Despite several therapeutic approaches have been successfully tested for preventing chronic bleeding, some patients present recurrence of GAVE lesions. [ncbi.nlm.nih.gov]

Image: Gastrolab/ kolumbus.fi S&S Most patients present with iron deficiency anemia as a result of chronic blood loss; rarely, GAVE may present as acute upper GI bleed. [uptodategastro.wordpress.com]

• Hunting

  Moreover, the hunt for molecular underpinnings of the broad array of vascular lesions in SSc has to include von Willebrand factor and endoglin. [ncbi.nlm.nih.gov]

  View Article PubMed Google Scholar Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, Sinclair P: International Consensus Upper Gastrointestinal Bleeding Conference Group. [bmcgastroenterol.biomedcentral.com]

• Renal Artery Stenosis

  Renal artery stenosis, aortic stenosis, widespread cutaneous and mucosal telangiectasia and hypertension seem to be associated with poor prognosis and should prompt rapid intervention and careful follow-up. [ncbi.nlm.nih.gov]

  Renal artery stenosis, aortic stenosis, widespread cutaneous and mucosal telangiectasia and hypertension seem to be associated with poor prognosis and should prompt rapid intervention and careful follow‐up. [doi.org]

• Orthostatic Hypotension

  hypotension, frequent hypoglycemia, and gastroparesis. [doi.org]

• Neglect

  Gastric antral vascular ectasia (GAVE) is an uncommon and often neglected cause of gastric hemorrhage. The treatments for GAVE include surgery, endoscopy and medical therapies. Here, we report an unusual case of GAVE. [ncbi.nlm.nih.gov]

Long-term corticosteroids and heat probe therapy have been reported as a safe options in older, medically unfit patients, while others have advocated endoscopic laser treatment. 16, 17 Our case shows once again that in the workup for differential diagnosis [doi.org]

• Colonic Ulcer

  Chung, Colonic ulceration as an unusual manifestation of vasculopathy in systemic sclerosis, Rheumatology, 50, 3, (626), (2011). Jill Johnson and Chris T. [doi.org]

The pre-treatment haemoglobin and transfusion requirements were compared with the post-treatment values. RESULTS: There was a sustained increase in mean haemoglobin levels post-treatment. [ncbi.nlm.nih.gov]

Renal artery stenosis, aortic stenosis, widespread cutaneous and mucosal telangiectasia and hypertension seem to be associated with poor prognosis and should prompt rapid intervention and careful follow-up. [ncbi.nlm.nih.gov]

Renal artery stenosis, aortic stenosis, widespread cutaneous and mucosal telangiectasia and hypertension seem to be associated with poor prognosis and should prompt rapid intervention and careful follow‐up. [doi.org]

Everybody is different so the prognosis for GAVE is difficult to predict. Some patients do quite well, without any recurring bleeds after their initial treatment protocol. [marcusgi.com]

Additional transfusions may be recommended if gastrointestinal bleeding can not be stopped or controlled. [2] Last updated: 8/2/2016 The long-term outlook ( prognosis ) for people with watermelon stomach varies. [rarediseases.info.nih.gov]

Gastric antral vascular ectasia (GAVE) is an angiodysplastic disorder of unclear etiology and rare cause of upper gastrointestinal bleeding. [ncbi.nlm.nih.gov]

Rare disease associations and unusual clinical findings should be kept in mind for cases with obscure etiologies. We describe a rare cause of chronic anemia with a unique association. [doi.org]

[…] and GAVE syndrome are male (75%) with a mean age of 65 years. 1,2 Associated medical conditions include heart, liver, and kidney diseases; diabetes; connective-tissue diseases; hypothyroidism; and status as a bone marrow transplant recipient. 1–4 The epidemiologic [doi.org]

Up to the present, there had been more data regarding of the epidemiology, pathology including the outcomes of variable treatment modalities for this condition. [jnsbm.org]

This is similar to the epidemiologic features in human susceptible to cirrhosis and connective-tissue diseases to a certain extent [12,13]. [file.scirp.org]

This paper gives an overview of studies examining clinical presentation and pathophysiology, and reviews the current evidence for invasive and non-invasive treatments. [ncbi.nlm.nih.gov]

Despite several therapeutic approaches have been successfully tested for preventing chronic bleeding, some patients present recurrence of GAVE lesions. [ncbi.nlm.nih.gov]

TIPS and beta-blockers are ineffective for the long-term prevention of recurrent bleeding from GAVE. [link.springer.com]

Building a case: Immunosuppressive therapy for GAVE Currently, immunosuppressive therapy has no defined role in prevention of acute bleeding episodes from GAVE. [consultqd.clevelandclinic.org]

Routine coagulation of visible vessels may prevent delayed bleeding after endoscopic submucosal dissection--an analysis of risk factors. Endoscopy. 2008; 40 :179-183. [doi.org]

In the case of vascular ectasia bleeding, the use of PPIs could prevent rebleeding after APC hemostasis and enhance procedure-induced ulcer healing. [bmcgastroenterol.biomedcentral.com]