Presentation
She presented with erythematous maculopapules on the face and excoriated papules and lichenified plaques on the trunk and forearms, which had been present for two years. [ncbi.nlm.nih.gov]
Patients present with red teeth and immediatephotosensitivy during infancy. [de.slideshare.net]
Case Report A 65-year-old male presented to the emergency department with a painful right wrist, subsequent to a fall ten days earlier on to his outstretched hand. [ijcasereportsandimages.com]
Thimerosal, a former component merthiolate and currently present in some drugs and vaccines. [tabletsmanual.com]
Improve your interpretation of presenting symptoms with 38 new topics and 40 new images in the Differential Diagnosis section, and optimize patient care with more than 250 new figures and tables. [books.google.de]
Entire Body System
- Leg Swelling
Veins in the lower legs fail to return blood efficiently, causing pooling of blood and fluid buildup and swelling. This swelling leads to skin irritation, especially around the ankles. [webmd.com]
Cardiovascular
- Hypertension
Delivery Models Health Care Economics, Insurance, Payment Health Care Policy Health Care Quality Health Care Reform Health Care Safety Health Care Workforce Health Disparities Health Informatics Health Policy Hematology History of Medicine Humanities Hypertension [jamanetwork.com]
Systemic steroids should be used cautiously in patients with diabetes mellitus, psychotic disorders, uncontrolled hypertension, or infections such as tuberculosis or herpes. [aafp.org]
IFNalphaAtopic dermatitis is considered a disease in which a Th2 pattern predominates, especially early on.Th2 cytokines are IL4, IL5, IL6, IL10, IL1346) An elderly gentleman with a history of hypertension and a thymoma, presents to theEmergency Room [de.slideshare.net]
Skin
- Dry Skin
Typical signs & symptoms include Red, bumpy, itchy rash Dry skin Burning or stinging Hives Blisters A severe allergic reaction is known as anaphylaxis. Symptoms of anaphylaxis are breathing difficulty, swollen face and/or eyes, and confusion. [northstardermatology.com]
You’ll gradually notice: Dry, chapped skin. With repeat exposure, patches of itchy, red, swollen, and scaly skin develop. [susongderm.com]
Note the following: Dry air: Dry air renders the skin more susceptible to cutaneous irritants. Sufficiently dry air alone may provoke irritant contact dermatitis. [dermaamin.com]
Sufficiently dry air alone may provoke irritant contact dermatitis. Most cases of winter itch are a result of dry skin from the drier air found during sustained periods of cold weather. [emedicine.medscape.com]
- Pruritus
Contact Dermatitis 5:175–177 PubMed CrossRef Google Scholar Braun-Falco O, Plewig G, Wolff HH (1996) Pruritus, Prurigokrankheiten, Artefakte, neurologische Erkrankungen. [link.springer.com]
Pathophysiology of pruritus. In: Bieber T, Leung DYM, editors. Atopic dermatitis. New York: Marcel Dekker, Inc; 2002. pp. 183-216. [inspectapedia.com]
Pain, burning, stinging, or discomfort exceeding pruritus early in the clinical course occur. [dermaamin.com]
Pruritus is the overriding symptom. Latex allergic reactions range from pruritus to erythematous, weeping lesions. 8 A concurrent irritant contact dermatitis from nonlatex chemicals used in glove production may also develop. [aafp.org]
A common example is fiberglass, which may produce pruritus with minimal visible inflammation in susceptible individuals. Many plant leaves and stems bear small spicules and barbs that produce direct skin trauma. [emedicine.medscape.com]
- Hyperkeratosis
[…] affected body part Demarcated areas from the normal skin Cracking\chapping of the affected body part Fissuring Bleeding Pustular skin changes Itching\burning with or without visible skin changes Chronic effects Repeated exposures required Skin dryness Hyperkeratosis [accessmedicine.mhmedical.com]
Frictional Irritant Contact Dermatitis Results from repeated low-grade frictional trauma Plays adjuvant role in ACD and ICD Characterized by hyperkeratosis, acanthosis, and lichenification, often progressing to hardening, thickening, and increased [slideshare.net]
The histology of chronic irritant contact dermatitis is one of hyperkeratosis with areas of parakeratosis, moderate-to-marked epidermal hyperplasia (acanthosis), and elongation of the rete ridges. [dermaamin.com]
