Presentation
A table comparing four commonly used products is presented. [ncbi.nlm.nih.gov]
The gamma globulin of the present invention when stored in the pharmaceutical compositions of the present invention has a longer half-life than the other gamma globulin preparations now on the market. [google.com]
Primary antibody deficiency syndromes most commonly present with recurrent infections due to encapsulated bacteria. [patient.info]
Hematological
- Hemophilia A
[…] of immunoglobulins immunoglobulin G one of the five major classes of immunoglobulins immunoglobulin M one of the five major classes of immunoglobulins antihemophilic globulin a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia [vocabulary.com]
The high content of anti-idiotypes against autoantibodies in IVIG facilitates its ability to neutralize autoantibodies, as is shown in patients with acquired hemophilia due to autoantibodies against factor VIII. [6] IVIG also has effects on the clearance [emedicine.medscape.com]
Entire Body System
- Fatigue
Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia (FM) and Small Fiber Neuropathy Studies Chronic Fatigue Syndrome (ME/CFS) Significant interest in gamma globulin resulted in several clinical trials in the 1990’s which had mixed results. [cortjohnson.org]
PURPOSE: Currently, there is no established therapy for chronic fatigue syndrome (CFS), a recently defined illness that has been associated with a variety of immunologic abnormalities. [ncbi.nlm.nih.gov]
A recent clinical trial of gamma globulin in chronic fatigue syndrome patients had no recognizable benefit, while an older trial showed improvement. [en.wikipedia.org]
Table 5: Adverse Events*, Regardless of Causality, that Occurred within 72 Hours of Infusion Event By Infusion By Subject Number Percentage Number Percentage Headache 57 6.90 22 36.1 Fever 19 2.30 13 21.3 Fatigue 18 2.18 10 16.4 Vomiting 10 1.21 9 14.8 [rxlist.com]
- Falling
MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. [mybiosource.com]
However, if the monoclonal protein falls within the beta region (most commonly an IgA or an IgM) quantitative immunoglobulin levels may be more a useful tool to follow the monoclonal protein level than PEL. [mayomedicallaboratories.com]
Although processors have been working at full capacity seven days a week, 24 hours a day to produce gamma globulin for 1953 and 1954, production will fall short of the total quantity needed in epidemic areas in 1953.There are only four processing laboratories [ccat.sas.upenn.edu]
- Intravenous Administration
The thrombocytopenia improved after the intravenous administration of gamma-globulin at a dose of 1 g/kg. Splenectomy was carried out. The results suggested that the usual dose of gamma-globulin is not always necessary. [ncbi.nlm.nih.gov]
intravenous administration of gamma globulins. [google.com]
A series of blood work, frequent visits to the health center for periodic check-ups, injections, and intravenous administrations of gamma globulin are very expensive. [medicalhealthtests.com]
Replacement of Intravenous Administration of Anti-D by Subcutaneous Administration in Patients with Autoimmune Thrombocytopenia. Pediatr Blood Cancer 2006; 47: 721-2. http://dx.doi.org/10.1002/pbc.21006. [professionaleducation.blood.ca]
Respiratoric
- Pertussis
Also, gamma globulin did not influence the patient's own immunologic response to pertussis. Gamma globulin therapy with high anti-pertussis toxin titers could be considered for treatment of severe pertussis. [ncbi.nlm.nih.gov]
[…] immunoglobulin levels, they are used in prophylaxis of viral infections, such as, for example, hepatitis, measles, German measles, chicken pox, mumps, yellow fever, rabies, herpes and smallpox; bacterial infections such as, for example, diphtheria, pertussis [google.com]
Gastrointestinal
- Overeating
There was a variable increase in kappa and lambda free light chains, a marker of gamma-globulin synthesis, over time with no significant difference between low and normal IgG groups. [ncbi.nlm.nih.gov]
Interestingly, over a median follow-up of 4 years, one-third of patients with normal baseline IgG developed a low IgG and this was unrelated to receiving chemotherapy (Figure 1). [bloodjournal.org]
- Nausea
Common side effects of Gammagard Liquid include flushing (warmth, redness, or tingly feeling), headache, dizziness, chills, muscle cramps, back or joint pain, minor chest pain, fever, nausea, vomiting, tiredness, or injection site reactions (pain, redness [rxlist.com]
Possible adverse reactions to saw palmetto include stomach pain, nausea, bowel changes, dizziness and headache. 40. [livestrong.com]
Anyone who shows the following signs of overdose should check with a physician immediately: unusual tiredness or weakness dizziness nausea vomiting fever chills tightness in the chest red face sweating KEY TERMS Hepatitis — Inflammation of the liver caused [encyclopedia.com]
Vasomotor symptoms include chills, fever, flushing, headache, nausea, rise in temperature, vomiting and malaise. [scielo.br]
Except for common infusion reactions (60%) such as headaches, flu-like symptoms, nausea and stiff neck which were addressed at the clinic by slowing infusion rates, hydrating patients, etc., side effects were low. [cortjohnson.org]
- Vomiting
