Presentation
The clinical presentations, imaging studies and initial pathology studies can mimic lymphocytic hypophysitis. Here we report additional clinical clues in differentiating these two conditions. [ncbi.nlm.nih.gov]
Entire Body System
- Pain
[…] ictal abdominal pain remains unknown. [ijponline.biomedcentral.com]
Parietal (pah-RIE-eh-tal) lobe- Controls sense of touch, response to pain and temperature, and understanding of language. Occipital (ok-SIP-eh-tal) lobe- Controls vision. Temporal (TEM-por-al) lobe- Controls hearing and memory. [nationwidechildrens.org]
[…] at clothes or lip smacking Eyes moving from side to side Abnormal sensations, such as numbness, tingling, crawling sensation (like ants crawling on the skin) Hallucinations, seeing, smelling, or sometimes hearing things that are not there Abdominal pain [m.ufhealth.org]
Autonomic Seizures Section These seizures are accompanied by autonomic symptoms or signs, such as abdominal discomfort or nausea which may rise into the throat (epigastric rising), stomach pain, the rumbling sounds of gas moving in the intestines (borborygmi [epilepsyontario.org]
- Unconsciousness
Or, in some severe cases, it may cause unconsciousness and convulsions, when your body shakes uncontrollably. Seizures usually come on suddenly. How long and severe they are can vary. A seizure can happen to you just once, or over and over. [webmd.com]
After a brief period of restlessness, there is unconsciousness, generalized muscular activity, excessive salivation, chewing activity, opisthotonos, running movements, and often urination and defecation. [medical-dictionary.thefreedictionary.com]
If a focal seizure spreads from one hemisphere to the other side of the brain, this will give rise to a focal to bilateral seizure. [5] [6] The person will become unconscious and may well have a tonic clonic seizure. [en.wikipedia.org]
- Hyperthermia
The massive muscle activity of the seizures leads to hyperthermia with temperatures as high as 106 degrees Fahrenheit or more, which if sustained, causes irreversible damage to neurons. [dartmouth.edu]
Gastrointestinal
- Nausea
A complex seizure can last for a minute or two, and you may feel a warning sign such as a feeling of uneasiness or nausea before the seizure. You may feel sleepy and confused after the seizure. [healthline.com]
In addition, a variety of migraine-like disturbances such as nausea, headache, dizziness, and visual hallucinations may be associated with pain during the attacks [ 4 ]. [ijponline.biomedcentral.com]
The child may also experience sweating, nausea, or become pale. Complex-partial seizures Complex-partieal seizures commonly occur in the temporal lobe of the brain, which is the area of the brain that controls emotion and memory function. [chp.edu]
Seizures arising from the midline region of the temporal lobe can cause sensations of fear, sensations in the tummy, pallor and nausea. [epilepsyqueensland.com.au]
Psychiatrical
- Anger
One feels emotions, often fear, but sometimes sadness, anger, or joy. There may be a bad smell or a bad taste, a funny feeling in the pit of the stomach or a choking sensation. [epilepsyontario.org]
A person may experience a sudden overwhelming emotion, such as joy, sadness, fear or anger. Others may experience stomach upset, dizziness, a shiver, a tingling or burning sensation, pallor or flushing. [edmontonepilepsy.org]
[…] that starts in one part of your body – usually your hand or face – and then spreads bit by bit to other parts of your body Having repeated movements such as rocking, pedalling or pelvic thrusting Undressing Running or walking Feelings of fear, anxiety, anger [epilepsy.org.uk]
The person may have sudden and unexplainable feelings of joy, anger, sadness or nausea. He or she also may hear, smell, taste, see or feel things that are not real. In a “complex” focal seizure, the person has a loss of consciousness. [mychildwithoutlimits.org]
[…] aware seizures usually start suddenly and are very brief, typically lasting 60 to 120 seconds. [9] Some common symptoms of a focal onset aware seizure, when the person is awake, are: [7] preserved consciousness sudden and inexplicable feelings of fear, anger [en.wikipedia.org]
- Perceptual Distortion
distortions Focal emotional seizures – characterised by feeling emotions such as joy, sadness, anxiety, fear or panic. [epilepsy.org.au]
distortions) Emotional dysfunction (manifesting with emotional changes, such as anxiety, fear, joy, other emotions, or affective signs without subjective emotions) Sensory dysfunction (causing somatosensory, olfactory, visual, auditory, gustatory, or [merckmanuals.com]
