Gastric sarcoidosis affects approximately 10% of patients with systemic disease and only rarely presents with symptoms. Here we present the case of a bleeding gastric ulcer in a 66-year-old female with pulmonary sarcoidosis. [elsevier.es]

A 68-year-old woman with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and dysphagia. [amjcaserep.com]

We present a 42-year-old white man with chronic diarrhea and abdominal pain for more than 3 years. Mucosal biopsies revealed non-caseating microgranulomas in the stomach, throughout the small intestine… CONTINUE READING [semanticscholar.org]

Diagnosis of sarcoidosis may be difficult, especially if no other typical features are present. [journals.lww.com]

Pediatric gastrointestinal sarcoidosis presenting with protein-losing enteropathy. [jhu.pure.elsevier.com]

• Splenomegaly

  Pulmonary nodules, pleural effusion, ascites, hepatomegaly, splenomegaly, and mesenteric as well as retroperitoneal and axillary lymphadenopathy were subsequently identified. [scielo.mec.pt]

  Sarcoidosis presenting as massive splenomegaly and bicytopenia. Am J Hematol. 2000; 63 :232-233. [ PubMed ] [ DOI ] 6. Thadani U, Aber CP, Taylor JJ. Massive splenomegaly, pancytopenia and haemolytic anaemia in sarcoidosis. [wjgnet.com]

  Liver and spleen usually, some enlargement of the liver (hepatomegaly) and spleen (splenomegaly) is seen and can be depicted with ultrasound, CT and MRI 1,3 ultrasound: pattern of either diffuse increased homogeneous or heterogeneous echogenicity nodules [radiopaedia.org]

• Weight Loss

  The first case was an 8-year-old Saudi girl who presented with fever, weight loss, and abdominal pain that was followed in a few months with hematemesis and development of hepatosplenomegaly. [ncbi.nlm.nih.gov]

  We present an interesting case of gastric sarcoidosis in a 39-year-old Caucasian man with symptoms of epigastric pain and profound weight loss. [hindawi.com]

  Despite compliance with treatment and proper dosing, the patient persisted to be febrile with further weight loss. [saudijgastro.com]

• Congestive Heart Failure

  Cardiac symptoms may include syncope (temporary loss of consciousness due to inadequate blood flow to the brain), congestive heart failure (CHF; the inability of the heart to adequately pump blood throughout the body causing a back up of fluid into the [healthcommunities.com]

  One patient is severely ill, with full congestive heart failure and sarcoidosis of the lung. She was dependent on steroids and had peripheral edema (probably partly due to the congestive heart failure and partly from the steroids). [ldnscience.org]

  Cardiologist : is a doctor who specializes in the diagnosis and treatment of heart disorders. Patients may see a cardiologist for cardiac (heart) sarcoidosis. Cardiologists can also treat heart attacks, hypertension and congestive heart failure. [stopsarcoidosis.org]

  Surgical options include placement of pacemakers or cardioverterdefibrillators, resection of affected areas of the heart, and cardiac transplantation. 3, 39 Pharmacologic therapy for treatment of congestive heart failure and arrhythmias should be used [aafp.org]

• Splenectomy

  He ultimately underwent a total gastrectomy, splenectomy and esophagojejunal anastomosis with J-tube, with another massive bleed after surgery. Watch to find out how physicians established the difficult diagnosis of systemic sarcoidosis. Dr. [consultqd.clevelandclinic.org]

  His past history included incidental diagnosis of sarcoidosis in spleen and gall bladder one year ago when he met with a motor vehicle accident and underwent elective cholecystectomy and splenectomy. [hindawi.com]

  One report describes thrombocytopenia and leukopenia secondary to hypersplenism a second report notes pancytopenia with splenomegaly both were resolved with splenectomy[ 5, 6 ]. [wjgnet.com]

  Splenomegaly and splenectomy in sarcoidosis. J Clin Pathol 1979; 32 :1050–1053. [nature.com]

  Secondary to a diagnosis of warm antibody hemolytic anaemia at the age of 47, treatment with steroids was initiated again with maximum doses of up to 150 mg prednisolone qd, which was extended to cyclophosphamide, mycophenolate, and finally splenectomy [bmcgastroenterol.biomedcentral.com]

• Hoarseness

  Neurologic manifestations include the following: Facial numbness and dysphagia Hoarseness Decreased gag reflex Headache Visual deficit Polydipsia Deafness Involvement of cranial nerves VII, VIII, IX, and X Basal granulomatous meningitis with involvement [emedicine.medscape.com]

• Vomiting

  A 68-year-old woman with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and dysphagia. [amjcaserep.com]

  The second case was a 9-year-old Sudanese boy who manifested with vomiting, epigastric pain, and weight loss. On upper endoscopy, both cases demonstrated severe erosive nodular gastric mucosa. [ncbi.nlm.nih.gov]

  Epigastric pain is the most common presenting symptom; however, nausea and vomiting may also occur in the presence of pyloric obstruction and the severity of nausea and vomiting depend on its degree of stenosis. [tandfonline.com]

