Presentation
A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories. [books.google.com]
The condition may present with cardiovascular problems such as myocardial or cerebral ischaemia. For this reason, it may be justifiable to venesect the patient. [babylon-software.com]
Immune System
- Splenomegaly
Gaisböck syndrome (redirected from Gaisbock syndrome) pol·y·cy·the·mi·a hy·per·to·n'i·ca polycythemia associated with hypertension, but without splenomegaly. [medical-dictionary.thefreedictionary.com]
He described 18 male patients in whom hypertension was associated with an elevated red cell count and Hb but without splenomegaly. He named the condition polycythemia hypertonica. [thebloodproject.com]
[…] polycythaemia associated with hypertension, but without splenomegaly. Synonyms: Gaisbock's syndrome. American spelling: polycythemia hypertonica (05 Mar 2000) [mondofacto.com]
Entire Body System
- Hypoxemia
|Erythrocytosis due to tissue hypoxemia (disorder)|Gaisbock syndrome|Gaisbock's syndrome|Gaisbock's syndrome (disorder)|High oxygen affinity haemoglobin polycythaemia|High oxygen affinity hemoglobin polycythemia|High oxygen affinity hemoglobin polycythemia [averbis.com]
ABG revealed hypoxemia with pO2 (33.9 mmhg). [medicaldialogues.in]
ABG showed hypoxemia with pO2 (33.9 mmhg). Other blood studies, including blood u r e a n i t r o g e n, c r e a t i n i n e, electrolytes, liver chemistries and thyroid stimulating hormone were within normal limits. [japi.org]
[…] mechanisms help explain the pathophysiology underlying Gaisbock's observations, and these include psychiatric disorders resulting in chronic stress, volume contraction secondary to diuretics and hypertension, and obstructive sleep apnea with nocturnal hypoxemia [pubmed.ncbi.nlm.nih.gov]
The finding of significant hypoxemia in the supine position in all patients in this study suggests that postural hypoxemia may be a frequent cause of an elevated red cell volume. [amjmed.com]
- Plethora
Andral1 in 1843 observed that plethora is more frequently constitutional than acquired. [jamanetwork.com]
Abstract The syndrome of plethora without splenomegaly, leukocytosis, or thrombocytosis was described by Gaisböck in 1905. It was reevaluated in 25 patients through the study of numerous hematologic and biochemical parameters. [ncbi.nlm.nih.gov]
Vegetative, Autonomic, Endocrine Disorders Cushing's disease/Syndrome Polycythemia, stress (Gaisboeck) 12.Reference to Organ System Acne vulgaris (acne) Acne rosacea Seborrhea dermatitis/dandruff disorder Seborrhea/facial Polycythemia/Secondary polycythemia Plethora [doctorforhealth.blogspot.com]
Angiology 29(7): 520-533 1978 ISSN/ISBN: 0003-3197 PMID: 686487 DOI: 10.1177/000331977802900703 Accession: 040191146 The syndrome of plethora without splenomegaly, leukocytosis, or thrombocytosis was described by Gaisböck in 1905. [eurekamag.com]
- Developmental Disorder
Homocystinuria/homocystinemia 7.Deficiency Disorders Pellagra/niacin deficiency 8.Congenital, Developmental Disorders Plethora of newborn Bloom syndrome 9.Hereditary, Familial, Genetic Disorders Polycythemia, hereditary benign 10.Anatomic, Foreign Body [doctorforhealth.blogspot.com]
Cardiovascular
- Hypertension
This review revisits Gaisbock syndrome based on recent literature, and will highlight contemporary studies that have established an association between erythrocytosis and hypertension and associated risk factors. [pubmed.ncbi.nlm.nih.gov]
Our patient had four risk factors for Gaisbock's syndrome - hypertension, diuretic therapy, physical and emotional stress, and obesity; of these, hypertension (particularly diastolic hypertension) appears to be the most significant contributor to the [clinmedjournals.org]
Gaisböck syndrome (redirected from Gaisbock syndrome) pol·y·cy·the·mi·a hy·per·to·n'i·ca polycythemia associated with hypertension, but without splenomegaly. [medical-dictionary.thefreedictionary.com]
male sex, smoking and diuretic therapy; of these, hypertension appears to be the most significant contributor to the polycythemia of Gaisbock’s syndrome.2 In this regard, Emamian and associates studied 9,808 individuals with essential hypertension and [japi.org]
Skin
- Dermatitis
contact Eczema/Dermatitis, atopic Dermatomyositis Dermatomyositis/childhood type Drug induced Lupus (SLE)- Lupus erythematosis, systemic Mixed connective tissue disease (MCTD)/Undifferentiated Scleroderma, progressive systemic Dermatitis, neutrophilic [doctorforhealth.blogspot.com]
Recovery from the "hemolytic effects" of arsenic leads to a compensatory condition "polycythemia" an excess of red blood cells, in patients with normal RBC metabolism http://www.origen.net/tox.html Possible effects of arsenic toxicity include hair loss, dermatitis [curezone.org]
