Edit concept Question Editor Create issue ticket

Food Allergy

Food Sensitivity


Presentation

  • Case presentations: These are 5 cases of infants and toddlers who presented with various features of gastrointestinal food allergies, the commonest of which is lower gastrointestinal bleed.[ncbi.nlm.nih.gov]
  • The correlation of IgE measurements with presenting symptoms was conducted for each food in 172 children. RESULTS: Of 1,312 food-specific serum IgE measurements, 69.8% were positive.[ncbi.nlm.nih.gov]
  • In the present work, we aimed to uncover the molecular basis of a distinct form of IPEX syndrome presenting at the edge of autoimmunity and severe allergy.[ncbi.nlm.nih.gov]
  • RESULTS: When the presenting signs and symptoms of food allergy are limited to upper airway obstruction, they can be confused with foreign body aspiration.[ncbi.nlm.nih.gov]
  • It is seen in a variety of conditions but has not been reported as a presentation of food allergy. OBJECTIVE: To report AE as an unusual presentation of food allergy in infants.[ncbi.nlm.nih.gov]
Foreign Body Aspiration
  • METHODS: We report an allergic reaction to cashew that was initially misdiagnosed as foreign body aspiration.[ncbi.nlm.nih.gov]
  • First, a two-year-old boy with no history of allergies and suspected foreign body aspiration which was finally diagnosed as an anaphylactic reaction to fish, and secondly a six-year-old girl with multiple food allergies and allergic asthma who during[ncbi.nlm.nih.gov]
Sneezing
  • A wide range of signs and symptoms may develop, from sneezing and hives to swelling of the tongue, lips and throat. Individuals who suspect that they are allergic to rice should consult an allergist/immunologist.[web.archive.org]
  • Symptoms of a food allergy include: • Hives or red, itchy skin • Stuffy or itchy nose, sneezing or itchy, teary eyes • Vomiting, stomach cramps or diarrhea • Angioedema or swelling In some cases, food allergies can cause a severe reaction called anaphylaxis[aaaai.org]
  • Hives (reddish, swollen, itchy areas on the skin) Eczema flare (a persistent dry, itchy rash) Redness of the skin, particularly around the mouth or eyes Itchy mouth or ear canal Nausea or vomiting Diarrhea Stomach pain Nasal congestion or a runny nose Sneezing[foodallergy.org]
  • Symptoms include hand dermatitis, eczema and urticaria; sneezing and other respiratory distress; and lower respiratory problems including coughing, wheezing and shortness of breath.[web.archive.org]
  • Oedema - swelling of the skin, sometimes of the eyes and lips Eczema - a dry and bumpy rash Stomach and Intestinal Reactions: Abdominal pain and bloating Diarrhoea (usually very runny) Vomiting Gas/wind Cramps Nose, Throat and Lung Reactions: Runny Nose Sneezing[foodreactions.org]
Hoarseness
  • Signs of this reaction include: • Hoarseness, throat tightness or a lump in the throat • Wheezing, chest tightness or trouble breathing • Tingling in the hands, feet, lips or scalp If you experience any of these symptoms, call 911 immediately.[aaaai.org]
  • Common symptoms of anaphylaxis: Skin : itching, hives, redness, swelling Mouth : itching, swelling of lips and/or tongue Throat : itching, tightness/closure, hoarseness, difficulty swallowing Chest : shortness of breath, cough, wheeze, chest pain, tightness[allergyasthmanetwork.org]
  • This triggers allergic symptoms that can include: wheezing trouble breathing coughing hoarseness throat tightness belly pain vomiting diarrhea itchy, watery, or swollen eyes hives red spots swelling a drop in blood pressure, causing lightheadedness or[kidshealth.org]
  • Key symptoms of a food allergy include hives, a hoarse voice, and wheezing.[medlineplus.gov]
Nasal Pruritus
  • Upper and lower respiratory tract reactions Upper respiratory reactions typically include nasal congestion, sneezing, nasal pruritus, or rhinorrhea. They are usually observed in conjunction with ocular, skin, or gastrointestinal symptoms.[emedicine.com]
Common Cold
  • . , Probiotics to Prevent or Mitigate the Common Cold , Advances in Nutrition & Food Science , 10.33140/ANFS/02/01/00004 , 2 , 1 , (2017) .[doi.org]
Diarrhea
  • RESULTS: Two infants with AE, diarrhea, and low serum zinc levels were evaluated. Food allergy was found in both infants. The first infant had a serum IgE level of 4642 IU/mL.[ncbi.nlm.nih.gov]
  • Specialty Emergency medicine Symptoms Itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, low blood pressure Food Allergy, Merck Manual "Food Allergies and Intolerances Resource List for Consumers" (PDF).[en.wikipedia.org]
