Edit concept Question Editor Create issue ticket

Gastrointestinal Neoplasm


Presentation

  • CONCLUSION: The present questionnaire survey seems to reveal basic elements required for ESD training program. We believe that this is also helpful in other countries where ESD would be initiated and penetrated safely and properly. 2012 The Authors.[ncbi.nlm.nih.gov]
  • Presenting signs include diarrhea, rectal bleeding, intussusception, anemia, prolapse, and failure to thrive.[emedicine.medscape.com]
  • Very rare cases of SPM were observed in the present study.[journals.plos.org]
  • Coeliac disease is becoming increasingly recognized in patients presenting only isolated iron, folate or calcium deficiencies (1,2) and in asymptomatic relatives of coeliac patients (3), so called latent coeliac disease.[link.springer.com]
  • General features The clinical presentation of metastatic lung carcinoma to the common sites is well known.[touchoncology.com]
Weight Loss
  • Unexplained weight loss DNY59/Getty Images Many health conditions— including type 1 diabetes, Addison's disease, and Crohn's disease —can lead to unexplained weight loss. Add stomach cancer to that list, Dr. Sarpel says.[prevention.com]
  • Possible signs of small intestine cancer include Abdominal pain Weight loss for no reason Blood in the stool A lump in the abdomen Imaging tests that create pictures of the small intestine and the area around it can help diagnose intestinal cancer and[medlineplus.gov]
  • Some common symptoms of cancer that develops in the small intestines include: Abdominal pain Unexplained weight loss Weakness or fatigue (sometimes a result of anemia) Bloody or tarry stools (from bleeding tumors) A noticeable lump in the abdomen Small[cancercenter.com]
Anemia
  • Presenting signs include diarrhea, rectal bleeding, intussusception, anemia, prolapse, and failure to thrive.[emedicine.medscape.com]
  • A slowly bleeding tumor may lead to anemia. Digested blood may cause the stool to become black or tarry. An obstruction—when the flow of food is completely blocked—may cause intense pain, nausea and vomiting and typically requires immediate surgery.[cancercenter.com]
  • Pernicious anemia 12. h/o partial gastric resection 13.[slideshare.net]
  • GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass[orpha.net]
Fatigue
  • Symptoms such as abdominal pain, nausea, and fatigue overlap with many other conditions and diseases. If you’re experiencing any of these or other abnormal symptoms, you should talk with your doctor.[healthline.com]
  • Some common symptoms of cancer that develops in the small intestines include: Abdominal pain Unexplained weight loss Weakness or fatigue (sometimes a result of anemia) Bloody or tarry stools (from bleeding tumors) A noticeable lump in the abdomen Small[cancercenter.com]
  • One or more of the following symptoms may indicate carcinoid syndrome: facial flushing diarrhea abdominal pain (caused by blockage of the intestines) shortness of breath or wheezing fatigue rapid heartbeat weight gain or loss heart valve damage Patients[mskcc.org]
  • GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass[orpha.net]
Abdominal Pain
  • Peutz-Jeghers syndrome is diagnosed on the basis of family history, pigmented spots, and cramping abdominal pain.[emedicine.medscape.com]
  • However, some patients may experience symptoms such as facial flushing, diarrhea, abdominal pain, asthma, a rash, and dark-colored stools (which indicate intestinal bleeding).[mskcc.org]
  • This can also result in severe abdominal pain. Emergency surgery might be needed in these situations.[cancer.org]
  • Possible signs of small intestine cancer include Abdominal pain Weight loss for no reason Blood in the stool A lump in the abdomen Imaging tests that create pictures of the small intestine and the area around it can help diagnose intestinal cancer and[medlineplus.gov]
