For those children, the first sign is often fatigue. Because red blood cells deliver oxygen to every part of the body, when there aren't enough red blood cells to go around, tiredness sets in. [ucsfbenioffchildrens.org]

Complications of Fanconi anemia Fanconi anemia may lead to: Delayed growth or development Infection, especially pneumonia, chickenpox, and hepatitis Fatigue Digestive problems Certain cancers Death Diagnosis of Fanconi anemia Fanconi anemia usually is [stanfordchildrens.org]

Anemia The most common symptom of all types of anemia is fatigue (tiredness). Fatigue occurs because your body doesn't have enough red blood cells to carry oxygen to its various parts. [hoacny.com]

Complications of Fanconi anemia Fanconi anemia may lead to: Delayed growth or development Infection, especially pneumonia, chickenpox, and hepatitis Fatigue Digestive problems Certain cancers Death Diagnosis Diagnosis Diagnosis of Fanconi anemia Fanconi [childrensnational.org]

About 60–75% of people have congenital defects, commonly short stature, abnormalities of the skin, arms, head, eyes, kidneys, and ears, and developmental disabilities. [en.wikipedia.org]

[…] tubular, stiff, hyperextensible Radii - Absent or hypoplastic (only with abnormal thumbs [ie, terminal defects]), absent or weak pulse Hands - Clinodactyly, hypoplastic thenar eminence, 6 fingers, absent first metacarpal, enlarged abnormal fingers, short [emedicine.medscape.com]

Additional skeletal abnormalities include extra fingers (polydactyly); fifth fingers that are permanently curved toward the ring finger (clinodactyly); short fingers; absence of one of the bones of the hand (first metacarpal); and malformation of the [web.archive.org]

Pseudotumor cerebri (PC) is a clinical syndrome characterized by increased intracranial pressure with a normal cerebrospinal fluid cell count and protein level in the absence of a space-occupying lesion or apparent obstruction to the cerebrospinal fluid [ncbi.nlm.nih.gov]

They may exhibit symptoms such as: Unexplained fatigue Recurrent colds or viral infections Recurrent nosebleeds Easy bruising Blood in the stool or urine Shortness of breath Poor growth / short stature In rare cases, symptoms do not occur until early [cincinnatichildrens.org]

Nosebleeds or easy bruising may be a first sign of the disease. Blood tests may reveal a low white cell, red cell or platelet count or other abnormalities. [fanconi.org]

Medical problems associated with pancytopenia include pale skin, easy bleeding/poor clotting, easy bruising, fatigue, weakness, and shortness of breath. All of these problems are common in FA. [forgottendiseases.org]

Early signs and symptoms may include the following: Extreme fatigue Shortness of breath Pale skin Feeling dizzy Headaches Chest pain Frequent infections Easy bruising Nosebleeds About 60 percent of children with Fanconi anemia are born with at least one [stjude.org]

When Fanconi syndrome occurs because of cystinosis, failure to thrive and growth retardation are common. The retinas show patchy depigmentation. [merckmanuals.com]

[…] to thrive Learning disability Low birth weight Intellectual disability People with mild to moderate blood cell changes who do not need a transfusion may only need regular check-ups and blood count checks. [nlm.nih.gov]

The resulting lack of essential metabolites can cause dehydration, bone deformities, and a failure to thrive. There are treatments available that can slow or stop FS progression. FS is most often inherited. [healthline.com]

Among the more common birth defects are the following: Short stature Thumb, hand and arm anomalies Skeletal abnormalities of the hip and spine Kidney problems Skin discoloration Small head or eyes Low birth weight and failure to thrive Digestive tract [fanconicanada.org]

Affected individuals may also have overgrowth of skin on the palms of the hands and soles of the feet, excessive sweating of the palms and soles, sparse or absent hair, fragile bones, underdeveloped testes, and dental abnormalities. [web.archive.org]

Less common abnormalities may also be associated with Fanconi anemia including abnormalities of the middle ears resulting in hearing impairment (conductive hearing loss). Some individuals may have abnormally low-set, malformed outer ears (pinnae). [web.archive.org]