Presentation
CONCLUSION: PGL is usually of NHL type, presenting in the sixth decade, and can be successfully treated with both surgery and chemotherapy when patients presented at stage II. [ncbi.nlm.nih.gov]
Entire Body System
- Weight Loss
Features of MyAccess include: Remote Access Favorites Save figures into PowerPoint Download tables as PDFs Go to My Dashboard Close • Epigastric pain and weight loss • Contrast radiographic or upper GI endoscopic evidence of gastric mass • Endoscopic [accesssurgery.mhmedical.com]
Symptoms mimicking gastritis-epigastric pain, hypochromic anemia, anorexia, and weight loss had been present for a few months before diagnosis. No Helicobacter pylori infection was shown at diagnosis. [ncbi.nlm.nih.gov]
- Inflammation
Gastric pseudolymphoma is generally considered a benign, reactive condition to chronic inflammation. We report a patient who, although initially diagnosed as having a gastric pseudolymphoma, was found to have a malignant gastric lymphoma 5 yr later. [ncbi.nlm.nih.gov]
[…] primary cancer in another organ -Associated with chronic Helicobacter pylori infection • Gastric pseudolymphoma -Consists of a mass of lymphoid tissue in the gastric wall often associated with an overlying mucosal ulcer -Represents response to chronic inflammation [accesssurgery.mhmedical.com]
With the eradication of this microorganism, chronic inflammation decreases and the density of submucosal lymphocytes dramatically declines 24. [doi.org]
MALT lymphoma most frequently arises within this type of lymphoid tissue after it has accumulated as part of a reaction to an infection or inflammation. Video Endoscopic Sequence 7 of 12. [gastrointestinalatlas.com]
- Pathologist
A pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis. [dovemed.com]
The pathologist evaluates the type of lymphoid cells that are present in the biopsy to establish the nature of the lesion. [encyclopedia.com]
In cases in which there were differences in the histologic interpretation between the original and reviewing pathologists, immunohistochemical studies were performed 18,19. [doi.org]
- Fever
The patient was a 59-year-old immunocompetent man who presented with intermittent fever of unknown origin and epigastric pain for 18 days. [ncbi.nlm.nih.gov]
The main symptoms of lymphoma include: Night Sweats Fever Abdominal Pain Indigestion Nausea and Vomiting Gastrointestinal Bleeding Weight Loss Diarrhea Anaemia Tiredness Breathlessness Pruritis or itchy skin Headaches Edema or fluid accumulation in the [mystomachcancersymptoms.com]
Clinical features : arises from bronchus-associated lymphoid tissue (BALT). 40% are asymptomatic and present with a solitary pulmonary nodule on CXR. [ 1 ] There may be cough, dyspnoea, haemoptysis, fever, weight loss. [patient.info]
A : No symptoms (The individual has not had weight loss, fever, or night sweats.) [medicinenet.com]
- Fatigue
Symptoms include epigastric pain, early satiety, fatigue and weight loss. [en.wikipedia.org]
Other general signs and symptoms, such as fatigue, weight loss, and appetite may also be seen Chemotherapy, surgery, radiation therapy, and other treatment measures may be used for treating Lymphoma of Stomach based on the assessment of the physician [dovemed.com]
Stomach cancer care at Mayo Clinic Symptoms Signs and symptoms of gastroesophageal junction cancer and stomach cancer may include: Fatigue Feeling bloated after eating Feeling full after eating small amounts of food Severe, persistent heartburn Severe [mayoclinic.org]
Gastroesophageal reflux disease occurs when the amount of gastric juice that refluxes into the see Heartburn and GERD Center A functional (frequent More severe symptoms include fatigue Acid Stomach Remedies By Mayo Clinic Trouble Breathing they're ANTI [mice-poland.eu]
In general, patients have stomach pain, ulcers, or other localized symptoms, but rarely do they suffer from systemic complaints such as fatigue or fever. [encyclopedia.com]
