Presentation
We present here a rare case of gastric leiomyosarcoma revealed by a massive hematemesis in a young woman. We present a case of primary gastric leiomyosarcoma in a 16-year-old woman who presented with massive hematemesis. [ncbi.nlm.nih.gov]
Few mitotic cells, (3/50hpf) areas of necrosis and hemorrhage were present. The findings were consistent with leiomyosarcoma [Figure - 1]. [saudijgastro.com]
Entire Body System
- Pain
Severe chest pain – Sometimes severe chest pain can develop that feels like a heart attack. [paleotraining.eu]
A 72-year-old male patient with sudden onset severe epigastric pain was rushed into emergency service. After examination, the patient underwent urgent operation with possible diagnosis of perforated gastric or duodenal ulcer. [ncbi.nlm.nih.gov]
- Weight Loss
During this evaluation the patient expressed a desire for weight loss; sleeve gastrectomy was determined to be the best option to achieve the patient’s goal of weight loss while still maintaining the oncologic principles. [sages.org]
Weight-loss surgeries may also improve GERD. often other gastrointestinal symptoms like symptoms are experienced when the stone lodges in acid reflux air bubble in chest premature for babies the Kidney failure; Obesity – indigestion may be due to Can [transnationalterrorism.eu]
The most common symptoms at the time of initial assessment were abdominal pain (51%), melena (36%), and weight loss (16%). Most often, the tumor was located in the greater curvature (25%), fundus (20%), or lesser curvature (16%) of the stomach. [ncbi.nlm.nih.gov]
This is a case report of a 13-year-old male Shar-pei dog with medical history of post prandial emetic episodes and progressive weight loss lasting eight months. [repositorio.unesp.br]
A 68-year old Saudi male was admitted with two months' history of anorexia, weight loss, intermittent fever, and sweats. Two weeks prior to admission, he had three episodes of hematemesis and melena accompanied by epigastric pain. [saudijgastro.com]
- Anemia
A 73 year-old female patient suffered from anemia and a palpable abdominal mass. Abdominal ultrasonography and magnetic resonance imaging revealed a lesion with papillary excrescences at the pancreatic tail. [ncbi.nlm.nih.gov]
There also may be mild anemia, weakness, gastrointestinal bleeding and vomiting of blood. [healthcentral.com]
[…] definition Small bowel leiomyosarcoma is a rare type of small bowel malignancy, originating in the smooth muscle cells within the muscularis propria or the muscularis mucosa, most often found in the jejunum, and presenting with gastrointestinal bleeding and anemia [orpha.net]
Articles Yeast (Malassezia) Dermatitis April 24, 2019 Medical Articles Feline Stomatitis April 23, 2019 Medical Articles Toe Fractures April 19, 2019 Medical Articles Cat Immune System and Cancer April 19, 2019 Medical Articles Immune-Mediated Hemolytic Anemia [bluepearlvet.com]
Familial High-Risk Assessment: Colorectal Prostate Cancer Early Detection NCCN GUIDELINES FOR SUPPORTIVE CARE Cancer-Associated Venous Thromboembolic Disease Hematopoietic Growth Factors NCCN Guidelines Management of Cancer- and Chemotherapy-Induced Anemia [nccn.org]
- Asymptomatic
At the age of 12, an asymptomatic mass, which proved to be a paraganglioma (carotid-body tumor), was excised from the left side of the neck. When 24 years of age, she had massive hematemesis. At gastrectomy, there were five leiomyosarcomas. .. [nejm.org]
An asymptomatic 40-year-old female was diagnosed with primary lung leiomyosarcoma (T3N0), adenocarcinoma (T1aN0), and inflammatory myofibroblastic tumor, which were surgically removed without further treatment. [ncbi.nlm.nih.gov]
[…] cancer and none with LMS [5] other report from a University hospital in Riyadh found 10 of 18 cases of smooth muscle tumors of the GIT that were located in the stomach and 5 of them were confirmed to be gastric LMS [6] Patients with this tumor may be asymptomatic [saudijgastro.com]
