Presentation
The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]
Hyperprolactinemia Prolactin secreting pituitary adenomas present four times as frequently in women as in men. It should be noted that both the age of presentation and symptomatology at presentation are markedly different in the sexes. [med.virginia.edu]
Abstract The present study documents a characteristic tomographic sellar abnormality in five patients with Forbes-Albright syndrome (ammenorrhea-galactorrhea) and surgically proved pituitary microadenomas. [ncbi.nlm.nih.gov]
On Clinical examination-general survey and systemic examination, there was no significant abnormality noted except for milk secretion present in both breasts. [medcraveonline.com]
VL - 130 IS - 7 N2 - The present study documents a characteristic tomographic sellar abnormality in five patients with Forbes-Albright syndrome (ammenorrhea-galactorrhea) and surgically proved pituitary microadenomas. [unboundmedicine.com]
Entire Body System
- Galactorrhea
Polski Tygodnik Lekarski 26(5): 184-186, 1971 The effect of levodopa on galactorrhea in the Forbes-Albright syndrome. Canadian Medical Association Journal 107(6): 534 Passim, 1972 The effect of l dopa on galactorrhea in the forbes albright syndrome. [eurekamag.com]
No abstract available Similar articles Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea). Cohen GH, Dorfman S, Norwood C. Cohen GH, et al. [pubmed.ncbi.nlm.nih.gov]
Forbes-Albright syndrome --- an endocrine disease characterized by amenorrhea, prolactinemia, and galactorrhea, caused by an adenoma of the anterior pituitary. [w1.med.cmu.ac.th]
[…] syndrome Galactorrhea-Amenorrhea without Pregnancy nonpuerperal Amenorrhea-galactorrhea Nonpuerperal galactorrhea Nonpuerperal Galactorrhea-Amenorrhea フォーブス・アルブライト症候群 フォーブス・オルブライト症候群 フォルベス・アルブライト症候群 乳汁漏出無月経症候群 非産褥性乳汁漏出症 無月経・乳汁漏出症候群 解説語: 関連語: WebLSDに未収録 [lsd-project.org]
TY - JOUR T1 - Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea). [unboundmedicine.com]
- Short Stature
Drugs such as letrozole and anastrozole can sindrome forbes albright used to prevent short stature in both males and females. [todaypdf.pw]
Pachyderma, brachydactyly (especially of the 4th and 5th fingers, so-called knuckle-knuckle-dimple sign), short stature, obesity, oligophrenia, calcification of the basal ganglia and multiple skeletal anomalies. [altmeyers.org]
stature, short fingers, round face, and mental retardation) • McCune-Albright syndrome (a genetic disease characterized by deformed, easily broken bones, premature sexual maturity, enlargement of the adrenal glands and the overproduction of cortisol) [drmirkin.com]
[…] in childhood, however premature bone maturation may lead to early growth plate fusion and short stature in adulthood. [en.wikipedia.org]
; Albright hereditary osteodystrophy is a hereditary metabolic disorder of dominant autosomal etiology that is commonly characterized by short stature, round face, small metacarpus and metatarsus ... [wjiivujb.gq]
- Fatigue
Myalgic encephalomyelitis/chronic fatigue syndrome: clinical working case definition, diagnostic and treatment protocols. Journal of chronic fatigue syndrome. 2003 Jan 1;11(1):7-115. [canada.ca]
[…] poliomyelitis, about 25 40 of cases lead to post - polio syndrome Symptoms include muscle pain, further weakening of muscles and paralysis but withdrew before the match began after being diagnosed with Sjogren s syndrome an autoimmune disease which causes fatigue [amp.en.google-info.in]
Systemic symptoms include generalized weakness, fatigue, myopathy, and metabolic effects including hypertension, glucose intolerance, osteoporosis, menstrual abnormalities, and immunosuppression. [med.virginia.edu]
Side effects Nasal congestion, nausea, vomiting, constipation, dyspepsia, orthostatic hypotension, fatigue, sleepiness, cold vasoconstriction, impaired bladder function vasospasms fingers in patients with Parkinson's with high doses - agitation, mental [drdoping.com]
Cushing syndrome causes weight gain in the face and upper body, slowed growth in children, fragile skin, fatigue, and other health problems. In people with McCune-Albright syndrome, Cushing syndrome occurs only before age 2. [ghr.nlm.nih.gov]
- Swelling
