Presentation
VL - 130 IS - 7 N2 - The present study documents a characteristic tomographic sellar abnormality in five patients with Forbes-Albright syndrome (ammenorrhea-galactorrhea) and surgically proved pituitary microadenomas. [unboundmedicine.com]
Abstract The present study documents a characteristic tomographic sellar abnormality in five patients with Forbes-Albright syndrome (ammenorrhea-galactorrhea) and surgically proved pituitary microadenomas. [ncbi.nlm.nih.gov]
The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]
Hyperprolactinemia Prolactin secreting pituitary adenomas present four times as frequently in women as in men. It should be noted that both the age of presentation and symptomatology at presentation are markedly different in the sexes. [med.virginia.edu]
A pituitary adenoma may or may not be present. Symptoms are subjective pain in trunk, back, and head; often mental depression. [med.cmu.ac.th]
Entire Body System
- Galactorrhea
TY - JOUR T1 - Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea). [unboundmedicine.com]
[Galactorrheas]. Minucci D, Ambrosini A. Minucci D, et al. Attual Ostet Ginecol. 1968 Jan-Feb;14(1):7-20. Attual Ostet Ginecol. 1968. PMID: 4317962 Italian. No abstract available. [On 5 cases of amenorrhea-galactorrhea syndrome]. [pubmed.ncbi.nlm.nih.gov]
Albright syndrome … Medical dictionary galactorrhea-amenorrhea syndrome — amenorrhea accompanied by galactorrhea, sometimes associated with increased levels of prolactin; several different types are known. [med_en_es.esacademic.com]
Jaw & Teeth
- Oral Pigmentation
Expanding the cutaneous phenotype to include oral pigmentation further characterizes the clinical findings in this mosaic condition, broadens the differential diagnosis of syndromes with oral pigmentation, and in some cases may aid in earlier diagnosis [ncbi.nlm.nih.gov]
Musculoskeletal
- Macrocephaly
E22.1 … Wikipedia List of diseases (F) — A list of diseases in the English wikipedia.DiseasesTOC FaFab* Fabry s diseaseFacFace Faci* Faces syndrome * Facial asymmetry temporal seizures * Facial clefting corpus callosum agenesis * Facial dysmorphism macrocephaly [med_en_es.esacademic.com]
Growth hormone excess can lead to an abnormally large head (macrocephaly) and can potentially cause vision problems. [rarediseases.org]
Breast
- Nipple Discharge
TOC | ENDO *GALACTORRHEA / HYPERPROLACTINEMIA Milky nipple discharge. Galactorrhea technically does not include serous, purulent, or bloody nipple discharge. SX: Milky nipple discharge. [enotes.tripod.com]
Atrial fibrillation paroxysmal Atrial fibrillation permanent Atrial fibrillation persistent Back pain Bilirubin elevation ICD9CM ICD9CM ICD9CM Bleeding early pregnancy Bleeding gastrointestinal Bleeding neonate ICD9CM Bleeding variceal Bradycardia Breast nipple [books.google.com]
Psychiatrical
- Loss of Libido
Some women may experience a loss of libido (interest in sex) and breast pain, especially when prolactin levels begin to rise for the first time, as the hormone promotes tissue changes in the breast. [dict.eudic.net]
They may not recognize a gradual loss of sexual function or libido. [en.wikipedia.org]
Urogenital
- Amenorrhea
TY - JOUR T1 - Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea). [unboundmedicine.com]
Albright syndrome … Medical dictionary galactorrhea-amenorrhea syndrome — amenorrhea accompanied by galactorrhea, sometimes associated with increased levels of prolactin; several different types are known. [med_en_es.esacademic.com]
No abstract available Similar articles Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea). Cohen GH, Dorfman S, Norwood C. Cohen GH, et al. [pubmed.ncbi.nlm.nih.gov]
- Sexual Dysfunction
In contrast, men usually present in the fourth or fifth decades of life and have sexual dysfunction and symptoms related to mass effect attributable to an enlarging sellar mass. [med.virginia.edu]
In men, the most common symptoms of hyperprolactinaemia are decreased libido, sexual dysfunction (in both men and women), erectile dysfunction, infertility, and gynecomastia. [dict.eudic.net]
Intercourse may become difficult or painful because of vaginal dryness. [ medical citation needed ] In men, the most common symptoms of hyperprolactinaemia are decreased libido, sexual dysfunction (in both men and women), erectile dysfunction, infertility [en.wikipedia.org]
dysfunction female1 Sexually transmitted diseases anorectal region26 Sexual precocity41 Shoulder pain Shoulder pain by location Shoulder pain in different age groups8 Small bowel masses38 Small intestine ulceration Smell disturbance Spastic paraplegias [books.google.com]
- Secondary Amenorrhea
