Case report A 12-year-old boy presented to our dermatological outpatient department with erythema, pigmentation and roughness of the cheeks since the age of 2 years. [ijpd.in]

Obtain thorough guidance on clinical presentation and therapy for a full range of common and rare skin diseases. [books.google.de]

Due to its uncharacteristic presentation, it is rarely diagnosed clinically. Here we present one such case in a 50-year-old lady. She presented with a hard mobile lesion over her nose which was excised. The histologic picture is characterized... [connection.ebscohost.com]

The patient’s first pregnancy was aborted in the third month of pregnancy (14 months prior to presentation), but no skin lesions were reported at that time. [mdedge.com]

In general, hyperkeratosis is present with dilated hair follicles featuring keratin plugs ( Figure 2, Figure 3 ). A sparse dermal inflammatory infiltrate may be present. [dermatologyadvisor.com]

• Follicular Plugging

  Available from: Introduction Erythromelanosis follicularis faciei et colli (EFFC) is a rare disorder of unknown etiology characterized by the clinical triad of erythema, hyperpigmentation and follicular plugging on the face. [1] By 2013, some 55 cases [ijpd.in]

  Examination revealed small, discrete, spiny papules with follicular plugging present on a normal looking skin all over the body. In the natal cleft and pubic region, the lesions were grouped to form plaques with occasional pustules. [ijdvl.com]

  Erythromelanosis follicularis faciei et colli is characterized by the triad of hyperpigmentation, follicular plugging, and erythema of the face and neck. [4, 5] Race Keratosis pilaris (KP) has no widely described racial predilection or predominance. [emedicine.medscape.com]

  Histopathologic examination revealed hyperkeratosis and mild acanthosis of epidermis with follicular plugging and dilated infundibulum [Figure 5]. [scidoc.org]

  Clinical Manifestations Prominent follicular plugs, which may be filiform, are present from infancy or develop in early childhood on the nose, cheeks and later on the limbs and neck. [drmhijazy.com]

• Flushing

  This raises the question of whether flushing via autonomic dysregulation may have a role in the clinical manifestations. In summary, we describe 27 patients with KPR, a variant of KP that has not been previously emphasized in the medical literature. [jamanetwork.com]

• Calcinosis Cutis

  cutis (one or more firm, white-yellow papules, plaques or nodules / lesions may be tender and ulcerate, discharging chalk-like creamy material / can restrict joint movement / in severe cases tissue necrosis may occur) Weak patches of skin, including [pcds.org.uk]

• Burning Sensation

  There is a history of increase in the erythema and burning sensation on exposure to sunlight. He denied any similar history in his family members. There is no history of the application of any topical medication except emollients. [ijpd.in]

  The patient may experience a stinging or burning sensation of the skin, typically beginning shortly after exposure to sunlight and resolving rapidly when the skin is shaded. [nap.edu]

• Encephalopathy

  DA. 1974; VOL. 84; NO 4; PP. 564-567 Document type Article Language English Keyword (fr) SYNDROME HEREDITAIRE NANISME ENCEPHALOPATHIE ARRIERATION MENTALE KERATOSE FOLLICULAIRE GENERALISE HOMME MALFORMATION ENCEPHALE PEAU PATHOLOGIE SYSTEME NERVEUX [pascal-francis.inist.fr]

• Cryptorchidism

  Traupe was able, thanks to his unceasing clinical curiosity, to describe many novel aspects within the field of ichthyosis, and I took pride in coauthoring papers on new items such as cryptorchidism as a fea ture associated with X-linked recessive ichthyosis [books.google.de]

  External genitalia are almost always normal; few cases presented with cryptorchidism [ 3, 14, 16, 17 ], and one with a hypospadias [ 17 ]. Dental development is normal. [ojrd.biomedcentral.com]

Her symptoms were concerning for a paraneoplastic eruption; workup revealed an elevated CA 125 level and an ovarian mass on abdominal computed tomography scan... [readbyqxmd.com]

• Lymphocytic Infiltrate

  The various findings on skin biopsy, which have been reported include acanthosis, hyperkeratosis, follicular plugging, increased pigmentation in the basal membrane, perivascular and periadnexal lymphocytic infiltrate. [8] However, in our case skin biopsy [ijpd.in]

  Coloration HES G x 200 - Lymphocytic Infiltrate Inflammatory Fibrosis Around a Hair Shaft Atrophic. [scidoc.org]

  Biopsy of one of the crateriform papules showed ortho- and parakeratotic hyperkeratosis overlying a slightly acanthotic epidermis with a preserved granular layer and a very mild perivascular lymphocytic infiltrate in the upper dermis (Figures 3 and 4) [docksci.com]

  infiltrate in the dermis. 5 Hyperkeratosis, parakeratosis, and acanthosis may be present in the follicles. 5 CLINICAL MANIFESTATIONS The onset of lichen spinulosus is usually sudden. [consultant360.com]

  Lesions may be hypopigmented centrally) Scleroderma syn. morphoea (trunk most common site / not truly annular, however, the waxy ivory white patches may have a lilac-coloured edge giving an annular-like appearance) Jessner’s lymphocytic infiltrate (face [pcds.org.uk]

Broaden your knowledge with updated information on serological diagnosis of pemphigus, TNF-I for hidradenitis suppurativa, the use of immunosuppressives for atopic dermatitis, excimer laser for the treatment of vitiligo and much more. [books.google.de]

The treatment modalities for EFFC have not been established yet. [ijpd.in]

However, a dermatologist may be able to suggest treatment options to improve the appearance of your skin. Follicular keratosis Scalpel surgery or laser treatment can remove these lesions, though treatment isn’t necessary. [healthline.com]