Up to 30-50% of patients with GISTs are asymptomatic (3,4) at the time of diagnosis, particularly those with small tumors. [scielo.isciii.es]
- Fatigue
Causes People suffering from Gastric Leiomyosarcoma Radiology Zantac chronic gastric acid reflux nasal obstruction are likely to suffer frequently from sore throat as do Gastric Leiomyosarcoma Radiology Zantac chronic What causes GERD (acid Chronic Fatigue [transnationalterrorism.eu]
CAR T-Cell-Related Toxicities Prevention and Treatment of Cancer-Related Infections Survivorship NCCN Guidelines Late Effects/Long-Term Psychosocial and Physical Problems Anthracycline-Induced Cardiac Toxicity Anxiety and Depression Cognitive Function Fatigue [nccn.org]
Triggers known to cause mouth ulcers and gingivitis include: stress fatigue food allergies hormonal changes poor oral hygiene and sudden. [volunteering-alliance.eu]
PLEASE could be what’s causing the acid reflux symptoms GERD is common post gallbladder surgery. adrenal How To Heal Adrenal Fatigue. acid eflux lying on left stomach indigestion synonym remedies home burping side TREATMENT Current recommendations try [paleotraining.eu]
General symptoms associated with cancer may occur including fatigue, fever, weight loss, a general feeling of ill health (malaise), and nausea and vomiting. Pain may occur in the affected area but is uncommon. [rarediseases.org]
Gastrointestinal
- Abdominal Pain
Abdominal pain and/or gastrointestinal bleeding associated with an intramural or exogastric mass were typical features of this disease. Only tumor size and histologic grade were statistically significant prognostic factors. [ncbi.nlm.nih.gov]
The most common symptoms at initial presentation are abdominal pain and gastrointestinal bleeding. [jaoa.org]
- Hematemesis
We present here a rare case of gastric leiomyosarcoma revealed by a massive hematemesis in a young woman. We present a case of primary gastric leiomyosarcoma in a 16-year-old woman who presented with massive hematemesis. [ncbi.nlm.nih.gov]
When 24 years of age, she had massive hematemesis. At gastrectomy, there were five leiomyosarcomas. .. [nejm.org]
Abstract A 43-year-old Asian woman who was initially seen because of hematemesis later had a gastric leiomyosarcoma cliagnosed. [jaoa.org]
- Vomiting
More Severe vomiting animations & videos Medications or substances causing Severe vomiting: The following drugs medications substances or toxins are some of the All Activity; Home ; RemedySpot.com Forums on Ayurveda Yoga Health and Natural Healing ; Health [paleotraining.eu]
The triad signs are sudden and severe epigastric pain, uncontrollable making of vomiting noises without actually vomiting, and the impossibility of passing a nasogastric tube through to the gut. [news-medical.net]
There also may be mild anemia, weakness, gastrointestinal bleeding and vomiting of blood. [healthcentral.com]
[…] malignancy, originating in the smooth muscle cells within the muscularis propria or the muscularis mucosa, most often found in the jejunum, and presenting with gastrointestinal bleeding and anemia and sometimes with other non-specific symptoms such as vomiting [orpha.net]
The tumors may cause bleeding in the gastrointestinal tract and cause black, tarry, foul-smelling stools (melena), or vomiting of blood (hematemesis) or abdominal discomforts). [rarediseases.org]
- Nausea
[…] ve talked about a and new position once it comes to saving your acid reflux fluttering in chest Heartburn With Sweating And Nausea except this time there is no way to entice Heartburn With Sweating And Nausea The relationship between gastroesophageal [paleotraining.eu]
[…] originating in the smooth muscle cells within the muscularis propria or the muscularis mucosa, most often found in the jejunum, and presenting with gastrointestinal bleeding and anemia and sometimes with other non-specific symptoms such as vomiting, nausea [orpha.net]
These patients often have abdominal bloating, constipation, and nausea that may or may not be accompanied by vomiting. SV is thought to be associated with neurological pathologies such as multiple sclerosis and Parkinson’s disease. [news-medical.net]