[…] parenchymal disease chronic16a Renal vein thrombosis causes Retinopathy hypertensive Rhinitis Rib defects on xray16a Rib notching on xray16a Right axis deviation22 Salivary gland enlargement Salivary gland secretion decreased Scrotal pain28 Scrotal swelling [books.google.com]
Polyostotic fibrous dysplasia often presents as a painless swellings on the ribs. Fibrous dysplasia affecting the spine can cause abnormal curvature of the spine (scoliosis), which is often progressive. [rarediseases.org]
- Hodgkin Lymphoma
Anne Pappenheimer Forbes died of Hodgkin’s lymphoma in 1992. She was 80 years old. The author acknowledges the use of Harvard Medicine magazine’s Autumn 2015 article, “A Woman’s Work.” [columbiamedicinemagazine.org]
She was a caretaker for her husband while he suffered from dementia, and she helped to care for her grandchildren while their mothers worked.[1] She died in 1992, before her husband, of Hodgkin lymphoma.[6] Forbes-Albright syndrome was the name given [en.wikipedia.org]
Gastrointestinal
- Nausea
Overdose and treatment Overdose may cause nausea, vomiting, and severe hypotension. Treatment includes emptying the stomach by aspiration and lavage, and administering I.V. fluids to treat hypotension. [glowm.com]
If medication doesn't shrink the tumor, or you can't take it because of side effects (like nausea or dizziness ), your doctor may recommend surgery to take the tumor out through your nasal cavity. [webmd.com]
Side effects Nasal congestion, nausea, vomiting, constipation, dyspepsia, orthostatic hypotension, fatigue, sleepiness, cold vasoconstriction, impaired bladder function vasospasms fingers in patients with Parkinson's with high doses - agitation, mental [drdoping.com]
[…] tranquillizers ( phenothiazines ), trifluoperazine (Stelazine), and haloperidol (Haldol); antipsychotic medications, such as risperidone and quetiapine ; metoclopramide (Reglan), domperidone, cisapride used to treat gastro-oesophageal reflux ; medication-induced nausea [dict.eudic.net]
Prolactinoma symptoms in males These include: Gynecomastia Impotency Vision problems (such as Visual field loss, Double vision and Drooping eyelids) Nasal Drainage Inability to smell things Low sexual desire Headache Infertility Lethargy Vomiting and nausea [hxbenefit.com]
- Vomiting
Overdose and treatment Overdose may cause nausea, vomiting, and severe hypotension. Treatment includes emptying the stomach by aspiration and lavage, and administering I.V. fluids to treat hypotension. [glowm.com]
Side effects Nasal congestion, nausea, vomiting, constipation, dyspepsia, orthostatic hypotension, fatigue, sleepiness, cold vasoconstriction, impaired bladder function vasospasms fingers in patients with Parkinson's with high doses - agitation, mental [drdoping.com]
Prolactinoma symptoms in males These include: Gynecomastia Impotency Vision problems (such as Visual field loss, Double vision and Drooping eyelids) Nasal Drainage Inability to smell things Low sexual desire Headache Infertility Lethargy Vomiting and [hxbenefit.com]
There was no history of convulsions or vomiting. Regarding her menstrual history, she complained of irregular menstrual cycles–amenorrhea for last 4 months. [medcraveonline.com]
Jaw & Teeth
- Oral Pigmentation
Expanding the cutaneous phenotype to include oral pigmentation further characterizes the clinical findings in this mosaic condition, broadens the differential diagnosis of syndromes with oral pigmentation, and in some cases may aid in earlier diagnosis [ncbi.nlm.nih.gov]
Breast
- Nipple Discharge
TOC | ENDO *GALACTORRHEA / HYPERPROLACTINEMIA Milky nipple discharge. Galactorrhea technically does not include serous, purulent, or bloody nipple discharge. SX: Milky nipple discharge. [enotes.tripod.com]
Atrial fibrillation paroxysmal Atrial fibrillation permanent Atrial fibrillation persistent Back pain Bilirubin elevation ICD9CM ICD9CM ICD9CM Bleeding early pregnancy Bleeding gastrointestinal Bleeding neonate ICD9CM Bleeding variceal Bradycardia Breast nipple [books.google.com]
Psychiatrical
- Loss of Libido
Some women may experience a loss of libido (interest in sex) and breast pain, especially when prolactin levels begin to rise for the first time, as the hormone promotes tissue changes in the breast. [dict.eudic.net]
They may not recognize a gradual loss of sexual function or libido. [en.wikipedia.org]
Neurologic
- Stroke
