RESULTS: The family had 6 members with temporal lobe epilepsy. Age at seizure onset ranged from 8 to 13 years. [ncbi.nlm.nih.gov]

Pathways for Benign Familial Mesial Temporal Lobe Epilepsy GO Terms for Benign Familial Mesial Temporal Lobe Epilepsy Sources for Benign Familial Mesial Temporal Lobe Epilepsy [malacards.org]

Homepage Rare diseases Search Search for a rare disease Benign familial mesial temporal lobe epilepsy Disease definition Benign familial mesial temporal lobe epilepsy is a rare epilepsy characterized by seizures with viscerosensory or experential auras [orpha.net]

Factors that may contribute to these seizures include screen brightness, sleep deprivation, fatigue, fever and short distance from the screen. [aafp.org]

It is best to let a child rest during these times, remain well nourished, and have judicious control of fever. [childneurologyfoundation.org]

CSF examination is recommended in children (except for infants younger than 6 months of age) and adults only when cerebral infection is suspected or fever is present which cannot be explained by an extracranial origin (Hirtz et al. 2000; Beghi 2008). [slideshare.net]

At discharge patient’s examination was normal except for persistence of fever and oral prednisone was started but he developed a cerebral venous sinus thrombosis. [docksci.com]

Depression and immunity: Inflammation and depressive symptoms in multiple sclerosis. Immunol Allergy Clin North Am. 2009;29:309–20. PubMed CrossRef PubMedCentral Google Scholar 74. Kahl KG, Kruse N, Faller H, et al. [link.springer.com]

[…] that are not clearly antibody-mediated but have histopathologic evidence of cellular inflammation. [docksci.com]

Hoarseness is a side effect. Multiple diets exist that can help control seizures. The ketogenic diet is a strict meal plan consisting primarily of fats and oils and complete elimination of carbohydrates. [childneurologyfoundation.org]

Temporal lobe seizures are often accompanied by strange sensations, sweating, flushing, vertigo, epigastric sensations, taste, and hearing of sounds or melodies, nausea, hallucinations or feelings of déjà vu. [epilepsyqueensland.com.au]

[…] and perceptual phenomena, as well as autonomic symptoms is possible in this epilepsy syndrome: déjà vu, jamais vu, “stranger behind the back”, feeling of detachment from oneself, sensation of enlightenment, extreme pleasure, fear and dread, anxiety, nausea [doctorstrizhak.com]

Symptoms are myriad but tend to localize around the eyes (glassy-eyed, “drugged”, dazed, far-away look), the mouth (lip-smacking, drooling, gurgling) and the abdomen (nausea, vomiting, epigastric sensation). 8 Most seizures last for several minutes and [aafp.org]

Children with these types of seizures can present with pallor, visual changes, vomiting, nausea, dilated pupils, or fainting spells. The eyes and head can be deviated towards one direction and consciousness can be impaired. [childneurologyfoundation.org]

however, be minimal or absent Transient global amnesia Sudden onset of isolated anterograde and retrograde amnesia for usually 2–8 h Panic attack Abrupt onset with intense feeling of fear, no loss of consciousness, autonomic features (tachycardia, nausea [slideshare.net]

Microanatomy Musculoskeletal Neuroanatomy Neurology Neuromuscular Neurosurgery Nursing Nutrition Obstetrics Occupational Therapy Oncology Opthamology Optometry Orthodontics Orthopedics Otolaryngology Paramedic Passive Care Pathology Pathoma Pediatrics Periodontics [brainscape.com]

CONCLUSIONS: Our data suggest the existence of a novel locus for benign familial mesial temporal lobe epilepsy on chromosome 3q26. [ncbi.nlm.nih.gov]

Scott Baraban, Edward Cooper, Donald Schomer, and Robert Sloviter for their useful suggestions and critical review. [nejm.org]

Thus, the finding of at least two MTLE patients in one family is suggestive of familial MTLE. [neupsykey.com]