- Abnormal Behavior
Seizure: Transient, abnormal electrical discharge from neurons with resultant abnormal behavior or movements. Simple partial seizure: Consciousness preserved during a seizure that involves only a small part of the brain. [childneurologyfoundation.org]
Urogenital
- Uremia
Emotional excess (e.g., fright or anger), fever, or other hypermetabolic states, hypoglycemia, hypocalcemia, hypomagnesemia, hypoxemia, and toxic states (e.g., tetanus, uremia, exogenous, excitatory agents such as amphetamine, aminophyline, lidocaine, [dartmouth.edu]
Neurologic
- Focal Seizure
Focal epileptic seizures can be the first manifestation of a diabetic disorder. Metabolic disturbances, including hyperglycemia, mild hyperosmolality, hyponatremia, and lack of ketoacidosis contribute to the development of partial focal seizures. [ncbi.nlm.nih.gov]
Complex Focal Seizures Complex focal seizures are often preceded by a simple focal seizure (aura). [hopkinsmedicine.org]
Link/Cite Link to this page Cite this page MLA Style "focal seizure." YourDictionary, n.d. Web. 16 January 2019.. APA Style focal seizure. (n.d.). Retrieved January 16th, 2019, from https://www.yourdictionary.com/focal-seizure [yourdictionary.com]
- Paresthesia
Symptoms vary with different lesion locations and may include but not limited to the motor (e.g. rhythmic muscle contractions in one area of the body), somatosensory and sensory alterations manifested by abnormal numbness, paresthesias or other hallucinations [fpnotebook.com]
For example, paresthesias, flashing lights or smells may be perceived if the postcentral gyrus, calcarine cortex or uncus regions are involved in the seizure activity. [dartmouth.edu]
Other symptoms include funny feelings in the skin, known as paresthesias, or absence of sensation, called numbness. Dizziness or a sensation of movement can also occur, as can rapid to and fro movements of the eyes, known as nystagmus. [childneurologyfoundation.org]
Auras may consist of motor activity or sensory, autonomic, or psychic sensations (eg, paresthesias, a rising epigastric sensation, abnormal smells, a sensation of fear, a déjà vu or jamais vu sensation). [merckmanuals.com]
- Mental Deterioration
Any progressive mental deterioration is usually related to the neurologic disorder that caused the seizures rather than to the seizures themselves. Occasionally, seizures are unremitting, as in status epilepticus. [merckmanuals.com]
- Nystagmus
Dizziness or a sensation of movement can also occur, as can rapid to and fro movements of the eyes, known as nystagmus. [childneurologyfoundation.org]
Workup
Routine workup for all patients should include EEG and MRI of the brain; most of the time, the results will be normal. [emedicine.medscape.com]
Ten years after onset of symptoms, he underwent extensive cardiac workup including 24-hour Holter monitor, which resulted in pacemaker placement, which had no effect on his symptoms, and was subsequently deactivated 1 year after placement. [touchneurology.com]
Serum
- Hypoglycemia
If you’re diabetic, hypoglycemia could be a side effect of your diabetes medication, which your doctor might need to adjust or change. If you're not diabetic, hypoglycemia can arise as a result of certain medicines or other conditions. [livestrong.com]
“Unprovoked” seizures are those that are not brought on by a clear cause, such as alcohol withdrawal, heart problems, or hypoglycemia, which is when a person has extremely low blood sugar levels. [nyulangone.org]
They may be genetic and are commonly provoked by severe metabolic upset (electrolyte disturbance, organ failure, hypoglycemia, hypoxia, sedative/alcohol withdrawal, etc). 22-4. Does epilepsy last a lifetime? 22-4. [dartmouth.edu]
The acute causes include hypoglycemia (low blood sugar, hypocalcemia (low blood calcium), meningitis, bacterial toxins (such as shigella), alcohol withdrawal, environmental toxins, electrical shock, and side effects of medication. [childbrain.com]
[…] seizure frequency Expanding intracranial lesions Hemorrhage, hydrocephalus, tumors Hyperpyrexia Drug toxicity (eg, with amphetamines or cocaine), fever, heatstroke Metabolic disturbances Commonly, hypocalcemia (eg, secondary to hypoparathyroidism), hypoglycemia [merckmanuals.com]
Treatment
Treatment For all types of epilepsy, the goal of treatment is to attain seizure freedom. 7 Many options are available to treat partial-onset seizures, either as monotherapy or as an adjunct to another treatment. [uspharmacist.com]