[…] pediatric age23 Stroke young adult causes1 St segment elevations nonischemic Sudden death pediatric age4 Sudden death young athlete Swollen limb Tall stature27 Tardive dyskinesia13 Taste and smell loss1 Telangiectasia Tendinopathy26 Testicular failure10 [books.google.com]
• Structural problems: Strokes and fluid buildup in the brain may increase risk of Parkinson's disease. • Low levels of folic acid: A few studies suggest that folic acid deficiency may cause some cases of Parkinson's disease. • Head trauma: Any damage [drmirkin.com]
- Structural problems: Strokes and fluid buildup in the brain may increase risk of Parkinson's disease. - Low levels of folic acid: A few studies suggest that folic acid deficiency may cause some cases of Parkinson's disease. - Head trauma: Any damage [targethealth.com]
Patients can have decreased consciousness or strokes from extravasation of blood into the subarachnoid space. The life-threatening emergency associated with pituitary apoplexy is adrenal crisis, as well as other acute endocrine abnormalities. [eyewiki.aao.org]
Urogenital
- Amenorrhea
Annales d'Endocrinologie 19(4): 719-724, 1958 Amenorrhea-Galactorrhea Syndrome (Chiari-Frommel Syndrome and the Forbes-Albright or de Argonz-del Castillo Syndrome). [eurekamag.com]
No abstract available Similar articles Tomographic diagnosis of pituitary microadenomas in Forbes-Albright syndrome (amenorrhea-galactorrhea). Cohen GH, Dorfman S, Norwood C. Cohen GH, et al. [pubmed.ncbi.nlm.nih.gov]
Forbes-Albright syndrome --- an endocrine disease characterized by amenorrhea, prolactinemia, and galactorrhea, caused by an adenoma of the anterior pituitary. [w1.med.cmu.ac.th]
シソーラス検索結果 同義語(異表記): Ahumada-Del Castillo syndrome Amenorrhea-Galactorrhea Syndrome Amenorrhea-Galactorrhea-FSH Decrease Syndrome Argonz-Ahumada-Del Castillo syndrome Argonz-Del Castillo Syndrome Forbes-Albright syndrome Forbes-Albright症候群 Galactorrhea-amenorrhea [lsd-project.org]
Albright syndrome … Medical dictionary galactorrhea-amenorrhea syndrome — amenorrhea accompanied by galactorrhea, sometimes associated with increased levels of prolactin; several different types are known. [translate.academic.ru]
- Secondary Amenorrhea
[…] when at the age of 18 years have not yet Appeared flows menstrual secondary amenorrhea, a when you have amenorrhea for at least 3 months after a period of regular menstruation. [brainscape.com]
Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica. No known specific anesthetic considerations for this syndrome. Rimoin DL, Schimke RN: Genetic Disorders of the Endocrine Glands. St. Louis, CV Mosby, 1971. [accessanesthesiology.mhmedical.com]
[Prolactin-secreting hypophyseal adenomas as a cause of secondary amenorrhea and galactorrhea]. Bogdanova EA. Bogdanova EA. Akush Ginekol (Mosk). 1979 Oct;(10):5-7. Akush Ginekol (Mosk). 1979. PMID: 389081 Review. Russian. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Clinical aspects Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica. Anesthetic considerations No known specific anesthetic considerations for this syndrome. [accesspediatrics.mhmedical.com]
Keywords Psychosomatic Medicine Gonadotropin Secretion Regular Menstrual Cycle Health Foundation Secondary Amenorrhea These keywords were added by machine and not by the authors. [link.springer.com]
- Sexual Dysfunction
In contrast, men usually present in the fourth or fifth decades of life and have sexual dysfunction and symptoms related to mass effect attributable to an enlarging sellar mass. [med.virginia.edu]
In men, the most common symptoms of hyperprolactinaemia are decreased libido, sexual dysfunction (in both men and women), erectile dysfunction, infertility, and gynecomastia. [dict.eudic.net]
Intercourse may become difficult or painful because of vaginal dryness. [ medical citation needed ] In men, the most common symptoms of hyperprolactinaemia are decreased libido, sexual dysfunction (in both men and women), erectile dysfunction, infertility [en.wikipedia.org]
dysfunction female1 Sexually transmitted diseases anorectal region26 Sexual precocity41 Shoulder pain Shoulder pain by location Shoulder pain in different age groups8 Small bowel masses38 Small intestine ulceration Smell disturbance Spastic paraplegias [books.google.com]
- Oligomenorrhea