  • Some common symptoms of cancer that develops in the small intestines include: Abdominal pain Unexplained weight loss Weakness or fatigue (sometimes a result of anemia) Bloody or tarry stools (from bleeding tumors) A noticeable lump in the abdomen Small[cancercenter.com]
Loss of Appetite
  • GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass[orpha.net]
  • Nausea and vomiting Difficulty swallowing Heartburn Loss of appetite Weight loss Feeling tired Bloating Vomiting blood (in advanced stages) Cleveland Clinic News & More Cleveland Clinic News & More[my.clevelandclinic.org]
  • Other possible symptoms of GISTs Other symptoms of GISTs can include: Abdominal (belly) pain A mass or swelling in the abdomen Nausea, vomiting Feeling full after eating only a small amount of food Loss of appetite Weight loss Problems swallowing (for[cancer.org]
  • Symptoms may include: abdominal pain, tenderness, or discomfort change in bowel habits, such as frequency or consistency or shape rectal bleeding or blood in stool bloating loss of appetite nausea/vomiting unintentional weight loss fatigue These are common[verywellhealth.com]
  • Stomach cancer unexplained weight loss or loss of appetite difficulty swallowing indigestion – e.g. pain or burning sensation in the abdomen (heartburn), frequent burping, reflux persistent nausea and/or vomiting with no apparent cause a sense of fullness[cancervic.org.au]
Melena
  • […] mutation of c-kit 25% are clinically malignant Clinical features 2 - 3% of gastric malignancies Usually older adults, median age 60 - 65 years; 1% occur in children Male female incidence Symptoms: abdominal pain, gastric outlet obstruction, mass effect, melena[pathologyoutlines.com]
  • Massive hematemesis or melena is uncommon, but secondary anemia may follow occult blood loss. Occasionally, the first symptoms are caused by metastasis (eg, jaundice, ascites, fractures).[merckmanuals.com]
  • Eduardo Liceaga”, with 1-day history of melena (three episodes in 24 h), no nausea, no vomiting, no hematemesis, neither fever. His medical history was unremarkable and he has not recently used non-steroidal anti-inflammatory or steroid drugs.[elsevier.es]
  • The symptoms associated with gastrointestinal bleeding were defined as hematemesis, melena, and/or progression of anemia due to upper gastrointestinal lesions.[pancreas.imedpub.com]
  • A few may also occur within the abdomen and the retroperitoneum. 2,5 GI bleeding is the most common clinical presentation. 21 GI bleeding may be acute, presenting with hematemesis or melena, or may be chronic, presenting with anemia, weakness, and syncope[journals.lww.com]
Intestinal Disease
  • Stromal Tumors Intestinal Neoplasms Cecal Neoplasms Colorectal Neoplasms Duodenal Neoplasms Ileal Neoplasms Immunoproliferative Small Intestinal Disease Jejunal Neoplasms Stomach Neoplasms Zollinger-Ellison Syndrome[ncbi.nlm.nih.gov]
Failure to Thrive
  • Presenting signs include diarrhea, rectal bleeding, intussusception, anemia, prolapse, and failure to thrive.[emedicine.medscape.com]
Withdrawn
  • Gastrointestinal Neoplasms Colorectal Neoplasms Colorectal Cancer Esophageal Neoplasms Gastric Cancer Gastrointestinal Disease Any 17 and under 18 - 34 35 - 50 51 - 69 70 Available Active, not recruiting Not yet recruiting Recruiting Completed Terminated Suspended Withdrawn[patientwing-dev.vitaltrax.net]
  • Neoplasms Colorectal Neoplasms Intestinal Neoplasms Neoplasms Digestive System Diseases Gastrointestinal Neoplasms Any 17 and under 18 - 34 35 - 50 51 - 69 70 Available Active, not recruiting Not yet recruiting Recruiting Completed Terminated Suspended Withdrawn[patientwing.com]

