Sir, Mizuo phenomenon has been rarely reported in juvenile X-linked retinoschisis (XLR). 1 We report a case of XLR with peripheral Mizuo phenomenon 2 which presented as isolated foveal schisis. [nature.com]

Case presentation We present a case of a 17-year-old caucasian male with foveal and peripheral schisis, along with Mizuo-Nakamura phenomenon. RS1 sequencing led to the discovery of an in-frame deletion not previously described in the literature. [bmcmedgenet.biomedcentral.com]

However, disease is commonly presented with reading difficulties due to the foveoschisis in school-age children, it can be diagnosed with nystagmus or strabismus in infancy. [ijo.in]

X-linked retinoschisis may also present as spontaneous vitreous hemorrhage or retinal detachment. [eyewiki.aao.org]

• Retinal Pigmentation

  Figure 4: SD-OCT of the right macula shows significant atrophy of the retina with loss of the outer retinal layer architecture, but no retinal schisis. There is pigment clumping and irregular retinal pigment epithelium. [westcoastretina.com]

  The broad area of flat central tissue on OCT suggests that fovealschisis may collapse with subsequent alterations of the retinal pigment epitheliumand overlying retina. [jamanetwork.com]

  The diagnosis may be difficult because of retinal pigment epithelium (RPE) and choroidal atrophy. Biomicroscopic diagnosis of MH in highly myopic eyes without retinal detachment is sometimes difficult. [touchophthalmology.com]

• Strabismus

  Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus, 17 (2), pp. 225-7. doi:10.1016/j.jaapos.2012.11.016. Yang FP, Willyasti K, Leo SW. [unboundmedicine.com]

  However, disease is commonly presented with reading difficulties due to the foveoschisis in school-age children, it can be diagnosed with nystagmus or strabismus in infancy. [ijo.in]

  Congenital x-linked retinoschisis is typically diagnosed in males between the ages of 3 months and school age with symptoms that include crossed eyes (strabismus), abnormal eye movements (nystagmus) and “lazy eye” (amblyopia). [retinalmd.com]

  Patients typically present complaining of difficulty in school, although younger patients may present earlier with strabismus or nystagmus. Visual acuity may range from 20/20 to blindness, and depends on the amount and area of schisis. [eyewiki.aao.org]

  The disorder is also associated with axial hyperopia, posterior subcapsular cataract and strabismus. Fluorescein angiography shows minimal or no leakage as opposed to cystoid macular edema. [disorders.eyes.arizona.edu]

• Visual Impairment

  X-linked juvenile retinoschisis is a rare hereditary retinal disease characterized by a tangential splitting of the neurosensory retina which may cause early-onset visual impairment. [ncbi.nlm.nih.gov]

  Visual impairment in patients with macular retinoschisis may be variable. [onlinelibrary.wiley.com]

  The presence of blood in the vitreous body causes further visual impairment. The vitreous body degenerates and may eventually separate from the retina. The entire retina may also separate from underlying tissue layers causing retinal detachments. [retinaaustralia.com.au]

  Methods We reviewed the records of 14 consecutive patients (53–77 years of age; 16 eyes) with progressive visual impairment as a result of myopic RS or FD. [link.springer.com]

• Night Blindness

  Neither patient had a family history of low vision, night blindness, or retinal detachment. Visual acuity in the affected eyes was 20/50 and 20/25, respectively. Both fellow eyes had normal fundi, except for mild myopic changes. [moh-it.pure.elsevier.com]

  Presentation - poor night vision as a result in a delay or an inability to achieve normal dark-adapted rod thresholds. Patients have night blindness, reduced acuity, high myopia, nystagmus and strabismus. [patient.info]

  However, a similar ERG pattern can be seen in other hereditary and acquired retinal disorders, notably, congenital stationary night blindness. [institut-vision.org]

• Retinal Cyst

  cysts 2016 2017 2018 2019 Non-Billable/Non-Specific Code Applicable To Pseudocyst of retina Other retinoschisis and retinal cysts Approximate Synonyms Bullous retinischisis Bullous retinoschisis Flat retinoschisis Primary retinal cyst Pseudocyst of retina [icd10data.com]

  The inner retinal layers are missed in the right side of the image, while in the left side are still present but detached from the outer retina Spectral Domain Optic Coherence Tomography (SD OCT, Topcon 3D-2000) showed pronounced inner retinal cysts in [bmcmedgenet.biomedcentral.com]

  Detachment Hereditary or Acquired Retinoschisis Central Serous Chorioretinopathy Choroidal Melanoma Retinal cyst CLINICAL COURSE The patient underwent an uncomplicated clinical course. [eyerounds.org]

  Multiple subretinal demarcation lines and secondary retinal cysts, often found in the patients with dialysis, indicate that the retinal detachment is long-standing. [doctorlib.info]

• Nystagmus

  However, disease is commonly presented with reading difficulties due to the foveoschisis in school-age children, it can be diagnosed with nystagmus or strabismus in infancy. [ijo.in]

  Patients typically present complaining of difficulty in school, although younger patients may present earlier with strabismus or nystagmus. Visual acuity may range from 20/20 to blindness, and depends on the amount and area of schisis. [eyewiki.aao.org]

  Other symptoms include night blindness, an inability of both eyes to focus on an object (strabismus) and roving, involuntary eye movements (nystagmus). In about half of the cases, peripheral (side) vision is also affected. [ieek1eoawdvdq7e.changeip.net]