Age at seizure onset ranged from 8 to 13 years. Five patients had epigastric auras often associated to oro-alimentary automatic activity, 3 patients presented loss of contact, and 2 experienced secondary generalizations. [ncbi.nlm.nih.gov]

It is defined as at least 24 months of seizure freedom with or without antiepileptic medication. [orpha.net]

The frequent occurrence of seizures refractory to antiepileptic drug treatments is of great concern. [books.google.com]

Five patients had epigastric auras often associated to oro-alimentary automatic activity, 3 patients presented loss of contact, and 2 experienced secondary generalizations. [ncbi.nlm.nih.gov]

Homepage Rare diseases Search Search for a rare disease Benign familial mesial temporal lobe epilepsy Disease definition Benign familial mesial temporal lobe epilepsy is a rare epilepsy characterized by seizures with viscerosensory or experential auras [orpha.net]

Some of the reported families, grouped on the basis of a specific aura, may represent an interesting subgroup on whom to focus future linkage studies. [scipers.com]

There are several reports of patients with LGI1 mutations with other partial seizures including receptive aphasia (loss of speech comprehension) and visual auras. [epilepsygenetics.net]

seizures Generalized seizures affect both the cerebral hemispheres right from the onset of the seizure. [ispub.com]

Grand mal seizures can be primarily generalized seizures or can evolve from focal seizures (bilateral convulsive seizures, old term: secondarily generalized seizures). [slideshare.net]

Symptoms vary from small absence seizures, where the person is unresponsive for a few seconds or minutes, to generalized seizures, with possible falling, convulsions and repetitive behavior. [neurosurgery.ucla.edu]

Often, these children present for medical attention because of the high association (50 percent) with generalized seizures, which tend to be nocturnal or early-morning episodes. [aafp.org]

Ward N, Evanson J, Cockerell OC (2002) Idiopathic familial temporal lobe epilepsy with febrile convulsions. Seizure 11:16–19 PubMed CrossRef Google Scholar 9. [link.springer.com]

Febrile seizures A subset of children with complex febrile convulsions appears to be at risk of developing temporal lobe epilepsy in later life. [emedicine.medscape.com]

convulsions Continuous seizures (status epilepticus) Generalized status epilepticus Generalized tonic-clonic status epilepticus Generalized Absence/ Petit Mal status epilepticus Clonic status epilepticus Tonic status epilepticus Myoclonic status epilepticus [ispub.com]

Factors prognostic of unprovoked seizures after febrile convulsions. N Engl J Med. 1987;316:493–8. 4. Berg AT, Shinnar S. Complex febrile seizures. Epilepsia. 1996;37:126–33. 5. [aafp.org]

hypoxia-ischemia, intracranial hemorrhage, infections, and metabolic derangements such as hypocalcemia) to remote symptomatic causes (e.g., cerebral dysgenesis and inborn errors of metabolism) to idiopathic, genetically determined epilepsies (e.g., [clinicalgate.com]

Introduction: Arteriovenous malformation (AVM) is the most common cause of intracranial hemorrhages in children. Mortality can be as high as 25% 1. [docksci.com]

[…] in adolescence or early adulthood and good prognosis. [orpha.net]

[…] in adolescence or adulthood Often prominent ictal déjà vu, dreamlike state, fear, and nausea, with simple partial and complex partial seizures and infrequent secondary generalization. [slideshare.net]

EEG showed focal slow waves and epileptic abnormalities on temporal regions in 1 patient and was normal in the other affected individuals. MRI was normal in all temporal lobe epilepsy patients. [ncbi.nlm.nih.gov]

Inter-ictal EEG Usually normal (half the cases) or with mild focal slow waves (28%) or sparse sharp- and slow-wave complexes localized in the temporal region and usually unilateral (22%). Sleep may activate epileptiform abnormalities. [epilepsy.com]

Inter-ictal EEG is often abnormal with focal slow waves and spikes over the affected temporal lobe. Ictal EEG demonstrates 4 to 7 Hz rhythmic activity or fast spiking in the leads over the affected temporal lobe. [doctorstrizhak.com]