Workup

  • […] and Staging Surgical Treatment Neoadjuvant Treatment Chemoradiation Chemotherapy for Palliation Summary and Further Reading Chapter 4 - Gastric Cancer Epidemiology and Clinical Presentation Diagnostic Workup, Staging and Surgery for Localised Disease[oncologypro.esmo.org]
  • The following tests are generally ordered in the workup of patients who present with nonspecific abdominal symptoms; abdominal pain; or complications such as hemorrhage, obstruction, or perforation: Complete blood cell count Coagulation profile Serum[emedicine.medscape.com]
  • Currently, there are no guidelines that recommend an initial endoscopic workup for evaluation of an underlying GI malignancy in dermatomyositis patients.[wjgnet.com]
  • CT scan is a very common study used in the USA for the workup of liver tumors. The ideal study is multi-phase CT scan with the use of oral and IV contrast. MRI can provide sectional views of the body in different planes.[patients.gi.org]
  • Incidental Detection of Neuroendocrine Carcinoma of Rectum During Staging Workup of Renal Cell Carcinoma. World J Oncol. 2015;6: 491–494. pmid:28983352 View Article PubMed/NCBI Google Scholar 86.[journals.plos.org]
Gastric Lesion
  • Figure 2 Gastric lesion in a man aged 73 years. (A) Endoscopic picture of a small area of redness (arrowheads) in the corpus amid atrophic gastric mucosa.[gut.bmj.com]
  • Watanabe H, Enjoji M, Yoo T, Ohsoto K: Gastric lesions in familial adenomatosis coli: Their incidence and histologic analysis. Hum Pathol 9:269–283, 1978 Google Scholar 10.[link.springer.com]
  • Endoscopic diagnosis of submucosal gastric lesions. The results after routine endoscopy. Surg Endosc. 1991;5:20–3. View Article PubMed Google Scholar Au WY, Ho KM, Shek TW.[wjso.biomedcentral.com]
  • For mucosal gastric lesions, endoscopy may be indicated. Concurrent imaging with CT and 18-fluorodeoxyglucose positron emission tomography (FDG-PET) may aid in the interpretation of CT findings, particularly where there is peritoneal disease.[journals.lww.com]
  • This radiographic study provides preliminary information that may help the physician determine if a gastric lesion is present and whether the lesion has benign or malignant features.[aafp.org]

Treatment

  • Treatment options include antacid therapy, as well as antireflux surgery or polypectomy.[emedicine.medscape.com]
  • Adjuvant Treatment Treatment of Unresectable Patients Palliative Treatment Second-Line Treatment Summary and Further Reading Chapter 8 - Hereditary Colorectal Cancer Syndromes Classification and Identification Non-Polyposis CRC Syndromes: Lynch Syndrome[oncologypro.esmo.org]
  • Our team is here to guide you through the stomach cancer treatment process and offer you hope for the future.[bswhealth.com]
  • The OSUCCC – James is one of the few high-volume peritoneal cancer treatment centers in Central Ohio.[cancer.osu.edu]
  • Esophagus and Stomach Cancer The treatment of stomach cancer often starts with chemotherapy followed by surgery. Esophageal cancer treatment may start with combined chemotherapy and radiation followed by surgery.[rmg.nm.org]

Prognosis

  • Prognosis is better with protruding tumors than with spreading tumors because protruding tumors become symptomatic earlier.[merckmanuals.com]
  • […] chondroma), familial GIST syndrome, Carney-Stratakis syndrome ( Am J Med Genet 2002;108:132 ) Sites: stomach (60%), jejunum and ileum (30%), duodenum (5%), colorectum (5%), rarely esophagus, appendix, retroperitoneum, abdomen (extra GI stromal tumors) Prognosis[pathologyoutlines.com]
  • Up to 50% of all GISTs will have evidence of metastatic disease at the time of presentation 3, which significantly impacts prognosis.[radiopaedia.org]
  • The book is divided into three main section - benign tumors, malignant tumors, and tumors with an indeterminate prognosis - reflecting the value of different imaging strategies as a function of a tumor's natural history.[books.google.ro]
  • Radiology in GI Tumours Technical Aspects Oesophageal Cancer Gastric Cancer Colon Cancer Rectal Cancer Pancreatic Cancer: Solid and Cystic Lesions Small Bowel Tumours Summary and Further Reading Chapter 3 - Oesophageal Cancer Epidemiology, Risk Factors, Prognosis[oncologypro.esmo.org]