  Juvenile retinoschisis is a congenital X-linked recessive retinal disorder.Patients may develop nystagmus, decreased central vision, or strabismus. [jamanetwork.com]

  Patients have night blindness, reduced acuity, high myopia, nystagmus and strabismus. There are two major types - the complete form and the incomplete form. [patient.info]

Ty Bollinger "Cancer Truths" and … Juvenile Retinoschisis Workup: Imaging Studies, Other ... ★ ★ ☆ ☆ ☆ January 21, 2019 by Kevin Miller Familial foveal retinoschisis (FFR) is an extremely rare autosomal recessive disorder first described by Lewis et al [ieek1eoawdvdq7e.changeip.net]

Although there is no proven guideline for both the laser prophylaxis and the treatment of retinoschisis, laser photocoagulation, cryotherapy, scleral buckle, and parsplana vitrectomy are considered as the main treatment options especially in cases with [ijo.in]

Comparison of central foveal thickness and visual acuity before and after treatment with topical brinzolamide Patient Treatment duration, months Central foveal thickness Best-corrected visual acuity Before treatment, mm After treatment, mm Differencea [docslide.net]

research treatments, prevention, and prognosis. [llh8auadq0hcv.changeip.net]

However, to prevent the development of FTMH and subsequent MH RD, early surgical treatment may be necessary. In this article we discuss when and how to perform pars plana vitrectomy for the treatment of MTM. [retinatoday.com]

We report a case of bilateral foveal retinoschisis before and after treatment with topical dorzolamide, which was misdiagnosed as bilateral hyperopic amblyopia. [ncbi.nlm.nih.gov]

Traumatic macular retinoschisis is a rare clinical entity which carries poor visual prognosis. Financial Disclosure None Comments - [euretina.org]

Prognosis - there is no progression. [patient.info]

Local Biometric Features and Visual Prognosis after Surgery for Treatment of Myopic Foveoschisis. Retina. Mar 13 2013. [eyewiki.aao.org]

Prognosis - Retinoschisis of Fovea Not supplied. Treatment - Retinoschisis of Fovea Eye Health Specialists (Ophthalmology): o Ophthalmology (Eye Specialist) Resources - Retinoschisis of Fovea Not supplied. [checkorphan.org]

Treatment and Prognosis: The foveal and peripheral retinal splitting that occurs in schisis cannot be treated, but secondary complications may require treatment. [pediatricrrf.org]

[…] and Pathogenesis Although the exact etiology is unknown, there is no evidence to suggest a genetic, vascular, or nutritional etiologic component[3]. [eyerounds.org]

★ ★ ★ ☆ ☆ January 11, 2019 by George Wilson “Degenerative Retinoschisis is very common with a prevalence of up to 7 percent in normal persons.Its etiology is unknown. [llh8auadq0hcv.changeip.net]

Etiology and pathogenesis The etiology of degenerative retinoschisis is poorly understood. Genetic, vascular, nutritional, or tractional mechanisms do not seem to be implicated in the pathogenesis of the condition. [institut-vision.org]

★ ★ ★ ☆ ☆ January 14, 2019 by Robert Collins “Degenerative Retinoschisis is very common with a prevalence of up to 7 percent in normal persons.Its etiology is unknown. [ieek1eoawdvdq7e.changeip.net]

Epidemiology, onset & clinical features Epidemiology Degenerative retinoschisis affects about 5-7% of the adult population. Occurrence in up to 22% of individuals older than 40 years has been reported. Both genders are equally affected. [institut-vision.org]

Epidemiology Reported prevalence of disease varies widely due to population-based RS studies, difficulty of observing lesions due to its peripheral location, and the fact that most patients are asymptomatic. [eyerounds.org]

Epidemiology of high myopia and myopic retinopathy There have been no epidemiological studies specifically evaluating the prevalence of MF. [nature.com]

Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any [books.google.de]

Pathophysiology X-linked retinoschisis is linked to mutations in RS1 on Xp22.1. [eyewiki.aao.org]

Pathophysiology The source of fluid and definitive pathogenesis of papillary schisis and detachment associated with optic disc anomalies, or in glaucomatous papillary detachments, as in this case, are unclear. [journal.opted.org]

Laser treatment or vitrectomy prevented this in three patients. A seventh patient is being monitored by periodic spectral domain optical computerized tomography. [pubmed.ncbi.nlm.nih.gov]

Prevention How can I prevent retinoschisis? You can’t prevent retinoschisis. There’s no known cause of acquired retinoschisis. [my.clevelandclinic.org]

Prevention - Retinoschisis of Fovea Not supplied. Diagnosis - Retinoschisis of Fovea Not supplied. Prognosis - Retinoschisis of Fovea Not supplied. [checkorphan.org]

2019 by Richard King Familial foveal retinoschisis symptoms, causes, diagnosis, and treatment information for Familial foveal retinoschisis (Retinoschisis of Fovea) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention [llh8auadq0hcv.changeip.net]

Also, in these patients apparent complete posterior vitreous detachment (PVD) confirmed by biomicroscopy does not prevent vitreous remnants adhering to theretina, since vitreoschisis and a posterior vitreous cortex adherence has been found to persist. [touchophthalmology.com]