Gastrointestinal
- Abdominal Pain
She presented at our hospital with epigastric abdominal pain and upper gastrointestinal bleeding. Chemotherapy alone sufficiently controlled the disease and no additional therapeutic modalities were needed. [ncbi.nlm.nih.gov]
Biopsy of both areas revealed lymphoma of the non-Hodgkin's type. 54 year-old man with severe abdominal pain. Endoscopy revealed a 3 cm duodenal ulcer to account for his pain, along with this 1 cm violaceous raised lesion in the gastric antrum. [endoatlas.com]
- Vomiting
The diagnosis was suggested by feculent vomiting, and the fistula was located using barium enema and CT scan. Therapy consisted of local resection followed by combination chemotherapy. [ncbi.nlm.nih.gov]
[…] pseudolymphoma -Consists of a mass of lymphoid tissue in the gastric wall often associated with an overlying mucosal ulcer -Represents response to chronic inflammation and is not malignant • The principal symptoms are epigastric pain and weight loss • Nausea and vomiting [accesssurgery.mhmedical.com]
Patients with gastritis may present with epigastric pain, nausea, vomiting, or loss of appetite. [ctisus.com]
Gastric Lymphoma 52 year-old woman with chronic gastritis following a subtotal gastrectomy 14 years previously, presented with early satiety and vomiting. [endoatlas.com]
- Nausea
[…] pseudolymphoma -Consists of a mass of lymphoid tissue in the gastric wall often associated with an overlying mucosal ulcer -Represents response to chronic inflammation and is not malignant • The principal symptoms are epigastric pain and weight loss • Nausea [accesssurgery.mhmedical.com]
These include but are not limited to medications to counteract nausea and vomiting, intravenous fluids to treat dehydration, pain medications, antacids to lower the risk of ulcers, and bone marrow stimulating drugs to reverse the low white blood cell [rarediseases.org]
The main symptoms of lymphoma include: Night Sweats Fever Abdominal Pain Indigestion Nausea and Vomiting Gastrointestinal Bleeding Weight Loss Diarrhea Anaemia Tiredness Breathlessness Pruritis or itchy skin Headaches Edema or fluid accumulation in the [mystomachcancersymptoms.com]
- Epigastric Pain
Features of MyAccess include: Remote Access Favorites Save figures into PowerPoint Download tables as PDFs Go to My Dashboard Close • Epigastric pain and weight loss • Contrast radiographic or upper GI endoscopic evidence of gastric mass • Endoscopic [accesssurgery.mhmedical.com]
Symptoms mimicking gastritis-epigastric pain, hypochromic anemia, anorexia, and weight loss had been present for a few months before diagnosis. No Helicobacter pylori infection was shown at diagnosis. [ncbi.nlm.nih.gov]
- Intestinal Disease
Immunoproliferative small intestinal disease cases were seen in this study, which is uncommon in the west. [ijpmonline.org]
Varun Incidence and pathogenesis • Immunoproliferative small intestine disease special form of MALT lymphoma is suspected to have an infectious etiology • Celiac disease – risk factor for small bowel adenocarcinomas, esophageal cancer, melanoma and NHL [slideshare.net]
Small intestinal lymphomas that develop from immunoproliferative small intestinal disease have previously been linked to bacterial infection 32. [doi.org]
Immunoproliferative small intestinal disease (IPSID): a model for mature B-cell neoplasms. Blood. 2005; 105 :2274–2280. [ PubMed ] 45. [ncbi.nlm.nih.gov]
Psychiatrical
- Suggestibility
The case suggests that PGL is really a particular entity in the non-Hodgkin's lymphoma group, characterized by a long spontaneous natural history, with long lasting spontaneous remissions and recurrences. [ncbi.nlm.nih.gov]
A recent CT scan suggested gastric wall thickening, prompting a referral for endoscopy. Endoscopy revealed focal nodularity in the gastric cardia (left) and mucosal edema in the fundus (right). [endoatlas.com]