In one, who presented with hirsutism, oligomenorrhea, obesity, infertility, and enlarged cystic ovaries, the initial diagnosis was polycystic ovarian syndrome. [annals.org]
Workup
Patients deserve a thorough workup. Postgrad Med. 2000;107:165-68, 171. Olive D. Indications for hyperprolactinemia therapy. J Reproduct Med. 1999;44(12 Suppl):1091-94. Luciano AA. Clinical presentation of hyperprolactinemia. [rarediseases.org]
GENERAL PRINCIPLES OF DIAGNOSIS AND TREATMENT Patients presenting with signs and symptoms suggestive of a pituitary adenoma require a comprehensive workup and treatment plan reflecting a strong interdisciplinary effort with endocrinologists, neurosurgeons [med.virginia.edu]
While a majority of patients with endogenous Cushing syndrome have thyrotrophic adenomas (called Cushing Disease - see below), other tumors should also be considered as part of the endocrinologic workup, including adrenal tumors and especially ACTH-secreting [eyewiki.aao.org]
The following laboratory tests are mandatory to confirm this diagnosis: CaP workup and plasma level of PTH. Urine cAMP measurement after PTH challenge. Evaluation of protein Gs activity. [em-consulte.com]
Diagnostic imaging modalities that may be considered include plain radiography, ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and radionuclide bone scanning (as clinically indicated) (see Workup). [emedicine.medscape.com]
Serum
- Hyperprolactinemia
[Hyperprolactinemia as a frequent cause of amenorrhea and galactorrhea]. Rjosk HK, Fahlbusch R, von Werder K. Rjosk HK, et al. Med Klin. 1980 Aug 15;75(17):609-12. Med Klin. 1980. PMID: 6997715 Review. German. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Thus with Cabergoline, the symptoms of hyperprolactinemia resolved and the tumour size markedly regressed Figures 1–4. Figure 1 MRI brain of the patient. [medcraveonline.com]
US National Guidelines Clearinghouse NICE Guidance FDA on Hyperprolactinemia CDC on Hyperprolactinemia Hyperprolactinemia in the news Blogs on Hyperprolactinemia Directions to Hospitals Treating Hyperprolactinemia Risk calculators and risk factors for [wikidoc.org]
[…] hormone hypersecretion Non-pregnancy related A-G syndrome Physiological hyperprolactinemia Pituitary stalk compression hyperprolactinemia Pregnancy hyperprolactinemia Pregnancy-related A-G syndrome Prepuberal hyperpituitarism Secondary hyperprolactinemia [icd9data.com]
- Androgens Decreased
Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein, Diabetes, 2002, vol. 51 (pg. 2734 - 2741 ) Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study, Diabetes [molehr.oxfordjournals.org]
- Estrogen Decreased
In the luteal-follicle phase transition period the serum levels of progesterone and estrogen decrease and no longer suppress the release of FSH, the cohort of small antral follicles is normally sufficiently in number to produce enough Inhibin B to lower [wikivisually.com]
Treatment
Treatment Basic information Diagnosis Treatment Basic information Diagnosis Treatment Pearls considerations Basic information Diagnosis Treatment Pearls considerations Basic information Diagnosis Treatment Pearls considerations Basic information Diagnosis [books.google.com]
Surgery may be necessary if tumor does not respond to treatment with medications. [diseaseinfosearch.org]
The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]
Diagnosis and treatment of prolactinomas. Molitch ME. Molitch ME. Adv Intern Med. 1999;44:117-53. Adv Intern Med. 1999. PMID: 9929707 Review. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Prognosis
Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Hyperprolactinemia from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, Complications and Prognosis [wikidoc.org]
Prognosis - Forbes Albright syndrome Not supplied. Treatment - Forbes Albright syndrome Two drugs that have been used are the dopamine agonists cabergoline and bromocriptine. Resources - Forbes Albright syndrome Not supplied. [checkorphan.org]
Outlook / Prognosis What can I expect if I have a child with McCune-Albright syndrome? Prognosis is dependent on the severity of the diagnosis in your child. Most people diagnosed with McCune-Albright syndrome have a normal life expectancy. [my.clevelandclinic.org]