Dubin-Johnson デュビン・ジョンソン Dubin-Johnson syndrome デュビン・ジョンソン症候群 Dubos デュボス Dubos medium デュボス培地 Duchenne デュシェンヌ Duchenne muscular dystrophy デュシェンヌ型筋ジストロフィー GuillaumeBenjamin Amand Duchenne (1806 - 1875) French neurologist Duhring デューリング Duhring's herpetiform dermatitis [jams.med.or.jp]
- Eruptions
Seborrhea-like skin eruption typically present. EM: Rod shaped inclusions in Langerhans cells (Birbeck granules) Prognosis: Relatively benign course. Lesions spontaneously regress in 50% and in 50% cured by chemoRx. [pathologyexpert.com]
Psychiatrical
- Suggestibility
— We suggest not testing for JAK2 mutation and/or bone marrow examination in all patients with polycythemia. [medilib.ir]
Neurofibromatosis or café-au-lait skin spots can suggest possible coexistent phaeochromocytoma (2.4A-C). [thoracickey.com]
Classical findings, when coexistent with other suggestive hematologic parameters, help support a diagnosis of polycythemia vera.[5] Strongly suggestive findings include a hypercellular marrow with erythroid hyperplasia and subtle megakaryocytic atypia [statpearls.com]
Frohlich Medicine JAMA 1974 Findings strongly suggest that "stress" polycythemia should not be considered a "benign" condition meriting therapy with phlebotomy or tranquilizing drugs, and patients with arterial pressure elevation should be treated vigorously [semanticscholar.org]
She now presents with a clinical scenario that suggests pulmonary embolism or myocardial ischemia, or both, as well as a platelet count of 54,000. [drsami.com]
Face, Head & Neck
- Malar Rash
rash Discoid rash With pregnancy there is an increased incidence of pre-eclampsia, uterine infection, SAb, prematurity, IUGR, congenital heart bloack and endomyocardial fibrosis. [pathologyexpert.com]
Urogenital
- Uremia
Seite 110 - Uremia refers to a toxic condition associated with renal insufficiency produced by the retention in the blood of nitrogenous substances normally excreted by the kidneys. [books.google.de]
Am J Cardiol 37: 1069 CrossRef PubMed CAS Google Scholar Cooper RA (1970) The pathogenesis of burr cells in uremia. [link.springer.com]
This erythropoietic effect has led to the therapeutic administration of 60 to 150 mg of cobalt chloride to patients with refractory anemias such as the anemias of chronic infection, cancer, or uremia.52 Consequently, in the treatment of anemias, an agent [medtextfree.wordpress.com]
Neurologic
- Neglect
Forbes Springer Science & Business Media, 6 Dec 2012 - Medical - 262 pages After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques [books.google.com]
Forbes Springer Science & Business Media, 06.12.2012 - 262 Seiten After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques, and [books.google.de]
- Irritability
Fallot) results from a failure to load oxygen onto hemoglobin adequately in the lungs.4,5 The hematocrit may range from 60% to 75% and cause profound symptoms of hyperviscosity, including headache, dizziness, visual disturbances, fatigue, paresthesias, irritability [what-when-how.com]
Workup
A workup revealed no evidence of polycythemia rubra vera or a secondary cause of his polycythemia (his erythropoietin level was normal, he had no splenomegaly, and a test for JAK2 v617F mutation was negative). [plexusmd.com]
However, it has never been shown that an exhaustive workup for malignancy is cost-effective or beneficial. [drsami.com]
A patient’s travel history should be taken to determine the likelihood of high-altitude effect and thus possibly avoid having to conduct an extensive workup. [what-when-how.com]
A workup revealed no evidence of polycythemia rubra vera or a secondary cause of her polycythemia (her erythropoietin level was normal, she had no splenomegaly, and a test for JAK2 v617F mutation was negative). [clinmedjournals.org]
Serum
- Burr Cell
Echinocytes are cells with many blunt spicules. They may be artefactual - see Crenated cells - or pathological - see Burr cells above. [patient.info]
Am J Cardiol 37: 1069 CrossRef PubMed CAS Google Scholar Cooper RA (1970) The pathogenesis of burr cells in uremia. [link.springer.com]
- Erythroblast
Erythroblasts (normoblasts) are immature, nucleated RBCs seen in the peripheral blood in leukoerythroblastic anaemia, haemolysis, hypoxia and marrow infiltration. Fragmented red cells - see Schistocytes below. [patient.info]
Treatment
Treatment Centers Edit Please add treatment centers available. Include contacts. Link any mentions you make to the online source if available. [wikicure.wikia.com]
The team concluded that treatment should involve strict hypertension control, avoidance of diuretic treatment, smoking cessation, and, in obese patients, the implementation of a strong weight reduction plan. [medicaldialogues.in]
Gaisbock Syndrome: A Review of Contemporary Studies, Pathogenesis, Complications, and Possible Treatment Nabeela Manal et al. Cardiol Rev. 2022. [pubmed.ncbi.nlm.nih.gov]