The doctor will watch for side effects to find the best treatment. Surgery may be an option if medication can't control the seizures. [cedars-sinai.edu]
An additional analysis was performed to determine whether a shift from more severe focal seizure subtypes to less severe occurred upon treatment with lacosamide. [ncbi.nlm.nih.gov]
UCB Pharma SA assumes no responsibility of the views expressed and recommended treatments in these volumes. [epilepsy.com]
[…] as needed Counselling about the risks of valproate treatment and the need for effective contraception throughout treatment A review of ongoing treatment by a specialist at least annually A risk acknowledgement form that patients and prescribers will [bestpractice.bmj.com]
Prognosis
Defining the type of epilepsy should now be considered mandatory as it offers the best guide to both management and prognosis. Most epileptic syndromes and diseases are well defined and easy to diagnose. [epilepsy.com]
Abstract OBJECTIVE: To document the effect of unprovoked status epilepticus (SE) on the prognosis for otherwise normal children with focal epilepsy. [pediatrics.aappublications.org]
The prognosis of patients with SPS is similar to that of patients with complex partial seizures. [emedicine.medscape.com]
Prognosis If you have epilepsy and it is not caused by a treatable condition, such as infection, your tendency to have seizures may be life-long and may require long-term treatment with medicines. [drugs.com]
Etiology
If an infectious or a metabolic etiology is suspected, laboratory tests can also be helpful. [amboss.com]
No differences were found between groups regarding sex, age, age at epilepsy onset, duration of epilepsy, frequency of seizures, and etiology. Temporal lobe epilepsies were significantly more activated than frontal lobe epilepsies. [ncbi.nlm.nih.gov]
In addition, SPS are frequently the result of symptomatic lesions, and the underlying etiology may impart additional risk for morbidity or mortality. [emedicine.medscape.com]
Epidemiology
Thurman DJ, Beghi E, Begley CE, et al; ILAE Commission on Epidemiology. Standards for epidemiologic studies and surveillance of epilepsy. Epilepsia. 2011;52(suppl 7):2-26. 3. Taylor RS, Sander JW, Taylor RJ, Baker GA. [uspharmacist.com]
[…] brain can result in SPS, including the following: Developmental abnormalities Vascular lesions Meningitis/focal encephalitis Trauma Tumors Hypoxic insults Postsurgical changes Metabolic and electrolyte shifts Endocrine disorders Medications and toxins Epidemiology [emedicine.medscape.com]
Descriptive epidemiology of epilepsy: Contributions of population-based studies from Rochester, Minnesota. Mayo Clinic Proceedings, 71(6). 576-586. [epilepsyaustralia.net]
The natural history of epilepsy: An epidemiological view. J Neurol Neurosurg Psychiatry 2004;75:1376-81. 3. Cockerell OC, Johnson AL, Sander JW, Shorvon SD. [neurologyindia.com]
Pathophysiology
As the pathophysiological characteristics of this phenomenon remain unclear, this case implies that the posterior parietal cortex is a possible anatomical localization of the central integrator of visual extra-personal orientation. [ncbi.nlm.nih.gov]
In: Lueders HO, Noachtar S (eds) Epilepsy seizures: pathophysiology and clinical semiology. Churchill Livingstone, Philadelphia, pp 237–242 Google Scholar Ebner A, Kerdar MS (2000) Olfactory and gustatory auras. [link.springer.com]
Elucidating this issue is of paramount importance both for understanding the pathophysiology of focal epilepsies and for the development of new pharmacological strategies for drug-resistant forms of these disorders. [sciencedaily.com]
Pathophysiology Any structural lesion of the brain that causes an electrical variation in the surrounding tissue can provide an adequate substrate for epileptogenesis. [emedicine.medscape.com]
Prevention
Prevention If you have epilepsy, the best way to prevent seizures is to take prescribed seizure medicines without missing doses. You should also get enough sleep each night, don't fast and avoid drinking too much alcohol. [drugs.com]
You can’t always prevent seizures, but you can control them with medications. If you’re on a medication for this purpose, take it as instructed by your doctor and don’t miss doses. [healthline.com]
For many people with simple partial seizures, correct treatment can lower or prevent seizures. In some cases, patients may not have any more seizures for the rest of their life. Partial and generalized seizures are often treated differently. [cedars-sinai.edu]