To our knowledge, F. nucleatum infection presenting with multiple liver masses and Trousseau-like syndrome has not been reported earlier. [ncbi.nlm.nih.gov]

Nucleoside monophosphate kinases for all types of nucleotides are present. [dx.doi.org]

• Intravenous Drugs

  A case of endocarditis due to Fusobacterium nucleatum in an intravenous drug abuser is reported, accompanied by a review of the literature. [ncbi.nlm.nih.gov]

• Chronic Infection

  The most important carcinogenesis mechanisms of F. nucleatum are chronic infection, interaction of cell surface molecules of these bacteria with immune system and stromal cells, immune evasion and immune suppression. [ncbi.nlm.nih.gov]

• Disability

  Multiple brain abscesses are serious neurological problems with high mortality and disabling morbidity. The frequency is rising as a result of AIDS and the increasing number of immunocompromised patients. [ncbi.nlm.nih.gov]

• Aspiration

  The usefulness of real-time ultrasound in fine needle aspiration diagnosis of a peripheral lung lesion is demonstrated, and the role of Liu's stain in FNAC is emphasized. [ncbi.nlm.nih.gov]

• Orthopnea

  A pericardial effusion was diagnosed by echocardiography in a 49 year old man who suffered acute cough, orthopnea, and chest pain. Because of a positive tuberculin skin test, mycobacteria were initially suspected as the cause of the pericarditis. [ncbi.nlm.nih.gov]

• Acute Cough

  A pericardial effusion was diagnosed by echocardiography in a 49 year old man who suffered acute cough, orthopnea, and chest pain. Because of a positive tuberculin skin test, mycobacteria were initially suspected as the cause of the pericarditis. [ncbi.nlm.nih.gov]

• Thrombosis

  We report the first description of portal and mesenteric vein thrombosis associated with suppurative mesenteric adenitis in a 71-year-old woman. [ncbi.nlm.nih.gov]

• Chest Pain

  A pericardial effusion was diagnosed by echocardiography in a 49 year old man who suffered acute cough, orthopnea, and chest pain. Because of a positive tuberculin skin test, mycobacteria were initially suspected as the cause of the pericarditis. [ncbi.nlm.nih.gov]

• Liver Mass

  To our knowledge, F. nucleatum infection presenting with multiple liver masses and Trousseau-like syndrome has not been reported earlier. [ncbi.nlm.nih.gov]

• Meningism

  We describe our experience in the management of this case of anaerobic meningitis and the unusual complication of ischemic stroke; this case suggests that more aggressive therapy in addition to empirical antibiotics may be warranted. [ncbi.nlm.nih.gov]

• Neck Stiffness

  A 59-year-old woman developed signs and symptoms of diffuse brain dysfunction including fever and neck stiffness. A brain CT scan demonstrated nine contrast-enhancing ring-shaped lesions. [ncbi.nlm.nih.gov]

The ensuing workup revealed a posterior oral cavity tumour (squamous cell carcinoma), Fusobacterium nucleatum bacteraemia and liver abscesses. [ncbi.nlm.nih.gov]

• Pericardial Effusion

  The pericardial effusion failed to resolve, however, and pericardiectomy was performed. Culture of the pericardial fluid yielded pure Fusobacterium nucleatum growth. [ncbi.nlm.nih.gov]

• Polyps

  KEYWORDS: BRAF; Fusobacterium; KRAS; MLH1; colon polyp; colorectum; dysplasia; miR-31; microbiome; serrated neoplasia pathway [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

  Statistics from Altmetric.com colorectal cancer intestinal bacteria We read with great interest the article by Flemer et al, which suggests that analysis of the oral microbiota could potentially be used as a screening method for colorectal cancer (CRC) and polyp [gut.bmj.com]

• Liver Biopsy

  A 48-year-old man presented with fevers, chills, weight loss, multiple liver masses, and several superficial and deep venous thromboses in lower extremities. Cancer work up was negative. A liver biopsy grew Fusobacterium nucleatum. [ncbi.nlm.nih.gov]

F. nucleatum treatment significantly altered lumen microbial structures, with increased Tenericutes and Verrucomicrobia (opportunistic pathogens) (P < 0.05 = in wild-type C57BL/6 and mice with DMH treatment). [ncbi.nlm.nih.gov]

Annexin A1 is specifically expressed in colorectal cancer cells and is a predictor of poor prognosis. The Fusobacterium nucleatum FadA adhesin up‐regulates Annexin A1 expression through E‐cadherin. [embor.embopress.org]

Regarding the immune response in colorectal cancer, high levels of infiltrating T-cell subsets (i.e., CD3+, CD8+, CD45RO+, and FOXP3+ cells) have been associated with better patient prognosis. [ncbi.nlm.nih.gov]

Characteristics of Fn -associated CRC were identified through studies using human CRC cohorts and include right-sided colon location, CpG island methylation phenotype (CIMP)-high, high level of microsatellite instability (MSI-H), and poor patient prognosis [jstage.jst.go.jp]

The CD45RO + -cell and FOXP3 ± (lo) T cell biomarkers are associated with a favorable prognosis in F. nucleatum -positive CRC, while the miR-21, LncRNA PANDAR, and TAMs CD68 + /iNOS − biomarkers are associated with a poor clinical prognosis of F. nucleatum [wjgnet.com]

Clinicians should be aware that F. nucleatum could be the etiologic agent of hematogenous osteomyelitis of a long bone in an immunocompetent patient. [ncbi.nlm.nih.gov]

Etiology and Pathology The exact cause of cancrum oris is unknown but there appear to be three factors instrumental in its development: (1) a predisposing state of debilitation and malnutrition; (2) a specific infection of the mouth usually due to a spirochete [isradiology.org]

KEYWORDS: CANCER EPIDEMIOLOGY; COLONIC BACTERIA; COLONIC MICROFLORA; COLORECTAL CANCER; INTESTINAL BACTERIA Conflict of interest statement Dr. [ncbi.nlm.nih.gov]

Article Navigation From the Departments of Obstetrics and Gynecology, Epidemiology, and Medicine, University of Washington, Seattle, Washington Reprints or correspondence: Dr. Sharon L. [doi.org]

Chan School of Public Health, Boston, Massachusetts, USA 3 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA 4 Department of Biostatistics, Harvard T.H. [gut.bmj.com]

"Respiratory infection by Corynebacterium striatum: epidemiological and clinical determinants". New Microbes and New Infections. 2 (4): 106–14. doi:10.1002/nmi2.48. PMC 4184579. PMID 25356355. ^ a b Daisuke U, Oishi T, Yamane K, Terada K (2017). [en.wikipedia.org]

Further studies are warranted to determine if F. nucleatum ssp. animalis could be a novel target for colorectal cancer prevention and treatment. Cancer Prev Res; 10(7); 398-409. ©2017 AACR. ©2017 American Association for Cancer Research. [ncbi.nlm.nih.gov]

Capable of arresting fibroblast growth, thus preventing wound healing and aiding penetration of the gingival epithelium. [genome.jp]