Presentation
To present a new side effect of follitropin beta not shared with highly purified urinary follicle stimulating honnone (FSH). Follitropin beta was administered for preparation of in vitro fertilization-embryo transfer (IVF-ET). [ncbi.nlm.nih.gov]
Do not use solution if particulate matter is present. No other drugs should be added or combined into the Follistim AQ Cartridge. [druglib.com]
Entire Body System
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Candidiasis
[…] effusion / Delayed / Incidence not known new primary malignancy / Delayed / Incidence not known anaphylactoid reactions / Rapid / Incidence not known Moderate fluid retention / Early / 3.6-3.6 migraine / Early / 3.6-3.6 vaginal bleeding / Delayed / 1.0-3.6 candidiasis [pdr.net]
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HELLP Syndrome
syndrome [ Time Frame: measured at or after 20 weeks gestation ] Elevated liver enzyme levels (aspartate aminotransferase 100 U/L), thrombocytopenia (platelet count Gestational diabetes mellitus [ Time Frame: measured at or after 20 weeks gestation ] [clinicaltrials.gov]
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Epilepsy
The subject has a recent history of/or current epilepsy, thrombophilia, diabetes, cardiovascular, gastro-intestinal, hepatic, renal or pulmonary or auto-immune disease requiring regular treatment. [clinicaltrials.gov]
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Collapse
Sonographic evidence of ovulation may include the following: Fluid in the cul-de-sac, Follicle showing marked decrease in size, and Collapsed follicle. [rxlist.com]
Respiratoric
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Rhinitis
Incidence not known ovarian enlargement / Delayed / Incidence not known Mild acne vulgaris / Delayed / 3.6-59.0 headache / Early / 6.7-26.5 nausea / Early / 3.6-13.6 mastalgia / Delayed / 4.2-13.6 abdominal pain / Early / 2.9-12.0 diarrhea / Early / 3.6-7.6 rhinitis [pdr.net]
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Aspiration
Approximately 35 h later ovum retrieval was performed by transvaginal ultrasound-guided follicle aspiration. IVF, embryo transfer and pregnancy follow-up was performed as described elsewhere ( Csemiczky et al., 1995 ). [academic.oup.com]
Gastrointestinal
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Abdominal Cramps
The most frequently reported adverse events were headache, abdominal cramps, vaginal bleeding/spotting and nausea (Table 3 ). One woman taking Bravelle experienced a 'severe' adverse event, compared with three patients in the Follistim group. [rbej.biomedcentral.com]
Musculoskeletal
Urogenital
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Testicular Pain
pain / Early / Incidence not known DRUG INTERACTIONS Black Cohosh, Cimicifuga racemosa: (Major) Due to a lack of data regarding maternal or fetal safety and efficacy, the FDA currently recommends that patients who are pregnant or who are trying to get [pdr.net]
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Vaginal Discharge
discharge / Delayed / 1.0-2.0 leukorrhea / Delayed / 1.0-2.0 pruritus / Rapid / 1.0-2.0 gynecomastia / Delayed / 2.0 breast enlargement / Delayed / 2.0 infection / Delayed / Incidence not known chills / Rapid / Incidence not known testicular pain / Early [pdr.net]
Neurologic
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Aura
Within a few minutes of injection of subcutaneously of follitropin beta, a 27-year-old woman developed a feeling of fever, headache, nausea, vomiting dizziness, and a visual aura consistent with migraine syndrome. [ncbi.nlm.nih.gov]
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Paresthesia
Early / 1.7-2.4 cough / Delayed / 1.7-2.4 malaise / Early / 2.4-2.4 increased urinary frequency / Early / 0-2.4 fatigue / Early / 1.0-2.3 anorexia / Delayed / 1.0-2.0 vomiting / Early / 1.0-2.0 drowsiness / Early / 1.0-2.0 anxiety / Delayed / 1.0-2.0 paresthesias [pdr.net]
Workup
A health practitioner will consider all the information from the workup to establish a diagnosis. See the Infertility article for more on this. [labtestsonline.org]
Although she had regular menstrual cycles, had conceived spontaneously, and had good hormonal and follicular responses to gonadotropic stimulation regimens during the in vitro fertilization workup, she presented with apparent recurrent pregnancy loss [omim.org]
Evaluation of the partner's fertility potential should be included in the workup procedure. [rxlist.com]
Serum
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Liver Function Tests Abnormal
Transient liver function test abnormalities suggestive of hepatic dysfunction, which may be accompanied by morphologic changes on liver biopsy, have been reported in association with Ovarian Hyperstimulation Syndrome (OHSS). [rxlist.com]
Treatment
It could greatly reduce the burden of treatment for poor responders and this deserves further investigation. TRIAL REGISTRATION: ClinicalTrials.gov NCT02046655. The Author 2014. [ncbi.nlm.nih.gov]
Used in the treatment of infertility in women with proven hypopituitarism or who have not responded to clomifene; or in superovulation treatment for assisted conception (such as in vitro fertilization). [uniprot.org]
Prognosis
Abstract In an attempt to examine and compare the effect of the two commercially available recombinant FSH on ovarian stimulation characteristics and IVF cycle outcome, we studied 264 IVF cycles in patients with a favorable prognosis a priori, 198 in [unboundmedicine.com]
[…] [email protected] Abstract In an attempt to examine and compare the effect of the two commercially available recombinant FSH on ovarian stimulation characteristics and IVF cycle outcome, we studied 264 IVF cycles in patients with a favorable prognosis [ncbi.nlm.nih.gov]
Etiology
Management Medical treatment in patients with abnormal levels of FSH depends on the underlying etiology. [emedicine.medscape.com]
Epidemiology
The author reviews in depth the important classification, epidemiology, pathophysiology, complications and prediction, prevention and treatment options for this pathology. [books.google.com]
Pathophysiology
The author reviews in depth the important classification, epidemiology, pathophysiology, complications and prediction, prevention and treatment options for this pathology. [books.google.com]
The follicle stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology. Endocr Rev 1997 ;18: 739 - 773 5. Vannier B, Loosfelt H, Meduri G, Pichon C, Milgrom E. [doi.org]
Prevention
The author reviews in depth the important classification, epidemiology, pathophysiology, complications and prediction, prevention and treatment options for this pathology. [books.google.com]
It helps control the hormone levels that cause an egg to release from the ovaries (prevents premature ovulation). Manufactured by Serono. Administer through injection. Strength 0.25 mg. [ivfmeds.com]
LOSECTIL stands beside acid survivors Vitamin D Levels Linked to Parkinson's Symptoms Keeping the newborn warm at home at winter Its time to prevent cervical cancer Huge Rise in CT, MRI, Ultrasound Scan Use: Study Exercise May Delay Early Aging of People [bddrugs.com]
On the basis of superovulation studies and in vitro experimentation into the roles of steroids in regulating LH, GnRH and GnRH self-priming, the concept that GnSAF has a role in the regulation of LH secretion, the timing of the LH surge and the prevention [citeseerx.ist.psu.edu]
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