Symptoma

Focal Epilepsy - Speech Disorder - Mental Retardation

FESD

The survey presented a clinical vignette of CSWS. The questions addressed treatment choices for that clinical scenario. Surveys were self-administered and collected using an online survey website (www.surveymonkey.com). [scholars.northwestern.edu]

We do not endorse non-Cleveland Clinic products or services Policy Presentation At age 4, “Jason” began having seizures that consisted of waking up screaming and with right leg stiffening. [consultqd.clevelandclinic.org]

Rolandic spikes are also present in children with other generalized epileptiform activity. Abstracts of BRE articles present more details on EEG features and variations for BRE. [pediatrics.emory.edu]

Sudhansu Chokroverty—a world-recognized expert in sleep medicine—presents the third edition of Sleep Disorders Medicine for the latest developments in this rapidly expanding specialty, with coverage of neuroscience and clinical application. [books.google.com]

Can present: -Synchronous episodic sl wave act, regardless if clinical sz present. -Bisymmetrical abn mostly biparietal or bitemporal. -Gen abn were seen more often in serious cases than in focal or symmetrical cases. [studystack.com]

  • Cushingoid

    He developed cushingoid features, weight gain, difficulty climbing stairs and insomnia as side effects of therapy. His behavior worsened. After six months of oral steroids, spikes were reduced but still occupied 50 percent of sleep recordings. [consultqd.clevelandclinic.org]

  • Difficulty Climbing Stairs

    He developed cushingoid features, weight gain, difficulty climbing stairs and insomnia as side effects of therapy. His behavior worsened. After six months of oral steroids, spikes were reduced but still occupied 50 percent of sleep recordings. [consultqd.clevelandclinic.org]

  • Nausea

    epigastric sensations, nausea, tachycardia) phenomena and often wake the patient from sleep. 1 Compared to frontal lobe epilepsy, seizures in NTLE are less frequent, not clustered, and tend to lack prominent motor activity unless the seizures become [jcsm.aasm.org]

  • Seizure

    Inclusion criteria were: (1) focal seizures or apparently generalized seizures and focal EEG epileptiform discharges; (2) further occurrence of atypical absences, and myoclonic, atonic, and/or generalized seizures; (3) cognitive impairment and/or behavior [moh-it.pure.elsevier.com]

    EEG of a 16-yr-old child with MR and tonic seizures, showing slow spike wave activity superimposed on a slow BG. 22. EEG of an 11-yr-old pt with LGS showing GPFA. 23. Tonic seizure in a patient with LGS. 24. [slideshare.net]

    […] tonic-clonic seizures, atypical absence, atonic, and other type of seizures. [j-epilepsy.org]

    According to Lerman, the seizure frequency is low, 13% may have just one seizure, 66% have infrequent seizures, and 21% have frequent seizures. [euroformhealthcare.biz]

    Focal seizures can progress to affect both sides of the brain. When this happens, the seizure is called a bilateral seizure, usually tonic-clonic seizures or convulsions. Other seizure types include absence, atypical absence, and atonic seizures. [epilepsy.com]

  • Focal Neurologic Deficit

    She started speaking monosyllables at 18 months and simple sentences (without verbs) at 3 yeas of age and there was no evidence of any focal neurological deficit. Vision and hearing was normal. [indianpediatrics.net]

  • Brain Edema

    Encephalitis / Brain Edema EEG reflects the injury type or presents on opposite hemisphere (coup / contrecoup injury). Trisomy 21 EEG shows sz type, usually TC or IS. [studystack.com]

Treatment for continuous spikes and waves during sleep (CSWS): Survey on treatment choices in North America. Epilepsia, 55 (7), 1099-1108. [scholars.northwestern.edu]

Treatment of CSWS There are no controlled trials for the treatment of CSWS, only large cohort studies. [acnr.co.uk]

But because the child responded well to medical treatment, a wait-and-see approach was justified. [consultqd.clevelandclinic.org]

Significance: ESES/CSWSS syndrome is an epileptic encephalopathy with similar electroclinical findings in children with a 85% spike-wave index and those with a AB - Purpose: To retrospectively analyze the electroclinical features, etiology, treatment [moh-it.pure.elsevier.com]

