We present a 42-year-old white man with chronic diarrhea and abdominal pain for more than 3 years. Mucosal biopsies revealed non-caseating microgranulomas in the stomach, throughout the small intestine… CONTINUE READING [semanticscholar.org]

Diagnosis of sarcoidosis may be difficult, especially if no other typical features are present. [journals.lww.com]

Pediatric gastrointestinal sarcoidosis presenting with protein-losing enteropathy. [jhu.pure.elsevier.com]

A 4-year-old male patient with chronic diarrhea and abdominal distention for the last 8 months is presented. [turkarchpediatr.org]

Gastric sarcoidosis affects approximately 10% of patients with systemic disease and only rarely presents with symptoms. Here we present the case of a bleeding gastric ulcer in a 66-year-old female with pulmonary sarcoidosis. [elsevier.es]

• Weight Loss

  The first case was an 8-year-old Saudi girl who presented with fever, weight loss, and abdominal pain that was followed in a few months with hematemesis and development of hepatosplenomegaly. [ncbi.nlm.nih.gov]

  Despite compliance with treatment and proper dosing, the patient persisted to be febrile with further weight loss. [saudijgastro.com]

  We present an interesting case of gastric sarcoidosis in a 39-year-old Caucasian man with symptoms of epigastric pain and profound weight loss. [hindawi.com]

• Pleural Effusion

  Pulmonary nodules, pleural effusion, ascites, hepatomegaly, splenomegaly, and mesenteric as well as retroperitoneal and axillary lymphadenopathy were subsequently identified. [scielo.mec.pt]

  The computed tomography done on day seven of pain revealed bulky and heterogenous pancreas with peripancreatic stranding [Figure 1], with ascites and bilateral pleural effusion. [jdeonline.in]

  The family sought medical advice first in a local hospital where investigations revealed bilateral pneumonia, left-sided pleural effusion, and bilateral pulmonary nodules. There was a history of animal contact but no raw milk ingestion. [saudijgastro.com]

• Vomiting

  A 68-year-old woman with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and dysphagia. [amjcaserep.com]

  The second case was a 9-year-old Sudanese boy who manifested with vomiting, epigastric pain, and weight loss. On upper endoscopy, both cases demonstrated severe erosive nodular gastric mucosa. [ncbi.nlm.nih.gov]

  Epigastric pain is the most common presenting symptom; however, nausea and vomiting may also occur in the presence of pyloric obstruction and the severity of nausea and vomiting depend on its degree of stenosis. [tandfonline.com]

  Discussion: Colonic sarcoidosis is a rare entity which commonly presents with abdominal pain, nausea/vomiting, hematochezia, diarrhea and weight loss. [journals.lww.com]

  Physical examination revealed an alert and oriented middle-aged woman in extremis who was vomiting dark-colored blood. [mdedge.com]

• Nausea

  Michele initially had lots of gastric and epigastric burning pain; also lots of nausea (associated w/ dizziness, cold sweats). the pain was resolved after i had a course of biaxin, nausea is controlled by large doses of neurontin. probably all depends [inspire.com]

  A 68-year-old woman with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and dysphagia. [amjcaserep.com]

  Epigastric pain is the most common presenting symptom; however, nausea and vomiting may also occur in the presence of pyloric obstruction and the severity of nausea and vomiting depend on its degree of stenosis. [tandfonline.com]

  None of them had diarrhea. 3 Our patient presented without epigastric pain but his presenting symptoms were nausea and diarrhea. [academic.oup.com]

  Discussion: Colonic sarcoidosis is a rare entity which commonly presents with abdominal pain, nausea/vomiting, hematochezia, diarrhea and weight loss. [journals.lww.com]

• Hematemesis

  The first case was an 8-year-old Saudi girl who presented with fever, weight loss, and abdominal pain that was followed in a few months with hematemesis and development of hepatosplenomegaly. [ncbi.nlm.nih.gov]

  We do not endorse non-Cleveland Clinic products or services Policy He was admitted to the medical intensive care unit with hematemesis and continued to rebleed despite multiple esophagogastroduodenoscopies and embolizations and ultimately required more [consultqd.clevelandclinic.org]

  A 47-year-old woman with a history of pulmonary and renal sarcoidosis presented for evaluation of hematemesis and melena. [mdedge.com]

• Epigastric Pain

  A 68-year-old woman with pulmonary sarcoidosis presented with epigastric pain, nausea, vomiting, and dysphagia. [amjcaserep.com]

  The second case was a 9-year-old Sudanese boy who manifested with vomiting, epigastric pain, and weight loss. On upper endoscopy, both cases demonstrated severe erosive nodular gastric mucosa. [ncbi.nlm.nih.gov]

  Case presentation A 31-year-old female presented in the emergency room with intermittent epigastric pain for two weeks. [tandfonline.com]