Workup
The incidence of this disease is increasing, making it necessary for clinicians to understand the clinical symptoms, workup, and treatment of these lymphomas. [ncbi.nlm.nih.gov]
The rest of his laboratory workup was unremarkable. [karger.com]
The Workup section above provides the most common ways that staging is done for MALT. [lymphomation.org]
Workup Routine hematological workup: Hemogram Biochemistry Staging workup UGIE Barium meal & follow through CT scan abdomen Endoscopic USG Chest X ray Bone marrow Optional Immunophenotyping LDH & ß 2 microglobulin CT scan features : Clefts & tracks in [slideshare.net]
Gastroscopy
- Gastric Lesion
US findings paralleled endoscopy during follow-up under antiblastic treatment: both improvement and lack of change in the gastric lesions were reliably predicted by US. [ncbi.nlm.nih.gov]
Treatment
Treatment of primary gastric diffuse large B-cell lymphoma is still controversial. The treatment of localized disease was based on surgery alone, or followed by chemotherapy and/or radiotherapy. [ncbi.nlm.nih.gov]
Prognosis
The clinical course and prognosis of this disease are dependent on histopathological subtype and stage at the time of diagnosis. [ncbi.nlm.nih.gov]
Etiology
There is now good evidence that infection with Helicobacter pylori (Hp) is etiologically important. [ncbi.nlm.nih.gov]
Conclusion In this patient, pancreatitis was the initial presentation of primary gastric lymphoma, which has notbeen commonly reported and therefore should be considered in the etiological workup. [pancreas.imedpub.com]
Disease Gastric adenocarcinoma Etiology Helicobacter pylori H. pylori is the single most important etiological agent in the pathogenesis of gastric cancer. [atlasgeneticsoncology.org]
[…] a proportion of cases The infiltrate is in the marginal zone of the reactive B-cell follicles and extends into the interfollicular region In epithelial tissues the neoplastic cells typically infiltrate the epithelium forming lymphoepithelial lesions Etiology [pathologyoutlines.com]
Epidemiology
Lymphoma, B-Cell, Marginal Zone/microbiology Lymphoma, B-Cell, Marginal Zone/pathology* Neoplasm Staging Pathology/methods* Pathology/standards Recurrence Remission Induction Stomach Neoplasms/drug therapy Stomach Neoplasms/epidemiology Stomach Neoplasms [ncbi.nlm.nih.gov]
Epidemiologic research: principles and quantitative methods. Belmont, Calif.: Lifetime Learning, 1982:159-80. 28. Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic research: principles and quantitative methods. [doi.org]
Pathophysiology
Hence, the aim of this study was to search proteins and/or protein complexes specific to Helicobacter pylori strains associated with gastric MALT lymphoma, in order to detect specific virulence factors and to better understand the cancer pathophysiology [theses.fr]
In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. Accessed March 23, 2016. Gastric cancer. [mayoclinic.org]
Sleisenger & Fordtran's gastrointestinal and liver disease: pathophysiology, diagnosis, management 8. Philadelphia: Saunders; 2006. p 567-85 Miljkovic' M,Senadhi V. Use of endoscopic ultrasound in diagnosing plasmacytoma of the pancreas. [pancreas.imedpub.com]
"Hepatic encephalopathy: pathophysiology and emerging therapies". Med. Clin. North Am. 93 (4): 819–36, vii. doi : 10.1016/j.mcna.2009.03.009. [en.wikipedia.org]
Prevention
Consequently, a global therapeutic approach to the cure of PG-NHL has completely changed over the last 10 years: innovative, conservative options to reduce treatment toxicity, thus preventing systemic relapses, have made their appearance and are on the [ncbi.nlm.nih.gov]
The lymph node function is to prevent infections from entering the bloodstream. When the lymphatic system is fighting an active infection, you may notice that some of the lymph nodes in the area of the infection become swollen and tender. [webmd.com]