As the toxicity of organophosphates is non-specific, it has caused ill health and death in man, and has contributed to adverse ecological effects.This book, written by recognised experts, studies and presents information in a manner that basic scientists [books.google.com]

Fourteen kestrels were presented with live sparrows exposed previously to perches containing Rid-A-Bird 1100 solution (11% fenthion active ingredient). Eleven kestrels died within twenty-four h after consuming one fenthion-exposed sparrow. [ncbi.nlm.nih.gov]

[…] linkedin twitter youtube instagram logo-thumbprint logo-text cmha-logo cmha-logo imagine-canada Year: 2002 Source: Human and Experimental Toxicology, v.21, no.1, (January 2002), p.49-54 SIEC No: 20020897 Two cases of severe fenthion intoxication are presented [suicideinfo.ca]

Twelve hours after she presented, a breathing tube was inserted and she was placed on a ventilator. [poison.org]

Abstract Two cases of severe fenthion intoxication are presented. The first is a case of a psychiatric patient who attempted suicide with ingestion of the compound, and the second case was of a child exposed to the chemical agent by air spraying. [safeaccess.unboundmedicine.com]

• Unconsciousness

  Very high doses may result in unconsciousness, incontinence, and convulsions or fatality. ‏ الصفحة 233 - US Environmental Protection Agency. [books.google.com]

  Initial assessment of the unconscious patient Initial assessment involves checking airway, breathing and circulation. [ccforum.biomedcentral.com]

  Written informed consent was taken from each patient, or their relatives (for patients unconscious or under the age of 16), in their own language. Cohort study. [academic.oup.com]

• Sepsis

  Six days after the child ingested the malathion she remained on a ventilator with possible sepsis or pneumonia but had improved to the point that both the atropine and pralidoxime were discontinued. [poison.org]

• Respiratory Distress

  This togetherly is associated with Acute Respiratory Distress Syndrome (ARDS). Identification of poisoning is done on the basis of symptoms shown by patients while perfect diagnosis requires biochemical analysis. [sciencepubco.com]

• Nausea

  الصفحة 216 - Symptoms of acute exposure to organophosphate or cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination, headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision [books.google.com]

  Symptoms of poisoning: Mild intoxication causes headache, blurred vision, weakness, swating, mild chest pain, nausea and vomiting. Severe intoxication causes cyanosis, muscular twitching, spasms, miosis and respiratory paralysis. [animalhealth.bayer.co.za]

• Muscle Twitch

  There can be many symptoms, though they may not be as clear-cut in children as they are in adults: blurred vision; tearing and sweating; loss of bowel and bladder control; difficulty breathing, as the airway may fill with fluid; tremors, muscle twitching [poison.org]

• Muscle Cramp

  Symptoms such as hyper-salivation, convulsions, respiratory failure, ataxia, slurred speech, miosis, muscle cramping suggest about poisoning. To access Organophosphorus poisoning, it is necessary to analyze biological samples mostly blood and urine. [sciencepubco.com]

• Blurred Vision

  الصفحة 216 - Symptoms of acute exposure to organophosphate or cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination, headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision [books.google.com]

  Symptoms of poisoning: Mild intoxication causes headache, blurred vision, weakness, swating, mild chest pain, nausea and vomiting. Severe intoxication causes cyanosis, muscular twitching, spasms, miosis and respiratory paralysis. [animalhealth.bayer.co.za]

  There can be many symptoms, though they may not be as clear-cut in children as they are in adults: blurred vision; tearing and sweating; loss of bowel and bladder control; difficulty breathing, as the airway may fill with fluid; tremors, muscle twitching [poison.org]

• Lacrimation

  Clinical features: Muscarinic: DUMBBELS – Diarrhoea, urination, miosis, bronchorrhoea, bronchospasm, emesis, lacrimation, salivation. Plus bradycardia and hypotension. [lifeinthefastlane.com]

• Withdrawn

  It returns to normal following successful oxime therapy and is used to monitor progress when oxides are withdrawn. Mixed Cholinesterase test: Currently not validated but involves mixing patient serum and a control serum in a 50:50 ratio. [lifeinthefastlane.com]

• Distractibility

  Supporter of FOAMed, tox, sim, ultrasound and any other project that can distract me for 5 seconds ..... oh look squirrel. | @doctorneillong | + Neil Long | LinkedIn Reader Interactions [lifeinthefastlane.com]

• Headache

  الصفحة 216 - Symptoms of acute exposure to organophosphate or cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination, headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision [books.google.com]

