In one subject, infusion of IT saline resulted in faster resolution of peripheral edema. Peripheral lower extremity edema may occur in patients treated with IT infusion of hydromorphone or morphine, even at low doses. [ncbi.nlm.nih.gov]

The most common AEs were somnolence, nausea, and vomiting. All AEs were mild or moderate in severity. Doses at 400, 600, and 800 mcg were associated with nausea and vomiting, requiring pharmacologic intervention. [ncbi.nlm.nih.gov]

The most common AEs were somnolence, nausea, and vomiting. All AEs were mild or moderate in severity. Doses at 400, 600, and 800 mcg were associated with nausea and vomiting, requiring pharmacologic intervention. [ncbi.nlm.nih.gov]

Gaskey NJ, Ferriero L, Pournaras L, Seecof J "Use of fentanyl markedly increases nausea and vomiting in gynecological short stay patients." AANA J 54 (1986): 309-11 36. [web.archive.org]

A 42-year-old man with lymphoma was started on transdermal fentanyl therapy while hospitalized for chronic abdominal pain. The patient was last seen awake 1.3 h prior to being found apneic and cyanotic. [ncbi.nlm.nih.gov]

Magnetic Resonance Imaging (MRI) with diffuse weighed scan, duplex ultrasound for deep vein thrombosis, carotid artery Doppler, electroencephalography (EEG), and trans-thoracic echocardiography were all normal. [ncbi.nlm.nih.gov]

Fentanyl, fentanyl analogs and other novel synthetic opioids are all full agonists of varying potencies at the μ-opioid receptor, leading to typical clinical effects of miosis and respiratory and central nervous system depression. [ncbi.nlm.nih.gov]

[…] subcutaneous tissue disorders Erythema 1 The following adverse reactions occurred in adult and pediatric patients with an overall frequency of 1% and are listed in descending frequency within each System/Organ Class: Cardiac disorders: cyanosis Eye disorders: miosis [rxlist.com]

Kappa 1: Spinal analgesia and miosis. Kappa 2: Dysphoria and psychotomimesis. Kappa 3: Supraspinal analgesia. Chronic opioid users develop tolerance to the analgesic and euphoric effects, but not to the respiratory depression effects. [acilbook.com]

Fentanyl may also produce other signs and symptoms characteristic of narcotic analgesics including euphoria, miosis, bradycardia and bronchoconstriction. [web.archive.org]

[…] specific receptor binding sites in the CNS and other tissues; opiate receptors are concentrated in the limbic system, thalamus, striatum, hypothalamus, midbrain, and spinal cord. f Agonist activity at the opiate μ- or κ-receptor can result in analgesia, miosis [drugs.com]

Transient blindness in a preeclamptic patient secondary to cerebral edema. Hawaii Med J. 1996; 55 :116–7. [ PubMed ] [ Google Scholar ] 7. Williams K, McLean C. Maternal cerebral vasospasm in eclampsia assessed by transcranial Doppler. [ncbi.nlm.nih.gov]

Transient blindness in a preeclamptic patient secondary to cerebral edema. Hawaii Med J 1996;55:116-7. [ PUBMED ] 7. Williams K, McLean C. Maternal cerebral vasospasm in eclampsia assessed by transcranial Doppler. [dx.doi.org]

Although intrathecal opioids are safe for both the mother and fetus; some unusual complications such as dysphagia alone or associated with facial numbness, aphasia, have been reported. [ncbi.nlm.nih.gov]

Communities say their budgets are being strained by the additional needs — for increased police and medical care, for widespread naloxone distribution and for a stronger foster care system that can handle the swelling number of neglected or orphaned children [web.archive.org]

Manifestations Signs and Symptoms Fentanyl Analgesics, Opioid Narcotics Central Nervous System Depressants Physiological Effects of Drugs Analgesics Sensory System Agents Peripheral Nervous System Agents Adjuvants, Anesthesia Anesthetics, Intravenous [clinicaltrials.gov]

A 79 year old male patient, scheduled for hernia repair, and with a preoperative physical examination of slight hand tremor, received a bolus of 100 mcg (1.2 mcg/kg) fentanyl as primary agent for induction. [ncbi.nlm.nih.gov]

Others have estimated an incidence of 4 in 100,000 per year ( Katusic 1991 ; Rappaport 1994 ) for trigeminal neuralgia, and of 12.6 per 100,000 person‐years for trigeminal neuralgia and 3.9 per 100,000 person‐years for PHN in a study of facial pain in [doi.org]