The unusual radiologic presentation of an optic chiasm fibrillary astrocytoma extending through and expanding the diaphragma sellae in an 8-year-old male is described. The child presented with decreased vision in the right eye. [ncbi.nlm.nih.gov]

The most common presenting feature (~40% of cases) is seizures. This is particularly the case in adults. Headaches are often also present. [radiopaedia.org]

Each example is presented in a case based format and the wide variety of cases presented covers the entire scope of brain tumors and offers the opportunity to review both the basics for the beginner or relatively inexperienced pathologist and also offers [books.google.com]

• Suicidal Ideation

  Suicide ideation in pediatric and adult survivors of childhood brain tumors. J Neurooncol. 2013 Jul. 113 (3):425-32. [Medline]. Suzuki Y, Takahashi-Fujigasaki J, Akasaki Y, Matsushima S, Mori R et al. [emedicine.medscape.com]

Detection of many of the molecular changes that underlie the development of gliomas and other BT can now be done by immunohistochemistry and is getting into the mainstream of the diagnostic workup of BT. [neuropathology-web.org]

[…] tumors Other studies EEG may be used to evaluate and monitor epileptiform activity ECG and chest radiographs are indicated to evaluate operative risk CSF studies may be used to rule out other diagnoses (eg, metastasis, lymphoma, medulloblastoma) See Workup [emedicine.com]

Treatment[edit] Treatment options include surgery, radiotherapy, radiosurgery, and chemotherapy. [en.wikipedia.org]

Treatment Treatment is controversial. Some tumors may be observed with serial MRI with the assumption that almost all of these tumors will at some point undergo malignant degeneration to a higher grade tumor. [prod.wiki.cns.org]

Surgery is the standard treatment. [braintumor.org]

Our findings emphasize the individuality of PA as a distinct clinicopathologic entity with an exceptional prognosis. [ncbi.nlm.nih.gov]

Prognosis A prognosis is an estimate of the likely progress of a disease after a diagnosis, based on an average patient group. [braintumour.ca]

Very good: Indolent nature -Long term prognosis related to location Favorable, even with large size Total resection is the best option for progression-free survival High-grade astrocytomas Worse prognosis than LGA Higher rate of neuraxis dissemination [pedsoncologyeducation.com]

The prognosis for astrocytoma is pretty different for the different types. [pathologystudent.com]

Etiology • mutations affecting p53 • overexpression of platelet-derived growth factor α (PDGF-A) and its receptor • Disruption of tumor suppressor genes • RB and p16/CDKNaA • tumor suppressor on chromosome 19q most common in the low-grade astrocytomas [slideshare.net]

[…] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]

Etiology Pediatr Blood Cancer 2018 Jan;65(1) Epub 2017 Jul 14 doi: 10.1002/pbc.26717. PMID: 28708330Free PMC Article Broadway SJ, Ogg RJ, Scoggins MA, Sanford R, Patay Z, Boop FA J Neurosurg Pediatr 2011 Jun;7(6):589-95. doi: 10.3171/2011.4.PEDS119. [ncbi.nlm.nih.gov]

MeSH Qualifier] diagnostic imaging [MeSH Qualifier] diet therapy [MeSH Qualifier] drug therapy [MeSH Qualifier] economics [MeSH Qualifier] embryology [MeSH Qualifier] enzymology [MeSH Qualifier] epidemiology [MeSH Qualifier] ethnology [MeSH Qualifier] etiology [chu-rouen.fr]

For the majority of astrocytoma, the etiology is unknown. Children with a familial cancer predisposition have an increased risk for developing both low grade and high grade gliomas. [childrensmn.org]

METHODS: Patients diagnosed with fibrillary, protoplasmic, and gemistocytic astrocytomas were identified through the Surveillance, Epidemiology, and End Results (SEER) database. [ncbi.nlm.nih.gov]

Methods Patients diagnosed with fibrillary, protoplasmic, and gemistocytic astrocytomas were identified through the Surveillance, Epidemiology, and End Results (SEER) database. [thejns.org]

Descriptive epidemiology of cerebral gliomas in France. Cancer. 1997 Mar 15. 79(6):1195-202. [Medline]. Nader Pouratian, Ahok Asthagiri, Jay Jagannathan, Mark E Shaffrey, David Schiff. [emedicine.medscape.com]

English: BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

Definition / general Pilocytic means "hair-like," due to long, bipolar processes Most common CNS neoplasm of childhood Better prognosis than diffuse types, particularly if resectable (such as cerebellar tumors) WHO grade I Epidemiology Most common CNS [pathologyoutlines.com]

It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. [books.google.com]

Pathophysiology Regional effects of astrocytomas include compression, invasion, and destruction of brain parenchyma. [emedicine.com]

Pathophysiology. 2015 Mar. 22 (1):1-13. [Medline]. Lahkola A, Auvinen A, Raitanen J, Schoemaker MJ, Christensen HC, Feychting M, et al. Mobile phone use and risk of glioma in 5 North European countries. Int J Cancer. 2007 Apr 15. 120(8):1769-75. [medscape.com]

Pathophysiology Low-grade astrocytomas are primary tumors (rather than extraaxial or metastatic tumors) of the brain. [emedicine.medscape.com]

But there is no way to prevent them, and there’s nothing you can do to reduce a child’s risk of developing one. [weillcornellbrainandspine.org]

A near-complete resection (less than 10 cc of residual tumor) of low-grade astrocytomas prevents tumor recurrence for longer periods of time. [neurosurgery.ucla.edu]

[…] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention [decs.bvs.br]

There is nothing you could have done, or avoided doing, that would have prevented you from developing a brain tumour. As with most brain tumours, the cause is not known. Research into possible causes is focussing around our genes. [thebraintumourcharity.org]