Most manifest as seizures, though, based on location, they can present with focal neurological deficits. We present here a rare case of an infratentorial ganglioglioma presenting with hemorrhage. [ncbi.nlm.nih.gov]

• Fatigue

  He presented with headache, fatigue and occasional nausea and vomiting. MRI revealed three large, distinct tumours with striking cyst formation. Stereotactic craniotomy and excision of the temporal and occipital tumours confirmed ganglioglioma. [ncbi.nlm.nih.gov]

  We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019 [patientslikeme.com]

  Common symptoms may include: Headache(generally upon awakening in the morning) Vomiting Fatigue Seizures Weakness on one side of the body Diagnosis Physical and Neurological examination – the child may demonstrate evidence of increased pressure inside [drarunlnaik.com]

• Rhinorrhea

  After the surgery the patient recovered well except developing cerebrospinal fluid rhinorrhea, which was controlled by lumbar drainage. MRI 6 months later did not show any sign of progression. [ncbi.nlm.nih.gov]

• Nausea

  He presented with headache, fatigue and occasional nausea and vomiting. MRI revealed three large, distinct tumours with striking cyst formation. Stereotactic craniotomy and excision of the temporal and occipital tumours confirmed ganglioglioma. [ncbi.nlm.nih.gov]

  […] provide support and protection of neurons) Epidemiology of Ganglioglioma especially in children and young adults represent less than 2% of all primary brain tumours Symptoms of Ganglioglioma epileptic seizures signs of intracranial pressure (headache, nausea [hirntumorhilfe.org]

  Deling (2013) 15/M 1 year Headache, nausea, unsteady gait GTR + − No recurrence (19 months) 5. Deling (2013) 27/M 2 years Headache TR + − No recurrence (8 months) 6. [jstage.jst.go.jp]

  Case Report A 36–years–old female patient was admitted to the Neurosurgery Service due to an insidious picture of headache and dizziness that had started 18 months before, occasionally associated with nausea and vomiting. [austinpublishinggroup.com]

• Polydipsia

  CASE: A 7-year boy presented with polyuria, polydipsia, and progressive visual loss for 18 months. Investigations revealed diabetes insipidus. [ncbi.nlm.nih.gov]

• Macrocephaly

  Here we report on a 9-year-old girl who was diagnosed as having a clavicular arteriovenous malformation with limb enlargement, an axillary port wine stain and macrocephaly with frontal bossing. [ncbi.nlm.nih.gov]

  A 7-month-old male infant with macrocephaly, dilated scalp veins, mild sunsetting, and bulging fontanelles View Case [ajnr.org]

• Progressive Loss of Vision

  A 20-year-old man presented with a 3-month history of headache, vomiting, and progressive loss of vision. Examination revealed bilateral papilledema. [neurologyindia.com]

• Hyperhidrosis

  Intramedullary spinal cord lesions can be a cause of hyperhidrosis. The authors report a rare case of intramedullary thoracic spinal cord ganglioglioma presenting as hyperhidrosis. [ncbi.nlm.nih.gov]

  Intramedullary spinal cord ganglioglioma presenting as hyperhidrosis: unique symptoms and magnetic resonance imaging findings: case report. J Neurosurg Spine. 2013 Feb. 18(2):184-8. [Medline]. Zhang S, Ai L, Chen XZ, Wang K. [emedicine.medscape.com]

• Abnormal Sweating

  This 16-year-old boy presented with abnormal sweating on the right side of the neck, chest, and the right arm that had been occurring for 6 years. [ncbi.nlm.nih.gov]

• Polyuria

  CASE: A 7-year boy presented with polyuria, polydipsia, and progressive visual loss for 18 months. Investigations revealed diabetes insipidus. [ncbi.nlm.nih.gov]

• Headache

  A 61-year-old male presented with a 12-day history of headaches and general malaise. [ncbi.nlm.nih.gov]

  This is a case of an adolescent, who began having headaches, with warning signs related to an arteriovenous malformation hindering the diagnosis of this rare tumour. This presented in its aggressive, multi-focus form. [pure.urosario.edu.co]

• Neglect

  He had a left visual field hemianopia and left visual field neglect. Brain computer tomography and magnetic resonance imaging revealed a hemorrhagic tumor located in his right atrium. [ncbi.nlm.nih.gov]

