Other hematological parameters are presented in Table III. [spandidos-publications.com]

Nivestim is a new filgrastim available in three presentations - 48 MU (480 mcg), 30 MU (300 mcg) and the unique 12 MU (120 mcg) low weight presentation. [fiercebiotech.com]

Abstract Bronchiolitis obliterans organizing pneumonia (BOOP) presents with fever, dyspnoea, pleuritic chest pain and hypoxia. [ncbi.nlm.nih.gov]

• Retinal Hemorrhage

  This was complicated by marked hyperleukocytosis and retinal hemorrhages. The patient's symptoms improved gradually following leukopheresis. [ncbi.nlm.nih.gov]

• Ankle Pain

  […] or bruising, purple markings under the skin, red skin decreased urination, dark or bloody urine, swelling of the face or ankles painful, urgent, or frequent urination Some people who used filgrastim injection products to treat severe chronic neutropenia [medlineplus.gov]

Serologic workup was negative for anti-nuclear antibody, antistreptococcal antibodies, hepatitis B and C, ANCA, and antiglomerular basement membrane antibodies. [jasn.asnjournals.org]

• Alanine Aminotransferase Increased

  Observed adverse drug reactions with an incidence of > 5% were back pain (60.6%), bone pain (9.6%), alanine aminotransferase increase (8.7%), aspartate aminotransferase increase (5.8%) and arthralgia (5.8%). [ncbi.nlm.nih.gov]

PURPOSE: Chemotherapy-induced febrile neutropenia (FEN), which causes treatment delays or chemotherapy dose reductions, is a serious side effect of cancer treatment. [ncbi.nlm.nih.gov]

Methods: Descriptive and retrospective study of patients with breast cancer under treatment with FEC 600, had or not received filgrastim, during the year 2002. [dialnet.unirioja.es]

A paper questionnaire concerning home treatment was provided to patients for completion for each treatment cycle with filgrastim. [dovepress.com]

To determine the effect of r-metHu granulocyte colony-stimulating factor (G-CSF) on the proportion of patients with metastatic poor-prognosis malignant germ cell tumors who receive full dose-intensity combination chemotherapy. [jco.ascopubs.org]

[…] with a chemotherapy regimen that carries a >20 per cent risk of febrile neutropenia, elderly and frail patients at increased risk, and patients undergoing high-intensity chemotherapy schedules or where delays in treatment are known adversely to affect prognosis [pharmaceutical-journal.com]

This may have a negative impact on its effectiveness and worsen patient prognosis. [spandidos-publications.com]

Champlin Article Figures/Media 25 References 51 Citing Articles Letters Abstract Background Patients whose leukemia relapses after allogeneic bone marrow transplantation have a poor prognosis; few respond to further chemotherapy, and almost none survive [nejm.org]

International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997; 89 : 2079–2088. 15. Ohara A, Kojima S, Hamajima N, Tsuchida M, Imashuku S, Ohta S et al. [nature.com]

[…] generalized signs and symptoms such as fever, abdominal pain, malaise, back pain, and increased inflammatory markers (e.g., c-reactive protein and white blood cell count) Consider aortitis in patients who develop these signs and symptoms without known etiology [neupogenhcp.com]

Consider aortitis in patients who develop these signs and symptoms without known etiology. Discontinue NIVESTYM TM if aortitis is suspected. [pfizerpro.com]

We thank Robert Ball, MD, MPH, ScM, and Michael Blum, MD, MPH, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, for critical review of this manuscript. [jamanetwork.com]

Author information 1 Department of Medical Oncology, University Hospital Zurich, Zurich, Switzerland. 2 Department of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland. 3 Department of Hematology [ncbi.nlm.nih.gov]

Approved in the EU Oct 13 [4] Category Pharmacology Immunostimulating medicinal product (L03AA02) which regulates the production and release of functional neutrophils from the bone marrow Epidemiology The incidence of drug-induced neutropenia is one case [sps.nhs.uk]

Materials and methods Study design This was a multicenter, non-interventional, real-life, epidemiological study sponsored by Accord Healthcare Polska (Warsaw, Poland), which involved an electronic questionnaire. [spandidos-publications.com]

Sanz Department of Internal Medicine, University of Vienna, Vienna, Austria K Lechner Department of Haematology, University of Ghent, Ghent, Belgium L Noens Clinical Haematology, Royal Melbourne Hospital, Melbourne, Australia J Szer Biostatistics and Epidemiology [nature.com]

This report explores the spectrum of GN with monoclonal IgG deposits and the pathophysiologic role of granulocyte colony-stimulating factor in exacerbation of preexisting GN. [ncbi.nlm.nih.gov]

This thoroughly updated Third Edition covers newly approved drugs, has separate chapters on drugs affecting fungal and viral infections, and includes more pathophysiology information. [books.google.ro]

Pending a better understanding of the pathophysiology of vaso-occlusion, patients with sickle cell disease should receive G-CSF with great caution. Copyright © 2001 The American Society of Hematology References ↵ ↵ Abboud M, Laver J, Blau C-A. [bloodjournal.org]

The pathophysiology of this injury may be attributed to the cytokine nature of G-CSF. [2] As the trough tacrolimus levels are within acceptable limits, with no histopathological features of CNI toxicity, it is unlikely that the ATI is related to the CNI [sjkdt.org]

Recently, Nivestim™, a biosimilar of reference of filgrastim, was approved for prevention of chemotherapy-related febrile neutropenia (FN). [ncbi.nlm.nih.gov]

[…] it as secondary prevention. [spandidos-publications.com]

Nivestim(TM), a New Biosimilar Filgrastim, is Approved in Europe for the Prevention of Febrile Neutropenia Associated With Chemotherapy - Nivestim(TM), Hospira's filgrastim, has received approval from the European Commission (EC) for the prevention of [fiercebiotech.com]

Randomized phase II study of loratadine for the prevention of bone pain caused by pegfilgrastim. Support Care Cancer. 2016 ;24: 3085 - 3093. Google Scholar | Medline | ISI 17. Gavioli, E, Abrams, M. [doi.org]