To get the best results from the laser treatments, your dermatologist may add a few microdermabrasion sessions to your treatment plan. [aad.org]

2018 Jan 16 [PubMed] Oral alitretinoin for the treatment of recalcitrant pityriasis rubra pilaris., Schmitt L,Inhoff O,Dippel E,, Case reports in dermatology, 2011 Apr 18 [PubMed] Infliximab monotherapy as first-line treatment for adult-onset pityriasis [knowledge.statpearls.com]

Prognosis Overall prognosis is good. Many cases resolve with increasing age. However, others may persist into late adulthood with intermittent exacerbations and remissions. [emedicine.medscape.com]

The prognosis is excellent in healthy, immunocompetent individuals. Notes: DOI PMID Vito Di Lernia, Cinzia Ricci (2006) On atopic and idiopathic extensive pityriasis alba. [publicationslist.org]

[…] disease (keratosis follicularis), Gianotti-Crosti syndrome, pityriasis rubra pilaris, phrynoderma (hypovitaminosis A), follicular mucinosis, miliary papular syphilis, lichen scrofulosorum, multiple minute digitate hyperkeratosis, and trichophytids. 1,5,15 PROGNOSIS [consultant360.com]

The prognosis of phrynoderma is excellent with appropriate treatment. [dermatologyadvisor.com]

Prognosis Life expectancy in patients with IFAP syndrome can vary from death in the neonatal period to normal surviving. The oldest reported patient was 33 years old [ 10 ]. Cardiopulmonary complications were the main cause of death. [ojrd.biomedcentral.com]

Available from: Introduction Erythromelanosis follicularis faciei et colli (EFFC) is a rare disorder of unknown etiology characterized by the clinical triad of erythema, hyperpigmentation and follicular plugging on the face. [1] By 2013, some 55 cases [ijpd.in]

Etiology Phrynoderma is generally accepted as a consequence of malnutrition, but the exact nutritional deficiency is debated. [dermatologyadvisor.com]

Psoriasis Etiology Findings/ Distribution Diagnostic Clues Management Activation of lymphocytes causes shortened epidermal life cycle (10 times shorter than normal), leading to epidermal hyperproliferation Silvery scales on red plaques More common on [hiv.va.gov]

In the majority of cases, the etiology is idiopathic. [consultant360.com]

Seven common skin conditions that can have environmental etiologies are presented in this monograph. [nap.edu]

[…] spinulosus is a dermatosis characterized by follicular keratotic spiny papules that are grouped into large symmetrical plaques. 1 This disorder was first described by Crocker in 1883, and the term “lichen spinulosus” was coined by Adamson in 1905. 2 EPIDEMIOLOGY [consultant360.com]

Certain drugs, like nilotinib, have been implicated as causes of keratosis pilaris or keratosis pilaris atrophicans. [3] Epidemiology Frequency Keratosis pilaris (KP) is overall a very common condition and is present worldwide. [emedicine.medscape.com]

Background Epidemiology Dermatological diseases are common among HIV-infected persons. In one large population study, 69% of HIV-infected patients had cutaneous disease. Seborrheic dermatitis is the most common dermatologic diagnosis. [hiv.va.gov]

Epidemiological data does not support a gender predilection for phrynoderma. What is the Cause of the Disease? Etiology Phrynoderma is generally accepted as a consequence of malnutrition, but the exact nutritional deficiency is debated. [dermatologyadvisor.com]

Epidemiology The association of ichthyosis follicularis, atrichia, and photophobia was first reported as a syndrome by MacLeod in 1909 in three boys [ 1 ]. [ojrd.biomedcentral.com]

The process of lionization may explain expression of KFSD in women.The pathophysiology of the destruction of the pilar follicle is not well known yet. [medigoo.com]

[…] epidermolytic leukoplakia Terminology Other names: Epidermolytic ichthyosis Bullous congenital ichthyosiform erythroderma Bullous ichthysosis Bullous erythroderma ichthyosiformis congenita of Brocq Disorder of cornification type 3 Vorner's syndrome Pathophysiology [pathologyoutlines.com]

Pathophysiology Keratosis pilaris (KP) is a genetically based disorder of hyperkeratinization of the skin. An excess formation and/or buildup of keratin is thought to cause the abrasive goose-bump texture of the skin. [emedicine.medscape.com]

[…] minute digitate hyperkeratosis - a peculiar entity as a paraneoplastic syndrome, resolving after successful treatment of the accompanying laryngeal carcinoma.6 The former is most likely an autossomal dominant dermatosis, even though its genetic basis and pathophysiology [docksci.com]

Pathophysiology The latency period for development of cancerous lesions can be 20 years or more. [nap.edu]

You’ll also need to take some precautions to prevent flare-ups. The following tips can help. Tips to prevent flare-ups Moisturize your skin: Keratosis pilaris often flares when the skin becomes dry. Applying a moisturizer can prevent dry skin. [aad.org]

Dietary advice is essential for prevention of recurrence in susceptible individuals. This case highlights the clinical presentation of Scurvy, an uncommon disease of modern times but one which is easily treatable. [jlgh.org]

Consistently following good bathing habits, such as moisturizing areas that are prone to flare-ups, may also help prevent future episodes. [healthline.com]

Coritinous oral tetracycline (500 mg daily) was found to prevent hair loss and promote regrowth of hair in one case. [2] Systemic retinoids may be useful and deserve a trial. References 1. Kukkanen K. [ijdvl.com]

Essential fatty acid deficiency is very rare as even small amounts of dietary intake can prevent deficiency. [podiatrytoday.com]