Severe intellectual disability is often present. [rarediseases.org]

Our data thus expand the phenotypic spectrum of WDR4 mutations by demonstrating that, depending on the specific mutated allele, a renal phenotype may be present. [ncbi.nlm.nih.gov]

We reviewed their clinical manifestations, the prenatal and postnatal presentations and ultrasound findings, results of imaging studies, associated anomalies, and outcome on follow-up. [pesquisa.bvsalud.org]

• Anemia

  These findings, occurring in association with anemia and an abnormal accumulation of fluid that causes swelling (edema), may indicate a diagnosis of nephrotic syndrome. [rarediseases.org]

• Pneumonia

  […] inflammation of the esophagus (esophagitis); choking; closure of the larynx due to sudden, violent laryngeal contractions (laryngospasm); an inflammatory condition of the lungs caused by the entrance of food particles into the respiratory passages (aspiration pneumonia [rarediseases.org]

Clinical Testing and Workup In affected infants, symptoms associated with nephrotic syndrome may become apparent within days, weeks, months, or in some cases, years after birth. [rarediseases.org]

Treatment with corticosteroids and/or immunosuppressive drugs has not been effective for nephrotic syndrome associated with Galloway-Mowat syndrome. [rarediseases.org]

(July 2017) Treatment[edit] This section is empty. You can help by adding to it. (July 2017) References[edit] ^ a b Cooperstone BG, Friedman A, Kaplan BS (Aug 1993). [en.wikipedia.org]

61 Lin CC...Shih CS 11519896 2001 48 Diagnostic dilemmas in four infants with nephrotic syndrome, microcephaly and severe developmental delay. 61 de Vries BB...Winter RM 11310991 2001 49 A stepwise approach to the treatment of early onset nephrotic syndrome [malacards.org]

Parents should talk to the physician and medical team about their child’s specific case, associated symptoms and overall prognosis. [rarediseases.org]

Therapy with anti-seizure (anticonvulsant) drugs may be prescribed for affected individuals who experience seizures to help prevent, reduce, or control seizures. [rarediseases.org]