"I might have a small snack about an hour before going to bed, but many nights, I don't. nausea and.Eggs/egg whites. [volunteering-alliance.eu]
Symptoms The symptoms of stomach cancer are similar to the symptoms of a hiatal hernia or peptic ulcer, namely a vague pain aggravated by food, nausea, heartburn and indigestion. [healthcentral.com]
- Epigastric Pain
A 72-year-old male patient with sudden onset severe epigastric pain was rushed into emergency service. After examination, the patient underwent urgent operation with possible diagnosis of perforated gastric or duodenal ulcer. [ncbi.nlm.nih.gov]
Methods: 49 year old male, presented with epigastric pain of several months duration. Upper GI endoscopy showed an ulcerated mass in the Gastric Fundus within 3 – 4 cm of the Gastroesophageal Junction. Biopsy demonstrated gastric leiomyosarcoma. [sages.org]
The triad signs are sudden and severe epigastric pain, uncontrollable making of vomiting noises without actually vomiting, and the impossibility of passing a nasogastric tube through to the gut. [news-medical.net]
Two weeks prior to admission, he had three episodes of hematemesis and melena accompanied by epigastric pain. He developed swelling of the abdomen and lower limbs a few days later. Review of systems revealed no additional symptoms. [saudijgastro.com]
Liver, Gall & Pancreas
- Hepatomegaly
Some findings might be: Enlarged lymph nodes above the left collarbone (supraclavicular node) Nodal masses around the rectum, inside the navel or in the abdomen (involving the ovary) Enlarged liver (hepatomegaly) Increased fluid intake in the abdomen [healthcentral.com]
There were no abdominal wall varices, no hepatomegaly, and no palpable mass or adenopathy. Laboratory blood tests revealed a haemoglobin level at 38 g/l with haematocrit at 13.4%. The mean corpuscular volume was in the normal range. [bmcsurg.biomedcentral.com]
- Jaundice
There was no jaundice, cyanosis, peripheral lymphadenopathy or spider naevi. His temperature was normal and, there was pitting edema of the lower extremities. Apart from moderate ascites, abdominal examination was normal. [saudijgastro.com]
Skin
- Ulcer
Histologically, the tumors with ulceration showed more severe nuclear atypia (p < 0.05), necrosis (p < 0.01), and a higher incidence of mitosis (p < 0.01), compared with tumors without ulceration. [ncbi.nlm.nih.gov]
H. tric ulcer i White Fiorence How to Mr. [volunteering-alliance.eu]
Musculoskeletal
- Fracture
Enteropathy (Inflammatory Bowel Disease) View Article All Articles Medical Articles Cat Skin and Fur April 24, 2019 Medical Articles Yeast (Malassezia) Dermatitis April 24, 2019 Medical Articles Feline Stomatitis April 23, 2019 Medical Articles Toe Fractures [bluepearlvet.com]
[…] moderate grade tumor arising from smooth muscle origin IMPORTANCE Relatively rare, accounting for ~7% of all soft-tissue sarcomas CLINICAL FEATURES 9-80 years of age (mean = 52) M:F = 1-2.4:1 90% with pain averaging 11 months in duration (± pathologic fracture [orthopaedicsone.com]
Workup
Microbiology
- Helicobacter Pylori
الصفحة 71 - Hypothesis: the changing relationships of Helicobacter pylori and humans : implications for health and disease. J. Infect. Dis. [books.google.com]
0 218 Cited 0 times in Helicobacter pylori 양성인 위선암종의 p53 단백표현 Other Titles P53 immunoexpression in gastric adenocarcinoma with Helicobacter pylori infection Authors 장경희 Issue Date 1997 Description 의학과/석사 Abstract [한글] 위암의 발암 기전은 식생활, 위내 미세환경, 유전 등 다양한 [ir.ymlib.yonsei.ac.kr]
Gastroscopy
- Gastric Lesion
GLS occurs most frequently as a single lesion and rarely as multiple gastric lesions [3]. We report the occurrence of a multi-centric leiomyosarcoma in a Saudi male and the literature is reviewed briefly. [saudijgastro.com]
Colonoscopy
- Polyps
88963; 1% of all gastric cancers) Small Intestine Adenocarcinoma (81403) Lymphoma (many morphology codes) Leiomyosarcoma (88903, 88913, 88963) Carcinoids (82403, 82413, 82433, 82443) Synonyms for in situ carcinoma: (adeno)carcinoma in an adenomatous polyp [training.seer.cancer.gov]
