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Fungal Keratitis

Keratomycosis


Presentation

  • Patients presenting with concurrent bacterial/viral keratitis, systemic illness, prior ocular pathology, or those without a minimum follow-up of 3 months were excluded.[ncbi.nlm.nih.gov]
Aspiration
  • During irrigation of the anterior chamber with amphotericin B, aspirated corneal infiltrations were submitted for culture and metagenomic analysis.[ncbi.nlm.nih.gov]
  • The rigorous review process does not allow any compromise in quality It is indexed in many indexing agencies and the articles are available under creative commons licence free of cost The frequency of publication supports many aspiring authors from India[jcdr.net]
  • The rapid identification of the causative microorganism in cultures and stains of corneal scrapes, vitreous aspirates, and/or corneo-scleral biopsy is crucial in the successful management of keratitis.[pubs.sciepub.com]
Insect Bite
  • Herein, we report a 61-year-old ethnic Han Taiwanese male who had suffered from pain with burning and foreign body sensation after an insect bite on his left eye.[ncbi.nlm.nih.gov]
Corneal Infiltrate
  • A 40-year-old man developed pain, decreased vision, and a corneal infiltrate 10 days after laser-assisted subepithelial keratectomy. Treatment with conventional topical and systemic antibiotic agents did not improve the symptoms.[ncbi.nlm.nih.gov]
Corneal Infiltrate
  • A 40-year-old man developed pain, decreased vision, and a corneal infiltrate 10 days after laser-assisted subepithelial keratectomy. Treatment with conventional topical and systemic antibiotic agents did not improve the symptoms.[ncbi.nlm.nih.gov]
Arcus Senilis
  • If cases of arcus senilis are studied regularly with optical coherence tomography, the Singh canal and Schlemm canal will be visualized as being connected through ”aqueducts.”[emedicine.com]
Corneal Deposit
  • Among the patients, 71% had persistent corneal deposit sequelae. Four patients lost the eyeball. CONCLUSION: Corneal traumatism was the principal risk factor for fungal keratitis in young and middle-aged farmers.[ncbi.nlm.nih.gov]
Conjunctival Nodule
  • Here, the principal side effect is that these injections may result in permanent yellowing of the cornea as well as salmon-colored conjunctival nodules at the site of injection.[healio.com]

Workup

Trichophyton Mentagrophytes
  • PubMed Google Scholar Shenoy R, Shenoy UA, Al Mahrooqui ZH: Keratomycosis due to Trichophyton mentagrophytes. Mycoses. 2003, 46: 157-158. 10.1046/j.1439-0507.2003.00863.x.[bmcophthalmol.biomedcentral.com]

Treatment

  • METHODS: In total, 45 eyes with smear-confirmed fungal keratitis with hypopyon were randomized into three treatment groups: Group I (topical antifungal treatment   oral antifungal); Group II (topical antifungal treatment   ICAMB   oral antifungal); and[ncbi.nlm.nih.gov]

Prognosis

  • This cost-effective treatment modality proved to be significant in impeding the progression of this potentially blinding disease and improving visual prognosis.[ncbi.nlm.nih.gov]

Etiology

  • OBJECTIVE: The aim of this study was to determine the etiological agents, predisposing factors and therapy of keratomycosis in our region.[ncbi.nlm.nih.gov]

Epidemiology

  • KEYWORDS: Epidemiology; Fungi; Identification; Keratitis; Multiplex PCR[ncbi.nlm.nih.gov]
  • Upon acceptance Copyright on any research article is transferred in full to the Confederation of Epidemiological Associations (CEA) and International Nepal Epidemiological Association (INEA).[nepjol.info]
  • Epidemiological profile of fungal keratitis in urban population of West Bengal, India.[ojoonline.org]
  • Epidemiological characteristics and laboratory diagnosis of fungal keratitis.[ijo.in]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The infection probably starts when the epithelial integrity is broken either due to: 1-trauma. 2- ocular surface disease . 10.[slideshare.net]
  • A greater understanding of the pathophysiologic mechanisms highlight new areas where therapeutics may be directed from both the host and fungal standpoints.[link.springer.com]
  • Pathophysiology Many fungal organisms associated with ocular infections are ubiquitous, saprophytic organisms and have been reported as causes of infection only in the ophthalmic literature.[emedicine.com]
  • The American Academy of Ophthalmology's Pathology Atlas contains virtual microscopy images of tissue samples with the following: Aspergillus Keratitis Fungal Keratitis Pathophysiology The infection probably starts when the epithelial integrity is broken[eyewiki.aao.org]

Prevention

  • AMT is effective in promoting epithelialization and preventing corneal perforations in acute fungal keratitis, and there is no risk of rejection.[ncbi.nlm.nih.gov]
  • Prevention of trauma with vegetable / organic matter, particularly in agricultural workers while harvesting can reduce the incidence of fungal keratitis.[en.wikipedia.org]

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