Common side effects of Gammagard Liquid include flushing (warmth, redness, or tingly feeling), headache, dizziness, chills, muscle cramps, back or joint pain, minor chest pain, fever, nausea, vomiting, tiredness, or injection site reactions (pain, redness [rxlist.com]
Vasomotor symptoms include chills, fever, flushing, headache, nausea, rise in temperature, vomiting and malaise. [scielo.br]
Anyone who shows the following signs of overdose should check with a physician immediately: unusual tiredness or weakness dizziness nausea vomiting fever chills tightness in the chest red face sweating KEY TERMS Hepatitis — Inflammation of the liver caused [encyclopedia.com]
GI: nausea, vomiting. GU: oliguria, anuria, acute renal failure, acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis. Musculoskeletal: hip pain, joint pain, muscle stiffness (at injection site). [glowm.com]
These tests, called liver function tests, may be ordered if you are at risk for liver disease or have symptoms of liver disease, which may include: Jaundice, a condition that causes your skin and eyes to turn yellow Nausea and vomiting Itching Recurring [medlineplus.gov]
Liver, Gall & Pancreas
- Jaundice
These tests, called liver function tests, may be ordered if you are at risk for liver disease or have symptoms of liver disease, which may include: Jaundice, a condition that causes your skin and eyes to turn yellow Nausea and vomiting Itching Recurring [medlineplus.gov]
[…] breathing, coughing up blood; signs of a blood clot in your leg --pain, swelling, warmth, or redness in one or both legs; signs of a kidney problem --swelling, rapid weight gain, and little or no urinating; liver problems --fast heart rate, dark urine, jaundice [rxlist.com]
[…] disease Wilson’s disease Increased beta 1 or beta 2 globulins Biliary cirrhosis Carcinoma (sometimes) Cushing’s disease Diabetes mellitus (some cases) Hypothyroidism Iron deficiency anemia Malignant hypertension Nephrosis Polyarteritis nodosa Obstructive jaundice [aafp.org]
confusion, edema, severe headache, dizziness, passing out, abnormal heartbeat, bruising, bleeding, mood changes, joint pain, muscle pain, change in speech, vision changes, blurred vision, tremors, sweating a lot, severe abdominal pain, dark urine, jaundice [drugs.com]
Neurologic
- Confusion
I guess I am most confused with the gamma globulin being detected with the urine protein electrophoresis, while the serum protein electrophoresis shows no abnormalities. Thanks in advance. [myelomabeacon.org]
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances Electrophoresis is usually required to interpret an elevated immunoglobulin [mayomedicallaboratories.com]
Sometimes, however, the results of this examination can be confusing or difficult to interpret. [aafp.org]
[…] pain, redness, tenderness, warmth, or swelling in the arms or legs; change in color of an arm or leg; angina; shortness of breath; tachycardia; or coughing up blood), chills, skin discoloration, severe loss of strength and energy, seizures, bloating, confusion [drugs.com]
Treatment
A young homosexual man with immune thrombocytopenia recently had transient intravascular hemolysis during intravenous gamma globulin treatment. [ncbi.nlm.nih.gov]
Prognosis
The prognosis of Hopkins' syndrome is usually poor and the patients remain with permanent paralysis of the affected limb. [ncbi.nlm.nih.gov]
HIV infection in children is most often associated with symptomatic disease and poor prognosis. Treatment with antiviral therapy may be effective in changing the course of disease and decreasing mortality in this vulnerable population. [clinicaltrials.gov]
Prognosis Early diagnosis and appropriate immunoglobulin replacement therapy are essential. [patient.info]
Etiology
We encountered the case of a 4-year-old boy with thrombotic microangiopathy (TMA) of unknown etiology. [ncbi.nlm.nih.gov]
Future randomized studies that take into account the etiology of acute myocarditis will be required to determine the efficacy of IVGG. [bmccardiovascdisord.biomedcentral.com]
Epidemiology
Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow, Russia. [email protected] Abstract Interferon-alpha was detected in IFN pool produced by human leukocytes in the presence of gamma-globulin fraction proteins [ncbi.nlm.nih.gov]
The hepatitis studies were conducted under the sponsorship of the Commission on Viral Infections, Armed Forces Epidemiological Board, and were supported in part by the Office of the Surgeon General, Department of the Army. [nejm.org]
Pathophysiology
BACKGROUND: Research on the biological pathophysiology of autism has found some evidence that immune alterations may play a role in the pathophysiology of that illness. [ncbi.nlm.nih.gov]
Useful For Suggests clinical disorders or settings where the test may be helpful Detecting or monitoring of monoclonal gammopathies and immune deficiencies Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they [mayomedicallaboratories.com]
Moreover, there is a great need for further studies of the pathophysiology of acute myocarditis, which would allow for a better understanding of the etiology and the natural history of the disease. [bmccardiovascdisord.biomedcentral.com]
Prevention
This therapy is designed to prevent unexplained first trimester miscarriages. No previous cases of platelet autoimmunization associated with maternal immunization with paternal mononuclear cells has been reported. [ncbi.nlm.nih.gov]