We present a case of lateral canthal tendon rupture that presented with an acute right lower eyelid ectropion in a young, renal compromised patient in the setting of recent fluoroquinolone use for pneumonia. [ncbi.nlm.nih.gov]

• Skin Rash

  Quinolone antiobiotic side effects may include: Headaches Skin rash Gastrointestinal problems Allergic reactions 1 Other serious side effects of fluoroquinolone antibiotics may include: Seizures Hallucinations Potential liver damage, kidney damage, or [recallcenter.com]

  The common side effects of the fluoroquinolones are gastrointestinal disturbances, headaches, skin rash and allergic reactions. [livertox.nih.gov]

  rashes and other skin reactions; thyroid problems; autoimmune diseases; blood sugar problems; and emotional problems, sometimes severe, among many other symptoms. [slweb.org]

  problems with memory; problems with speech or speaking; problems with vision or hearing; rash; rash with flat lesions or small raised lesions on the skin; redness; redness of skin; redness, swelling, or soreness of tongue; scarring; seizures; sense [drugs.com]

  If any of the following side effects occur, check with a physician immediately: skin rash or other skin problems such as itching, peeling, hives, or redness fever agitation or confusion hallucinations shakiness or tremors seizures or convulsions tingling [medical-dictionary.thefreedictionary.com]

Yet extensive medical workups do not find any other cause. Worse, there are no known effective treatments. Thus, these people suffer pain and disability for weeks, months, and years." [articles.mercola.com]

• Capnocytophaga

  Methods: Two reference strains ( Capnocytophaga gingivalis ATCC 33624 and Capnocytophaga sputigena ATCC 33612) and four Capnocytophaga spp. isolated from clinical samples were studied. [ncbi.nlm.nih.gov]

• Mycobacterium Chelonae

  While receiving moxifloxacin post LASIK, the patient was diagnosed with moxifloxacin-resistant Mycobacterium chelonae keratitis. [ncbi.nlm.nih.gov]

Treatment failure with multiple doses of ofloxacin was observed in this case of gonorrhea. [ncbi.nlm.nih.gov]

Single-center experience with drug-induced liver injury from India: causes, outcome, prognosis, and predictors of mortality. Am J Gastroenterol 2010; 105: 2396-404. [livertox.nih.gov]

Fluoroquinolone antibiotics (such as olprofloxacin, pefloxacin, ofloxacin, norfloxacin, temafloxacin, etc.) have recently been implicated in the etiology of Achilles tendinitis and subsequent tendon rupture. [ncbi.nlm.nih.gov]

We are more and more being confronted with the advance of multidrug-resistant bacterial etiologies in our patients. [healio.com]

Epidemiology, University of Pennsylvania, Philadelphia, PA. [ncbi.nlm.nih.gov]

This volume covers their mechanisms of action, resistance mechanisms and epidemiology, pharmacokinetics, safety and clinical applications. [lavoisier.fr]

Pathophysiology: Bacterial Resistance Mechanisms Mutations of A Subunits of DNA gyrase Alterations of outer membrane porins Affects organism permeability VIII. [fpnotebook.com]

[…] surveillance data indicating that these medications were associated with subsequent tendonitis and tendon rupture. 4 Several large epidemiological studies have confirmed this association. 5, 6 Secondary cell biology and animal research has elucidated the pathophysiology [bmjopen.bmj.com]

Methods: MICs and mutation prevention concentrations were compared among E. coli strain TOP10 and two corresponding transformants harbouring the OqxAB-encoding plasmids. [ncbi.nlm.nih.gov]