[…] when at the age of 18 years have not yet Appeared flows menstrual secondary amenorrhea, a when you have amenorrhea for at least 3 months after a period of regular menstruation. [brainscape.com]
Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica. No known specific anesthetic considerations for this syndrome. Rimoin DL, Schimke RN: Genetic Disorders of the Endocrine Glands. St. Louis, CV Mosby, 1971. [accessanesthesiology.mhmedical.com]
Keywords Psychosomatic Medicine Gonadotropin Secretion Regular Menstrual Cycle Health Foundation Secondary Amenorrhea These keywords were added by machine and not by the authors. [link.springer.com]
- Oligomenorrhea
In one, who presented with hirsutism, oligomenorrhea, obesity, infertility, and enlarged cystic ovaries, the initial diagnosis was polycystic ovarian syndrome. [annals.org]
Workup
Patients deserve a thorough workup. Postgrad Med. 2000;107:165-68, 171. Olive D. Indications for hyperprolactinemia therapy. J Reproduct Med. 1999;44(12 Suppl):1091-94. Luciano AA. Clinical presentation of hyperprolactinemia. [rarediseases.org]
GENERAL PRINCIPLES OF DIAGNOSIS AND TREATMENT Patients presenting with signs and symptoms suggestive of a pituitary adenoma require a comprehensive workup and treatment plan reflecting a strong interdisciplinary effort with endocrinologists, neurosurgeons [med.virginia.edu]
While a majority of patients with endogenous Cushing syndrome have thyrotrophic adenomas (called Cushing Disease - see below), other tumors should also be considered as part of the endocrinologic workup, including adrenal tumors and especially ACTH-secreting [eyewiki.aao.org]
The following laboratory tests are mandatory to confirm this diagnosis: CaP workup and plasma level of PTH. Urine cAMP measurement after PTH challenge. Evaluation of protein Gs activity. [em-consulte.com]
Diagnostic imaging modalities that may be considered include plain radiography, ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and radionuclide bone scanning (as clinically indicated) (see Workup). [emedicine.medscape.com]
X-Ray
- Mediastinal Mass
[…] compartments anatomy and pathology39 Mediastinal masses or widening on chest xray Mediastinitis acute25 Melanonychia Memory loss symptoms elderly patients Meningitis chronic26 Meningitis recurrent25 Mental status changes and coma2 Mesenteric arterial [books.google.com]
- Atelectasis
[…] monoarticular and oligoarticular2 Arthritis pediatric age19 Arthritis polyarticular Ascites Asthenia Asthma childhood4 Ataxia Ataxia acute or recurrent11 Ataxia cerebellar adult onset34a Ataxia cerebellar children34a Ataxia chronic or progressive11 Atelectasis [books.google.com]
Serum
- Hyperprolactinemia
[Hyperprolactinemia as a frequent cause of amenorrhea and galactorrhea]. Rjosk HK, Fahlbusch R, von Werder K. Rjosk HK, et al. Med Klin. 1980 Aug 15;75(17):609-12. Med Klin. 1980. PMID: 6997715 Review. German. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Forbes Albright syndrome Get Update Overview Hyperprolactinemia is characterized by too much prolactin in the blood. [diseaseinfosearch.org]
Nonpuerperal mastitis may induce transient hyperprolactinemia (neurogenic hyperprolactinemia) of about three weeks' duration; conversely, hyperprolactinemia may contribute to nonpuerperal mastitis. [dict.eudic.net]
[…] hormone hypersecretion Non-pregnancy related A-G syndrome Physiological hyperprolactinemia Pituitary stalk compression hyperprolactinemia Pregnancy hyperprolactinemia Pregnancy-related A-G syndrome Prepuberal hyperpituitarism Secondary hyperprolactinemia [icd9data.com]
Hyperprolactinemia and female infertility. J Reprod Med. 1989;34:117-26 [rarediseases.org]
- Androgens Decreased
Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein, Diabetes, 2002, vol. 51 (pg. 2734 - 2741 ) Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study, Diabetes [molehr.oxfordjournals.org]
- Estrogen Decreased
In the luteal-follicle phase transition period the serum levels of progesterone and estrogen decrease and no longer suppress the release of FSH, the cohort of small antral follicles is normally sufficiently in number to produce enough Inhibin B to lower [wikivisually.com]
Treatment
Treatment Basic information Diagnosis Treatment Basic information Diagnosis Treatment Pearls considerations Basic information Diagnosis Treatment Pearls considerations Basic information Diagnosis Treatment Pearls considerations Basic information Diagnosis [books.google.com]
Surgery may be necessary if tumor does not respond to treatment with medications. [diseaseinfosearch.org]
The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]
Prognosis
