It can present with intellectual disability, but some family members could present only with epilepsy ( Hardies et al 2013 ). [medlink.com]

Febrile convulsions in children: relationship of family history to type of convulsions and age at presentation. [psj.mums.ac.ir]

FS are not considered a form of epilepsy, but a FS can be the first presentation of subsequent epilepsy. At this time it is not possible to predict which child will develop an a febrile seizure after presenting with FS [ 7 ]. [omicsonline.org]

An SNP located 18 bp upstream of the splice-acceptor site for exon 3 was observed in 7 of the 226 patients bur was not present in 185 controls, suggesting possible association with a disease mutation. [experts.umich.edu]

Initial evaluation should determine whether features of a complex seizure are present and identify the source of fever. [aafp.org]

• Type A Personality

  Treatment Treatment very much depends on the seizure type or types each person has. For children (and adults) who only have febrile convulsions, regular treatment with epilepsy medicines is not usually required. [epilepsy.org.uk]

• Withdrawn

  INCLUDED Classification genetic, neurological Phenotypes Absence seizure ; Atonic seizures ; Autosomal dominant inheritance ; Febrile seizures ; Focal-onset seizure ; Generalized tonic-clonic seizures ; Variable expressivity Associated Genes SCN9A (Withdrawn [mousephenotype.org]

• Drop Attacks

  They may include febrile seizures (febrile convulsions); febrile seizures plus; tonic-clonic seizures; absence seizures; myoclonic seizures; atonic seizures (drop attacks); and focal (partial) seizures. [epilepsy.org.uk]

• Cognitive Disorder

  Various factors including long-lasting epilepsy and early age of onset may be associated with cognitive disorders. [content.iospress.com]

[…] considered in children aged 12-18 months, because clinical signs and symptoms of bacterial meningitis may be subtle in this age group In children older than 18 months, the decision to perform lumbar puncture rests on the clinical suspicion of meningitis See Workup [emedicine.medscape.com]

If the child has had a seizure, classify it by type (provoked or unprovoked, focal (localized) or generalized, etc.). to determine the appropriate diagnostic workup and treatment. [medicalhomeportal.org]

Treatment Treatment very much depends on the seizure type or types each person has. For children (and adults) who only have febrile convulsions, regular treatment with epilepsy medicines is not usually required. [epilepsy.org.uk]

CLOSE Medical Disclaimer The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. [diseaseinfosearch.org]

UCB Pharma SA assumes no responsibility of the views expressed and recommended treatments in these volumes. [epilepsy.com]

PPP2R5D, PPT1, PURA, SCN1A, SCN1B, SCN2A, SLC19A3, SLC2A1, SLC6A1, SLC6A8, SLC9A6, SMC1A, SPATA5, STX1B, SYNGAP1, TBC1D24, TCF4, TPP1, UBE3A, WDR45, ZEB2 Clinical Utility: Molecular confirmation of a clinical diagnosis To assist with decisions about treatment [genedx.com]

Treatment is only required when afebrile seizures appear, as there is no good evidence that anti-seizure medications are useful for febrile convulsions. [epilepsyqueensland.com.au]

Prognosis Seizures usually remit by mid-childhood (median 11 years). Development is usually normal. Differential diagnosis Febrile seizures. [epilepsy.com]

Prognosis The overall prognosis depends on the exact phenotype within the GEFS spectrum. In patients with mild phenotypes (FS, FS ) seizures often remit by adolescence. [orpha.net]

Prognosis The vast majority of febrile seizures are short and harmless. There is no evidence that short febrile seizures cause brain damage. [childneurologyfoundation.org]

Prognosis [ 1, 14 ] Generally the prognosis is very good: By definition, febrile seizures do not recur beyond the age of 5 years approximately. [patient.info]

Evidence suggests, however, that they have little connection with cognitive function, so the prognosis for normal neurologic function is excellent in children with febrile seizures. [1] Epidemiologic studies have led to the division of febrile seizures [emedicine.medscape.com]

Etiology Purely genetic disorder with profound heterogeneity. Inheritance is generally autosomal dominant with incomplete penetrance, but this may not be the only situation. Two loci are on chromosome 19q (GEFS ) and chromosome 2q (GEFS2). [epilepsy.com]

Etiology Mutations in SCN1A (2q24.3) (most commonly) and SCN1B (19q13.12) have been identified as causal in several families with GEFS . These genes encode two subunits of the neuronal sodium channel. [orpha.net]

Seizure Type Seizure type will guide the search for etiology and treatment choices if antiepileptic drug (AED) therapy is considered. [medicalhomeportal.org]

Etiology and Basic Mechanisms GEFS is a genetic disorder that has been recognized through study of large multiplex families where there is clinical genetic evidence of a gene of major effect. [neupsykey.com]

It may be difficult to determine if there is an underlying disorder with an initial FS, but the progressive course would indicate different etiology of seizure. [omicsonline.org]

Tsuboi T (1984) Epidemiology of febrile and afebrile convulsions in children in Japan. Neurology 34: 175-181. Berg AT, Shinnar S (1994) The contributions of epidemiology to the understanding of childhood seizures and epilepsy. [omicsonline.org]

Summary Epidemiology Prevalence is unknown but hundreds of cases have been described in the literature. Clinical description Phenotypes in patients can be variable, ranging from simple FS to epileptic encephalopathies including MAE and DS. [orpha.net]

No formal epidemiologic studies of GEFS have been performed. [neupsykey.com]

Evidence suggests, however, that they have little connection with cognitive function, so the prognosis for normal neurologic function is excellent in children with febrile seizures. [1] Epidemiologic studies have led to the division of febrile seizures [emedicine.medscape.com]

Epidemiology [ 3 ] Between 2% and 5% of European children have a febrile convulsion. [ 7 ] By definition, febrile convulsions occur between 6 month and 5 years of age. [patient.info]

The fact that many SUDEP cases are found prone in bed suggests that this position plays a role in the pathophysiology. [journal.frontiersin.org]

Preventive treatment involving daily use of antiseizure medicines is not recommended because of their potential for harmful side effects. [childneurologyfoundation.org]

If, however, preventing subsequent febrile seizures is essential, oral diazepam would be the treatment of choice. [emedicine.medscape.com]

Continuous or intermittent antiepileptic or antipyretic medication is not recommended for the prevention of recurrent febrile seizures. [aafp.org]

Giving these medicines around the clock is not recommended and won't prevent febrile seizures. [kidshealth.org]