We present a case of sepsis with Saccharomyces cerevisiae fungemia during treatment with Saccharomyces boulardii. Case: A 61 years old male was admitted to the hospital. [aspergillus.org.uk]

A 5-month-old boy presented to us with fever and cough for 15 days and one episode of generalized tonic clonic convulsion. He had oral thrush at 1 month and otitis media at 2 months of age. Birth weight was 2.9 kg. [indianpediatrics.net]

The authors present a case report of a 79-year-old woman with rheumatoid arthritis, who after a bowel resection developed S boulardii fungemia. [casereports.bmj.com]

Bruun, Department of Clinical Microbiology, Statens Seruminstitut, Artillerivej 5, DK‐2300 Copenhagen S, Denmark Tel: 4532 683 371 Fax: 4532 683 873 Search for more papers by this author First published: December 1995 Cited by: 1 Abstract Objective: To present [onlinelibrary.wiley.com]

Yet no consensual therapeutic guidelines are presently available. [dovepress.com]

• Fatigue

  Many symptoms may be associated with fungemia, including pain, acute confusion, chronic fatigue, and infections. [en.wikipedia.org]

• Anemia

  Previous studies have reported anemia, probably hemolytic in origin, in adults receiving capsofungin. [nature.com]

  The largest previous report was a collated review of 62 cases. 6 Approximately 90% of cases have occurred in patients with acute leukemia or aplastic anemia or bone marrow transplant recipients, and very few cases have been reported in patients who did [jamanetwork.com]

• Pathologist

  In a clinical setting, in which the pathologist would be reviewing the slide as an unknown, these occasional yeast forms could easily be missed or dismissed as contaminants by a pathologist. [archivesofpathology.org]

  MD, Clinical Pathologist, Belo Horizonte, MG, Brazil Summary Introduction: The prevalence of nosocomial fungemia has increased worldwide, and mortality caused by this disease is high. [scielo.br]

• Wound Infection

  infection, catheter infection, peritonitis, phlebitis, urinary tract infection in immunocompromised patients. [ijmm.org]

• Sputum

  Sputum smears were repeatedly negative for acid-fast bacilli. Several blood cultures drawn within the first 3 days remained negative. Urinalysis was negative as were antigenuria for Legionella pneumophila and Streptococcus pneumoniae. [bmcinfectdis.biomedcentral.com]

  C. norvegensis was first isolated in Norway from the sputum of three patients with asthma in 1954. 6 The first described clinically relevant infection by this pathogen was in a renal transplant recipient who developed C. norvegensis peritonitis associated [elsevier.es]

• Pleural Effusion

  Saccharomyces cerevisiae (also known as brewer’s or baker’s yeast) has been reported as a cause of fungemia, peritonitis, pleural effusion, esophagitis, endocarditis and arthritis in immunocompromised patients. [indianpediatrics.net]

• Tachypnea

  On presentation, he was lethargic, and had tachycardia and tachypnea. He had oral thrush, diffuse greyish rash all over body, and hepatosplenomegaly. Investigations showed lympho-cytopenia and thrombo-cytpoenia. HIV ELISA was negative. [indianpediatrics.net]

• Somnolence

  The patient presented in shock, with somnolence, exsiccosis, fever, dyspnea, nontender abdomen, vivid bowel sounds. Laboratory values (CrP 299 mg/l, leukocytes 17,9 GPt/l) indicated a severe infection. [aspergillus.org.uk]

Blood cultures from a central catheter source have a better yield than those from peripheral sites. [3] A positive peripheral blood smear, as seen in this case, is rare. [4] Malassezia fungemia should be considered in the workup of sepsis in patients [medscape.com]

• Staphylococcus Aureus

  Lavage fluid culture was positive for Staphylococcus aureus (10 4 CFU/mL) and Candida spp. (10 3 CFU/mL). The latter contained two populations that were first identified as C. albicans and a C. parapsilosis. [bmcinfectdis.biomedcentral.com]

  aureus in 5 cases (4 of which were detected at centers using the Bactec system), Lactobacillus or Bacillus spp. in 5 cases (all of which were detected at centers using the Bactec system), streptococci in 4 cases (2 of which were detected at centers using [jcm.asm.org]

  aureus in four, S. epidermidis in three, group B Streptococcus in one and polymicrobial bacteremia in one). [nature.com]

• Hepatocellular Carcinoma

  Case report In June 2008, a 61-year-old man underwent liver transplantation because of an end-stage liver disease caused by hepatitis C and B viruses coinfection and hepatocellular carcinoma. [elsevier.es]

• Pleural Effusion

  Saccharomyces cerevisiae (also known as brewer’s or baker’s yeast) has been reported as a cause of fungemia, peritonitis, pleural effusion, esophagitis, endocarditis and arthritis in immunocompromised patients. [indianpediatrics.net]

After 13 days of treatment, the patient developed fungemia with S boulardii. Treatment with Sacchaflor was immediately discontinued and the patient was successfully treated with amphotericin B. [casereports.bmj.com]

Candidemia persisted in all patients despite treatment with amphotericin B. [nature.com]

