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First Trimester Pregnancy

Early Placental Phases


Presentation

  • The classification score of early pregnancy loss was equal to (1.66 Maternal age) (0.84 Mean sac diameter) (-0.38 Crown-rump length) 8.69 (if cardiac activity is present) 1.60 (if intrauterine hematomas are present) - 34.77.[ncbi.nlm.nih.gov]
  • Fetal loss rate by chief complaint were as follows: 8 of 46 patients presenting with pain only, 14 of 34 presenting with vaginal bleeding only, and 13 of 37 with both vaginal bleeding and pain.[ncbi.nlm.nih.gov]
  • A 37-year-old gravida 8 para 7 at 9 weeks' gestation presented with left-sided hemiplegia and right gaze preference and underwent successful thrombolysis for a right MCA occlusion.[ncbi.nlm.nih.gov]
  • METHODS: This is a retrospective cohort study of women who presented with bleeding or pain or both during the first trimester of pregnancy. The cohort was divided into subjects diagnosed with IUP vs. (EP SAB).[ncbi.nlm.nih.gov]
  • To improve the reliability of genetic testing, we present methods of appropriate collection and pre-laboratory preparation of chorionic villi from first trimester miscarriage.[ncbi.nlm.nih.gov]
Prolonged Bleeding
  • The most important advantages of misoprostol therapy were avoidance of the risk of uterine perforation (96.4%) and formation of intrauterine adhesions (74.6%), whereas the most significant disadvantages were prolonged bleeding (21.4%), pain (21.4%), and[ncbi.nlm.nih.gov]
Large Breast
  • There had been other signs such as my ravenous appetite and my surprisingly large breasts but that could be chocked up to getting my period.[staceyschaedler.com]

Treatment

  • RESULTS: Medical treatment was successful in 57 and surgical treatment was needed in 7 women. Average pain and bleeding intensity were 5.8 and 5.3, respectively.[ncbi.nlm.nih.gov]
  • Measurements were compared between the group with successful medical treatment and the group in whom treatment failed. RESULTS: In 125 women included in the study, the success rate of misoprostol treatment was 64.8%.[ncbi.nlm.nih.gov]
  • Gestational age did not influence the efficacy of this treatment and the success rate was inversely proportional to parity.[ncbi.nlm.nih.gov]
  • Similar rates of perinatal mortality (stillbirths and neonatal deaths) were observed for each treatment arm (AL 4.4%, SP and/or quinine 3.9%).[ncbi.nlm.nih.gov]
  • […] in a five-year trial, called PROMISE (Progesterone in Miscarriage Treatment).[medicaldaily.com]

Prognosis

  • Correlation of clinical findings, quantitative human chorionic gonadotropin levels and diagnostic ultrasound findings can maximize the efficiency of the work-up, provide a definitive prognosis and identify early ectopic pregnancy.[ncbi.nlm.nih.gov]
  • CONCLUSION(S): Embryonic heart rate, independent of maternal age, is useful to help predict first-trimester pregnancy prognosis after IVF. Infertility patients with a low EHR ([ncbi.nlm.nih.gov]
  • CONCLUSIONS: The finding of a chorionic bump on the first-trimester sonogram is associated with a guarded prognosis for the early pregnancy (live birth rate[ncbi.nlm.nih.gov]

Etiology

  • Sticky platelet syndrome causes arterial thromboses and may be an underappreciated etiology for adverse pregnancy outcomes.[ncbi.nlm.nih.gov]
  • BACKGROUND: The etiology of early pregnancy loss is multifactorial and may include viral pathogens.[ncbi.nlm.nih.gov]
  • Overview of the etiology and evaluation of vaginal bleeding in pregnant women." UpToDate. Updated: Sep 14, 2017. CONTINUE SCROLLING FOR RELATED SLIDESHOW[medicinenet.com]
  • Overview of the etiology and evaluation of vaginal bleeding in pregnant women. UpToDate. Last reviewed: Jan 2019. CONTINUE SCROLLING FOR RELATED SLIDESHOW[medicinenet.com]

Epidemiology

  • KEYWORDS: Congenital anomaly; Depression; Epidemiology; Medication; Registry; SSRI[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • OBJECTIVES: The contribution of local inflammation to the pathophysiology of abnormal choromosomally miscarriages remains unclear The objective of this study was to investigate the inflammatory response at the maternofetal interface of women presenting[ncbi.nlm.nih.gov]
  • BACKGROUND: The contribution of local and systemic inflammation to the pathophysiology of sporadic first trimester miscarriages remains unclear.[ncbi.nlm.nih.gov]

Prevention

  • To this end and to prevent inadvertent harm to early normal pregnancies, the Society of Radiologists in Ultrasound convened a consensus panel of radiologists, obstetricians, and emergency medicine physicians in 2012 with the goal of reviewing current[ncbi.nlm.nih.gov]
  • . • The hormone progesterone also increases as it is needed to relax the muscles in the uterus to prevent early labor.[visembryo.com]
  • Intravenous ampicillin, with or without gentamicin, effectively sterilizes the placenta and prevents maternal and fetal illness and death in cases of listeriosis in early pregnancy.[wwwnc.cdc.gov]
  • (July 31, 2015) Centers for Disease Control and Prevention. Preconception Health and Health Care, Information for Health Professionals. Available online at . Accessed October 2015. (August 25, 2105) Centers for Disease Control and Prevention.[labtestsonline.org]

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