Treatment of epileptic encephalopathies. CNS Drugs 2013; 27: 175-84. 3 Sinclair DB, Snyder TJ. Corticostemids for the treatment of Landau-kleffner Syndrome And continuous spike-wave discharge during sleep. [jitm.hk]

[…] status epilepticus during sleep or continuous spikes and waves during slow sleep syndrome: A multicenter, long-term follow-up study of 117 patients", abstract "Purpose: To retrospectively analyze the electroclinical features, etiology, treatment and prognosis [moh-it.pure.elsevier.com]

Hence, early diagnosis, effective treatment and termination of continuous spike and slow-wave discharge can ameliorate the prognosis of children [3]. [jitm.hk]

Management options* Seizures are not a major problem as their final prognosis is good. Valproate, lamotrigine, levetiracetam and sulthiame# may be the most appropriate treatments. [epilepsy.com]

 Poor prognosis with occ. early death. 3.  Neonates.  Early myoclonic encephalopathy.  Ohtahara syndrome.  Infancy.  West syndrome.  Dravet syndrome.  Childhood.  Myoclonic astatic epilepsy.  Epileptic encephalopathy with CSWS including Landau [slideshare.net]

The long-term prognosis of this condition is overall poor owing to the persistence of neuropsychological impairment. Therefore, early recognition and effective therapy are necessary to improve long-term prognosis. [link.springer.com]

Significance: ESES/CSWSS syndrome is an epileptic encephalopathy with similar electroclinical findings in children with a 85% spike-wave index and those with a AB - Purpose: To retrospectively analyze the electroclinical features, etiology, treatment [moh-it.pure.elsevier.com]

Rett syndrome Metabolic etiologies (e.g. mitochondrial disorders) [epilepsydiagnosis.org]

The developmental prognosis partially depends on the etiology. When classified by etiology, normal development was described in 51% of cryptogenic cases versus only 6% of symptomatic cases. [emedicine.medscape.com]

Etiology Symptomatic, probably symptomatic and idiopathic. [epilepsy.com]

He also had several minor congenital anomalies that suggested a genetic etiology. [articles.complexchild.com]

Epidemiology of epilepsy in childhood: a cohort of 440 consecutive patients. Pediatr Neurol. 1998 Jan. 18(1):46-50. [Medline]. Aicardi J, Ohtahara S. Severe neonatal epilepsies with suppression-burst pattern. [emedicine.medscape.com]

Epidemiological study of Landau-Kleffner syndrome (LKS) in Japan. Brain Dev. 2014;36:284–6. 50. Turner SJ, Morgan AT, Perez ER, Scheffer IE. New genes for focal epilepsies with speech and language disorders. Curr Neurosci Rep. 2015;15:35 51. [j-epilepsy.org]

In the group of patients with hypermetabolic areas, analyses of pathophysiologic interactions showed disease-related altered functional connectivity between the parietal and frontal cortices. [neurology.org]

The much more common benign epilepsy with centrotemporal spikes is also related to LKS and CSWS by a common pathophysiology. [journals.lww.com]

Some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge. Epilepsia 9, 249-263 (1968). ‏ [books.google.com]

The pathophysiological mechanisms of cognitive and behavioral disturbances in children with Landau-Kleffner syndrome or epilepsy with continuous spike-and-waves during slow-wave sleep. Seizure 2006;15(4):249-58. 15. [acnr.co.uk]

Sleep EEGs should be performed for timely diagnosis, proper treatment and prevention of permanent cognitive impairment. [pediatricneurosciences.com]

These changes are due to continuous spikes in the frontal region of the brain during sleep that prevent further neurodevelopment. Clinical onset peaks around four to seven years of age. [articles.complexchild.com]

Treatment with clonazepam is effective in preventing most REM parasomnias. Autism and Sleep Sleep-wake problems occur in 40 to 80% of children with autism. [childneurologyfoundation.org]

The EEG could show the pattern of marked sleep activation but the patient need not have the specific epileptic syndromes with either language or global regression. 101 Power Tips For Preventing and Treating Headaches Are you fed up with your frequent [euroformhealthcare.biz]