Prognosis - Forbes Albright syndrome Not supplied. Treatment - Forbes Albright syndrome Two drugs that have been used are the dopamine agonists cabergoline and bromocriptine. Resources - Forbes Albright syndrome Not supplied. [checkorphan.org]
This therapy is given in two forms: Gamma knife or stereotactic radiosurgery Conventional radiation Prolactinoma Prognosis The outcome of patients is based on the accomplishment of medical treatment or surgery. [hxbenefit.com]
Thus, the prognosis varies according to the manifestations of MAS. With precocious puberty, the prognosis depends on the duration of premature estrogen exposure. [emedicine.medscape.com]
Parents should talk to their child’s physician and medical team about their specific case, associated symptoms and overall prognosis. The parts of the body most commonly affected by MAS are the bone, skin and endocrine system. [rarediseases.org]
Etiology
Article in It | MEDLINE | ID: mdl-5535854 Subject(s) Adenoma, Chromophobe/complications Amenorrhea/diagnosis Follicle Stimulating Hormone/urine Lactation Disorders/diagnosis Pituitary Neoplasms/complications Adult Amenorrhea/etiology Cerebral Angiography [carphaevidenceportal.bvsalud.org]
At the beginning of this century cases were described with symptoms of hypofunction identical with those of postoperative hypoparathyroidism but with absence of the etiologic factor, the operation. [jamanetwork.com]
Osteomalacia and late ricketts, the various etiologies met in the U.S with emphasis on that resulting from a specific form of renal acidosis, the therapeutical indications for each etiological subgroup, and the relationship between osteomalacia and Milkman's [sites.google.com]
; Albright hereditary osteodystrophy is a hereditary metabolic disorder of dominant autosomal etiology that is commonly characterized by short stature, round face, small metacarpus and metatarsus ... [wjiivujb.gq]
Etiology of fibrous dysplasia and McCune-Albright syndrome. Int J Oral Maxillofac Surg. 1999 Oct. 28(5):366-71. [Medline]. Diaz A, Danon M, Crawford J. McCune-Albright syndrome and disorders due to activating mutations of GNAS1. [emedicine.medscape.com]
Epidemiology
The risk of diabetes or metabolic syndrome in KS Epidemiological studies Epidemiological study concerning mortality in KS has been performed in Great Britain ( Swerdlow et al ., 2005 ) and in Denmark ( Bojesen et al ., 2004 ) including more than 3500 [molehr.oxfordjournals.org]
Metyrapone may also be used for treatment. [12] Epidemiology [ edit ] McCune–Albright syndrome is estimated to occur at a frequency between 1 person in 100,000 to 1 person in 1,000,000 individuals worldwide. [15] Notable cases [ edit ] Mauricio Saravia [en.wikipedia.org]
Epidemiology United States and international statistics The exact incidence of MAS in the United States and internationally is unknown, but its prevalence is probably between 1 case in 100,000 population and 1 case in 1 million population, rendering it [emedicine.medscape.com]
[…] less commonly patients may also have Ocular motility deficits and/or Diplopia, certain forms of Nystagmus, signs and symptoms of Increased intracranial pressure due to mass effect, Optic atrophy, or sequelae of Pituitary apoplexy. [3] [4] [5] General Epidemiology [eyewiki.aao.org]
Pathophysiology
Pathophysiology, clinical significance, therapy]. Von Werder K, Fahlbusch R, Rjosk HK. Von Werder K, et al. Internist (Berl). 1977 Oct;18(10):520-8. Internist (Berl). 1977. PMID: 338540 Review. German. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Physiology, pathophysiology and clinical management. Philadelphia, Saunders, 1978, pp. 297-372. What is an eponym? An eponym is a word derived from the name of a person, whether real or fictional. [whonamedit.com]
Hyperprolactinemia: pathophysiology and management. Treat Endocrinol. 2003;2:23-32. Lamberts SW, Quik RF. A comparison of the efficacy and safety of pergolide and bromocriptine in the treatment of hyperprolactinemia. [rarediseases.org]
The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. J Clin Endocrinol Metab. 2008 Jun. 93(6):2383-9. [Medline]. [Full Text]. Lietman SA, Ding C, Levine MA. [emedicine.medscape.com]
Prevention
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]
Drugs such as letrozole and anastrozole can sindrome forbes albright used to prevent short stature in both males and females. [todaypdf.pw]
And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]
Prevention - Forbes Albright syndrome Not supplied. [checkorphan.org]
[…] a woman from releasing an egg, setting the stage for the first birth control pills, • show that progesterone can prevent uterine cancer in women who lack that hormone, • demonstrate the cause of overactive adrenal glands (Cushing's syndrome), • warn [drmirkin.com]