Presentation
We concluded that CSWS is a non specific electrographic pattern observed in some types of epilepsy in childhood that have different clinical presentation. [scielo.br]
Rolandic spikes are also present in children with other generalized epileptiform activity. Abstracts of BRE articles present more details on EEG features and variations for BRE. [pediatrics.emory.edu]
Sudhansu Chokroverty—a world-recognized expert in sleep medicine—presents the third edition of Sleep Disorders Medicine for the latest developments in this rapidly expanding specialty, with coverage of neuroscience and clinical application. [books.google.com]
We do not endorse non-Cleveland Clinic products or services Policy Presentation At age 4, “Jason” began having seizures that consisted of waking up screaming and with right leg stiffening. [consultqd.clevelandclinic.org]
The survey presented a clinical vignette of CSWS. The questions addressed treatment choices for that clinical scenario. Surveys were self-administered and collected using an online survey website (www.surveymonkey.com). [scholars.northwestern.edu]
Jaw & Teeth
- Sialorrhea
The typical seizure characteristics consist of oral-buccal-lingual paresthe-sias, speech arrest, preservation of consciousness, sialorrhea, and tonic or clonic facial movements. [euroformhealthcare.biz]
Psychiatrical
- Fidgeting
Clinically, eye opening and eyelid flutter occur more frequently in absence seizures, whereas fidgeting, smiling, and yawning occurred more frequently with HIHARS. [euroformhealthcare.biz]
Neurologic
- Seizure
According to Lerman, the seizure frequency is low, 13% may have just one seizure, 66% have infrequent seizures, and 21% have frequent seizures. [euroformhealthcare.biz]
Focal seizures can progress to affect both sides of the brain. When this happens, the seizure is called a bilateral seizure, usually tonic-clonic seizures or convulsions. Other seizure types include absence, atypical absence, and atonic seizures. [epilepsy.com]
There are other medical conditions that might cause someone to have a seizure for example, diabetes. The difference between epileptic seizures and other seizures is that epileptic seizures are caused by a disruption in the way the brain is working. [epilepsysociety.org.uk]
Results Clinical characteristics Epileptic seizures occurring in all children mainly included generalized clonic seizure, tonic clonic seizure, myoclonic absence seizure, absence seizure and unilateral limb clonus or mouth and facial seizure. [jitm.hk]
- Dysarthria
Acquired opercular epilepsy with oromotor dysfunction presents with mixed types of seizures and prolonged episodes of dysarthria, a gradual decrease in verbal output, oromotor dysfunction, and deterioration in cognitive function over several weeks to [j-epilepsy.org]
- Apraxia
Apraxia, hemineglect, dyscalculia, intellectual decline, aggressiveness, encopresis, enuresis, emotional lability, psychotic behavior, anxiety and phobias as well as autistic-like behavioral features have also been described. [9], [10], [11], [12] Raha [pediatricneurosciences.com]
- Vertigo
Simple partial seizures are common in nocturnal temporal lobe epilepsy (NTLE); they consist of psychic (e.g., fear, panic, déjà vu), sensory (e.g., gustatory/ olfactory hallucinations, vertigo), or autonomic (e.g., epigastric sensations, nausea, tachycardia [jcsm.aasm.org]
- Tingling
The second patient, a 13-year-old boy, started to have focal seizures at the age of 7 years characterized by a left hand tingling sensation followed by left hand clonus and left arm elevation. [semmelweis.hu]
Treatment
Treatment for continuous spikes and waves during sleep (CSWS): Survey on treatment choices in North America. [scholars.northwestern.edu]
Treatment of epileptic encephalopathies. CNS Drugs 2013; 27: 175-84. 3 Sinclair DB, Snyder TJ. Corticostemids for the treatment of Landau-kleffner Syndrome And continuous spike-wave discharge during sleep. [jitm.hk]
Treatment of CSWS There are no controlled trials for the treatment of CSWS, only large cohort studies. [acnr.co.uk]
But because the child responded well to medical treatment, a wait-and-see approach was justified. [consultqd.clevelandclinic.org]
