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Foreign-Body Reaction

Reaction Foreign Body


Presentation

  • Five of 21 cases presented with pain. Histopathologically, CHA presented as a diffuse mass of mauve-gray or beige, nonrefractile spherules, and PLA as rice- or spindle-shaped, geometric, refractile bodies within circumscribed nodules.[ncbi.nlm.nih.gov]
  • We present a case where we encountered an unusual intracerebral complication several months after endovascular treatment of a large left internal carotid artery aneurysm, and where brain biopsy revealed foreign body reaction to hydrophilic polymer fragments[ncbi.nlm.nih.gov]
  • The aim of this report is to present 7 new cases of foreign-body granulomas involving the oral and perioral tissues, after injection of biomaterials to achieve soft-tissue augmentation.[ncbi.nlm.nih.gov]
  • The authors describe a 34-year-old man who presented with a palpable tender mass on the lateral aspect of the left knee of 1 month's duration. He underwent posterior cruciate ligament and posterolateral corner reconstruction 3 years earlier.[ncbi.nlm.nih.gov]
  • The case of a 57-year-old woman who suffered a fall is presented. After a polymethyl malacrylate revision cranioplasty, she presented with signs, symptoms, and intraoperative findings consistent with postneurosurgical infection.[ncbi.nlm.nih.gov]
Cerebral Palsy
  • A 43-year-old woman with cerebral palsy and disabling spasticity underwent a series of 4 implantations of intrathecal baclofen pumps, performed by two teams.[ncbi.nlm.nih.gov]
Skin Patch
  • Skin patch tests were negative. Relocation of the system was followed by a relapse, while removal of the pump was followed each time by complete resolution of the symptoms.[ncbi.nlm.nih.gov]

Workup

  • […] surrounded by variable amounts of lymphocyte predominant chronic inflammation and reactive dermal fibrosis Foreign body is often refractile but may or may not be polarizable; examination with polarized light is useful component of granulomatous dermatitis workup[pathologyoutlines.com]
Foam Cell
  • The pathological evaluation of the biatrial device associated appositions revealed hytrophic heart muscle tissue with perifocal scarring and purulent abscess-forming, granulating and foam-cell including inflammatory foreign body reaction instead of the[ncbi.nlm.nih.gov]

Treatment

  • General practitioners and specialists should be aware of alternate treatment plans and treatment procedures and take these into consideration whenever there is a postoperative problem to be solved.[ncbi.nlm.nih.gov]
  • After two courses of treatment she developed painless facial nodules. A foreign body reaction to dermal fillers was suspected because the patient had received cosmetic treatment with dermal fillers 25 years previously.[ncbi.nlm.nih.gov]
  • A treatment strategy dependent on the stage can be implemented as a guideline to optimize functional and esthetic outcomes.[ncbi.nlm.nih.gov]
  • Flow diverter stents are new important tools in the treatment of large, giant, or wide-necked aneurysms. Their delivery and positioning may be difficult due to vessel tortuosity.[ncbi.nlm.nih.gov]
  • This means that initial marginal bone resorption around implants represents a reaction to treatment and is not at all a disease process.[ncbi.nlm.nih.gov]

Etiology

  • The few case reports describing pretibial cyst formation noted several graft types and fixation techniques, making it difficult to establish one etiology.[ncbi.nlm.nih.gov]
  • Since it began to be used, cases that simulate tumor recurrence have been described in neurosurgery, gastrointestinal, and cardiac surgery, forcing additional examinations to determine an etiology of foreign body granulomatous reactions. [1] , [2] , [[thoracicmedicine.org]
  • Is the etiology of pretibial cyst formation after absorbable interference screw use related to a foreign body reaction? Clin Orthop Relat Res . 2011; 469(4):1082–1088. doi:10.1007/s11999-010-1580-5 [CrossRef][healio.com]
  • MRI is impractical for routine foreign body detection in the ED but should be considered in cases of longstanding wounds or focal infections with unknown etiology in which the presence of a foreign body is being considered. [ 51 , 52] Ultrasonography[emedicine.medscape.com]

Epidemiology

  • In addition, the clinical and epidemiological profile of this condition is summarized, based on a review of the English-language literature of all previously described cases.[ncbi.nlm.nih.gov]
  • […] inflicted: tattoos, mercury, injected recreational drugs, food particles, injected mineral oil or paraffin (for attempted cosmesis) ( Clin Dermatol 1991;9:157 , Am J Dermatopathol 2014;36:409 , Dermatology 2014;228:14 , Facial Plast Surg 2014;30:615 ) Epidemiology[pathologyoutlines.com]
  • Recognition of these effects in patients is hampered by a lack of epidemiological studies. Keywords 6) Autoimmunity. 2007 Nov;40(7):512-20.[meshproblems.weebly.com]
Sex distribution
Age distribution

Pathophysiology

  • Varies widely depending on type of foreign material Sites Most commonly presents at site(s) of initial cutaneous injury Rare "migratory" granulomas are due to visible dermatologic lesions remote from initial site of injury ( Ann Diagn Pathol 2015;19:10 ) Pathophysiology[pathologyoutlines.com]
  • The pathophysiology of these extrusions is unclear, however the extrusions usually occur 2 months after placement [ 15 ].[jscholaronline.org]

Prevention

  • The purpose of this case report is to stress the importance of taking a proper history and the appropriate evaluation of diagnostic tests in order to prevent incorrect diagnosis and treatment.[ncbi.nlm.nih.gov]
  • Of these, delivery of dexamethasone throughout the implantation period is the most common method to prevent inflammation and fibrosis.[ncbi.nlm.nih.gov]
  • Medicated dressings of various compositions are commonly placed for prevention or management of dry socket (or alveolar osteitis, a common postoperative complication of tooth extraction) and may be a cause of foreign body reaction.[ncbi.nlm.nih.gov]
  • The site of ganciclovir implants in patients with immune recovery vitritis syndrome should be regularly inspected for eroding struts to prevent secondary endophthalmitis.[ncbi.nlm.nih.gov]
  • Gynaecological surgery techniques and instruments have advanced and there is increasing effort to reduce operative complications by preventing adhesion complications after surgery.[ncbi.nlm.nih.gov]

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