  Symptoms of poisoning: Mild intoxication causes headache, blurred vision, weakness, swating, mild chest pain, nausea and vomiting. Severe intoxication causes cyanosis, muscular twitching, spasms, miosis and respiratory paralysis. [animalhealth.bayer.co.za]

  Organophosphates and carbamates often have a hydrocarbon solvent that causes a headache and dizziness, this in and of itself does not indicate organophosphate poisoning. Toxicokinetics: Rapidly absorbed following ingestion. [lifeinthefastlane.com]

• Seizure

  The serum fenthion value reached its maximal level of 0.66μg/ml at the time of a seizure that occurred 20 hours after exposure, and the half-life of fenthion was 11 hours. [jstage.jst.go.jp]

  Carbamates have less CNS distribution Undergo hepatic metabolism prior to urinary excretion Elimination of some organochlorines may take weeks to months Resuscitation: Potential life threats include: Coma – intubate and ventilate Hypotension Seizures [lifeinthefastlane.com]

  […] be many symptoms, though they may not be as clear-cut in children as they are in adults: blurred vision; tearing and sweating; loss of bowel and bladder control; difficulty breathing, as the airway may fill with fluid; tremors, muscle twitching, and seizures [poison.org]

• Tremor

  الصفحة 216 - Symptoms of acute exposure to organophosphate or cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination, headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision [books.google.com]

  There can be many symptoms, though they may not be as clear-cut in children as they are in adults: blurred vision; tearing and sweating; loss of bowel and bladder control; difficulty breathing, as the airway may fill with fluid; tremors, muscle twitching [poison.org]

  Nicotinic: Fasiculations, tremor, weakness, respiratory muscle paralysis, tachycardia (can also be secondary to hypoxia and hypotension) and hypertension. [lifeinthefastlane.com]

• Dizziness

  الصفحة 216 - Symptoms of acute exposure to organophosphate or cholinesterase-inhibiting compounds may include the following: numbness, tingling sensations, incoordination, headache, dizziness, tremor, nausea, abdominal cramps, sweating, blurred vision [books.google.com]

  Organophosphates and carbamates often have a hydrocarbon solvent that causes a headache and dizziness, this in and of itself does not indicate organophosphate poisoning. Toxicokinetics: Rapidly absorbed following ingestion. [lifeinthefastlane.com]

• Slurred Speech

  Symptoms such as hyper-salivation, convulsions, respiratory failure, ataxia, slurred speech, miosis, muscle cramping suggest about poisoning. To access Organophosphorus poisoning, it is necessary to analyze biological samples mostly blood and urine. [sciencepubco.com]

Deltamethrin was found to have a faster degradation rate than fenthion, leaving no traces on olives 18 days after treatment. Fenthion, on the contrary, was still present on the drupes at harvest (28 days after the treatment). [link.springer.com]

Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. [drugs.com]

These are lower-toxicity pesticides used variously for home and garden pest control, veterinary treatments, agricultural pest control, and even treatment of head lice. [poison.org]

[…] of moderately to severely OP poisoned patients, are the hallmarks of treatment. [18] More prospective data are required. [emedicine.medscape.com]

The use of BuChE assays for monitoring the effect of pralidoxime treatment is unlikely to be clinically useful. [academic.oup.com]

The rapid and effective stabilisation and treatment of pesticide-poisoned patients on their admission should reduce the number of early deaths, improve the prognosis for surviving patients over the next few days, and reduce the number and severity of [ccforum.biomedcentral.com]

Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates [books.google.com]

The pathophysiology is not well understood and theories range from inadequate pralidoxime dosing or redistribution from lipid stores. [lifeinthefastlane.com]

However, BuChE inhibition is not relevant to the pathophysiology of OP poisoning, and its usefulness would need to be linked to either clinical features or an association with AChE inhibition (if AChE is a good marker, see below). [academic.oup.com]

Preventing Poisoning In The Home A few basic fact and hints regarding preventing poisoning with medicines and chemicals around the ho... [poisons.co.nz]

Possible future interventions include neuroprotective agents used to prevent nerve damage and bioscavengers aimed to prevent AChE inhibition by nerve agents or OP. [emedicine.medscape.com]

Severe poisonings can be difficult to treat and recovery can be prolonged, making prevention of poisoning very important. [poison.org]

Pralidoxime is required to prevent ‘ageing’ and also to reverse neuromuscular blockade with organophosphates only ( not carbamates). [lifeinthefastlane.com]