  But he suggested nortryptiline or amytriptiline for the epigastric pain. I've been on 10 mg. of nortryptiline for over a month and have seen a vast difference. I no longer have the burning epigastric pain every day or wake up with it at night. [inspire.com]

• Chronic Diarrhea

  We present a 42-year-old white man with chronic diarrhea and abdominal pain for more than 3 years. Mucosal biopsies revealed non-caseating microgranulomas in the stomach, throughout the small intestine… CONTINUE READING [semanticscholar.org]

  A 4-year-old male patient with chronic diarrhea and abdominal distention for the last 8 months is presented. [turkarchpediatr.org]

  Case: We describe the case of a 55-year-old female with no significant past medical history who presented with chronic diarrhea. [journals.lww.com]

  We present a 42-year-old white man with chronic diarrhea and abdominal pain for more than 3 years. Mucosal biopsies revealed non-caseating microgranulomas in the stomach, throughout the small intestine, colon, and rectum. [acgcasereports.gi.org]

• Hepatosplenomegaly

  Computed tomography revealed massive hepatosplenomegaly and emphysematous lung changes. Liver biopsy showed non caseating granulomas. The patient was diagnosed with extrapulmonary sarcoidosis and was treated with prednisone. [ncbi.nlm.nih.gov]

  Physical examination revealed a pale girl, at 10 th percentile for weight and height, and hepatosplenomegaly. [saudijgastro.com]

  CT scans show hepatosplenomegaly and adenopathy, followed in frequency by focal low-attenuation lesions of the liver and spleen. [read.qxmd.com]

• Suggestibility

  These findings suggest that in patients with sarcoidosis, there is an altered gastrointestinal mucosal immune response, accompanied in about 40% of patients by specific sensitisation to wheat protein. [tara.tcd.ie]

  It was negative for mycobacterium tuberculosis and non-tuberculous mycobacterium, and showed multiple wellformed, nodular non-necrotizing granulomas, further suggesting a diagnosis of sarcoidosis ( Fig. 3 ). [synapse.koreamed.org]

  Also suggested a higher fiber diet. I have been doing this for about two weeks and it is improving. I would suggest finding a good Gastro Doc and have them check it out. Granulomas from Sarcoidosis can definately cause belly problems. [inspire.com]

Given the multisystem involvement with significant chest findings, tissue findings of granulomatous disease, and negative workup for other causes of granulomatous inflammation, both cases were diagnosed with active disseminated sarcoidosis, and treated [ncbi.nlm.nih.gov]

Persistent diarrhea in patients with even remote history of chronic pulmonary signs and symptoms should prompt workup for gastrointestinal involvement by this granulomatous disease. © The American College of Gastroenterology 2017. [journals.lww.com]

Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. [books.google.es]

Other laboratory workup to rule out the differential causes also came negative. With history of sarcoidosis, symptoms, and lab workup along with the histological findings the diagnosis was confirmed as gastric sarcoidosis. [hindawi.com]

• Left Pleural Effusion

  A body CT scan showed multiple peripheral and bilateral pulmonary nodules (Fig. 1), moderate left pleural effusion, bilateral axillary lymphadenopathy, slight homogeneous hepatosplenomegaly, multiple adenopathies in gastrohepatic ligament, and aortic [karger.com]

• Macrocytosis

  Throughout the 4-year follow up, the course of the disease was punctuated by several relapses on tapering of corticosteroids and later development of vitamin B 12 deficiency anemia: hemoglobin 10.6 gm/dL, macrocytosis (MCV 102, normal 80-91 fL), hyperchromasia [saudijgastro.com]

• Pleural Effusion

  Pulmonary nodules, pleural effusion, ascites, hepatomegaly, splenomegaly, and mesenteric as well as retroperitoneal and axillary lymphadenopathy were subsequently identified. [scielo.mec.pt]

  The computed tomography done on day seven of pain revealed bulky and heterogenous pancreas with peripancreatic stranding [Figure 1], with ascites and bilateral pleural effusion. [jdeonline.in]

  The family sought medical advice first in a local hospital where investigations revealed bilateral pneumonia, left-sided pleural effusion, and bilateral pulmonary nodules. There was a history of animal contact but no raw milk ingestion. [saudijgastro.com]

Given the non-specific nature of symptoms, it is important to obtain histological evidence to make the diagnosis and guide treatment. The optimal treatment approach to GI sarcoidosis is not definitively known. [amjcaserep.com]

The patient's course was favorable after treatment with prednisone and chlorambucil. Disseminated gastrointestinal sarcoidosis may be a previously unidentified cause of protein-losing enteropathy. [ncbi.nlm.nih.gov]

Incorporate the latest findings and improvements in care for liver disease patients —from diagnosis and treatment through post-treatment strategies and management of complications. Expert Consult eBook version included with purchase. [books.google.es]