Treatment of Arrhythmias and Conduction Defects Indications for Treatment Electrophysiologic Drug Testing Results of Treatment Antiarrhythmic Agents High-Energy Capacitator Discharges Pacemaker Therapy Neuromechanical Maneuvers Atrioventricular Conduction [elsevier.com]
What Is the Treatment for Secondary Polycythemia? Treatment of secondary polycythemia depends on its cause. Supplemental oxygen can be provided for individuals with chronic hypoxia. [emedicinehealth.com]
Prognosis
Prognosis Prognosis is impaired by the development of cardiovascular complications. [orpha.net]
Pulmonary Embolism (PE) and Peripheral Venous Disease Clinical Aspects Diagnosis Prognosis Treatment II. Pulmonary Hypertension Classification Etiology Pathophysiology Symptoms Diagnosis Prognosis Therapy III. Pulmonary Vasculitides IV. [elsevier.com]
Differential Diagnosis Primary myelofibrosis Chronic myeloid leukemia Prognosis Studies estimate the median survival in cases diagnosed with polycythemia vera to be approximately 14.1 years.[11] Factors that were found to correlate with better prognosis [statpearls.com]
Prognosis Curing or removing the underlying cause of this disorder generally eliminates the symptoms. Resources OTHER "Secondary Erythrocytosis." The Merck Page. June 3, 1998. 〈 http://www.merck.com 〉. [encyclopedia.com]
Etiology
Etiology and Incidence II. [elsevier.com]
Excerpt Although the etiology of polycythemia vera remains unknown, repeated attempts have been made to correlate the condition with some cardiovascular phenomenon. [acpjournals.org]
Secondary etiologies for hypertension evaluating for renal artery stenosis, Coarctation of the aorta, hyperaldosteronism, and Pheochromocytoma were all unrevealing. [asn-online.org]
Abstract The frequency of renal diseases of different etiologies as discovered on kidney biopsy has been fairly consistent in series reported by various authors (1-10). [annals.org]
[…] sex-related normal ranges Erythrocytoses are further subclassified into primary, secondary, and relative erythrocytosis Primary and secondary erythrocytosis show true increase Relative erythrocytosis Hemoconcentration secondary to reduced plasma volume ETIOLOGY [basicmedicalkey.com]
Epidemiology
Summary Epidemiology It occurs mainly in male sedentary individuals, on a high-calorie diet. Prevalence is unknown. [orpha.net]
ORIGINAL PAPERS: Epidemiology results from the national inpatient sample database Krishnamoorthy, Parasurama; Gopalakrishnan, Akshayaa; Mittal, Varunb; Kalla, Aditia; Slipczuk, Leandroa; Rangaswami, Jananic; Figueredo, Vincent M.a; Messerli, Franz H.d [journals.lww.com]
Gaisbock Syndrome: A Rare Etiology of Secondary Hypertension Session Information Hypertension and CVD: Epidemiology, Risk Factors, Prevention November 03, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building Abstract Time: 10: [asn-online.org]
Epidemiology Epidemiological data refers to the US, unless otherwise specified. Pathophysiology The JAK2 (Janus kinase 2) oncogene codes for a non-receptor tyrosine kinase in hematopoietic progenitor cells. [www-amboss-com.db.rsu.lv]
Pathophysiology
Alveolar Hypoventilation and Sleep Apnea Syndrome Pathophysiology Clinical Aspects Treatment II. [elsevier.com]
Pathophysiology: Pituitary shut-down of FSH and LH production. Micro: Atrophic vaginal smear. [pathologyexpert.com]
A case report. ( 7661388 ) 1995 2 Stress polycythemia. ( 3837011 ) Mehta B.C. 1985 3 Stress polycythemia. ( 3997770 ) Nanavati N.J....Nihalani K. 1985 4 Stress polycythemia--a pathophysiologic study. ( 165576 ) El-Yousef M.K....Bakewell W.E. 1975 5 Stress [malacards.org]
However, no physiologic or pathologic basis has been found.In our study, which was designed to elicit the pathophysiology of this entity, two typical cases were studied. [jamanetwork.com]
Several mechanisms help explain the pathophysiology underlying Gaisbock's observations, and these include psychiatric disorders resulting in chronic stress, volume contraction secondary to diuretics and hypertension, and obstructive sleep apnea with nocturnal [pubmed.ncbi.nlm.nih.gov]
Prevention
Gaisbock Syndrome: A Rare Etiology of Secondary Hypertension Session Information Hypertension and CVD: Epidemiology, Risk Factors, Prevention November 03, 2022 | Location: Exhibit Hall, Orange County Convention Center‚ West Building Abstract Time: 10: [asn-online.org]
Fairly prevalent Early detection may prevent permanent impairment 1 To review: Learning Objectives Signs/symptoms Causes Management prevention treatment More information [ resident s case problem ] David G. [healthdocbox.com]
How Can I Prevent Polycythemia? Many causes of secondary polycythemia are not preventable. [emedicinehealth.com]
Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. [books.google.de]