  • Food Protein-Induced Enterocolitis Syndrome (FPIES) , sometimes referred to as a delayed food allergy, is a severe condition causing vomiting and diarrhea.[aaaai.org]
  • Features of FPE are nonbloody diarrhea, malabsorption, protein-losing enteropathy, hypoalbuminemia, and failure to thrive.[ncbi.nlm.nih.gov]
  • This condition can also cause diarrhea and failure to gain weight or height. Once the infant stops eating the food causing the allergy, the symptoms go away.[kidswithfoodallergies.org]
Vomiting
  • Herein, the authors report the case of a five-year-old Caucasian female who was admitted to our Pediatric Acute and Emergency Operative Unit for cyclic vomiting.[ncbi.nlm.nih.gov]
  • Specialty Emergency medicine Symptoms Itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, low blood pressure Food Allergy, Merck Manual "Food Allergies and Intolerances Resource List for Consumers" (PDF).[en.wikipedia.org]
  • Symptoms include vomiting, which starts about 2 hours or later after eating the food causing the condition. This condition can also cause diarrhea and failure to gain weight or height.[kidswithfoodallergies.org]
  • Food Protein-Induced Enterocolitis Syndrome (FPIES) , sometimes referred to as a delayed food allergy, is a severe condition causing vomiting and diarrhea.[aaaai.org]
  • […] a food reaction episode: Skin: Hives - red, itchy bumps on skin Oedema - swelling of the skin, sometimes of the eyes and lips Eczema - a dry and bumpy rash Stomach and Intestinal Reactions: Abdominal pain and bloating Diarrhoea (usually very runny) Vomiting[foodreactions.org]
Food Intolerance
  • Food allergies are more common in children, can be life-threatening and are distinct from food intolerances.[ncbi.nlm.nih.gov]
  • A food intolerance is a food sensitivity that does not involve the individual's immune system.[hc-sc.gc.ca]
  • On the other hand more than 50% of people are food intolerant (a table to help you distinguish between food allergy and food intolerance is provided below)![foodreactions.org]
  • Most are caused by a food intolerance rather than a true food allergy. Unlike a true food allergy, a food intolerance doesn't involve the immune system and may not be as severe.[web.archive.org]
  • What is food intolerance? A food intolerance isn't the same as a food allergy. People with food intolerance may have symptoms such as diarrhoea, bloating and stomach cramps.[nhs.uk]
Nausea
  • These antibodies create the symptoms of a food allergy, such as rash or hives, nausea, stomach pain, diarrhea, itchy skin, shortness of breath, chest pain and anaphylaxis.[ift.org]
  • If you have a reaction to one of these foods you may experience hives, itchiness, swelling of the skin, nausea, vomiting and/or diarrhea. In severe cases, symptoms may also include difficulty breathing and anaphylactic shock.[oakbrookallergists.com]
  • Some allergic reactions to food take hours to develop and cause symptoms such as abdominal pain, nausea, cramping, and diarrhea.[merckmanuals.com]
  • Mild to moderate symptoms may include one or more of the following Hives (reddish, swollen, itchy areas on the skin) Eczema flare (a persistent dry, itchy rash) Redness of the skin, particularly around the mouth or eyes Itchy mouth or ear canal Nausea[foodallergy.org]
  • SYMPTOMS Symptoms of food allergies can include hives, swelling, stomach pain, nausea, vomiting, swollen airways, difficulty breathing, wheezing and a drop in blood pressure.[premierallergyohio.com]
Lactose Intolerance
  • Known as lactose intolerance, it occurs in people who lack an enzyme called lactase, which is needed to digest lactose (a sugar in milk.) Symptoms of lactose intolerance may include abdominal pain and bloating, diarrhoea and flatulence.[hc-sc.gc.ca]
  • In some cases, as with lactose intolerance, the person lacks the chemicals to properly digest certain proteins found in food.[ift.org]
  • Lactose intolerance is an example of a food intolerance that is often confused with a food allergy. Lactose intolerance is when a person has trouble digesting milk sugar, called lactose, leading to stomachaches, bloating, and loose stools.[healthychildren.org]
  • The exceptions are the gluten intolerance syndrome, known as Coeliac disease, and lactose intolerance.[web.archive.org]
  • For example, being allergic to milk is different from not being able to digest it properly because of lactose intolerance.[webmd.com]
