Presentation [ 4 ] GCA typically presents with recent onset of temporal headache, myalgia, malaise or fever. Typical features may be absent or subtle. [patient.info]

Liu et al. [ 5 ] presented a review of 24 cases of GCA who presented with dissection. The study serves as a historical review of the natural history of the disease. [ejcts.oxfordjournals.org]

Here we present a case of GCA combined with ascending aortic dissection and rupture 3 weeks after diagnosis. [jstage.jst.go.jp]

Visual symptoms are less common at initial presentation, but are of critical importance. [bpac.org.nz]

In the latter half of this article, we introduce two patients presenting with such atypical presentations. One could be diagnosed as occult GCA, and the other was diagnosed as silent GCA with large vessel type. [ci.nii.ac.jp]

[…] role of imaging studies in the assessment of giant-cell arteritis ( e.g., ultrasonography or MRI of the temporal arteries, F18 PET scan) has received increasing attention but it remains uncertain how they should best be integrated into the diagnostic workup [orpha.net]

Since the previous reports have shown frequent aortic involvement even in the early stages of the disease, it is reasonable that all GCA patients should have an initial diagnostic workup focused on the presence of aortitis, given that GCA aortitis remains [jmedicalcasereports.biomedcentral.com]

[…] an effective ‘emergency’ treatment option to prevent damage such as vision loss. [roche.com]

Diagnosis and treatment Treatment for giant cell arteritis will usually begin as soon as possible. This may mean that treatment begins before a diagnosis is confirmed. [your.md]

Thanks to our dedicated donors, we are now able to offer GCA patients financial relief in the cost of their treatment.” [healthwellfoundation.org]

“With no new treatments in more than 50 years, this approval could be transformational for people with GCA and for their physicians.” [globalgenes.org]

A treatment duration of at least one to two years, often longer, should be expected. [bpac.org.nz]

This is important in ensuring a favorable prognosis In most cases, corticosteroid treatment can be stopped after 1-2 years. [dovemed.com]

[…] shows mural inflammation very well 2,4 mean wall thickness increased in the affected region luminal diameter correspondingly decreased in the affected region reported approximate sensitivity and specificity is 80% and 97%, respectively 2 Treatment and prognosis [radiopaedia.org]

“Maybe it’s because women exprThere is no evidence right now that if you were to stop the disease entirely that the prognosis of our patients would improve. What Goes Wrong? Dr. [the-rheumatologist.org]

Prognosis The disease is chronic and the clinical course is highly variable. Approximately 50% of patients experience subsequent disease flares. Visual loss is the most feared complication. [orpha.net]

Prognosis The visual prognosis is highly dependent on the rapidity with which steroids are started, and the status of the patient’s vision upon presentation. [eyewiki.aao.org]

Etiology The etiology of giant cell arteritis is unknown. Studies have linked genetic factors, infectious agents and a prior history of cardiovascular disease to the development of giant cell arteritis. [orpha.net]

(Etiology) The exact cause of Giant Cell Arteritis is largely unknown However, it is known that the risk of developing GCA increases with an advancing age. [dovemed.com]

Etiology The underlying etiology of GCA is is complex and has been widely researched, yet is still not well understood. [eyewiki.aao.org]

In this review we discuss the pathophysiology of this disease and also the issues of epidemiology and sex differences. [ucdavis.pure.elsevier.com]

From the *Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA; and †Division of Rheumatology, Department of Medicine, and Divisions of ‡Biostatistics and §Epidemiology [journals.lww.com]

Summary Epidemiology GCA is the most common adulthood vasculitis with an annual incidence of 1/3,000-1/25,000 adults over 50 years old. It is more frequent in populations of northern European background. [orpha.net]

Epidemiology Giant Cell Arteritis Cardiovascular Disease Statistics from Altmetric.com Epidemiology Giant Cell Arteritis Cardiovascular Disease Introduction Giant cell arteritis (GCA) is the most common form of vasculitis in the UK, with an incidence [ard.bmj.com]

In an epidemiological study [ 2 ] from Olmsted County, Minnesota, USA, the local county of the Mayo Clinic, the annual incidence of TA was found to be 17/100 000 person-years. [ejcts.oxfordjournals.org]

In this review we discuss the pathophysiology of this disease and also the issues of epidemiology and sex differences. [ucdavis.pure.elsevier.com]

J Rheumatol 2015 ; 42 : 1213 – 7. 9 Giant cell arteritis: a review of classification, pathophysiology, geoepidemiology and treatment. Autoimmun Rev 2012 ; 11 : A544 – 54. 10. [ejcts.oxfordjournals.org]

Polymyalgia rheumatica can also exist as a distinct entity with no evidence of vascular involvement. 6 This chapter presents the epidemiology, pathophysiology, clinical manifestations, and treatment options for GCA, with particular reference to manifestations [clinicalgate.com]

Giant cell arteritis: a review of classification, pathophysiology, geoepidemiology and treatment. Autoimmun Rev. 2012 May;11(6-7):A544-54. Epub 2012 Jan 21. Kesten F, Aschwanden M, Gubser P, Glatz K, Daikeler T, Hess C. [medicine.uiowa.edu]

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases: Pathophysiology, Clinical Aspects and Therapeutic Approaches. Academic Press. p. 367. ISBN 9780128032688. [en.wikipedia.org]

Early recognition and adequate treatment of the condition is thus necessary to prevent patients' loss of independence and to maintain their quality of life. [books.google.com]

This study will evaluate the effectiveness of abatacept in treating GCA and TAK and preventing disease relapse. [clinicaltrials.gov]

Low-dose aspirin (81 to 100 mg orally once a day) may help prevent ischemic events and should be prescribed for all patients unless contraindicated. 1. [msdmanuals.com]

If you're diagnosed with giant cell arteritis, starting treatment as soon as possible can usually help prevent vision loss. Causes With giant cell arteritis, the lining of arteries becomes inflamed, causing them to swell. [mayoclinic.org]

[…] bone loss and a proton pump inhibitor to prevent stomach problems. [4] It affects about 1 in 15,000 people over the age of 50 a year. [2] The condition typically only occurs in those over the age of 50 being most common among those in their 70s. [4] [en.wikipedia.org]