Mortality by species and initial antifungal treatment for the 278 patients receiving antifungal treatment DISCUSSION This study has revealed several important issues concerning the epidemiology, diagnostics, and treatment of fungemia, with implications [jcm.asm.org]

After 6 months of antiretroviral treatment, his HIV viral load was undetectable and his CD4 count was 255 cells/mm 3. [journals.lww.com]

Clinical cure was obtained after treatment was switched to voriconazole. [bmcinfectdis.biomedcentral.com]

[…] to: navigation, search Fungemia Microchapters Home Patient Information Overview Historical Perspective Pathophysiology Causes Differentiating Fungemia from other Diseases Epidemiology and Demographics Risk Factors Natural History, Complications and Prognosis [wikidoc.org]

Due to intrinsic resistance to echinocandins, poor susceptibility to polyenes, and preferred occurrence in immunocompromised patients, such infections are often of poor prognosis. Yet no consensual therapeutic guidelines are presently available. [dovepress.com]

Multiple logistic regression analysis identified that persistent neutropenia ( P .02) and septic shock ( P .002) were the only significant multiple predictors for a poor prognosis. [jamanetwork.com]

Most patients have involvement of multiple organs and the prognosis is poor, despite optimal treatment. [13] [14] Questions To access free multiple choice questions on this topic, click here. References 1. [ncbi.nlm.nih.gov]

Although the detection of the etiologic agents of fungal infection is difficult, it has been shown that blood culture media for mycobacteria are more effective for the detection of fungemia than media for aerobes and anaerobes. [jstage.jst.go.jp]

26 patients with fungemia and cancer treated with chemotherapy (group A) were compared to 25 patients with fungemia and cancer treated with surgery (group B), to assess differences in etiology, risk factors and outcome. [tandfonline.com]

Etiology Candida albicans is the most common cause of candidemia, representing 35% to 60% of isolates. [ncbi.nlm.nih.gov]

[…] of candidemia has been reported as 72 to 290 infections per million, 30 to 66 infections per million in the case of C. neoformans and 12 to 34 infections per million for Aspergillus sp. 7 Over 17 different species of Candida have been identified as etiologic [academic.oup.com]

Rapid detection of the etiological agent causing the infection is of fundamental importance to allow early adjustment of treatment and hence, the reduction of hospital mortality by fungemia. 4 The HC-UFMG is a teaching hospital that offers public and [scielo.br]

Candida glabrata Fungemia Export citation Request permission Abstract Copyright COPYRIGHT: The Society for Healthcare Epidemiology of America 1999 Infection Control & Hospital Epidemiology ISSN: 0899-823X EISSN: 1559-6834 URL: /core/journals/infection-control-and-hospital-epidemiology [cambridge.org]

Li Y,Du M,Chen LA,Liu Y,Liang Z,, Mycopathologia, 2016 Mar 19 [PubMed PMID: 26994763] [3] Epidemiology, risk factor, species distribution, antifungal resistance and outcome of Candidemia at a single French hospital: a 7-year study., Tadec L,Talarmin [statpearls.com]

Epidemiology of endemic systemic fungal infections in Latin America Med Mycol 2011 49 785 798 25. Epidemiology surveillance of fungal infection Med Mycol 2000 38 S1 173 182 26. [academic.oup.com]

Epidemiology of bloodstream infections at a cancer center. Sao Paulo Med J. 2000; 118(5):131-8. [ Links ] 22 Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. [scielo.br]

Epidemiology Candidemia is the most common fungal bloodstream infection, and possibly the fourth most common all-type bloodstream infection seen in the intensive care unit setting [1]. [ncbi.nlm.nih.gov]

Jump to: navigation, search Fungemia Microchapters Home Patient Information Overview Historical Perspective Pathophysiology Causes Differentiating Fungemia from other Diseases Epidemiology and Demographics Risk Factors Natural History, Complications and [wikidoc.org]

(especially if repeated laparotomies or anastomotic leakage is present), malignancy (solid organ and hematologic), acute necrotizing pancreatitis, organ transplant recipients, and total parenteral nutrition are other major risk factors. [3] [4] [7] Pathophysiology [ncbi.nlm.nih.gov]

A genetically very similar subtype, S boulardii, is used in a probioticum (Sacchaflor) to prevent antibiotic-associated diarrhoea and in the treatment of recurrent Clostridium difficile associated diarrhoea. [casereports.bmj.com]

Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. [wwwnc.cdc.gov]

Differentiating Fungemia from other Diseases Epidemiology and Demographics Risk Factors Natural History, Complications and Prognosis Diagnosis History and Symptoms Physical Examination Laboratory Findings Other Diagnostic Studies Treatment Medical Therapy Prevention [wikidoc.org]

Conclusion: Due to the high relative prevalence of fungal infections in our study, it is necessary to take precautions for fungal infection prevention and choose the best way management to obtain optimal results in these patients. [ FULL TEXT ] [ PDF [advbiores.net]

Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii : a prospective study. Gastroenterology 1989; 96:981–8. 7. Pothoulakis C, Kelly CP, Joshi MA, et al. [journals.lww.com]