Hepatomegaly
  • He had carotenemia with hepatomegaly, which resolved on dietary management. 2015 The Australasian College of Dermatologists. KEYWORDS: allergy; carotenemia; eczema; hepatomegaly[ncbi.nlm.nih.gov]
Urticaria
  • Abstract We report the case of a 28-year-old man who presented palatal itching and genaralized urticaria following ingestion of olive 3 years after being diagnosed with olive pollinosis.[ncbi.nlm.nih.gov]
  • For generalized urticaria and anaphylaxis, intramuscular epinephrine is the first and fundamental treatment line.[ncbi.nlm.nih.gov]
  • We describe the case of a 26-year-old man who developed pruritus, generalized urticaria, and severe angioedema of his lips and tongue with dyspnea within 15 minutes after lychee fruit intake.[ncbi.nlm.nih.gov]
  • Author information 1 Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan. [email protected] Abstract We report a 22-year-old woman with urticaria, dyspnea and bronchial asthma-like attacks after eating curried rice.[ncbi.nlm.nih.gov]
  • Food allergies are classified roughly into 4 clinical types: (1) neonatal and infantile gastrointestinal allergy, (2) infantile atopic dermatitis associated with food allergy, (3) immediate-type food allergy (urticaria, anaphylaxis, etc.), and (4) food[ncbi.nlm.nih.gov]
Flushing
  • Allergic reactions can include: Hives Flushed skin or rash Tingling or itchy sensation in the mouth Face, tongue, or lip swelling Vomiting and/or diarrhea Abdominal cramps Coughing or wheezing Dizziness and/or lightheadedness Swelling of the throat and[fda.gov]
  • The symptoms of food intolerance can include burping, indigestion, gas, loose stools, headaches, nervousness, or a feeling of being "flushed."[kidshealth.org]
  • Symptoms include a sense of impending doom; generalized warmth or flush; tingling of palms, soles of feet or lips; light-headedness; bloating and chest tightness. These can progress into seizures, cardiac arrhythmia, shock and respiratory distress.[web.archive.org]
  • When eaten in large amounts, it can cause flushing, warmth, headache, pressure in your face, chest pain, or feelings of detachment. Yellow dye number 5 can cause hives, although that's rare.[webmd.com]
Chronic Urticaria
  • Pacor ML, Di Lorenzo G, Corrocher R (2001) Efficacy of leukotriene receptor antagonist in chronic urticaria.[dx.doi.org]
  • Food allergy is rarely the cause of chronic urticaria or angioedema.[emedicine.com]
Headache
  • Her vomiting, which was preceded by objective torque vertigo, headache and weakness, had been recurring with constant frequency every two months since she was 3 years old.[ncbi.nlm.nih.gov]
  • While not life-threatening, symptoms can be severe and range from gastrointestinal distress, headache and chronic fatigue.[enjoylifefoods.com]
  • Asthma Bronchitis Otitis Media Sinusitis Dermatologic Acne Canker Sores Eczema Itching Urticaria (Hives) Angioedema Dermatitis Musculoskeletal Joint Pain Low Back Pain Auto – Immune Rheumatoid Arthritis Systemic Lupus Multiple Sclerosis Neurological Headache[foodallergy.com]
  • […] itching, tightness/closure, hoarseness, difficulty swallowing Chest : shortness of breath, cough, wheeze, chest pain, tightness Stomach : vomiting, diarrhea, cramps Heart : weak pulse, dizziness, fainting, cardiac arrest Other : feeling of impending doom, headache[allergyasthmanetwork.org]
  • People infected with the seasonal flu virus feel miserable with fever, chills, muscle aches, coughing, congestion, headache and fatigue for a week or so.[niaid.nih.gov]
Hyperactivity
  • Food allergies are sometimes blamed for such disorders as hyperactivity in children, chronic fatigue, arthritis, and depression, as well as poor athletic performance. However, these associations have not been substantiated.[merckmanuals.com]
  • Additionally, we consider research and education strategies, with the goal to better elucidate pediatric overdiagnosis and mitigate its influence. medical education public health Abbreviation: ADHD — attention-deficit/hyperactivity disorder Overdiagnosis[dx.doi.org]
  • Special considerations in children : An allergic child who itches, sneezes, and wheezes a lot can feel miserable and, therefore, sometimes misbehave or appear hyperactive.[medicinenet.com]
  • Researchers have found that hyperactivity in children may be related to food additives, but only occasionally and only when the child has had a lot of them.[webmd.com]