  Discussion: Colonic sarcoidosis is a rare entity which commonly presents with abdominal pain, nausea/vomiting, hematochezia, diarrhea and weight loss. [journals.lww.com]

  Physical examination revealed an alert and oriented middle-aged woman in extremis who was vomiting dark-colored blood. [mdedge.com]

• Nausea

  A 68-year-old woman with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and dysphagia. [amjcaserep.com]

  Michele initially had lots of gastric and epigastric burning pain; also lots of nausea (associated w/ dizziness, cold sweats). the pain was resolved after i had a course of biaxin, nausea is controlled by large doses of neurontin. probably all depends [inspire.com]

  Epigastric pain is the most common presenting symptom; however, nausea and vomiting may also occur in the presence of pyloric obstruction and the severity of nausea and vomiting depend on its degree of stenosis. [tandfonline.com]

  None of them had diarrhea. 3 Our patient presented without epigastric pain but his presenting symptoms were nausea and diarrhea. [academic.oup.com]

  Discussion: Colonic sarcoidosis is a rare entity which commonly presents with abdominal pain, nausea/vomiting, hematochezia, diarrhea and weight loss. [journals.lww.com]

• Hematemesis

  The first case was an 8-year-old Saudi girl who presented with fever, weight loss, and abdominal pain that was followed in a few months with hematemesis and development of hepatosplenomegaly. [ncbi.nlm.nih.gov]

  We do not endorse non-Cleveland Clinic products or services Policy He was admitted to the medical intensive care unit with hematemesis and continued to rebleed despite multiple esophagogastroduodenoscopies and embolizations and ultimately required more [consultqd.clevelandclinic.org]

  A 47-year-old woman with a history of pulmonary and renal sarcoidosis presented for evaluation of hematemesis and melena. [mdedge.com]

• Rectal Mass

  Dis Colon Rectum 47:937–939 Article PubMed Google Scholar Zech JR, Kroger E, Bonnin AJ, Richmond GW (1993) Sarcoidosis: unusual cause of a rectal mass. [link.springer.com]

  Sarcoidosis: Unusual cause of a rectal mass. South Med J 1993; 86 :1054–1055. 41. Lieberman, J. Elevation of serum angiotensin-converting-enzyme (ACE) level in sarcoidosis. Am J Med 1975; 59 :365–372. 42. Ectors, NL, Dixon, MF, Geboes, KJ, et al. [nature.com]

  Zech JR, Kroger E, Bonnin AJ, Richmond GW (1993) Sarcoidosis: unusual cause of a rectal mass. South Med J 86: 1054-1055. [omicsonline.org]

• Intestinal Disease

  CD is a chronic inflammatory small intestinal disease with a prevalence of 1 % induced by gluten and related storage proteins of wheat, barley, and rye. [bmcgastroenterol.biomedcentral.com]

Given the multisystem involvement with significant chest findings, tissue findings of granulomatous disease, and negative workup for other causes of granulomatous inflammation, both cases were diagnosed with active disseminated sarcoidosis, and treated [ncbi.nlm.nih.gov]

Persistent diarrhea in patients with even remote history of chronic pulmonary signs and symptoms should prompt workup for gastrointestinal involvement by this granulomatous disease. © The American College of Gastroenterology 2017. [journals.lww.com]

Other laboratory workup to rule out the differential causes also came negative. With history of sarcoidosis, symptoms, and lab workup along with the histological findings the diagnosis was confirmed as gastric sarcoidosis. [hindawi.com]

Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. [books.google.es]

• Polyps

  Good luck GASTRIC POLYPS The prevalence of gastric polyps in the general population is approximately 0.8% to 2.4%.[209,210] Gastric polyps consist predominantly of fundic gland polyps (≈50%), hyperplastic polyps (≈40%), and adenomatous polyps (≈10%).[ [medhelp.org]

  Review the latest developments in the field and get up-to-date clinical information on hot topics like polyps, capsule endoscopy, and pancreatic treatments. [books.google.com]

  25.0) Basal cell hyperplasia 1 (20.0) 0 0 Tissue eosinophilia 2 (40.0) 0 0 Candida 1 (20.0) 0 0 Esophagitis, gastritis, duodenitis 1 (20.0) 10 (83.3) 1 (12.5) Ectopic gastric mucosa 1 (20.0) 0 0 Granuloma, Shaumann bodies, asteroid bodies 0 1 (8.3) 0 Polyp [giejournal.org]

  Endoscopy: Nodules (most common) Polyps Gastritis Thickened mucosa- can look like linitis plastica Benign or malignant-appearing ulcers Treatment: Steroids and monitor with serum ACE. PPIs can be ueful for related dyspepsia. [gastroenterologybook.com]

  Colonoscopy may show nodules, polyps, strictures, and erosions [15]. [karger.com]

Given the non-specific nature of symptoms, it is important to obtain histological evidence to make the diagnosis and guide treatment. The optimal treatment approach to GI sarcoidosis is not definitively known. [amjcaserep.com]

She received treatment with PPIs and H. pylori eradication therapy. Patient recovered well and her last endoscopy shows the lesion without ulceration (Figure 2). ???? Figure 1. [elsevier.es]