[…] melanomas CD34 stains many spindled lesions but stains almost no carcinomas or melanomas DOG1 stains very few spindled lesions or melanomas or carcinomas Spindled, bland GIST DDx Leiomyoma Schwannoma Fibromatosis Sclerosing mesenteritis Inflammatory fibroid polyp [surgpathcriteria.stanford.edu]
Treatment
Therefore, wide local excision remains the preferred treatment when technically feasible. [ncbi.nlm.nih.gov]
Leiomyosarcoma Treatment Treatment depends on the stage of the disease, but may involve: Surgery Chemotherapy Radiotherapy Surgery is usually undertaken for curative treatment of your tumor, but can also be used in palliation if the cancer is causing [mystomachcancersymptoms.com]
There are many types of uterine sarcoma, and they vary in their prognosis and treatment. MSK pathologists are experts at diagnosis. Many treatments are available, depending on the type and stage of disease. [mskcc.org]
Prognosis
Among these factors, mucosal ulceration has been identified as a new factor associated with poor prognosis. [ncbi.nlm.nih.gov]
Etiology
Country of Publication: Argentina NLM ID: 0204271 Publication Model: Print Cited Medium: Internet ISSN: 1669-9106 (Electronic) Linking ISSN: 00257680 NLM ISO Abbreviation: Medicina (B Aires) MeSH Terms : Hyperaldosteronism/*diagnosis Hypertension/*etiology [opac.wsb.torun.pl]
The rarity of LMS is worldwide and the etiology of these tumors is unknown. Predisposing factors to its development are not well understood. Therefore, its prevention is a major challenge to researchers. 1. Remine WH. [saudijgastro.com]
Gastrointestinal stromal tumours in patients with other-type cancer: a mere coincidence or an etiological association? A study of 97 GIST cases. Z Gastroenterol. 2005 Sep;43(9):1025-30. [gistsupport.org]
Epidemiology
Cornwall JVDore CJLewis JD Leg ulcers: epidemiology and aetiology. [volunteering-alliance.eu]
Epidemiology United States statistics Intestinal leiomyosarcomas are fairly rare, with a frequency of around 1.4 cases per 100,000 patients. [emedicine.medscape.com]
^ "Surveillance, Epidemiology, and End Results (SEER) Program Stat Database: Incidence—SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2016 Sub 2000-2014 Katrina/Rita Population Adjustment—Linked To County Attributes - Total [en.wikipedia.org]
The rarity of these tumors has prevented the performance of large epidemiological studies to identify risk factors. Data regarding parity, onset of menarche, or age at menopause as risk factors are inconclusive. [sarcomahelp.org]
Pathophysiology
Pathophysiology, diagnosis, and treatment of gastrointestinal stromal tumors. J Gastroenterol. 2005;40:775-780. La información aquí suministrada complementa la atención recibida por su médico. [cancercarewny.com]
Pathophysiology The causes of leiomyosarcoma are unknown. These lesions apparently arise between the muscularis propria and muscularis mucosa layers of the bowel wall, though the exact histological source is in question. [emedicine.medscape.com]
Prevention
[…] and early detection of cervical cancer: American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. [nccn.org]
[…] of the stomach and esophagus (and cause cancer Natural Treatment for Acid Reflux #6 – Take a Hydrochloric Acid Supplement “Home Remedies for Acid Reflux” Do Make sure You Consume Lots of Himalayan Pink Rock Salt Symptoms Of Chronic Heartburn Diet To Prevent [paleotraining.eu]
Radiation therapy works to destroy cancer cells by depositing energy that damages their genetic material, preventing or slowing their growth and replication. [rarediseases.org]
The surgery aims to primarily reduce the degree of twisting and prevent any chances of recurrence while taking care of factors that create a predisposition. [news-medical.net]
Therefore, its prevention is a major challenge to researchers. 1. Remine WH. Gastric sarcomas Am J Surg 1970; 120: 320-3. 2. Colovic RB, Colovic M, Ciganovic D, Matic S. [saudijgastro.com]