• Focal Seizure

  Infratentorial GGs typically present with signs and symptoms of increased intracranial pressure (ICP), cranial nerve deficits, or focal cerebellar findings; rarely, these tumors have been associated with focal seizures. [ncbi.nlm.nih.gov]

• Dysphasia

  In this article, we presented a 53-year-old patient who presented with headache and dysphasia. The patient was operated for the cystic mass in the left parietal lobe reported as an abscess. [ncbi.nlm.nih.gov]

• Long Tract Signs

  Children with PF GG presented with ataxia, cranial nerve deficits and long tract signs whereas the majority with ST GGs presented with seizures. [ncbi.nlm.nih.gov]

Extensive workup for an inflammatory or infectious etiology was unfruitful and two brain biopsies were inconclusive. [ncbi.nlm.nih.gov]

• Hypsarrhythmia

  Interictal electroencephalography (EEG) showed diffuse bursts of slightly irregular high-voltage spikes and slow waves without hypsarrhythmia. [ncbi.nlm.nih.gov]

  Infantile spasms developed at age 6 months, an electroencephalogram revealing simultaneous hypsarrhythmia. [nature.com]

Treatment with Vemurafenib as single agent was started. For the first time, a radiological and clinical response was obtained after 3 months of treatment and sustained after 6 months. [ncbi.nlm.nih.gov]

Patients usually present with seizures refractory to medical treatment. Association with neurofibromatosis type I and tuberous sclerosis has been reported. [orpha.net]

Its prognosis and relationship with complicating hydrocephalus are unclear. [ncbi.nlm.nih.gov]

Desmoplastic medulloblastoma is more common in children younger than 3 years of age and has a better prognosis. 14 As in neuroblastoma, maturation of medulloblastoma cells may be associated with a better prognosis. 11 This case suggests that some types [pediatrics.aappublications.org]

[…] of Ganglioglioma favorable prognosis after complete surgical removal normal life expectancy can frequently be reached [hirntumorhilfe.org]

Extensive workup for an inflammatory or infectious etiology was unfruitful and two brain biopsies were inconclusive. [ncbi.nlm.nih.gov]

They may co-occur with adjacent focal cortical dysplasia (FCD IIIb), suggesting a common developmental etiology for both structural abnormalities. [epilepsydiagnosis.org]

The etiology of gangliogliomas is controversial as is their biological potential. Some lesions display neoplastic features including the potential to enlarge and behave in a malignant fashion. [path.upmc.edu]

He had macroscopic hematuria, for which etiologies other than nephrotoxicity secondary to the antineoplastic treatment were ruled out. [elsevier.es]

Through this case and literature review, the authors discuss some epidemiological, histological, clinical, radiological and management features of this very rare tumor. [ncbi.nlm.nih.gov]

Histology of Ganglioglioma mainly slowly growing tumour WHO grade I also WHO grad II and III can occur emerge from neoplastic ganglion cells (neural cells) and glia cells (provide support and protection of neurons) Epidemiology of Ganglioglioma especially [hirntumorhilfe.org]

Pediatric low-grade ganglioglioma: epidemiology, treatments, and outcome analysis on 348 children from the surveillance, epidemiology, and end results database. Neurosurgery. 2015 ;76: 313 – 319. Google Scholar | Crossref | Medline 6. [journals.sagepub.com]

Treatments, and Outcome Analysis on 348 Children From the Surveillance, Epidemiology, and End Results Database. ( 27428631 ) Arko L....Fierst T.M. 2016 [malacards.org]

The patient is scheduled for adjuvant radiotherapy with the hope of prevention of progression. [ncbi.nlm.nih.gov]

Therefore, currently, no guidelines or methods are available towards preventing tumor formation Active research is currently being performed to explore the possibilities for treatment and prevention of tumors such as Anaplastic Ganglioglioma Regular medical [dovemed.com]

Radiation therapy Radiation therapy uses X-rays to kill the cells and prevent them from growing. External radiation therapy, a type of radiation therapy uses machines outside the body to deliver the dose. [isitcurable.com]

Patients With Newly Diagnosed Pontine Glioma 3 NCT01188096 A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas 2 NCT03152318 A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 2 NCT03194906 Memantine for Prevention [virtualtrials.com]

The patient is scheduled for adjuvant radiotherapy with the hope of prevention of progression. © 2015 S. Karger AG, Basel References Courville CB: Ganglioglioma, tumor of the central nervous system: review of the literature and report of two cases. [karger.com]