Presentation
A clonal lymphoplasmocytic proliferation, e.g. plasmacytoma, is present in the majority of cases. Here we report on a 19-year-old male who presented with generalized seizures and an enhancing white matter lesion on MRI scans. [ncbi.nlm.nih.gov]
Entire Body System
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Hypoxemia
Ictal hypoxemia occurred in 25% of seizures and was associated with normal MRI (p 0.01), longer seizure duration (p 0.049), and ictal tachycardia (p 0.003). Such findings may have implications for understanding the pathogenesis of SUDEP. [ncbi.nlm.nih.gov]
Cardiovascular
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Tachycardia
Ictal hypoxemia occurred in 25% of seizures and was associated with normal MRI (p 0.01), longer seizure duration (p 0.049), and ictal tachycardia (p 0.003). Such findings may have implications for understanding the pathogenesis of SUDEP. [ncbi.nlm.nih.gov]
Urogenital
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Uremia
Uremia in patients in the early posttransplant period appears to predispose them to seizures. Seizures that happened to our two uremic patients after transplant suggest that they had been induced by muromonab-CD3 administration. [ncbi.nlm.nih.gov]
Neurologic
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Seizure
For different seizure types, focal to bilateral tonic-clonic seizures (P 0.020) and myoclonic-atonic seizures (P 0.002) might correlate with unfavourable outcomes. [ncbi.nlm.nih.gov]
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Tonic-Clonic Seizure
Similar focal increases were also seen in imaging of spontaneous secondarily generalized tonic-clonic seizures. [ncbi.nlm.nih.gov]
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Asthenia
Progesterone was well tolerated by 23 of the 25 women and had readily reversible dose-related side effects of asthenia and emotional depression in two. [ncbi.nlm.nih.gov]
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Tonic Posturing
RESULTS: The sequence of tonic postures, as well as the sequence of tonic and clonic activity, was variable in SGSs of mesial temporal origin. [ncbi.nlm.nih.gov]
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Sleep Disturbance
PURPOSE: The frequency of dream recall (DR) in patients with brain diseases has proved to be indicative of the relation between sleep disturbances and the functioning of cognitive processes during sleep. [ncbi.nlm.nih.gov]
Workup
With these data, the current American College of Emergency Physicians (ACEP) guidelines on the workup of new-onset seizures were applied to determine whether they could safely be used in patients with AIDS. [ncbi.nlm.nih.gov]
EEG
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Epileptiform Activity
A traditional, accepted perspective on epileptiform activity holds that hypersynchrony covering large brain regions is a hallmark of generalized seizures. [ncbi.nlm.nih.gov]
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Generalized Epileptiform Discharges
We describe a patient with generalized seizures who in the same EEG had spindles transforming into generalized epileptiform discharges and generalized epileptiform discharges transforming into spindles. [ncbi.nlm.nih.gov]
Other Pathologies
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White Matter Lesions
Here we report on a 19-year-old male who presented with generalized seizures and an enhancing white matter lesion on MRI scans. [ncbi.nlm.nih.gov]
Treatment
OBJECTIVE: To evaluate safety, tolerability, seizure frequency, and regional variations in treatment responses with the AMPA antagonist, perampanel, in a large extension study during up to 3 years of treatment. [ncbi.nlm.nih.gov]
Prognosis
All preoperative evaluation data correlated to generalized seizures and postoperative prognosis were collected and analysed. [ncbi.nlm.nih.gov]
Etiology
The purpose of this investigation was to determine the relative importance of this medication as the etiology of new-onset seizures relative to other drugs and new-onset seizures in general. The study design was a retrospective case series. [ncbi.nlm.nih.gov]
Pathophysiology
Recognition and characterization of individual diurnal seizure patterns offer new diagnostic and therapeutic options, including EEG or long-term video EEG monitoring scheduling, differential (day/night) medication dosing, and a better understanding of pathophysiologic [ncbi.nlm.nih.gov]