The patient's course was favorable after treatment with prednisone and chlorambucil. Disseminated gastrointestinal sarcoidosis may be a previously unidentified cause of protein-losing enteropathy. [ncbi.nlm.nih.gov]

Prior reports on cancer related sarcoidosis are inconsistent in terms of prognosis; while some reports link sarcoidosis with a favorable prognosis, others associate it with recurrence and secondary malignancies. [ascopubs.org]

The overall prognosis is good although most patients will have some permanent organ impairment. Cardiac and pulmonary diseases are the main causes of death. Find Full Text Links for this Article Related Papers [read.qxmd.com]

Prognosis and Patient Counseling. Generally, a good prognosis. Less than 5% of patients die of sarcoidosis, with neurosarcoidosis and cardiac sarcoidosis being the main causes of death. [cancertherapyadvisor.com]

TREATMENT AND PROGNOSIS The prognosis of sarcoidosis is good in most patients. The majority of patients with acute disease recover completely. Those patients who do have residual damage of affected organs usually have only minimal organ dysfunction. [meddean.luc.edu]

Seite 117 - Pulmonary sarcoidosis: role of CT in the evaluation of disease activity and functional impairment and in prognosis assessment. Radiology 191 (3): 675-680 141. ‎ [books.google.de]

A case-control etiologic study of sarcoidosis (ACCESS). Am J Respir Crit Care Med. 2001; 164(Suppl 11):2085-2091. Rybicki BA, Major M, Popovich J Jr., Maliarik MJ, Iannuzzi MC. [smartscitech.com]

The etiology of pneumatosis cystoides intestinalis in this case was likely multifactorial and involved both effects of the corticosteroids as well as the advanced nature of the gastrointestinal sarcoidosis. [ncbi.nlm.nih.gov]

These individuals are considered to have “granulomatous gastritis of uncertain etiology.” Some of these patients will eventually present with an identifiable etiology for the granulomatous gastritis. [peertechz.com]

ABSTRACT Sarcoidosis is a multisystemic granulomatous disease of unknown etiology that is based on the presence of non-caseating granulomas. Sarcoidosis commonly involves the lungs, skin, and eyes. [ekjm.org]

Sarcoidosis is a generalized granulomatous disease of unknown etiology that affects many tissues and is characterized pathologically by epithelioid tubercles with little or no necrosis. Over 90% of cases have pulmonary or mediastinal involvement. [annals.org]

and the Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit (B.A.R.). Address reprint requests to Dr. [nejm.org]

Introduction Definition a systemic inflammatory disease that is characterized by the presence of non-caseating granulomas Epidemiology incidence the lung is most commonly involved most common in African Americans Etiology unknown Pathogenesis macrophages [step2.medbullets.com]

Epidemiology of sarcoidosis: recent advances and future prospects. Semin Respir Crit Care Med 2007; 28:22-35. [PMID: 17330190] Rybicki B, Maliarik M, Major M, Popovich Jr J, Iannuzzi MC. Epidemiology, demographics, and genetics of sarcoidosis. [pancreas.imedpub.com]

References Mahadeva S, Goh KL: Epidemiology of functional dyspepsia: a global perspective. [cureus.com]

Unlike others on this topic, this text demonstrates how the endoscope incorporates pathophysiology, diagnostic, and treatment modalities into endoscopic practice. [books.google.es]

Analyses of gastrointestinal, oropharyngeal, lung and blood specimens will improve the understanding of H. pylori, VacA toxin, and other toxins as well as their potential role in pathophysiology of disease. [clinicaltrials.gov]

After I had thoroughly researched the mechanisms of action of LDN, I began prescribing it to patients who had inflammation as part of the pathophysiology of their conditions (Crohn's disease, ulcerative colitis, post-infectious IBS) and I saw good responses [ldnscience.org]

The differential diagnosis in particular with regard to refractory CD will be discussed based on a thorough clinical work-up, including genetic and immunological testing, that aimed to shed light on the pathophysiology of the disease association. [bmcgastroenterol.biomedcentral.com]

The exact mechanism of this relation is not known, but some evidence supports the hypothesis that this is a consequence of Th1 lymphokine prevalence. [55] [82] Tests of delayed cutaneous hypersensitivity have been used to measure progression. [83] Pathophysiology [en.wikipedia.org]

Early recognition and prompt treatment are important to prevent irreversible renal complications. Full Text [jamanetwork.com]

Special chapters, such as the Designing Clinical Research in Gastrointestinal Endoscopy, The Prevention of Infection Following Gastrointestinal Endoscopy, Complications of Peptic Ulcer Disease, and Credentialing for Gastrointestinal Endoscopy, help make [books.google.es]

NYU Langone doctors manage the condition, helping to prevent any long-term complications. Treatment at NYU Langone Treatment for sarcoidosis depends on the severity and duration of the disease. [nyulangone.org]

A 1, 5 Calcitonin (Miacalcin) and bisphosphonates may be useful in preventing osteoporosis in patients with sarcoidosis taking long-term steroid therapy. [aafp.org]