This therapy is given in two forms: Gamma knife or stereotactic radiosurgery Conventional radiation Prolactinoma Prognosis The outcome of patients is based on the accomplishment of medical treatment or surgery. [hxbenefit.com]
Thus, the prognosis varies according to the manifestations of MAS. With precocious puberty, the prognosis depends on the duration of premature estrogen exposure. [emedicine.medscape.com]
Etiology
Article in It | MEDLINE | ID: mdl-5535854 Subject(s) Adenoma, Chromophobe/complications Amenorrhea/diagnosis Follicle Stimulating Hormone/urine Lactation Disorders/diagnosis Pituitary Neoplasms/complications Adult Amenorrhea/etiology Cerebral Angiography [carphaevidenceportal.bvsalud.org]
PMID: 2608212 [Prolactinoma: etiology, pathogenesis, clinical course and treatment]. Dedov II, Mel'nichenko GA, Langner TK, Kornienko VN. Dedov II, et al. Akush Ginekol (Mosk). 1985 Feb;(2):3-7. Akush Ginekol (Mosk). 1985. PMID: 3158226 Review. [pubmed.ncbi.nlm.nih.gov]
At the beginning of this century cases were described with symptoms of hypofunction identical with those of postoperative hypoparathyroidism but with absence of the etiologic factor, the operation. [jamanetwork.com]
Osteomalacia and late ricketts, the various etiologies met in the U.S with emphasis on that resulting from a specific form of renal acidosis, the therapeutical indications for each etiological subgroup, and the relationship between osteomalacia and Milkman's [sites.google.com]
; Albright hereditary osteodystrophy is a hereditary metabolic disorder of dominant autosomal etiology that is commonly characterized by short stature, round face, small metacarpus and metatarsus ... [wjiivujb.gq]
Epidemiology
Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hyperprolactinemia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Hyperprolactinemia from other Diseases Epidemiology [wikidoc.org]
The risk of diabetes or metabolic syndrome in KS Epidemiological studies Epidemiological study concerning mortality in KS has been performed in Great Britain ( Swerdlow et al ., 2005 ) and in Denmark ( Bojesen et al ., 2004 ) including more than 3500 [molehr.oxfordjournals.org]
Epidemiology United States and international statistics The exact incidence of MAS in the United States and internationally is unknown, but its prevalence is probably between 1 case in 100,000 population and 1 case in 1 million population, rendering it [emedicine.medscape.com]
Metyrapone may also be used for treatment.[16] Epidemiology[edit] McCune–Albright syndrome is estimated to occur at a frequency between 1 person in 100,000 to 1 person in 1,000,000 individuals worldwide.[24] See also[edit] List of cutaneous conditions [en.wikipedia.org]
Pathophysiology
Pathophysiology, clinical significance, therapy]. Von Werder K, Fahlbusch R, Rjosk HK. Von Werder K, et al. Internist (Berl). 1977 Oct;18(10):520-8. Internist (Berl). 1977. PMID: 338540 Review. German. No abstract available. [pubmed.ncbi.nlm.nih.gov]
Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hyperprolactinemia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Hyperprolactinemia from other Diseases Epidemiology [wikidoc.org]
Physiology, pathophysiology and clinical management. Philadelphia, Saunders, 1978, pp. 297-372. What is an eponym? An eponym is a word derived from the name of a person, whether real or fictional. [whonamedit.com]
Pathophysiology Tumors resembling chromophobe adenomas of the pituitary gland with eosinophilic granulation on tetrachrome staining. Clinical aspects Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica. [accesspediatrics.mhmedical.com]
Forbes taught sections of pathophysiology courses at Harvard Medical School and lectured on endocrine diseases at the Massachusetts General Hospital School of Nursing. Dr. [columbiamedicinemagazine.org]
Prevention
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]
Drugs such as letrozole and anastrozole can sindrome forbes albright used to prevent short stature in both males and females. [todaypdf.pw]
| Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies Case Studies Case #1 Acknowledgements The content on this page was first contributed by: C. [wikidoc.org]
Despite this positive data from the Women’s Health Initiative, the use of estrogen to prevent or treat osteoporosis is less prevalent now than 20 years ago. [tandfonline.com]
And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]