All the affected members present autoantibodies against various antigens. In nine patients immunofluorescence revealed antibody coated bacteria in urine specimens. [ncbi.nlm.nih.gov]

• Turkish

  The Na /glucose cotransporter gene SGLT2 ( SLC5A2 ) was analyzed in a Turkish patient with congenital isolated renal glucosuria. [doi.org]

• Macula

  The rise in glucose uptake contributes to hyperglycaemia and induces glomerular hyperfiltration by increasing sodium and water reabsorption in the proximal tubule that, in turn, modifies urine flux at the macula densa. [ncbi.nlm.nih.gov]

• Glycosuria

  Further characterization revealed osmotic diuresis due to massive glycosuria without hyperglycemia. Glycosuria reduced substantially postpartum, from approximately 100 to approximately 30 g/1.73 m2 per day. [ncbi.nlm.nih.gov]

• Candida

  One individual, who was compound heterozygous for mutations in the SLC5A2 gene suffered from severe urogenital candida infections and postprandial hypoglycemia. [ncbi.nlm.nih.gov]

Though renal glycosuria is a benign condition, mistaken diagnosis for diabetes mellitus puts patients at risk of hypoglycaemia due to treatment. [ncbi.nlm.nih.gov]

Treatment is directed at the underlying tubular disease condition. [doctor.ndtv.com]

Treatment of hyperglycaemia: The unique mechanism of SGLT2 inhibitors means they can probably be used alongside other hypoglycaemic treatments. [revistanefrologia.com]

CLOSE Medical Disclaimer The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. [diseaseinfosearch.org]

You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments. [rarediseases.info.nih.gov]

Prognosis of benign renal glycosuria is excellent and reversible. Acute interstitial nephritis (AIN) is one of the main causes of acute renal failure and may often result in tubular dysfunction. [ncbi.nlm.nih.gov]

Primary renal glucosuria has been considered a ‘non-disease’ with an excellent prognosis. [doi.org]

Our data provide the first direct evidence of an etiologic role for the sodium/glucose cotransporter type 2 in the pathogenesis of renal glucosuria. [doi.org]

Etiologically, renal glycosuria is of 3 types-benign renal glycosuria, glycosuria with diabetes mellitus (including gestational diabetes) and tubular defects (Fanconi syndrome). Prognosis of benign renal glycosuria is excellent and reversible. [ncbi.nlm.nih.gov]

Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. [icd10data.com]

It gives compreensive coverage of the epidemiology, aetiology, and mechanism of disease, as well as clear, unambiguous coverage of the diagnosis, practical management and prevention of the entire spectrum of medical disorders. [books.google.de]

From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. [books.google.de]

Understanding the pathophysiology of type 2 diabetes is a dynamic process: When new pathophysiological concepts arise, new potential therapeutic tools are found. [revistanefrologia.com]

Hanley ME, Bone RC: Acute respiratory failure: Pathophysiology, causes and clinical management. Postgrad Med 1986;79:166–176. [doi.org]

Pathophysiology Blood is filtered by millions of nephrons, the functional units that comprise the kidneys. In each nephron, blood flows from the arteriole into the glomerulus, a tuft of leaky capillaries. [dictionnaire.sensagent.leparisien.fr]

Abstract Under physiological conditions, the kidneys contribute to glucose homoeostasis by producing glucose by gluconeogenesis and preventing glucose loss in urine. [ncbi.nlm.nih.gov]

It gives compreensive coverage of the epidemiology, aetiology, and mechanism of disease, as well as clear, unambiguous coverage of the diagnosis, practical management and prevention of the entire spectrum of medical disorders. [books.google.de]

[…] sudden cardiac death - guidance (IPG603) Source: National Institute for Health and Care Excellence - NICE - 20 December 2017 Evidence-based recommendations on subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac [evidence.nhs.uk]