• Miscellaneous : Fatigue, decrease in blood potassium and sugar level, weakness, allergic reactions, Lyell's syndrome. Store it at room temperature (25 C). Advertisement Most Popular On Medindia: [medindia.net]

Adverse Reactions: Cardiac events, chest pain, dyspnea, GI upset, abdominal pain, hepatic dysfunction, elevated creatinine and BUN, blood dyscrasias, ataxia, headache, confusion, fatigue, hypoglycemia, hypokalemia, rash, allergic reactions, others. [empr.com]

After an extensive abdominal operation, a 70-year-old man developed a syndrome of fulminant sepsis due to Candida albicans with the beginnings of renal failure. [ncbi.nlm.nih.gov]

Few human cases of cryptococcosis have been reported over the last 50 years in Turkey. This is the first C. neoformans isolate in Turkey shown to have primary resistance to 5-FC. [ncbi.nlm.nih.gov]

At this time, flucytosine in conjunction with amphotericin B is in theory still a desirable upgrade over fluconazole. [doi.org]

Flucytosine may cause nausea and vomiting. If you take more than one capsule per dose, swallow one capsule at a time over a 15-minute period to help prevent nausea and vomiting. Use this medicine for the full prescribed length of time. [cigna.com]

GIT manifestations: Nausea Vomiting Diarrhea Abdominal cramps and pain 4. Liver enzymes elevation 5. Nephrotoxicity 6. With prolonged use alopecia may occur as resembles anti-neoplastic drugs. [howmed.net]

Administration • Give capsules a few at a time over 15 minutes to minimize nausea and vomiting. • Know that drug is rarely used alone. Expect to give another antifungal or amphotericin B concurrently. [medical-dictionary.thefreedictionary.com]

It is also being tested in combination with the newer anti-fungal agents fluconazole ( Diflucan ) and itraconazole ( Sporanox ): adding flucytosine to these drugs can improve treatment outcomes in HIV-positive patients. 1 2 Side-effects can include nausea [aidsmap.com]

pain, rash, elevated liver enzymes, blood disorders, confusion and headache. [aidsmap.com]

GI toxicity may be severe or rarely fatal and consists of anorexia, abdominal bloating, abdominal pain, diarrhea, dry mouth, duodenal ulcer, GI hemorrhage, nausea, vomiting, and ulcerative colitis. [en.wikipedia.org]

• Gastrointestinal : Nausea, vomiting, abdominal pain, diarrhea, loss of appetite, dry mouth, duodenal ulcer, gastrointestinal bleeding, acute liver injury, liver dysfunction, jaundice, ulcerative colitis, increased level of liver enzymes. • Genitourinary [medindia.net]

Adverse Drug Reactions Although GI manifestations not common, but may lead to: Nausea Vomiting Abdominal pain Skin rashes Alopecia Stevens Johnson syndrome Posaconazole Newer agent discovered having activity against: Candida Aspergillosis Zygomycosis [howmed.net]

Adverse Effects Frequency Not Defined Confusion Headache Hallucinations Dizziness Drowsiness Psychosis Parkinsonism Ataxia Sedation Rash Photosensitivity Pruritus Urticaria Temporary growth failure Hypoglycemia Hypokalemia Nausea Vomiting Diarrhea Abdominal [reference.medscape.com]

[…] for treatment of Candida ophthalmic infections † (keratitis, endophthalmitis). 140 IDSA states that IV amphotericin B with oral flucytosine is the regimen of choice for treatment of Candida endophthalmitis when lesions are advancing or threaten the macula [drugs.com]

Hydrocephalus and profound psychomotor retardation were present one year later. [ncbi.nlm.nih.gov]

• Genitourinary : Creatinine and BUN elevation, crystal in urine and kidney failure. • Blood : Anemia, eosinophilia, decrease in white blood cells and platelets. • Central Nervous System : Incoordination, hearing loss, headache, tingling, Parkinsonism [medindia.net]

A 52-year-old man with a history of HIV (CD4 count 155, and viral load 154 K), who is on antiretroviral treatment presented in the emergency room with acute onset of headache. [ncbi.nlm.nih.gov]

[…] itraconazole ( Sporanox ): adding flucytosine to these drugs can improve treatment outcomes in HIV-positive patients. 1 2 Side-effects can include nausea and vomiting, diarrhoea, abdominal pain, rash, elevated liver enzymes, blood disorders, confusion and headache [aidsmap.com]

• Central Nervous System : Incoordination, hearing loss, headache, tingling, Parkinsonism, peripheral neuropathy, fever, fainting, sleepiness, epilepsy, confusion, hallucinations and psychosis. • Miscellaneous : Fatigue, decrease in blood potassium [medindia.net]

Adverse Effects: Hematologic: leucopenia, thrombocytopenia, bone marrow aplasia Gastric: intestinal perforation, ulcerating enterocolitis Hepatic: elevated liver enzymes, hepatitis, jaundice, azotemia Dermatologic: photosensitivity reaction CNS (rare): headache [antimicrobe.org]

A case of chromoblastomycosis with an unusual clinical manifestation caused by Phialophora verrucosa on an unexposed area: treatment with a combination of amphotericin B and 5-flucytosine. Br J Dermatol. 2005; 152:560-4. 162. [drugs.com]

A case of chromoblastomycosis with an unusual clinical manifestation caused by Phialophora verrucosa on an unexposed area: treatment with a combination of amphotericin B and 5-flucytosine. Br J Dermatol. 2005; 152:560-4. [PubMed 15787829] 162. [web.archive.org]

We used the bacterial pathogen Pseudomonas aeruginosa as a target for the screening of antivirulence activity among marketed drugs. [ncbi.nlm.nih.gov]