Workup

  • BAT and CAST are helpful tools in the diagnostic workup for exotic food allergy. Mugwort is suggested as the allergen responsible for,the cross-reactivity presented by this patient, as he had no sensitization to latex or profilin.[ncbi.nlm.nih.gov]
  • This study evaluates if the APT is a valuable tool in the diagnostic workup of children with food allergy-related atopic dermatitis. METHODS: 42 children between 6 months and 12 years of age were selected at the Mofid Children Hospital.[ncbi.nlm.nih.gov]
  • The diagnostic workup supported a primary birch pollen allergy with PR-10 and nsLTPs cross-reactive food allergy. Case 4: a woman with rhino-conjunctivitis, per-operative anaphylaxis due to latex and recent pharyngeal angio-oedema episodes.[ncbi.nlm.nih.gov]
  • Measuring IgE antibodies is useful in the diagnostic workup of allergy and asthma.[dx.doi.org]
  • (See Workup.) [6] Adverse reactions to food that are not immune mediated are not considered to be food allergies. An example is lactose intolerance, which is caused by a deficiency of lactase.[emedicine.com]

Treatment

  • There are multiple different approaches being tried as possible treatments for food allergy.[ncbi.nlm.nih.gov]
  • However, the treatment itself is prolonged and demanding. We examined changes in patient QOL during OIT for food allergy.[ncbi.nlm.nih.gov]
  • The current standard of treatment is strict avoidance of the offending food(s). There are no FDA approved treatments for food allergy.[ncbi.nlm.nih.gov]
  • EAACI will publish the Minimum Standards for the treatment of the allergic child in school to guide policy-makers in the implementation of such a policy change.[web.archive.org]
  • For generalized urticaria and anaphylaxis, intramuscular epinephrine is the first and fundamental treatment line.[ncbi.nlm.nih.gov]

Prognosis

  • Non-IgE-GI-FAs have a favorable prognosis; the majority resolve by 1 year in patients with FPIAP, 1 to 3 years in patients with FPE, and 1 to 5 years in patients with FPIES, with significant differences regarding specific foods.[ncbi.nlm.nih.gov]
  • Component-resolved diagnosis is being rapidly incorporated into clinical use, and sophisticated diagnostic tests that indicate severity and prognosis are on the horizon.[ncbi.nlm.nih.gov]
  • Prognosis was good, with high rates of resolution for the 2 most common food triggers (ie, rice and soy) by 3 years of age. Conclusions.[dx.doi.org]
  • Egg IgE is predictive of allergy outcome and should be used in counseling patients on prognosis.[ncbi.nlm.nih.gov]
  • Saarinen KM, Pelkonen AS, Makela MJ, Savilahti E (2005) Clinical course and prognosis of cow’s milk allergy are dependent on milk-specific IgE status. J Allergy Clin Immunol 116:869–875 CrossRef PubMed Google Scholar 9.[dx.doi.org]

