Sudhansu Chokroverty—a world-recognized expert in sleep medicine—presents the third edition of Sleep Disorders Medicine for the latest developments in this rapidly expanding specialty, with coverage of neuroscience and clinical application. [books.google.com]

We report on three such patients who presented as Coomb's positive haemolytic anaemia, systemic symptoms with agranulocytosis and gingival bleeding due to immune thrombocytopenia, to alert clinicians to the fact that primary Sjögren's syndrome may present [academic.oup.com]

[…] sleep, usually from a bed partner if present. [tipsdiscover.com]

• Skin Patch

  Signs and Symptoms Abnormality of the testis EMG abnormality Hemiplegia / hemiparesis Hyperreflexia Impaired pain sensation Incoordination Sensorineural hearing impairment Short stature Skeletal muscle atrophy Cognitive impairment Hypopigmented skin patches [familydiagnosis.com]

  patches Patchy loss of skin color 0001053 Hypoplasia of penis Underdeveloped penis 0008736 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Showing of 13 | Last updated: [rarediseases.info.nih.gov]

• Hypopigmented Skin

  Signs and Symptoms Abnormality of the testis EMG abnormality Hemiplegia / hemiparesis Hyperreflexia Impaired pain sensation Incoordination Sensorineural hearing impairment Short stature Skeletal muscle atrophy Cognitive impairment Hypopigmented skin patches [familydiagnosis.com]

  skin patches Patchy loss of skin color 0001053 Hypoplasia of penis Underdeveloped penis 0008736 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Showing of 13 | Last updated [rarediseases.info.nih.gov]

• Hearing Impairment

  Signs and Symptoms Abnormality of the testis EMG abnormality Hemiplegia / hemiparesis Hyperreflexia Impaired pain sensation Incoordination Sensorineural hearing impairment Short stature Skeletal muscle atrophy Cognitive impairment Hypopigmented skin patches [familydiagnosis.com]

  […] pain sensation Decreased pain sensation 0007328 Sensorineural hearing impairment 0000407 Short stature Decreased body height Small stature [ more ] 0004322 Skeletal muscle atrophy Muscle degeneration Muscle wasting [ more ] 0003202 30%-79% of people [rarediseases.info.nih.gov]

  Hearing is commonly impaired in BD and rates vary between 24 and 62%. [ejo.eg.net]

• Hyperreflexia

  Signs and Symptoms Abnormality of the testis EMG abnormality Hemiplegia / hemiparesis Hyperreflexia Impaired pain sensation Incoordination Sensorineural hearing impairment Short stature Skeletal muscle atrophy Cognitive impairment Hypopigmented skin patches [familydiagnosis.com]

  […] symptoms Abnormality of the testis 0000035 Ataxia 0001251 Delayed puberty Delayed pubertal development Delayed pubertal growth Pubertal delay [ more ] 0000823 EMG abnormality 0003457 Hemiplegia/hemiparesis Paralysis or weakness of one side of body 0004374 Hyperreflexia [rarediseases.info.nih.gov]

They concluded that skin biopsy played a valuable role in the workup of these patients. References 1. Gemignani F. Fibromyalgia syndrome and small-fiber neuropathy. Ann Neurol. 2014;76(6):916. [ PubMed ] 2. [therapath.com]

[…] sensations, exacerbation of this urge with rest, relief with activity, and worsening of symptoms toward evening. 1, 2 Though it is in most cases idiopathic, secondary forms associated with other diseases are known and must be considered in the clinical workup [jcsm.aasm.org]

The goal of the workup for SS is to eliminate differential diagnostic possibilities and to document the key features of SS ( Table 3 ). [jamanetwork.com]

The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]

Recently introduced prolonged-release oxycodone–naloxone was efficacious for short-term treatment of patients with severe RLS inadequately controlled with previous treatment. [dovepress.com]

Prognosis - Gemignani syndrome Not supplied. Treatment - Gemignani syndrome Not supplied. Resources - Gemignani syndrome Not supplied. [checkorphan.org]

This may improve dysphagia and pain. [1] If not, the web can be dilated during upper endoscopy to allow normal swallowing and passage of food. [4] Prognosis Patients generally respond well to treatment. [checkrare.com]

The risk of renal failure appears to be greater in those with HCV-associated disease. [22] The prognosis of renal disease in the more common type II cryoglobulinemia varies. [emedicine.medscape.com]

Endometrioid adenocarcinomas are very often non-invasive or superficially invasive and show a favorable prognosis (Navani et al., 1996). [atlasgeneticsoncology.org]

Articular manifestations in primary Sjögren’s syndrome: clinical significance and prognosis of 188 patients Rheumatology (Oxford) 2010 ; 49 : 1164-1172 [cross-ref] [31] Ramos-Casals M., Brito-Zeron P., Perez-De-Lis M., and al. [em-consulte.com]

The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]

Peripheral neuropathy may be considered an umbrella term that covers many forms of paresthesias of different etiology. [frontiersin.org]

Restless legs syndrome: Clinico-etiologic correlates. Neurology 1996;47:1435-1441. 6. Rutkove SB, Matheson JK, Logigian EL. Restless legs syndrome in patients with polyneuropathy. Muscle Nerve 1996;19:670-672. 7. Gemignani F, et al. [tipsdiscover.com]

Statement of Need and Purpose Restless legs syndrome (RLS) is a common neurologic disorder of unknown etiology that causes significant distress. [cmeinstitute.com]

Chapters on epidemiology, embryology, non-syndromic hearing loss, and syndromic forms of hearing loss have all been updated with particular attention to the vast amount of new information on molecular mechanisms, and chapters on clinical and molecular [books.google.com]

American Journal of Nephrology, 40(6): 499-506 [ CR ] [ EČ ][ GS ] Asper, R. (1984) Epidemiology and socioeconomic aspects of urolithiasis. [scindeks.ceon.rs]

Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institute of Health. Sleep Med. 2003;4(2):101-19. [ Links ] 5. [scielo.br]

Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology: a report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. [jcsm.aasm.org]

While exact data about the epidemiology is unknown, this syndrome has become extremely rare. [checkrare.com]

The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]

Research into the pathophysiology of RLS/WED has found that various genetic markers and existing dysfunctions in dopaminergic mechanisms and iron mechanisms play a central role. [bmj.com]

: On the pathophysiology of athetosis. J. Nerv. Ment. Dis., 135: 138–146, 1962. PubMed Google Scholar [9] Nieuwenhuys R. : Aspects of the morphology of the striatum. [link.springer.com]

Symptoms - Gemignani syndrome * Muscle weakness * Muscle wasting * Deafness * Increased reflexes * Short stature Causes - Gemignani syndrome Muscle overuse Infections Flu Fluid loss Dehydration Electrolyte imbalance Muscle wasting Prevention - Gemignani [checkorphan.org]

Diosmin is a natural venotonic that supports venous function, thereby preventing or reversing some of the changes of chronic venous disease (Carpentier 1998; Maksimovic 2008). [lifeextension.com]

Prevention Good nutrition with adequate intake of iron may prevent this disorder. Good nutrition should also include balanced diet and exercise. Treatment Treatment is primarily aimed at correcting the iron-deficiency anemia. [checkrare.com]

Diosmin is a natural venotonic that supports venous function, thereby preventing or reversing some of the changes of chronic venous disease. [healthrenewal.co.za]