The clinical features include redness and dryness followed by a thickening of the skin called hyperkeratosis. The threshold varies again between individuals. [wsiat.on.ca]
Mutations in Keratins 1&10 are associatedwith epidermolytic hyperkeratosis ande Unna-thost. Mutations in keratins 1&9 are associated withepidermolytic palmoplantar keratoderma. [de.slideshare.net]
- Chronic Dermatitis
Mechanical friction from sanding down these materials often causes chronic dermatitis on the hands and the resulting dust causes dermatitis on the face. [wsiat.on.ca]
CHRONIC DERMATITIS Emollients Topical agents such as petrolatum (Vaseline) provide an occlusive film over inflamed skin, decrease fissuring, and reduce evaporation. [aafp.org]
Psychiatrical
- Fear
As for me, after finding these pictures I am-scrayed, for fear of a total breakfast reversal (TBR). Fiberglass dermatitis isn't a disease. It's just a condition, caused by little glass shards stuck in your skin. [phil-are-go.blogspot.com]
Another Vestas employee who asked to remain anonymous for fear of retribution said, like Estes, he was exposed to epoxy resin while working at the Windsor facility between February 2008 and August. [windaction.org]
- Euphoria
A group of firemen, who were exposed to isocyanates, reported numerous neurological symptoms such as: euphoria, headache, difficulty concentrating, poor memory, and confusion. [healthyhouseinstitute.com]
- Delusion
Psychogenic itch is related to psychologic abnormalities e.g., itch in obsessive compulsive disorders, depression, and delusions of parasitosis. [inspectapedia.com]
Neurologic
- Dizziness
Blehm, the Colorado State University professor, said health risks and dangers involved with the material depends on the chemicals used, but common health risks include dermatitis, dizziness, sleepiness, liver damage, kidney damage, blisters, chemical [windaction.org]
Health effects included: eye, nose and throat irritation, cough, headache, dizziness, bronchopneumonia, pulmonary edema, asthma, dermatitis, rhinitis, conjunctivitis, and allergy. [healthyhouseinstitute.com]
In high concentrations, narcosis is produced with symptoms of headache, nausea, light-headedness, vomiting, dizziness, incoordination, and unconsciousness. Ketones are volatile and flammable. [osha.gov]
Workup
(See Workup ). The definitive treatment of irritant contact dermatitis is the identification and removal of any potential causal agents. [emedicine.medscape.com]
Treatment
Just as Ototoxicity is a well-known hazard of parenteral neomycin administration, so has deafness been reported after almost any form of local treatment, including treatment of skin infections and burns... [books.google.com]
The treatment is to avoid the causative substance and allow the skin to heal using gentle cleansers, moisturizers and possibly cortisone creams. [rejuvadoc.com]
They can try to identify the cause and suggest appropriate treatments. [nhs.uk]
Treatments may include moisturizers, lotions, baths, cortisone creams that relieve swelling, and antihistamines, which relieve itching. [icdlist.com]
Topical zinc pyrithione is generally recognized as a safe and effective treatment for reduction in the symptoms associated with dermatitis. [dermaharmony.com]
Prognosis
Page 15 - Hogan DJ, Dannaker CJ, Maibach HI (1990) The prognosis of contact dermatitis. [books.google.com]
Prognosis 9.1. Good if there are no secondary complications and the person can avoid the irritant [mindmeister.com]
Camarasa JG ; Romaguera C ; Serra-Baldrich E ; Vilaplana J Contact Dermatitis. 1993 Prognosis of occupational contact dermatitis in New South Wales, Australia. [research.johas.go.jp]
Prognosis Prognosis is good for nonatopic individuals in whom irritant contact dermatitis (ICD) is diagnosed and managed promptly. [emedicine.medscape.com]
The prognosis is very good but scarring can occur. An example would be exposure to wet cement causing a “cement burn”. [wsiat.on.ca]
Etiology
[…] proximal) phalanges of one or more fingers Frequent attacks affecting all phalanges of most fingers Page 97 - Imokawa G, Abe A, Jin K, Higaki Y, Kawashima M, Hidano A (1991) Decreased levels of ceramides in stratum corneum of atopic dermatitis: an etiologic [books.google.com]