Prior reports on cancer related sarcoidosis are inconsistent in terms of prognosis; while some reports link sarcoidosis with a favorable prognosis, others associate it with recurrence and secondary malignancies. [ascopubs.org]

The overall prognosis is good although most patients will have some permanent organ impairment. Cardiac and pulmonary diseases are the main causes of death. Find Full Text Links for this Article Related Papers [read.qxmd.com]

Prognosis and Patient Counseling. Generally, a good prognosis. Less than 5% of patients die of sarcoidosis, with neurosarcoidosis and cardiac sarcoidosis being the main causes of death. [cancertherapyadvisor.com]

TREATMENT AND PROGNOSIS The prognosis of sarcoidosis is good in most patients. The majority of patients with acute disease recover completely. Those patients who do have residual damage of affected organs usually have only minimal organ dysfunction. [meddean.luc.edu]

Seite 117 - Pulmonary sarcoidosis: role of CT in the evaluation of disease activity and functional impairment and in prognosis assessment. Radiology 191 (3): 675-680 141. ‎ [books.google.de]

A case-control etiologic study of sarcoidosis (ACCESS). Am J Respir Crit Care Med. 2001; 164(Suppl 11):2085-2091. Rybicki BA, Major M, Popovich J Jr., Maliarik MJ, Iannuzzi MC. [smartscitech.com]

The etiology of pneumatosis cystoides intestinalis in this case was likely multifactorial and involved both effects of the corticosteroids as well as the advanced nature of the gastrointestinal sarcoidosis. [ncbi.nlm.nih.gov]

These individuals are considered to have “granulomatous gastritis of uncertain etiology.” Some of these patients will eventually present with an identifiable etiology for the granulomatous gastritis. [peertechz.com]

ABSTRACT Sarcoidosis is a multisystemic granulomatous disease of unknown etiology that is based on the presence of non-caseating granulomas. Sarcoidosis commonly involves the lungs, skin, and eyes. [ekjm.org]

Sarcoidosis is a generalized granulomatous disease of unknown etiology that affects many tissues and is characterized pathologically by epithelioid tubercles with little or no necrosis. Over 90% of cases have pulmonary or mediastinal involvement. [annals.org]

and the Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit (B.A.R.). Address reprint requests to Dr. [nejm.org]

Introduction Definition a systemic inflammatory disease that is characterized by the presence of non-caseating granulomas Epidemiology incidence the lung is most commonly involved most common in African Americans Etiology unknown Pathogenesis macrophages [step2.medbullets.com]

Epidemiology of sarcoidosis: recent advances and future prospects. Semin Respir Crit Care Med 2007; 28:22-35. [PMID: 17330190] Rybicki B, Maliarik M, Major M, Popovich Jr J, Iannuzzi MC. Epidemiology, demographics, and genetics of sarcoidosis. [pancreas.imedpub.com]

In light of the strong epidemiological exposure, antituberculous medications were initiated (combination of isoniazid, pyrazinamide, ethambutol, and refampicin). [saudijgastro.com]

Unlike others on this topic, this text demonstrates how the endoscope incorporates pathophysiology, diagnostic, and treatment modalities into endoscopic practice. [books.google.es]

Analyses of gastrointestinal, oropharyngeal, lung and blood specimens will improve the understanding of H. pylori, VacA toxin, and other toxins as well as their potential role in pathophysiology of disease. [clinicaltrials.gov]

After I had thoroughly researched the mechanisms of action of LDN, I began prescribing it to patients who had inflammation as part of the pathophysiology of their conditions (Crohn's disease, ulcerative colitis, post-infectious IBS) and I saw good responses [ldnscience.org]

The differential diagnosis in particular with regard to refractory CD will be discussed based on a thorough clinical work-up, including genetic and immunological testing, that aimed to shed light on the pathophysiology of the disease association. [bmcgastroenterol.biomedcentral.com]

The exact mechanism of this relation is not known, but some evidence supports the hypothesis that this is a consequence of Th1 lymphokine prevalence. [55] [82] Tests of delayed cutaneous hypersensitivity have been used to measure progression. [83] Pathophysiology [en.wikipedia.org]

Early recognition and prompt treatment are important to prevent irreversible renal complications. Full Text [jamanetwork.com]

Special chapters, such as the Designing Clinical Research in Gastrointestinal Endoscopy, The Prevention of Infection Following Gastrointestinal Endoscopy, Complications of Peptic Ulcer Disease, and Credentialing for Gastrointestinal Endoscopy, help make [books.google.es]

NYU Langone doctors manage the condition, helping to prevent any long-term complications. Treatment at NYU Langone Treatment for sarcoidosis depends on the severity and duration of the disease. [nyulangone.org]

A 1, 5 Calcitonin (Miacalcin) and bisphosphonates may be useful in preventing osteoporosis in patients with sarcoidosis taking long-term steroid therapy. [aafp.org]