Valproate, lamotrigine, levetiracetam and sulthiame# may be the most appropriate treatments. The treatment of CSWS, which is responsible for the neuropsychological impairment, is entirely empirical and usually of transient efficacy. [epilepsy.com]
Prognosis
Hence, early diagnosis, effective treatment and termination of continuous spike and slow-wave discharge can ameliorate the prognosis of children [3]. [jitm.hk]
Management options* Seizures are not a major problem as their final prognosis is good. Valproate, lamotrigine, levetiracetam and sulthiame# may be the most appropriate treatments. [epilepsy.com]
Prognosis The prognosis is related to the underlying disorder. The severity of developmental impairment varies with the type of epilepsy. Early infantile epileptic encephalopathy (Ohtahara syndrome) The prognosis is very poor. [emedicine.medscape.com]
The prognosis is worse if the spasms are either symptomatic or cryptogenic. [euroformhealthcare.biz]
Poor prognosis with occ. early death. 3. Neonates. Early myoclonic encephalopathy. Ohtahara syndrome. Infancy. West syndrome. Dravet syndrome. Childhood. Myoclonic astatic epilepsy. Epileptic encephalopathy with CSWS including Landau [slideshare.net]
Etiology
Rett syndrome Metabolic etiologies (e.g. mitochondrial disorders) [epilepsydiagnosis.org]
The developmental prognosis partially depends on the etiology. When classified by etiology, normal development was described in 51% of cryptogenic cases versus only 6% of symptomatic cases. [emedicine.medscape.com]
Significance: ESES/CSWSS syndrome is an epileptic encephalopathy with similar electroclinical findings in children with a >85% spike-wave index and those with a AB - Purpose: To retrospectively analyze the electroclinical features, etiology, treatment [moh-it.pure.elsevier.com]
Etiology Symptomatic, probably symptomatic and idiopathic. [epilepsy.com]
He also had several minor congenital anomalies that suggested a genetic etiology. [articles.complexchild.com]
Epidemiology
GAGNON, Bernadine5 ; MURPHY, Peregrine L2 ; CLARKE, Tara2 ; GREENBERG, David A4 6 ; PAL, Deb K2 4 6 [1] Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States [2] Department of Epidemiology [pascal-francis.inist.fr]
Epidemiology of epilepsy in childhood: a cohort of 440 consecutive patients. Pediatr Neurol. 1998 Jan. 18(1):46-50. [Medline]. Aicardi J, Ohtahara S. Severe neonatal epilepsies with suppression-burst pattern. [emedicine.medscape.com]
Epidemiological study of Landau-Kleffner syndrome (LKS) in Japan. Brain Dev. 2014;36:284–6. 50. Turner SJ, Morgan AT, Perez ER, Scheffer IE. New genes for focal epilepsies with speech and language disorders. Curr Neurosci Rep. 2015;15:35 51. [j-epilepsy.org]
Pathophysiology
In the group of patients with hypermetabolic areas, analyses of pathophysiologic interactions showed disease-related altered functional connectivity between the parietal and frontal cortices. [neurology.org]
The much more common benign epilepsy with centrotemporal spikes is also related to LKS and CSWS by a common pathophysiology. [journals.lww.com]
Some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge. Epilepsia 9, 249-263 (1968). [books.google.com]
The pathophysiological mechanisms of cognitive and behavioral disturbances in children with Landau-Kleffner syndrome or epilepsy with continuous spike-and-waves during slow-wave sleep. Seizure 2006;15(4):249-58. 15. [acnr.co.uk]
Prevention
Sleep EEGs should be performed for timely diagnosis, proper treatment and prevention of permanent cognitive impairment. [pediatricneurosciences.com]
These changes are due to continuous spikes in the frontal region of the brain during sleep that prevent further neurodevelopment. Clinical onset peaks around four to seven years of age. [articles.complexchild.com]
Treatment with clonazepam is effective in preventing most REM parasomnias. Autism and Sleep Sleep-wake problems occur in 40 to 80% of children with autism. [childneurologyfoundation.org]
The EEG could show the pattern of marked sleep activation but the patient need not have the specific epileptic syndromes with either language or global regression. 101 Power Tips For Preventing and Treating Headaches Are you fed up with your frequent [euroformhealthcare.biz]