Etiology 7.1. Common cutaneous irritants 7.1.1. Solvents 7.1.1.1. Organic Solvents- Alcohol, turpentine, hair products, ketones, chlorine, esters, paint, acids Diluted Alkalis- Soap and soda Detergents- washing detergents 7.1.2. Microtrauma 7.1.2.1. [mindmeister.com]
(Etiology) Airborne Irritant Contact Dermatitis is a common type of contact dermatitis The condition occurs when the skin is damaged from exposure to irritating dust and chemical vapors, which leads to an allergic reaction Such an exposure is typically [dovemed.com]
Arch Dermatol 99:717–719 PubMed CrossRef Google Scholar Fleming MG, Bergfeld WF (1990) The etiology of irritant contact dermatitis. [link.springer.com]
Skin testing can also be used to screen for an allergic cause of a dermatitis of long duration or unknown etiology, or to identify a suspected allergic component to irritant contact dermatitis. [aafp.org]
Epidemiology
Epidemiology 1.1. Occupational Hazard 1.1.1. repeated handwashing 1.1.2. repeated exposure of skin to irritants 1.2. Prevalence 1.2.1. 55.6% in 2 intensive care units 1.2.2. 69.7% in the most highly exposed workers 1.3. Environmental factors 1.3.1. [mindmeister.com]
Use of skin cleansing agents, especially synthetic detergents with a pH of approximately 5.5 rather than alkaline pH, may help prevent skin disease. [16] Epidemiology United States statistics Irritant contact dermatitis (ICD) is common in occupations [emedicine.medscape.com]
Epidemiology of ACD Affects the old and young, individuals of all races, and both sexes Differences in genders usually based on exposure patterns, such as nickel allergy being seen more frequently in women, presumably due to greater exposure to jewelry [slideshare.net]
“Epidemiology of different types of hand eczema in an industrial city.” Acta Derm Venerol 69: 227-233. Nicholson, P.J., D. Dlewellyn and J.S. English. 2010. [wsiat.on.ca]
Analysis and review of epidemiologic data and human and animal toxicity data indicates that occupational exposure to MDA may result in reversible liver toxicity (hepatotoxicity). [osha.gov]
Pathophysiology
Pathophysiology 2.1. Skin Barrier Disruption 2.1.1. patients with altered barrier function are more prone to developing ICD 2.2. Epidural Cellular Changes 2.3. Cytokin Release hones naïve T-lymphocytes to the skin 2.3.1. [mindmeister.com]
[…] with or without visible skin changes Chronic effects Repeated exposures required Skin dryness Hyperkeratosis Skin itching (less than in ACD) Skin wrinkling Development of allergic contact dermatitis ICD is a spectrum of disease processes with a complex pathophysiology [accessmedicine.mhmedical.com]
The three main pathophysiological changes are skin barrier disruption, epidermal cellular changes, and cytokine release. [3] With sufficient concentration or duration of exposures, a wide range of chemicals can act as cutaneous irritants. [emedicine.medscape.com]
With large or full-thickness burns, hospitalization may be necessary, especially if the patient has circumferential burns of the neck or extremity, a medical condition such as diabetes mellitus, or poor hygiene. 5 ALLERGIC CONTACT DERMATITIS Pathophysiology [aafp.org]
"A Review of the Pathophysiology, Prevention, and Treatment of Irritant Diaper Dermatitis." Current Medical Research and Opinion 20 (May 2004): 645 – 49. Duarte, I., et al. "Contact Dermatitis in Adolescents." [encyclopedia.com]
Prevention
Preventive measures could include the use of PRCBs with less free fiberglass at its edges, vacuuming of the newly cut boards, use of dusting powder, protective devices and emollients, and improved personal hygiene of the workers. [ncbi.nlm.nih.gov]
If you know that you are going to handle fiberglass take preventive measures such as dusting your body with talcum powder. It will block the skin pores and prevent it from penetrating in the skin. [simple-remedies.com]
It is difficult, but not impossible to prevent recurrences. Resume epoxy use only after symptoms disappear, and strictly follow the recommended handling procedures to prevent exposure. [westsystem.com]
It's advisable to take precautions and wear protective clothing, such as long sleeves, gloves and a face mask, when working with fiberglass to prevent skin irritation. [healthfully.com]
The substances causing the allergy must therefore be avoided for life, to prevent the skin from developing contact dermatitis. Prevention is the key. [occderm.asn.au]