Etiology

  • The etiology of this phenomenon is at present unclear, but has been ascribed by some to tacrolimus treatment. Here we report a case of liver transplant acquired food allergy (LTAFA) in a child who received a split liver graft.[ncbi.nlm.nih.gov]
  • Its etiology and pathogenesis are not fully understood. Identification of novel genetic variants associated with this disease by exome sequencing (exome-seq) may provide new mechanistic insights and new therapeutic targets.[ncbi.nlm.nih.gov]
  • First, it needs to be acknowledged that a more profound understanding of the complex nature of allergic disorders is needed, as it is likely that there are distinct etiologic factors and pathogenetic mechanisms underlying the heterogeneous manifestations[dx.doi.org]
  • Temporal trends in the relative prevalence of dysphagia etiologies from 1999-2009. World J Gastroenterol 2012;18:4335–4341. 8. Shek LP, Lee BW. Food allergy in Asia. Curr Opin Allergy Clin Immunol 2006;6:197–201. 9.[apallergy.org]

Epidemiology

  • Understanding the epidemiology of food allergy is complicated by the difficulty of identifying it on a large scale. The prevalence of food allergy is higher in younger age groups and decreases with age.[ncbi.nlm.nih.gov]
  • Raising clinical awareness amongst health professionals as to the clinical characteristics, epidemiology, investigation, and management of food allergic disorders is key to tackling this growing problem.[ncbi.nlm.nih.gov]
  • Epidemiological data indicated that bites by the tick Amblyomma americanum in the USA, later also by Ixodes species in other continents, resulted in sensitisation to alpha-gal.[ncbi.nlm.nih.gov]
  • Bonn, Germany. 4 MACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France. 5 INSERM U 1168, VIMA: Ageing and chronic diseases Epidemiological[ncbi.nlm.nih.gov]
  • METHODS: To explore the significance of hand eczema as a risk factor for food allergies in adults at the epidemiological level, we performed a cross-sectional web-based questionnaire survey on kitchen workers whose exposures were classed as occupational[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • The development and investigation of biologics for the treatment of IgE-mediated food allergy and eosinophilic esophagitis have provided further insight into the pathophysiology and management of these disorders.[ncbi.nlm.nih.gov]
  • This review will focus on IgE-mediated FAs and how identifying phenotypes may help to better understand the pathophysiological complexity, improve diagnosis and lead to personalized treatment strategies. 2017 John Wiley & Sons Ltd.[ncbi.nlm.nih.gov]
  • There is an urgent need to better define the natural history of FPIES and the pathophysiology of non-IgE-GI-FAs to develop biomarkers and novel therapies.[ncbi.nlm.nih.gov]
  • We are gaining an increasing understanding of the pathophysiology of food allergic disorders and are beginning to comprehend how these result from a failure to establish or maintain normal oral tolerance.[dx.doi.org]
  • SUMMARY: Natural and artificial animal models were used to explore the pathophysiology of asthma, food allergy and anaphylaxis and to improve prophylactic and therapeutic measures.[ncbi.nlm.nih.gov]

Prevention

  • Results from randomised controlled trials on other allergenic solids, vitamin D supplementation, BCG immunisation at birth and eczema prevention are eagerly anticipated in order to inform further preventative strategies.[ncbi.nlm.nih.gov]
  • Only 6.6% stated they follow all current recommendations on food allergy prevention.[ncbi.nlm.nih.gov]
  • Further work is needed to improve knowledge of how to prevent food allergy in the general population.[ncbi.nlm.nih.gov]
  • Various immunotherapy approaches are under investigation to alleviate or prevent food-induced reactions in those who have persistent food allergies.[dx.doi.org]
  • Allergen elimination goals are to prevent acute and chronic food-allergic reactions in the safest and least restrictive environment to supply a balanced diet that promotes health in children and adults. 2015 S. Karger AG, Basel.[ncbi.nlm.nih.gov]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!