Etiology

  • […] histology blood blood supply cerebrospinal fluid chemical synthesis chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology[ncbi.nlm.nih.gov]
  • Etiology of stomach cancer is multifactorial, but Helicobacter pylori plays a significant role. Symptoms include early satiety, obstruction, and bleeding but tend to occur late in the disease.[msdmanuals.com]
  • The Journal also offers basic and translational scientific information from studies providing insight into the etiology and progression of cancers affecting these organs.[link.springer.com]
  • The most common primary sites of upper GIT metastases leading to upper GIB include melanoma, lung, pancreas, breast and colorectal. 4,5 Endoscopy is frequently used to evaluate the etiology of an upper GIB and can often assist in making the diagnosis[cancertherapyadvisor.com]
  • Disease Gastric adenocarcinoma Etiology Helicobacter pylori H. pylori is the single most important etiological agent in the pathogenesis of gastric cancer.[atlasgeneticsoncology.org]

Epidemiology

  • […] analysis anatomy and histology blood blood supply cerebrospinal fluid chemical synthesis chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology[ncbi.nlm.nih.gov]
  • The second section covers essential developments exploring epidemiological factors implicated in GI cancer, disease prevention, the new opportunities that promise to advance our understanding, molecular subtyping, and tailored treatment of these diseases[oncologypro.esmo.org]
  • Abstract The epidemiology of coeliac disease is likely underestimated.[link.springer.com]
  • , Matthew Quinn, Sharon DeMorrow Review Article Interleukin-6 and its receptor, key players in hepatobiliary inflammation and cancer Christopher Johnson, Yuyan Han, Nathan Hughart, Jennifer McCarra, Gianfranco Alpini, Fanyin Meng Cholangiocarcinoma: Epidemiology[tgc.amegroups.com]
Sex distribution
Age distribution

Pathophysiology

  • Looking for Zebras in Metastatic Colorectal Cancer January 4, 2019 Although colorectal cancer is one of the most commonly diagnosed cancers in the United States,1 and researchers’ understanding of the biology and pathophysiology of CRC has grown, its[ruesch.georgetown.edu]
  • Outline the pathophysiologic development of colorectal cancer.[slideshare.net]
  • Consequently, GIST pathophysiology follows a common pathway with other mesenchymal neoplasms of the gastrointestinal tract and so, this may lead to obscure the diagnosis or to being confused with leiomyoma or leiomyosarcoma.[elsevier.es]
  • Pathophysiology [ edit ] GISTs are tumors of connective tissue, i.e. sarcomas ; unlike most gastrointestinal tumors, they are non epithelial. About 70% occur in the stomach, 20% in the small intestine and less than 10% in the esophagus.[en.wikipedia.org]
  • Pathophysiology Ooi et al identified three oncogenic pathways that are deregulated in the majority ( 70%) of gastric cancers: the proliferation/stem cell, NF-kappaβ, and Wnt/beta-catenin pathways.[emedicine.medscape.com]

Prevention

  • […] therapy economics embryology enzymology epidemiology ethnology etiology genetics history immunology legislation and jurisprudence metabolism microbiology mortality nursing organization and administration parasitology pathology physiology physiopathology prevention[ncbi.nlm.nih.gov]
  • At the OSUCCC – James, cancer research experts focus on studying stomach cancer prevention, diagnosis, treatment and cure.[cancer.osu.edu]
  • Colorectal Cancer Preventable. Treatable. Beatable. Each year nearly 137,000 people are diagnosed with colorectal cancer, often referred to as colon cancer, in the U.S. and over 50,000 people die from it annually.[asge.org]
  • […] for GI malignancies and advance new technologies into clinical trials to change practice in cancer prevention, control, and treatment across individual patients and the underserved.[kimmelcancercenter.org]
  • Since we know that tobacco is linked to some types of gastrointestinal cancer, avoiding both is one of our best prevention defenses. The health benefits of not smoking are numerous and are not limited to preventing gastrointestinal cancer.[verywellhealth.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!