in healing and prevent recurrence. [uvahealth.com]
Once the pterygium has been surgically removed, medication may be used to aid in healing and prevent recurrence. Prevention To help reduce your chance of pterygium: Wear dark glasses with UV protection to shield the eyes from sun, dust, and wind. [winchesterhospital.org]
Preventing Pterygium The best method of preventing pterygium is to regularly wear UV 400 rated sunglasses when outdoors in sunny conditions. [doctor-hill.com]
Prevention These diseases are more common in tropical countries and especially in mountain areas. [barraquer.com]